PRPF38A

General Information

Gene Name       : PRPF38A
Gene ID             : ENSG00000134748.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PRPF38A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PRPF38AENSG00000134748.1235.5452.2943.91ENCSR000AEF
HepG2PRPF38AENSG00000134748.1244.3645.2244.79ENCSR985KAT
K562PRPF38AENSG00000134748.1286.3989.1987.79ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PRPF38A is not avaliable on ENCORE database.



Proteins bound to RNA
  • PRPF38A RNA is bound by 22 proteins.  







eCLIP assay for PRPF38A is not avaliable on ENCORE database.





22 proteins are bound to PRPF38A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr15288250452882583+3'-UTR3.079493.70380HepG2LARP4
chr15288238352882432+3'-UTR3.529174.26355K562XRCC6
chr15288385952883920+3'-UTR3.012783.11628K562KHSRP
chr15288247752882531+3'-UTR3.112003.53131HepG2SUB1
chr15288231952882376+3'-UTR,CDS,intron-Proximal4.437704.38106HepG2PPIG
chr15288384852883931+3'-UTR4.054056.87384K562CSTF2T
chr15287032152870408+5'-UTR5.1650718.78695K562U2AF2
chr15287035552870430+5'-UTR,CDS3.661919.52855K562GRWD1
chr15287025352870283+5'-UTR4.513633.88168K562DDX3X
chr15287035252870407+5'-UTR4.332514.69889HepG2GRWD1
chr15287825652878297+CDS,intron-Proximal4.337623.89826HepG2BCLAF1
chr15287960152879660+CDS3.125557.47702K562UCHL5
chr15287051052870592+CDS,intron-Proximal5.512477.70650HepG2PRPF8
chr15287049152870547+CDS3.663583.10677K562SRSF1
chr15287432652874354+CDS,intron-Distal3.184887.01182K562ZNF622
chr15288053052880556+CDS,intron-Proximal3.799478.13013K562AQR
chr15287423552874261+CDS,intron-Distal,intron-Proximal3.304206.13643K562AQR
chr15287809052878194+CDS,intron-Proximal3.782468.97396K562SF3B4
chr15287680852876874+CDS,intron-Distal,intron-Proximal3.827184.96321K562LIN28B
chr15288231952882356+CDS,intron-Proximal3.670075.59924K562GRWD1
chr15288230652882352+CDS,intron-Proximal3.149723.44687K562SRSF1
chr15287955552879658+CDS3.695796.58996HepG2GRWD1
chr15288100852881058+CDS,intron-Proximal3.062483.22545HepG2PPIG
chr15287423152874290+CDS,intron-Distal,intron-Proximal3.260015.58706K562U2AF1
chr15287825252878295+CDS3.555107.58409K562UCHL5
chr15287129652871359+CDS,intron-Proximal6.3382616.66865K562SF3B4
chr15287425352874291+CDS,intron-Distal3.019434.50936K562SF3B4
chr15287955052879664+CDS,intron-Proximal3.0580810.89698K562DDX24
chr15287954952879586+CDS,intron-Proximal4.554104.78529HepG2BCLAF1
chr15287963752879666+CDS,intron-Proximal4.258643.49905HepG2PPIG
chr15287825752878290+CDS4.5678010.28502K562ZNF622
chr15287958752879663+CDS3.2226719.54554K562ZNF622
chr15287054952870598+CDS,intron-Proximal3.8073111.47097K562AQR
chr15287149152871512+CDS,intron-Distal,intron-Proximal3.034474.91034K562YBX3
chr15288047352880531+CDS3.355414.02291HepG2GRWD1
chr15288029252880313+CDS,intron-Proximal3.299536.45823K562ZNF622
chr15288043452880499+CDS3.393963.93645HepG2PPIG
chr15287959752879658+CDS4.498865.46067K562SRSF1
chr15287802252878057+intron-Distal3.790449.27366K562KHSRP
chr15287442052874462+intron-Distal,intron-Proximal3.591954.58287K562PRPF8
chr15287441152874475+intron-Distal,intron-Proximal4.4193910.81737K562TIA1
chr15287837852878428+intron-Distal,intron-Proximal3.808096.93060K562EFTUD2
chr15287447852874520+intron-Distal4.453254.48529K562TIA1
chr15287805752878112+intron-Distal,intron-Proximal3.279857.14419K562KHSRP
chr15287059252870657+intron-Distal,intron-Proximal3.405013.31456K562TIA1
chr15287438252874403+intron-Distal,intron-Proximal4.916115.69951K562AQR
chr15287440952874464+intron-Distal,intron-Proximal4.395796.48405K562AQR
chr15287421152874235+intron-Distal,intron-Proximal4.331154.98250K562AQR
chr15287968152879756+intron-Proximal3.364115.58816K562PRPF8
chr15287060352870639+intron-Proximal4.792564.86944K562AQR
chr15287967952879707+intron-Proximal3.421436.13643K562AQR
chr15287833352878357+intron-Proximal4.343293.07235K562EFTUD2
chr15288036952880425+intron-Proximal4.532208.05832K562SF3B4
chr15288058152880601+intron-Proximal4.172063.11721K562AQR
chr15288055652880574+intron-Proximal5.784599.95272K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PRPF38A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PRPF38A is not available on ENCORE database.

