PGLS

General Information

Gene Name       : PGLS
Gene ID             : ENSG00000130313.6
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PGLS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PGLSENSG00000130313.611.5230.0120.77ENCSR000AEF
HepG2PGLSENSG00000130313.627.8915.0321.46ENCSR985KAT
K562PGLSENSG00000130313.619.6115.9117.76ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PGLS is not avaliable on ENCORE database.



Proteins bound to RNA
  • PGLS RNA is bound by 6 proteins.  







eCLIP assay for PGLS is not avaliable on ENCORE database.





6 proteins are bound to PGLS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr191763188217631938+3'-UTR,CDS4.749425.50419HepG2LARP4
chr191762816417628199+3'-UTR,CDS,intron-Proximal3.003114.97511K562YBX3
chr191762854917628656+3'-UTR,CDS,intron-Distal3.558764.14411K562METAP2
chr191762853017628584+3'-UTR,CDS,intron-Distal3.710545.73361K562YBX3
chr191763193517632017+3'-UTR6.198695.71015K562PABPC4
chr191763187717631935+3'-UTR,CDS5.252667.65809K562PABPC4
chr191763187217632022+3'-UTR,CDS4.418714.00197K562METAP2
chr191762247117622599+5'-UTR,CDS4.828668.86236K562DDX3X
chr191762264417622682+CDS3.2817613.60354K562YBX3
chr191762260417622644+CDS3.1553511.76100K562YBX3
chr191762252017622604+CDS4.467968.43072HepG2DDX3X
chr191762501217625096+intron-Distal4.103623.41738HepG2PTBP1
chr191762528817625360+intron-Distal4.289863.42734K562PTBP1
chr191762523217625305+intron-Distal3.201823.59395HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PGLS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PGLS is not available on ENCORE database.

  • 83 RBPs can affect the levels of PGLS.  








The Knockdown/knockout RNA-Seq assay for PGLS is not available on ENCORE database.





