PPTC7

General Information

Gene Name       : PPTC7
Gene ID             : ENSG00000196850.5
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPTC7)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPTC7ENSG00000196850.523.9320.3022.12ENCSR000AEF
HepG2PPTC7ENSG00000196850.57.0011.489.24ENCSR985KAT
K562PPTC7ENSG00000196850.513.1713.1413.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPTC7 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPTC7 RNA is bound by 14 proteins.  







eCLIP assay for PPTC7 is not avaliable on ENCORE database.





14 proteins are bound to PPTC7 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12110973219110973293-3'-UTR,intron-Distal3.527224.54145K562DDX6
chr12110973411110973468-3'-UTR,intron-Distal5.219998.15847K562PUM2
chr12110971079110971164-3'-UTR,intron-Distal6.1693015.61756K562PUM2
chr12110973210110973306-3'-UTR,intron-Distal4.258805.51967HepG2FUBP3
chr12110971473110971571-3'-UTR,intron-Distal3.021133.07368K562TARDBP
chr12110970934110971047-3'-UTR,intron-Distal3.661943.47315HepG2CSTF2
chr12110974705110974826-3'-UTR,intron-Distal3.306637.79680K562RBM15
chr12110971686110971781-3'-UTR,intron-Distal4.080563.97974HepG2RBFOX2
chr12110973241110973292-3'-UTR,intron-Distal3.483025.43236K562PUM2
chr12110971690110971783-3'-UTR,intron-Distal3.906897.04449K562RBFOX2
chr12111020922111021077-5'-UTR,intron-Distal5.2976015.31047HepG2DDX3X
chr12111020825111020880-5'-UTR,CDS,intron-Distal5.351196.02643HepG2DDX3X
chr12110974869110974939-CDS,intron-Distal4.8298213.13232K562SF3B4
chr12110977579110977648-CDS,intron-Distal,intron-Proximal4.926424.02817HepG2PRPF8
chr12110977683110977784-CDS,intron-Distal,intron-Proximal3.569126.12893K562BUD13
chr12110974863110974928-CDS,intron-Distal3.728723.05149K562SMNDC1
chr12110989547110989595-CDS,intron-Distal,intron-Proximal4.743364.65563K562AQR
chr12110977570110977632-CDS,intron-Distal,intron-Proximal5.234659.11053K562PRPF8
chr12110977731110977804-CDS,intron-Distal,intron-Proximal5.320456.91748K562SF3B4
chr12111015677111015743-intron-Distal4.006673.87294K562TARDBP
chr12110983583110983684-intron-Distal,intron-Proximal4.284596.48405K562AQR
chr12110977463110977590-intron-Distal,intron-Proximal3.835624.75435K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPTC7 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPTC7 is not available on ENCORE database.

  • 89 RBPs can affect the levels of PPTC7.  








The Knockdown/knockout RNA-Seq assay for PPTC7 is not available on ENCORE database.