  • 71 RBPs can affect the levels of PRPF38A.  








The Knockdown/knockout RNA-Seq assay for PRPF38A is not available on ENCORE database.





71 RBPs can affect the gene expression of PRPF38A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PRPF38AENSG00000134748.12675.56750903.02830-0.418705.111304.33420HepG2ACO1
PRPF38AENSG00000134748.121587.513401042.767500.606305.154504.45720HepG2AKAP1
PRPF38AENSG00000134748.12467.29690752.11010-0.686605.781604.53470HepG2BCLAF1
PRPF38AENSG00000134748.121106.79950819.719600.433103.252602.41780HepG2CIRBP
PRPF38AENSG00000134748.121158.20570696.050300.734504.859003.84020HepG2CNOT7
PRPF38AENSG00000134748.12698.536901080.62660-0.629506.495305.47390HepG2CPSF6
PRPF38AENSG00000134748.12721.26500534.618100.431902.846001.75580HepG2CSTF2
PRPF38AENSG00000134748.121320.14880998.884700.402202.820602.18910HepG2DDX3X
PRPF38AENSG00000134748.12494.89290851.11620-0.782207.166105.99030HepG2DDX55
PRPF38AENSG00000134748.12836.159801118.08350-0.419203.324302.22370HepG2DDX5
PRPF38AENSG00000134748.12567.00720858.08070-0.597704.366103.60430HepG2DDX6
PRPF38AENSG00000134748.12590.52440755.38150-0.355202.988202.26210HepG2DNAJC21
PRPF38AENSG00000134748.12633.04020748.80000-0.242302.002001.43060HepG2DNAJC2
PRPF38AENSG00000134748.12510.77530824.87580-0.691506.071405.21150HepG2EIF2S1
PRPF38AENSG00000134748.12560.48920887.56380-0.663204.349603.49870HepG2EIF4B
PRPF38AENSG00000134748.12811.18300592.672200.452703.673902.77720HepG2FUBP3
PRPF38AENSG00000134748.12891.504201224.94790-0.458403.326202.62920HepG2GPKOW
PRPF38AENSG00000134748.12879.409201141.87510-0.376804.439703.30510HepG2HNRNPA2B1
PRPF38AENSG00000134748.12924.809801133.89350-0.294102.828702.10300HepG2HNRNPF
PRPF38AENSG00000134748.121125.04570863.980800.380802.778402.07930HepG2HNRNPK
PRPF38AENSG00000134748.12810.274801168.99280-0.528804.642003.84790HepG2HNRNPLL
PRPF38AENSG00000134748.12716.57160842.69170-0.233901.823001.32140HepG2HNRNPU
PRPF38AENSG00000134748.12813.486501116.56620-0.456904.671003.75270HepG2IGF2BP1
PRPF38AENSG00000134748.12667.22240825.52530-0.307103.071602.00000HepG2KIF1C
PRPF38AENSG00000134748.121309.469501787.67780-0.449102.966502.10520HepG2LARP4
PRPF38AENSG00000134748.12358.73790781.67940-1.123608.468006.51260HepG2NONO
PRPF38AENSG00000134748.12351.33980843.37240-1.2633017.4246015.65890HepG2PABPC4
PRPF38AENSG00000134748.121278.86470951.255600.426905.800104.72320HepG2PRPF4
PRPF38AENSG00000134748.12690.69470848.10090-0.296202.580602.04910HepG2PTBP1
PRPF38AENSG00000134748.121033.480201248.45980-0.272603.384202.74210HepG2PUM1
PRPF38AENSG00000134748.12771.67160919.80330-0.253302.249101.68080HepG2PUS1
PRPF38AENSG00000134748.121091.58160918.487300.249001.838101.31330HepG2QKI
PRPF38AENSG00000134748.121043.42100833.596400.323802.469601.82850HepG2RBM25
PRPF38AENSG00000134748.121131.05650879.081900.363504.100903.36920HepG2RECQL
PRPF38AENSG00000134748.12956.555201221.40880-0.352602.211801.59200HepG2RPLP0
PRPF38AENSG00000134748.12417.90050689.59620-0.722606.230705.34990HepG2RPS19
PRPF38AENSG00000134748.12943.890401157.05660-0.293801.918601.32410HepG2SF3B1
PRPF38AENSG00000134748.12720.24780882.95990-0.293902.422601.86420HepG2SF3B4
PRPF38AENSG00000134748.121553.78410921.628200.7534017.5169016.54190HepG2SRSF1
PRPF38AENSG00000134748.12581.64790810.79410-0.479203.935802.82640HepG2SUPT6H
