PARP4

General Information

Gene Name       : PARP4
Gene ID             : ENSG00000102699.5
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PARP4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PARP4ENSG00000102699.535.5835.7835.68ENCSR000AEF
HepG2PARP4ENSG00000102699.522.0633.0327.55ENCSR985KAT
K562PARP4ENSG00000102699.513.3214.3913.86ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PARP4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PARP4 RNA is bound by 24 proteins.  







eCLIP assay for PARP4 is not avaliable on ENCORE database.





24 proteins are bound to PARP4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr132508684325086864-5'-UTR,intron-Distal3.351883.66187K562ZNF622
chr132508681725086892-5'-UTR,intron-Distal3.953563.53067K562SRSF1
chr132508683525086853-5'-UTR,intron-Distal3.434844.57766HepG2SRSF1
chr132508683525086925-5'-UTR,intron-Distal3.629844.02244HepG2NCBP2
chr132506871025068750-CDS,intron-Distal,intron-Proximal5.0234018.25084HepG2BCLAF1
chr132507573625075805-CDS,intron-Distal,intron-Proximal4.091498.96944HepG2PRPF8
chr132500882825008888-CDS,intron-Distal3.108573.23702K562PTBP1
chr132507446625074517-CDS,intron-Distal3.814884.79276K562ZNF622
chr132507234025072413-CDS,intron-Distal,intron-Proximal3.521563.84691HepG2SF3B4
chr132506875025068795-CDS,intron-Distal4.5106119.98514HepG2BCLAF1
chr132500854325008578-CDS,intron-Distal3.217413.34848HepG2PPIG
chr132505235825052414-CDS,intron-Distal3.105135.93420HepG2GRWD1
chr132507445425074517-CDS,intron-Distal3.752668.10600HepG2PPIG
chr132506041825060443-CDS,intron-Distal4.455878.15024HepG2BCLAF1
chr132507445725074509-CDS,intron-Distal3.847676.23335HepG2GRWD1
chr132505879025058826-CDS,intron-Distal,intron-Proximal4.2543715.57891HepG2BCLAF1
chr132502649725026567-CDS,intron-Distal,intron-Proximal4.3542211.50355HepG2PRPF8
chr132502909125029167-CDS,intron-Distal,intron-Proximal3.489795.72015K562TIA1
chr132506774525067756-CDS,intron-Distal4.165306.23296HepG2BCLAF1
chr132504411225044173-CDS,intron-Distal,intron-Proximal3.540373.95921HepG2U2AF2
chr132506775625067821-CDS,intron-Distal3.5148619.03343HepG2BCLAF1
chr132507447325074508-CDS,intron-Distal3.685629.83277HepG2BCLAF1
chr132506666525066730-CDS,intron-Distal4.173998.02029HepG2GRWD1
chr132506871125068769-CDS,intron-Distal3.878118.70187K562ZNF622
chr132506870925068808-CDS,intron-Distal,intron-Proximal3.3395310.25938HepG2ZNF800
chr132505879125058806-CDS,intron-Distal5.093163.59565K562DDX24
chr132507576925075819-CDS,intron-Distal,intron-Proximal3.343605.21025HepG2PPIG
chr132506871325068834-CDS,intron-Distal3.094816.05977K562UCHL5
chr132500956025009620-CDS,intron-Distal,intron-Proximal3.185135.12776HepG2U2AF2
