MTOR

General Information

Gene Name       : MTOR
Gene ID             : ENSG00000198793.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MTOR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MTORENSG00000198793.1220.5821.9121.24ENCSR000AEF
HepG2MTORENSG00000198793.1226.3223.3524.84ENCSR985KAT
K562MTORENSG00000198793.1242.3043.7243.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MTOR is not avaliable on ENCORE database.



Proteins bound to RNA
  • MTOR RNA is bound by 21 proteins.  







eCLIP assay for MTOR is not avaliable on ENCORE database.





21 proteins are bound to MTOR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11116733011167434-3'-UTR,intron-Distal,intron-Proximal4.8100919.70107K562PUM2
chr11119131311191404-5'-UTR,intron-Distal5.469799.16480HepG2RBFOX2
chr11119079811190869-5'-UTR,CDS,intron-Distal,intron-Proximal3.986074.15711K562AQR
chr11119119311191273-5'-UTR,intron-Distal3.489644.74917HepG2PCBP2
chr11132249811322563-5'-UTR,intron-Distal3.960907.13336HepG2NCBP2
chr11132250011322566-5'-UTR,intron-Distal,intron-Proximal4.978248.88833HepG2DDX3X
chr11132243011322513-5'-UTR,intron-Distal4.734824.86944K562AQR
chr11121018711210232-CDS,intron-Distal3.858275.89622K562FXR2
chr11130160811301649-CDS,intron-Distal,intron-Proximal4.486684.86776HepG2LIN28B
chr11131389811313981-CDS,intron-Distal3.383956.92192K562UCHL5
chr11129345411293526-CDS,intron-Distal,intron-Proximal5.105656.58593HepG2BCLAF1
chr11127089811270957-CDS,intron-Distal3.559254.19763K562DDX24
chr11119311411193139-CDS,intron-Distal,intron-Proximal3.566317.16774K562AQR
chr11118801511188069-CDS,intron-Distal,intron-Proximal4.3420911.57027HepG2PRPF8
chr11127093611270961-CDS,intron-Distal3.364344.74241K562YBX3
chr11121018911210233-CDS,intron-Distal5.107735.34688K562DDX24
chr11117445211174505-CDS,intron-Distal4.224263.83824K562BUD13
chr11121018211210225-CDS,intron-Distal,intron-Proximal4.547473.81516HepG2EIF3H
chr11129249311292549-CDS,intron-Distal4.160183.66349K562LIN28B
chr11129806511298102-CDS,intron-Distal4.104863.29312HepG2FXR2
chr11120502611205062-CDS,intron-Distal3.913103.43253K562YBX3
chr11129249611292557-CDS,intron-Distal4.165413.23259HepG2LIN28B
chr11129146411291492-CDS,intron-Distal,intron-Proximal3.759395.56491HepG2BCLAF1
chr11119938511199469-CDS,intron-Distal3.292818.67981K562YBX3
chr11129100511291058-CDS,intron-Distal3.670704.93097K562YBX3
chr11118771911187756-CDS,intron-Distal4.681455.42280K562FXR2
chr11131396311314007-CDS,intron-Distal3.080343.71797HepG2BCLAF1
chr11130160811301658-CDS,intron-Distal,intron-Proximal3.382144.30200K562LIN28B
chr11131608711316152-CDS,intron-Distal3.333625.44868K562ZNF622
chr11118781811187848-CDS,intron-Distal3.370154.41130K562AQR
chr11130809911308167-CDS,intron-Distal,intron-Proximal4.282514.28193HepG2AQR
chr11130787511307913-CDS,intron-Distal,intron-Proximal3.660684.96634HepG2PPIG
chr11127624011276296-CDS,intron-Distal,intron-Proximal3.552154.44431K562BUD13
chr11131862711318646-CDS,intron-Distal3.6637911.37584K562YBX3
chr11121721711217273-CDS,intron-Distal4.993416.56513K562FXR2
chr11127240711272531-CDS,intron-Distal3.336286.77101K562FMR1
chr11131864611318650-CDS,intron-Distal4.5740613.15557K562YBX3
chr11118782811187906-CDS,intron-Distal,intron-Proximal3.715044.57180HepG2AQR
chr11131389711313936-CDS,intron-Distal4.711685.23082K562DDX24
chr11129143411291500-CDS,intron-Distal,intron-Proximal4.874885.69951K562AQR
chr11121018811210226-CDS,intron-Distal3.098404.33023K562ZNF622
chr11126936411269457-CDS,intron-Distal,intron-Proximal3.097325.97777HepG2PPIG
chr11131931311319325-CDS,intron-Distal3.736519.98187K562YBX3