PRPF38AENSG00000134748.12660.05300847.23210-0.360202.088801.49010HepG2SUPV3L1
PRPF38AENSG00000134748.12287.12090567.84500-0.983809.453707.83420HepG2TFIP11
PRPF38AENSG00000134748.12672.69320826.15940-0.296502.629602.07650HepG2TRIM56
PRPF38AENSG00000134748.121526.079801027.034800.571206.152405.23240HepG2U2AF1
PRPF38AENSG00000134748.12881.009701216.12540-0.465103.265302.35680HepG2UBE2L3
PRPF38AENSG00000134748.12727.773001059.11510-0.541308.588907.47070HepG2UPF1
PRPF38AENSG00000134748.121217.350301022.530300.251502.333101.77260HepG2UTP3
PRPF38AENSG00000134748.12453.304901164.82050-1.3616049.5475047.97740HepG2ZNF622
PRPF38AENSG00000134748.124819.742503541.178500.4446011.7445010.66940K562AGGF1
PRPF38AENSG00000134748.125826.380703684.795900.6609012.0606010.56560K562AKAP8L
PRPF38AENSG00000134748.124934.760303866.311900.351904.635703.41800K562ATP5C1
PRPF38AENSG00000134748.122335.049102830.62250-0.277704.252403.04540K562BCLAF1
PRPF38AENSG00000134748.124756.758405754.24320-0.274604.116502.74800K562CPEB4
PRPF38AENSG00000134748.122963.037404353.63040-0.555109.844208.34960K562CPSF6
PRPF38AENSG00000134748.124802.059803964.858900.276304.192603.08350K562DKC1
PRPF38AENSG00000134748.123201.158204233.40590-0.403207.491706.39340K562EIF2S2
PRPF38AENSG00000134748.122667.459702194.116000.281703.042102.20770K562EIF3G
PRPF38AENSG00000134748.122372.465801939.723800.290402.767601.42800K562FUS
PRPF38AENSG00000134748.123936.607302728.130100.528904.205603.29300K562G3BP2
PRPF38AENSG00000134748.123149.201904156.58420-0.400404.720803.68870K562GPKOW
PRPF38AENSG00000134748.124803.512205641.59300-0.232002.154601.48240K562GRSF1
PRPF38AENSG00000134748.122434.719903244.07170-0.414005.096404.30850K562HNRNPC
PRPF38AENSG00000134748.125245.158306338.92640-0.273302.434501.68410K562HSPD1
PRPF38AENSG00000134748.125595.252303910.352200.516805.464604.21930K562KIF1C
PRPF38AENSG00000134748.125233.361504380.601400.256502.577801.70540K562MBNL1
PRPF38AENSG00000134748.125521.757003070.496400.846604.818403.55190K562NAA15
PRPF38AENSG00000134748.121616.191502356.13000-0.543805.538403.55780K562NONO
PRPF38AENSG00000134748.123538.038002787.611400.343803.434702.34470K562PCBP2
PRPF38AENSG00000134748.123147.771202326.985600.435804.528303.56960K562PRPF8
PRPF38AENSG00000134748.128160.027503654.026801.1590031.3925029.54110K562PUS1
PRPF38AENSG00000134748.126179.075303560.530400.7952025.9988024.10370K562RBM15
PRPF38AENSG00000134748.123412.577702588.192200.398805.010403.14600K562RBM25
PRPF38AENSG00000134748.122233.960602653.20940-0.248102.187801.31010K562RCC2
PRPF38AENSG00000134748.123029.801804541.24140-0.5839014.8972013.10940K562SF3A3
PRPF38AENSG00000134748.121943.610502515.22010-0.371903.535702.33800K562SRFBP1
PRPF38AENSG00000134748.124729.551902983.844900.6644013.7237012.15070K562SRSF1
PRPF38AENSG00000134748.123740.140302987.938400.323803.934902.95400K562SYNCRIP
PRPF38AENSG00000134748.122437.228602913.07840-0.257302.379301.62750K562TIA1
PRPF38AENSG00000134748.123813.070602645.028100.527605.158303.57100K562U2AF1
PRPF38AENSG00000134748.123389.406702731.547400.311203.643502.71980K562U2AF2
PRPF38AENSG00000134748.124281.096404880.16600-0.188902.763202.04440K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PRPF38A is not available on ENCORE database.