chr132506781625067871-CDS,intron-Distal3.167215.80393HepG2ZNF800
chr132507228825072368-CDS,intron-Distal,intron-Proximal3.396866.92518HepG2PPIG
chr132505235825052414-CDS,intron-Distal4.0643920.44190HepG2BCLAF1
chr132506775225067804-CDS,intron-Distal3.038255.66280HepG2GRWD1
chr132506782625067869-CDS,intron-Distal3.203124.99842HepG2PPIG
chr132503060025030616-CDS,intron-Distal4.130778.08603HepG2BCLAF1
chr132506782925067867-CDS,intron-Distal3.504534.42924HepG2HLTF
chr132502910525029170-CDS,intron-Distal,intron-Proximal4.8912210.09745HepG2PRPF8
chr132506874125068798-CDS,intron-Distal3.935466.39364HepG2PPIG
chr132506480425064840-CDS,intron-Distal,intron-Proximal3.5154712.01276HepG2BCLAF1
chr132506033625060373-CDS,intron-Distal4.3990511.99763HepG2BCLAF1
chr132502082125020853-CDS,intron-Distal3.159533.00343HepG2GRWD1
chr132504963925049712-CDS,intron-Distal3.479644.69540HepG2IGF2BP1
chr132506775525067811-CDS,intron-Distal4.245884.38566HepG2LIN28B
chr132505878925058818-CDS,intron-Distal,intron-Proximal3.343575.18255HepG2HLTF
chr132506872225068795-CDS,intron-Distal4.0081210.69434HepG2GRWD1
chr132507788825077914-CDS,intron-Distal3.607364.79276K562ZNF622
chr132506656325066630-CDS,intron-Distal3.176647.88565HepG2GRWD1
chr132503318425033212-CDS,intron-Distal3.9663210.35753HepG2BCLAF1
chr132507230725072354-CDS,intron-Distal3.563204.71371HepG2GRWD1
chr132506659325066641-CDS,intron-Distal3.8644213.63776HepG2BCLAF1
chr132500853525008598-CDS,intron-Distal4.352103.71613K562UCHL5
chr132503590625035955-intron-Distal4.454635.58061HepG2SUGP2
chr132503746825037506-intron-Distal3.022843.10640HepG2SUGP2
chr132503713225037186-intron-Distal3.920215.06177HepG2SUGP2
chr132508156725081618-intron-Distal3.929113.19526HepG2CSTF2T
chr132502553125025638-intron-Distal3.383094.52780K562HNRNPK
chr132503688625036965-intron-Distal4.006986.77642HepG2SUGP2
chr132503604825036093-intron-Distal4.174444.05620HepG2MATR3
chr132508200125082065-intron-Distal4.560045.18111K562CSTF2T
chr132503659825036655-intron-Distal4.957217.65425HepG2SUGP2
chr132508197125082074-intron-Distal5.018148.80407HepG2CSTF2
chr132504000425040107-intron-Distal3.803276.35227HepG2HNRNPL
chr132503609125036143-intron-Distal4.516544.78128HepG2SUGP2
chr132508200825082069-intron-Distal4.995178.87911K562FMR1
chr132503683325036886-intron-Distal3.101975.12506HepG2SUGP2
chr132503642725036503-intron-Distal4.2861614.27839HepG2SUGP2
chr132503651425036571-intron-Distal3.601977.51551HepG2SUGP2
chr132503637525036427-intron-Distal4.789787.34531HepG2SUGP2
chr132503651525036598-intron-Distal4.892617.15419HepG2MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PARP4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PARP4 is not available on ENCORE database.