83 RBPs can affect the gene expression of PGLS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PGLSENSG00000130313.2530.62990429.003400.306602.181801.62840HepG2ACO1
PGLSENSG00000130313.2842.77150505.384400.737705.780905.04370HepG2AKAP1
PGLSENSG00000130313.2549.21840430.973600.349702.564801.82270HepG2AKAP8L
PGLSENSG00000130313.2565.78190404.691400.483302.418801.51330HepG2CCAR1
PGLSENSG00000130313.2523.85210397.263900.399002.042701.37170HepG2CIRBP
PGLSENSG00000130313.2470.38860367.225100.357102.637502.00820HepG2CELF1
PGLSENSG00000130313.2528.95260394.747600.422104.220603.33540HepG2DAZAP1
PGLSENSG00000130313.2278.51530190.087500.551002.994801.79440HepG2DDX1
PGLSENSG00000130313.2648.10680484.052000.421002.339301.75900HepG2DDX3X
PGLSENSG00000130313.2507.07660410.425900.305001.883201.30790HepG2DKC1
PGLSENSG00000130313.2376.27470186.390201.0134010.680909.37430HepG2DNAJC21
PGLSENSG00000130313.2277.03910184.751400.584404.006503.25110HepG2DNAJC2
PGLSENSG00000130313.2373.89780257.635600.537202.538501.65220HepG2EEF2
PGLSENSG00000130313.2578.14340399.723900.532301.944101.43700HepG2EIF2S1
PGLSENSG00000130313.2927.09420704.568100.395903.886903.19470HepG2ETF1
PGLSENSG00000130313.2550.66970419.164600.393602.508301.71230HepG2EWSR1
PGLSENSG00000130313.2346.58480458.37870-0.403302.234601.52060HepG2FUBP3
PGLSENSG00000130313.2355.33510224.249600.664003.536202.82110HepG2GPKOW
PGLSENSG00000130313.2260.38310409.54230-0.653406.217204.82510HepG2HDGF
PGLSENSG00000130313.2309.01820188.175900.715503.021802.34940HepG2HNRNPA1
PGLSENSG00000130313.2362.99670209.313300.794202.984902.26850HepG2HNRNPC
PGLSENSG00000130313.2286.02100418.96450-0.550702.669301.98270HepG2HNRNPK
PGLSENSG00000130313.2543.55600359.551600.596107.273106.22680HepG2HNRNPL
PGLSENSG00000130313.2306.22910214.006600.516902.311601.73040HepG2HNRNPLL
PGLSENSG00000130313.2312.85110207.929200.589304.134003.40430HepG2HNRNPU
PGLSENSG00000130313.2453.09920331.018200.452802.264701.60680HepG2IGF2BP1
PGLSENSG00000130313.2437.32220212.392401.0419015.0335013.48220HepG2ILF2
PGLSENSG00000130313.2389.56590262.254100.570802.931401.69790HepG2KHDRBS1
PGLSENSG00000130313.2495.64110392.129000.337902.529901.55230HepG2KIF1C
PGLSENSG00000130313.2262.36960371.37940-0.501302.916802.08740HepG2MSI2
PGLSENSG00000130313.2308.18050205.811400.582403.826902.84860HepG2PARN
PGLSENSG00000130313.2311.36410185.455800.747405.782204.74900HepG2PPIL4
PGLSENSG00000130313.2377.60920477.15880-0.337602.108901.61910HepG2PTBP1
PGLSENSG00000130313.2621.04480396.725100.646509.481008.52100HepG2PUM1
PGLSENSG00000130313.2358.10280516.74720-0.529104.028503.29460HepG2QKI
PGLSENSG00000130313.2271.94020468.99170-0.786306.950805.92140HepG2RBM25
PGLSENSG00000130313.2394.35380244.761600.688003.606502.39440HepG2RCC2
PGLSENSG00000130313.2332.99350185.168800.846607.804006.80250HepG2SAFB2
PGLSENSG00000130313.2325.67910472.86530-0.538002.522501.87920HepG2SF3A3
PGLSENSG00000130313.2493.07750358.384500.460204.412703.55720HepG2SLBP
PGLSENSG00000130313.2360.67260215.935800.740006.367305.45540HepG2SMN1
PGLSENSG00000130313.2331.06050217.918300.603202.971901.97560HepG2SMNDC1
PGLSENSG00000130313.2149.23550235.68650-0.659302.247601.54650HepG2SNRNP70
PGLSENSG00000130313.2282.53320518.52010-0.876009.989009.21520HepG2SRSF1
PGLSENSG00000130313.2477.11030369.008100.370602.937402.29300HepG2SRSF5
PGLSENSG00000130313.2411.72620330.254600.318002.005901.40280HepG2SRSF7
PGLSENSG00000130313.2560.58170419.627400.417704.103103.37160HepG2SUCLG1
PGLSENSG00000130313.2372.26810211.850500.813203.956603.17020HepG2SUPV3L1
PGLSENSG00000130313.2316.90240466.09240-0.556603.543402.92240HepG2TAF15
PGLSENSG00000130313.2276.22220202.033300.451102.129601.68010HepG2TIAL1
PGLSENSG00000130313.2301.10490203.848800.562703.799503.16070HepG2TRIM56
PGLSENSG00000130313.2532.43100365.138400.544103.322202.35860HepG2TUFM
PGLSENSG00000130313.2245.88760392.58700-0.675004.012003.26140HepG2U2AF1
PGLSENSG00000130313.2273.58650404.87460-0.565504.027203.32410HepG2UTP3
PGLSENSG00000130313.2380.63720208.544500.868004.837703.88820HepG2XRN2
PGLSENSG00000130313.2206.29380284.66980-0.464602.587601.93460HepG2ZC3H8
PGLSENSG00000130313.2259.71350554.07330-1.0932010.526909.49260K562AQR
PGLSENSG00000130313.2326.37890228.667700.513202.783001.72290K562CSTF2
PGLSENSG00000130313.2171.00250269.43080-0.655903.408702.39070K562EFTUD2
PGLSENSG00000130313.2707.13910414.923700.7690010.374909.11930K562EIF2S2
PGLSENSG00000130313.2184.98240288.44870-0.640903.141102.03350K562EIF3D
PGLSENSG00000130313.2404.91260220.691000.875506.554805.20960K562FIP1L1
PGLSENSG00000130313.2225.31740333.99780-0.567903.680902.99830K562FXR1
PGLSENSG00000130313.219.47400107.24050-2.4612011.489609.85090K562G3BP2
PGLSENSG00000130313.2708.34290552.868500.357402.259201.57310K562GRSF1
PGLSENSG00000130313.2531.72340299.208900.829407.344406.06510K562HSPD1
PGLSENSG00000130313.2189.16230338.78380-0.840706.304404.09080K562LARP7
PGLSENSG00000130313.279.27490179.98490-1.182902.711901.74250K562PCBP2
PGLSENSG00000130313.2436.39530250.529100.800605.913004.63890K562PPIG
PGLSENSG00000130313.2146.59070262.18790-0.838804.556003.59380K562PRPF8
PGLSENSG00000130313.2483.19470652.96250-0.434402.370301.85910K562PUS1
PGLSENSG00000130313.244.66490102.31690-1.195803.069401.56640K562RAVER1
PGLSENSG00000130313.2518.67580636.21280-0.294701.822301.32310K562RBM15
PGLSENSG00000130313.2162.53740266.28080-0.712203.786802.07700K562SDAD1
PGLSENSG00000130313.2374.54330492.95060-0.396302.842602.01880K562SF3A3
PGLSENSG00000130313.2195.28420408.37270-1.064302.981101.68940K562SNRNP200
PGLSENSG00000130313.2381.54220505.04230-0.404603.070402.08890K562SRPK2
PGLSENSG00000130313.2250.58290160.910200.638902.929501.83700K562SRSF4
PGLSENSG00000130313.2318.65940182.142700.806802.233401.31040K562SRSF5
PGLSENSG00000130313.2234.03800328.98740-0.491302.941501.37260K562SRSF9
PGLSENSG00000130313.2375.83140195.034300.946303.936303.08520K562TARDBP
PGLSENSG00000130313.2399.44110188.150701.086006.476305.14590K562TIA1
PGLSENSG00000130313.2292.87990184.794900.664302.715801.63610K562TRA2A
PGLSENSG00000130313.249.96120103.93330-1.056803.455402.20570K562U2AF1
PGLSENSG00000130313.243.03540107.34620-1.318705.575204.43570K562U2AF2
PGLSENSG00000130313.2284.99990471.31500-0.725708.083506.70690K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PGLS is not available on ENCORE database.