7 RBPs can affect the splicing of PRPF38A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPRPF38AENSG00000134748.12chr1+528802925288031952879550528796635288043352880531-0.100000.000510.01155excludedHepG2U2AF1
SEPRPF38AENSG00000134748.12chr1+528802925288031952879550528796635288043352880531-0.127000.000020.00055excludedHepG2U2AF2
SEPRPF38AENSG00000134748.12chr1+5287683552876872528713515287138552878185528782960.064000.003490.03460includedK562AQR
SEPRPF38AENSG00000134748.12chr1+528802925288031952879480528796635288043352880531-0.090000.000000.00000excludedK562AQR
SEPRPF38AENSG00000134748.12chr1+5287093152870985528702355287055152871351528715110.060000.000000.00021includedK562SUPV3L1
SEPRPF38AENSG00000134748.12chr1+528802925288031952879550528796635288043352880531-0.071000.001750.04735excludedHepG2SF3A3
SEPRPF38AENSG00000134748.12chr1+5287093152870985528702355287055152871351528713850.077000.000000.00000includedK562TARDBP
SEPRPF38AENSG00000134748.12chr1+5287093152870985528702355287055152871351528715110.075000.000000.00000includedK562HNRNPU
SEPRPF38AENSG00000134748.12chr1+5287093152870985528702355287055152871351528715110.063000.001380.05507includedHepG2HNRNPU
A3SSPRPF38AENSG00000134748.12chr1+5287675652876872528767865287687252874205528743620.066000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PRPF38A is not avaliable on ENCORE database.