  • 78 RBPs can affect the levels of PARP4.  








The Knockdown/knockout RNA-Seq assay for PARP4 is not available on ENCORE database.





78 RBPs can affect the gene expression of PARP4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PARP4ENSG00000102699.53314.626202567.692000.368307.919006.99810HepG2ACO1
PARP4ENSG00000102699.54234.527503289.488300.364202.586002.07060HepG2AKAP1
PARP4ENSG00000102699.53056.371202579.801700.244503.289702.46110HepG2AKAP8L
PARP4ENSG00000102699.53552.727803102.337000.195502.336601.69640HepG2AUH
PARP4ENSG00000102699.52958.116902201.713400.426005.954304.88070HepG2CALR
PARP4ENSG00000102699.52484.340103520.48210-0.502903.851002.68700HepG2CCAR1
PARP4ENSG00000102699.52144.437003154.30600-0.556703.509702.64190HepG2CNOT7
PARP4ENSG00000102699.52661.784401993.947200.416703.944303.13660HepG2CPSF6
PARP4ENSG00000102699.52625.213101961.780300.420203.177102.35670HepG2DDX55
PARP4ENSG00000102699.52162.511202456.59970-0.184001.914601.33530HepG2DKC1
PARP4ENSG00000102699.51708.068702140.90510-0.325905.987905.08150HepG2DNAJC2
PARP4ENSG00000102699.52594.009502108.532000.298802.729901.59240HepG2FASTKD2
PARP4ENSG00000102699.52120.604201738.789400.286302.414901.67950HepG2FUBP3
PARP4ENSG00000102699.51538.627802778.34710-0.852608.459406.61770HepG2FUS
PARP4ENSG00000102699.52157.331902901.42470-0.427503.846203.04060HepG2FXR1
PARP4ENSG00000102699.52106.739802920.04300-0.471002.922601.77900HepG2GRSF1
PARP4ENSG00000102699.52376.939102757.26230-0.214103.516802.76390HepG2HNRNPL
PARP4ENSG00000102699.53051.735102156.984500.500505.396404.54790HepG2HNRNPLL
PARP4ENSG00000102699.51628.042002021.74410-0.312502.842601.87930HepG2HNRNPM
PARP4ENSG00000102699.53418.388702735.891400.321202.445701.80600HepG2IGF2BP2
PARP4ENSG00000102699.51963.327402902.43730-0.564005.932504.98310HepG2MAGOH
PARP4ENSG00000102699.52274.607202918.69180-0.359702.515201.91090HepG2MATR3
PARP4ENSG00000102699.52146.831102987.45130-0.476704.309203.52500HepG2NCBP2
PARP4ENSG00000102699.52014.336402385.01330-0.243702.999202.12120HepG2PARN
PARP4ENSG00000102699.51755.740702149.10960-0.291703.401802.59150HepG2PPIL4
PARP4ENSG00000102699.52009.011201513.369700.408603.370302.48680HepG2PRPF8
PARP4ENSG00000102699.52260.831902865.01510-0.341703.578002.91190HepG2PUF60
PARP4ENSG00000102699.53384.805602860.160000.242902.620102.00910HepG2QKI
PARP4ENSG00000102699.54381.823502538.428200.787505.303404.34460HepG2RAVER1
PARP4ENSG00000102699.54218.161503236.898700.381905.690004.51640HepG2RBM15
PARP4ENSG00000102699.54466.544102977.005000.5852014.9260013.91770HepG2RBM22
PARP4ENSG00000102699.53607.360302595.802500.474706.829305.81030HepG2RBM25
PARP4ENSG00000102699.51659.832002427.53160-0.548505.830604.38030HepG2RBM27
PARP4ENSG00000102699.52568.526502939.10780-0.194402.171901.68070HepG2NELFE
PARP4ENSG00000102699.52244.438002737.42340-0.286504.189403.45200HepG2RECQL
PARP4ENSG00000102699.52284.153303167.77950-0.471803.246902.38210HepG2RPS3A
PARP4ENSG00000102699.52370.414501497.037300.662907.045305.85660HepG2RRP9
PARP4ENSG00000102699.52337.715003163.45330-0.436403.054602.34600HepG2SF3A3
PARP4ENSG00000102699.51945.218102502.34430-0.363308.113107.10210HepG2SMN1
PARP4ENSG00000102699.54385.832903362.466200.383209.457508.68240HepG2SRFBP1
PARP4ENSG00000102699.53307.394402828.702500.225502.839702.20570HepG2SRSF5
PARP4ENSG00000102699.53305.217202334.859600.5013011.0610010.08660HepG2SRSF9
PARP4ENSG00000102699.52565.045602919.50150-0.186702.104701.64150HepG2SSB
PARP4ENSG00000102699.52436.994803217.08470-0.4007010.096709.03230HepG2SUCLG1
PARP4ENSG00000102699.53088.132101952.926300.661007.443506.42120HepG2SUPV3L1
PARP4ENSG00000102699.52095.943903812.18070-0.863004.860903.47690HepG2TBRG4
PARP4ENSG00000102699.52841.092502370.297500.261302.492901.69650HepG2TIA1
PARP4ENSG00000102699.51909.076202341.27510-0.294403.014202.49570HepG2TIAL1
PARP4ENSG00000102699.51866.678102362.24400-0.339705.475804.73400HepG2TRIM56
PARP4ENSG00000102699.53492.729202506.623900.478505.473704.60770HepG2U2AF1
PARP4ENSG00000102699.51092.910401788.29370-0.710405.517304.07090HepG2UPF2
PARP4ENSG00000102699.51958.738702708.60180-0.4676010.480909.43450HepG2UTP3
PARP4ENSG00000102699.51368.453301922.44170-0.490404.434803.52390HepG2XRN2