89 RBPs can affect the gene expression of PPTC7 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPTC7ENSG00000196850.4527.95660713.08570-0.433704.644603.89530HepG2ACO1
PPTC7ENSG00000196850.41669.600901150.714400.536904.248803.60920HepG2AKAP1
PPTC7ENSG00000196850.4553.25750781.67110-0.498602.937601.96850HepG2BCCIP
PPTC7ENSG00000196850.4642.08860904.58150-0.494503.679702.79700HepG2CIRBP
PPTC7ENSG00000196850.4469.83440628.85370-0.420603.397402.26950HepG2YBX3
PPTC7ENSG00000196850.41090.26980876.932700.314002.947402.28740HepG2CELF1
PPTC7ENSG00000196850.4346.44270545.18330-0.654105.484404.56320HepG2DDX21
PPTC7ENSG00000196850.41904.956801102.305600.789109.913108.79480HepG2DDX3X
PPTC7ENSG00000196850.4327.50090768.54190-1.2306013.9208012.36160HepG2DDX55
PPTC7ENSG00000196850.4472.42170612.03280-0.373503.518002.79800HepG2DNAJC2
PPTC7ENSG00000196850.4434.24610910.28170-1.0678013.4054012.16880HepG2EIF2S1
PPTC7ENSG00000196850.41274.71690930.256300.454406.079004.92560HepG2EIF4G1
PPTC7ENSG00000196850.4649.42050891.13820-0.456503.629702.70430HepG2EIF4G2
PPTC7ENSG00000196850.41598.269301310.634100.286103.287702.64140HepG2ETF1
PPTC7ENSG00000196850.4974.12250744.530100.387702.333601.62230HepG2FIP1L1
PPTC7ENSG00000196850.4478.09280866.60310-0.8581015.0297013.20650HepG2HNRNPA2B1
PPTC7ENSG00000196850.4680.89740953.35990-0.485603.870903.05660HepG2HNRNPK
PPTC7ENSG00000196850.4646.65640859.02200-0.409705.082704.19190HepG2HNRNPL
PPTC7ENSG00000196850.4935.48320738.568900.340902.028101.48070HepG2HNRNPLL
PPTC7ENSG00000196850.4486.07280688.83840-0.503005.506304.67320HepG2HNRNPU
PPTC7ENSG00000196850.4698.82550957.06010-0.453703.162102.44620HepG2IGF2BP2
PPTC7ENSG00000196850.4519.26590703.62600-0.438305.203004.22430HepG2ILF2
PPTC7ENSG00000196850.4501.32260802.99720-0.679705.162303.46240HepG2KHDRBS1
PPTC7ENSG00000196850.41444.428501045.056500.466803.635002.91250HepG2NCBP2
PPTC7ENSG00000196850.4980.55150703.210900.479502.761201.33520HepG2NKRF
PPTC7ENSG00000196850.41179.95930930.708100.342202.138201.49690HepG2PABPC4
PPTC7ENSG00000196850.4607.92660803.20000-0.401904.152203.43650HepG2PCBP1
PPTC7ENSG00000196850.4387.08560614.38920-0.666507.619306.44160HepG2PPIL4
PPTC7ENSG00000196850.41163.96380946.815300.297802.313901.69890HepG2PUM2
PPTC7ENSG00000196850.4592.47340726.32810-0.293902.467801.87730HepG2PUS1
PPTC7ENSG00000196850.41096.36400885.150300.308602.532201.93030HepG2QKI
PPTC7ENSG00000196850.41032.29090660.125600.644903.390702.61240HepG2RAVER1
PPTC7ENSG00000196850.41478.003001095.447100.432005.708605.03230HepG2RBM22
PPTC7ENSG00000196850.4617.07180847.11660-0.457105.051404.24970HepG2RECQL
PPTC7ENSG00000196850.4885.50320634.880400.479903.952002.65200HepG2RPS5
PPTC7ENSG00000196850.41052.90910717.865800.552503.051601.44730HepG2RTF1
PPTC7ENSG00000196850.4459.64280613.44220-0.416403.879403.13840HepG2SAFB2
PPTC7ENSG00000196850.4568.47640428.610600.407302.420901.53900HepG2SERBP1
PPTC7ENSG00000196850.41381.20350802.965700.782406.778705.68990HepG2SF3A3
PPTC7ENSG00000196850.4528.51020715.37900-0.436804.924804.10700HepG2SMN1
PPTC7ENSG00000196850.4473.47950672.38410-0.506002.842001.87130HepG2SMNDC1
PPTC7ENSG00000196850.4394.36010641.76030-0.702504.868002.71580HepG2SND1
PPTC7ENSG00000196850.41909.684001237.266400.6261015.5245014.59110HepG2SRFBP1
PPTC7ENSG00000196850.41908.42180888.156101.1034028.3252027.16210HepG2SRSF1
PPTC7ENSG00000196850.4891.76530722.556700.303502.873502.31370HepG2SRSF9
PPTC7ENSG00000196850.41474.530701074.238800.456807.533906.76910HepG2SSB
PPTC7ENSG00000196850.4373.64240502.95190-0.428802.412301.53100HepG2SUPT6H
PPTC7ENSG00000196850.4245.74940719.70320-1.5502015.9685014.47160HepG2TARDBP
PPTC7ENSG00000196850.4336.81440669.34210-0.9908014.4421013.45750HepG2TIAL1
PPTC7ENSG00000196850.4529.13040675.31820-0.351903.076402.48910HepG2TRIM56
PPTC7ENSG00000196850.41257.60970637.036200.9811014.7065013.21840HepG2U2AF1
PPTC7ENSG00000196850.4265.35320451.95810-0.768305.831404.71920HepG2UCHL5
PPTC7ENSG00000196850.4905.24560712.105600.346103.609602.82760HepG2UPF1
PPTC7ENSG00000196850.4466.23380700.59010-0.587502.946201.91020HepG2UPF2
PPTC7ENSG00000196850.4952.91210731.961900.380503.947002.71790HepG2UTP18