chr11121720811217307-CDS,intron-Distal,intron-Proximal3.186194.04703HepG2FXR2
chr11130777411307788-CDS,intron-Distal,intron-Proximal4.176663.02457HepG2BCLAF1
chr11118783411187904-CDS,intron-Distal,intron-Proximal4.8729612.43500HepG2PRPF8
chr11126931511269379-CDS,intron-Distal,intron-Proximal4.065706.79537K562AQR
chr11126466411264704-CDS,intron-Distal4.102418.34773K562YBX3
chr11118126411181320-CDS,intron-Distal,intron-Proximal4.878236.59451HepG2PRPF8
chr11126461811264728-CDS,intron-Distal3.241375.08826HepG2FXR2
chr11117706011177132-CDS,intron-Distal,intron-Proximal4.526084.34615K562LIN28B
chr11131387411313900-CDS,intron-Distal,intron-Proximal3.187823.90373HepG2AQR
chr11129249011292536-CDS,intron-Distal,intron-Proximal4.241304.93978HepG2BCLAF1
chr11131934511319405-CDS,intron-Distal5.138764.77840HepG2EIF3H
chr11119067211190729-CDS,intron-Distal3.279385.74118K562YBX3
chr11131610411316166-CDS,intron-Distal4.738384.59551K562FXR2
chr11129145211291491-CDS,intron-Distal3.308413.64266HepG2PPIG
chr11118801311188063-CDS,intron-Distal,intron-Proximal3.715484.28285K562AQR
chr11128875011288836-CDS,intron-Distal3.890317.12716HepG2EIF3H
chr11131931611319387-CDS,intron-Distal3.602886.36847HepG2BCLAF1
chr11117482611174880-CDS,intron-Distal,intron-Proximal4.933745.35117HepG2PRPF8
chr11130768211307723-CDS,intron-Distal5.056187.22868K562FXR2
chr11127620411276282-CDS,intron-Distal,intron-Proximal3.849629.20662K562DDX24
chr11130788511308011-CDS,intron-Distal,intron-Proximal5.182796.29060HepG2EIF3H
chr11126462911264664-CDS,intron-Distal4.184048.99212K562YBX3
chr11131930411319313-CDS,intron-Distal,intron-Proximal4.2915310.31015K562YBX3
chr11129249211292531-CDS,intron-Distal,intron-Proximal4.515525.23082K562DDX24
chr11127285611272892-CDS,intron-Distal4.419195.23082K562DDX24
chr11118199211182050-CDS,intron-Distal,intron-Proximal4.384434.53454K562PRPF8
chr11127623911276283-CDS,intron-Distal3.426083.31745K562ZNF622
chr11118804411188070-CDS,intron-Distal,intron-Proximal3.067313.90373HepG2AQR
chr11121727811217349-CDS,intron-Distal,intron-Proximal4.578129.89724K562FXR2
chr11118784811187901-CDS,intron-Distal,intron-Proximal4.3803610.81562K562AQR
chr11129145411291493-CDS,intron-Distal,intron-Proximal4.419195.64870K562DDX24
chr11118795111187994-intron-Distal,intron-Proximal4.619064.68690HepG2PRPF8
chr11127335411273456-intron-Distal,intron-Proximal4.729449.85896K562AQR
chr11131389111313896-intron-Distal,intron-Proximal4.9090412.09955HepG2PRPF8
chr11131388011313896-intron-Distal,intron-Proximal4.346024.15711K562AQR
chr11119301811193088-intron-Distal,intron-Proximal4.653073.32531K562AQR
chr11131896911319045-intron-Distal4.442174.22101K562PRPF8
chr11125751111257600-intron-Distal3.505214.79863K562TARDBP
chr11119308811193114-intron-Distal,intron-Proximal5.676739.95272K562AQR
chr11126555911265620-intron-Distal4.148714.17759HepG2QKI
chr11131385111313891-intron-Distal,intron-Proximal6.0050813.87810HepG2PRPF8
chr11131384711313880-intron-Distal,intron-Proximal4.486075.26367K562AQR
chr11119326311193319-intron-Distal,intron-Proximal4.930434.90235K562SF3B4
chr11118795811188013-intron-Distal,intron-Proximal3.888893.79442K562AQR
chr11117282211172909-intron-Distal,intron-Proximal3.916114.98250K562AQR
chr11129411811294200-intron-Distal,intron-Proximal4.892345.17615K562AQR
chr11119325511193320-intron-Distal,intron-Proximal3.192913.33980HepG2SF3B4
chr11118802911188044-intron-Distal,intron-Proximal4.502794.97857HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MTOR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MTOR is not available on ENCORE database.