PARP4ENSG00000102699.52610.082602209.587600.240203.698802.94120HepG2ZC3H8
PARP4ENSG00000102699.54161.411803085.513600.4315013.8611012.87090HepG2ZNF622
PARP4ENSG00000102699.51195.340701554.98460-0.379505.277504.53470K562AGGF1
PARP4ENSG00000102699.51214.951401618.01560-0.413304.005603.21750K562AKAP8L
PARP4ENSG00000102699.51321.710901684.65840-0.350002.713302.12970K562AQR
PARP4ENSG00000102699.51416.137801697.65700-0.261602.572501.69380K562ATP5C1
PARP4ENSG00000102699.51448.558101858.34490-0.359404.016102.55730K562CCDC124
PARP4ENSG00000102699.51939.594101389.167000.481402.466301.47340K562CNOT7
PARP4ENSG00000102699.51250.342601018.026100.296402.404801.66870K562CPSF6
PARP4ENSG00000102699.5620.24880786.23660-0.342102.590801.57250K562CSTF2
PARP4ENSG00000102699.5733.31970908.66690-0.309302.921201.55970K562DDX27
PARP4ENSG00000102699.5725.00420938.80600-0.372803.051901.95520K562DDX3X
PARP4ENSG00000102699.52030.771701778.434100.191301.863301.30890K562DDX47
PARP4ENSG00000102699.51492.861701741.20310-0.222002.143701.38400K562DKC1
PARP4ENSG00000102699.51658.227701321.347400.327503.859603.03230K562EIF2S2
PARP4ENSG00000102699.5962.026501269.56770-0.400203.334602.39700K562FIP1L1
PARP4ENSG00000102699.5651.45160914.19010-0.488805.072403.19410K562FUS
PARP4ENSG00000102699.51266.463601760.80040-0.475405.524504.45340K562GRSF1
PARP4ENSG00000102699.5624.866301044.25260-0.740907.203505.58850K562HNRNPM
PARP4ENSG00000102699.51621.922501272.955500.349403.925402.85620K562HNRNPU
PARP4ENSG00000102699.51307.474001721.24320-0.396703.482602.59230K562HSPD1
PARP4ENSG00000102699.5889.289501233.79570-0.472403.242102.09890K562IGF2BP2
PARP4ENSG00000102699.51048.905301296.73450-0.306002.365701.58550K562MAGOH
PARP4ENSG00000102699.51319.557101643.71370-0.316902.470101.47340K562MAK16
PARP4ENSG00000102699.51553.209901923.66310-0.308602.908701.97050K562MBNL1
PARP4ENSG00000102699.51013.198701267.52410-0.323102.813001.45220K562PCBP1
PARP4ENSG00000102699.51902.224401355.183900.489104.272503.23760K562PCBP3
PARP4ENSG00000102699.51423.576401039.506900.453505.107704.01690K562POLR2G
PARP4ENSG00000102699.5999.002601441.23220-0.528705.329504.13000K562PPIG
PARP4ENSG00000102699.51027.875501259.85400-0.293602.391701.76680K562PTBP1
PARP4ENSG00000102699.53101.043702504.860700.307902.774401.95720K562PUF60
PARP4ENSG00000102699.51225.777101604.74450-0.388603.199802.62310K562PUS1
PARP4ENSG00000102699.51227.149401563.48480-0.349503.883003.19720K562RBM15
PARP4ENSG00000102699.5937.134701208.08440-0.366402.912802.04630K562RBM22
PARP4ENSG00000102699.5820.671101064.74070-0.375603.529002.55960K562SF3B4
PARP4ENSG00000102699.5671.443201235.06980-0.8793014.5426012.91840K562SRSF1
PARP4ENSG00000102699.5937.212601166.41270-0.315602.271101.33670K562SRSF5
PARP4ENSG00000102699.51699.219302185.51840-0.363104.308602.46470K562SUCLG1
PARP4ENSG00000102699.5986.900401205.74930-0.289002.239301.51010K562TIA1
PARP4ENSG00000102699.5912.901001183.16210-0.374102.869201.75180K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PARP4 is not available on ENCORE database.





6 RBPs can affect the splicing of PARP4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPARP4ENSG00000102699.5chr13-2500671825006834250055142500561425008532250096120.077000.000000.00019includedHepG2G3BP1
SEPARP4ENSG00000102699.5chr13-250094402500961225008532250087192501598325016106-0.320000.001330.02648excludedK562SRSF1
SEPARP4ENSG00000102699.5chr13-2500671825006834250055142500561425008532250096120.282000.000000.00000includedHepG2U2AF2
SEPARP4ENSG00000102699.5chr13-2500671825006834250055142500561425008532250096120.121000.002720.05116includedK562U2AF1
SEPARP4ENSG00000102699.5chr13-2500671825006834250055142500561425008532250096120.280000.000000.00000includedK562U2AF2
SEPARP4ENSG00000102699.5chr13-2500671825006834250055142500561425008532250096120.191000.000000.00006includedHepG2FUS
A3SSPARP4ENSG00000102699.5chr13-250085322500961225008532250087192501598325016106-0.213000.000210.02268shorterK562SRSF1
RIPARP4ENSG00000102699.5chr13-250085322500961225008532250087192500944025009612-0.063000.008800.04806excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PARP4 is not avaliable on ENCORE database.