PPTC7ENSG00000196850.41209.21240687.513400.8145017.6206016.30400HepG2UTP3
PPTC7ENSG00000196850.4405.42060753.13420-0.893508.840007.55970HepG2XRN2
PPTC7ENSG00000196850.4182.04320523.45680-1.5238029.1781027.43200HepG2ZC3H8
PPTC7ENSG00000196850.41275.59900783.183000.7037017.1796016.10730HepG2ZNF622
PPTC7ENSG00000196850.41687.343301303.786600.371905.297404.55340K562AGGF1
PPTC7ENSG00000196850.42032.233201356.645400.582907.694306.55580K562AKAP8L
PPTC7ENSG00000196850.42729.536301938.776600.493405.762904.96970K562AQR
PPTC7ENSG00000196850.4565.385801048.28210-0.890708.825106.07280K562DDX51
PPTC7ENSG00000196850.41750.975901459.870400.262202.780001.90360K562DKC1
PPTC7ENSG00000196850.4853.405501164.73450-0.448704.533502.96130K562EIF2S1
PPTC7ENSG00000196850.4841.674301301.65500-0.629009.383808.17770K562EIF2S2
PPTC7ENSG00000196850.41412.456201039.692500.441903.223902.10110K562EIF3D
PPTC7ENSG00000196850.4862.556801209.88260-0.488204.656103.53620K562FIP1L1
PPTC7ENSG00000196850.41622.254601233.225900.395502.122301.51500K562G3BP2
PPTC7ENSG00000196850.4682.51770917.94270-0.427503.438102.55550K562GPKOW
PPTC7ENSG00000196850.41196.815801734.73390-0.535505.532404.46050K562GRSF1
PPTC7ENSG00000196850.41883.206701165.624600.692003.199801.85830K562HNRNPA2B1
PPTC7ENSG00000196850.4587.84120985.12450-0.744909.437808.38780K562HNRNPC
PPTC7ENSG00000196850.4590.61170879.75590-0.574905.669003.95400K562HNRNPF
PPTC7ENSG00000196850.41244.662501640.36740-0.398303.571302.67040K562HSPD1
PPTC7ENSG00000196850.42117.743401439.752600.556602.988502.12980K562KIF1C
PPTC7ENSG00000196850.4578.63180783.72990-0.437702.288301.44800K562KRR1
PPTC7ENSG00000196850.41190.898901475.16170-0.308802.640501.74020K562MATR3
PPTC7ENSG00000196850.4695.40130896.00180-0.365702.718601.85130K562METAP2
PPTC7ENSG00000196850.41950.772702478.27730-0.345302.412301.36070K562MSI2
PPTC7ENSG00000196850.4773.756901211.59250-0.647006.378505.19730K562MTPAP
PPTC7ENSG00000196850.42120.950601130.514300.907603.217902.25220K562NAA15
PPTC7ENSG00000196850.41128.435101346.14080-0.254503.068202.28570K562NSUN2
PPTC7ENSG00000196850.4727.96560961.81700-0.401903.052001.54470K562PHF6
PPTC7ENSG00000196850.41017.592201373.43200-0.432603.710102.73870K562PPIG
PPTC7ENSG00000196850.4594.44090883.27800-0.571304.808403.57100K562PSIP1
PPTC7ENSG00000196850.43743.950301345.446001.4764042.4198040.23690K562PUS1
PPTC7ENSG00000196850.42543.572701310.912900.9562027.7495025.78630K562RBM15
PPTC7ENSG00000196850.41105.418501377.24820-0.317202.380701.60630K562RBM22
PPTC7ENSG00000196850.4728.235301016.35750-0.480903.508402.36890K562RPS3
PPTC7ENSG00000196850.4663.94810966.12570-0.541103.195701.76630K562RRP9
PPTC7ENSG00000196850.4484.41000763.99320-0.657306.180704.48340K562SRFBP1
PPTC7ENSG00000196850.4705.39030981.29780-0.476302.979701.87750K562SRSF4
PPTC7ENSG00000196850.41012.988601424.81930-0.492204.613003.69370K562TARDBP
PPTC7ENSG00000196850.41084.680901374.36560-0.341503.096302.22210K562TIA1
PPTC7ENSG00000196850.4419.47100849.55950-1.0181012.1594010.08530K562TIAL1
PPTC7ENSG00000196850.41576.920101234.753800.352803.698602.76570K562U2AF2
PPTC7ENSG00000196850.4535.09620968.26640-0.855607.522705.77210K562UCHL5
PPTC7ENSG00000196850.41074.677301427.34540-0.409406.082805.06560K562UPF1
PPTC7ENSG00000196850.41581.543802183.96720-0.465605.260604.00660K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPTC7 is not available on ENCORE database.





3 RBPs can affect the splicing of PPTC7 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPTC7ENSG00000196850.4chr12-110983684110983883110977626110977750110989593110989773-0.119000.000500.00682excludedK562AQR
SEPPTC7ENSG00000196850.4chr12-110975948110976078110969119110974900110977626110977750-0.176000.000000.00000excludedK562PUS1
SEPPTC7ENSG00000196850.4chr12-110975948110976078110969119110974900110977626110977750-0.095000.000150.00635excludedK562AGGF1
A3SSPPTC7ENSG00000196850.4chr12-1109836841109839241109836841109838831109895931109898370.074000.003420.02069longerK562AQR
MXEPPTC7ENSG00000196850.4chr12-110977626110977750110983684110983883110969119110974900110989593110989773-0.228000.000000.000012includedK562PUS1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPTC7 is not avaliable on ENCORE database.