  • 89 RBPs can affect the levels of MTOR.  








The Knockdown/knockout RNA-Seq assay for MTOR is not available on ENCORE database.





89 RBPs can affect the gene expression of MTOR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MTORENSG00000198793.82898.501402304.355100.330802.373901.50050HepG2ABCF1
MTORENSG00000198793.83406.019702206.951900.625906.321405.55440HepG2AKAP1
MTORENSG00000198793.82909.754302201.331800.402407.646706.44670HepG2AKAP8L
MTORENSG00000198793.82612.826301885.115800.470905.379704.57940HepG2BOP1
MTORENSG00000198793.81145.202201512.49290-0.401304.574003.61210HepG2CALR
MTORENSG00000198793.82192.206001734.866800.337502.513501.77170HepG2CIRBP
MTORENSG00000198793.82440.836301827.573300.417302.080101.42150HepG2CNOT7
MTORENSG00000198793.82412.359502084.772100.210502.081801.51070HepG2CELF1
MTORENSG00000198793.82610.241102241.251900.219803.047002.27520HepG2DAZAP1
MTORENSG00000198793.81975.700901563.883400.337102.947702.25000HepG2DDX21
MTORENSG00000198793.81826.805301347.400500.439003.785902.72070HepG2EEF2
MTORENSG00000198793.81085.267701440.05480-0.408102.506801.46020HepG2AGO1
MTORENSG00000198793.82614.007601929.160800.438203.381802.67680HepG2EIF4A3
MTORENSG00000198793.82838.270401878.478700.595304.639703.76270HepG2EIF4B
MTORENSG00000198793.83010.179102211.468500.4447010.059308.65720HepG2EIF4G1
MTORENSG00000198793.82037.500101490.292400.451105.150103.66260HepG2FASTKD2
MTORENSG00000198793.82564.546001805.718900.506004.600403.75130HepG2G3BP1
MTORENSG00000198793.81772.029402091.79250-0.239302.878701.88390HepG2HDGF
MTORENSG00000198793.82046.951201638.771600.320802.709002.02250HepG2HNRNPC
MTORENSG00000198793.81747.775502041.49070-0.224102.179401.57130HepG2HNRNPL
MTORENSG00000198793.82409.728801872.103900.364102.901202.25870HepG2HNRNPLL
MTORENSG00000198793.81758.282202870.36780-0.707107.161905.23200HepG2HSPD1
MTORENSG00000198793.82903.239602376.876200.288502.803502.07460HepG2IGF2BP1
MTORENSG00000198793.83719.148201835.423401.0188019.0225017.43100HepG2IGF2BP2
MTORENSG00000198793.82670.418201722.668700.632302.432001.51790HepG2IGF2BP3
MTORENSG00000198793.81739.864102002.86760-0.203102.573101.58850HepG2KIF1C
MTORENSG00000198793.81245.803101581.26390-0.344002.955701.69970HepG2NAA15
MTORENSG00000198793.83686.907702720.180900.438602.766801.33740HepG2NKRF
MTORENSG00000198793.81731.939102222.44160-0.359803.744202.85430HepG2NOL12
MTORENSG00000198793.83244.033901784.832000.8619012.9292011.39850HepG2PABPC4
MTORENSG00000198793.81175.620601451.99460-0.304603.187602.40140HepG2PPIL4
MTORENSG00000198793.83039.723002252.323100.432409.075708.13310HepG2PUM1
MTORENSG00000198793.82874.857102250.599300.353104.819803.94720HepG2PUM2
MTORENSG00000198793.83011.127002151.409500.484908.297007.30290HepG2QKI
MTORENSG00000198793.82780.931701952.553900.510107.308206.25640HepG2RBM25
MTORENSG00000198793.83005.229901636.707000.876608.189006.63690HepG2RPS10
MTORENSG00000198793.81400.284501064.309200.395703.730203.02760HepG2RPS19
MTORENSG00000198793.81625.806001068.123100.606006.629205.18680HepG2SERBP1
MTORENSG00000198793.83466.978503132.270800.146401.766201.33820HepG2SRFBP1
MTORENSG00000198793.8914.300301646.65060-0.8488010.950508.11850HepG2SRP68