8 RBPs can affect the splicing of PGLS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPGLSENSG00000130313.2chr19+1762717917627283176269811762708917628096176281980.086000.000000.00025includedHepG2HNRNPK
SEPGLSENSG00000130313.2chr19+1762717917627283176269811762708917628096176281980.052000.002780.03295includedHepG2U2AF2
SEPGLSENSG00000130313.2chr19+1762717917627283176269811762708917628096176281980.061000.000010.00475includedK562MTPAP
SEPGLSENSG00000130313.2chr19+1762717917627283176269811762708917628096176281980.067000.000000.00074includedK562NSUN2
SEPGLSENSG00000130313.2chr19+1762717917627283176269811762708917628096176281980.055000.000180.00782includedHepG2SF3A3
SEPGLSENSG00000130313.2chr19+1762717917627283176269811762708917628096176281980.070000.000000.00001includedK562HNRNPUL1
SEPGLSENSG00000130313.2chr19+1762851817628639176280961762819817631752176318520.063000.001880.09923includedK562HNRNPUL1
SEPGLSENSG00000130313.2chr19+1762717917627283176269811762708917628096176281980.055000.000010.00342includedK562UPF1
SEPGLSENSG00000130313.2chr19+1762717917627283176269811762708917628096176281980.157000.005040.07301includedK562U2AF2
MXEPGLSENSG00000130313.2chr19+17628096176281981762851817628659176269811762708917631752176320970.235000.003500.037261includedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PGLS is not avaliable on ENCORE database.