MTORENSG00000198793.83151.298402158.751200.5456014.8575013.94830HepG2SRSF1
MTORENSG00000198793.81544.394001993.92260-0.368602.200301.31940HepG2SRSF3
MTORENSG00000198793.82749.450402094.945400.392108.023607.02930HepG2SRSF5
MTORENSG00000198793.83287.712202371.511700.4712010.101408.91700HepG2SRSF7
MTORENSG00000198793.82354.814902719.55380-0.207802.558602.06020HepG2SSB
MTORENSG00000198793.82156.994401721.067200.325601.890501.31730HepG2SUPV3L1
MTORENSG00000198793.82339.904201940.398600.270003.127402.53630HepG2TAF15
MTORENSG00000198793.81475.816801782.93130-0.272702.431401.64610HepG2TIA1
MTORENSG00000198793.83489.539702194.312900.669208.547607.04820HepG2UBE2L3
MTORENSG00000198793.81127.946501575.80840-0.482402.940601.90580HepG2UPF2
MTORENSG00000198793.81930.164902390.93840-0.308904.607903.86710HepG2UTP3
MTORENSG00000198793.81201.646501694.20380-0.495604.705303.76860HepG2XRN2
MTORENSG00000198793.83789.842001919.801800.9811024.9050023.25420HepG2ZC3H8
MTORENSG00000198793.84518.158702723.647000.7301037.6966036.28080HepG2ZNF622
MTORENSG00000198793.83022.373103959.87390-0.389808.567707.64210K562AGGF1
MTORENSG00000198793.83917.103705631.51020-0.523707.693906.79620K562AQR
MTORENSG00000198793.83376.900503964.49750-0.231402.809801.48640K562BCCIP
MTORENSG00000198793.82293.707002909.93490-0.343303.939903.00480K562CPSF6
MTORENSG00000198793.82317.130302906.39580-0.326904.225302.88420K562CSTF2
MTORENSG00000198793.87100.400405667.635100.325106.346205.41730K562DDX47
MTORENSG00000198793.82199.000904109.44070-0.9021014.8514011.51730K562DDX51
MTORENSG00000198793.82864.970703804.52270-0.409204.132002.99830K562EFTUD2
MTORENSG00000198793.84075.173405457.65580-0.421408.666507.50070K562EIF2S2
MTORENSG00000198793.83711.271902324.046500.6752017.0708015.02420K562EIF3G
MTORENSG00000198793.83558.713104359.73730-0.292902.587901.76920K562FIP1L1
MTORENSG00000198793.82438.626302961.07770-0.280102.233601.46320K562FMR1
MTORENSG00000198793.81922.962602509.90550-0.384303.155502.17430K562FTO
MTORENSG00000198793.84214.357103184.458800.404207.729506.78620K562FXR1
MTORENSG00000198793.81738.538102323.27720-0.418302.716302.01750K562G3BP2
MTORENSG00000198793.84624.560107272.85240-0.6532013.2848011.60760K562GRSF1
MTORENSG00000198793.82776.262703586.09500-0.369302.851901.90560K562HNRNPM
MTORENSG00000198793.84587.215005309.81020-0.211002.275101.46390K562HNRNPU
MTORENSG00000198793.82784.280405910.66960-1.0860026.5859024.38940K562HSPD1
MTORENSG00000198793.81799.076802372.50790-0.399202.555101.66190K562KRR1
MTORENSG00000198793.84161.769804898.81340-0.235202.249801.44400K562MBNL1
MTORENSG00000198793.82873.181603749.17350-0.383903.326201.88260K562NONO
MTORENSG00000198793.82451.667002956.22780-0.270002.191801.32610K562PCBP2
MTORENSG00000198793.84339.257905395.92500-0.314402.412701.63680K562PCBP3
MTORENSG00000198793.82686.795703604.79650-0.424003.812901.63720K562PES1
MTORENSG00000198793.83753.542304949.37880-0.399004.116003.08920K562PPIG
MTORENSG00000198793.82496.924603702.24360-0.568207.403406.17930K562PRPF8
MTORENSG00000198793.82250.450103031.66320-0.429904.931503.67790K562PSIP1
MTORENSG00000198793.84030.383303228.389100.320003.602702.85630K562PTBP1
MTORENSG00000198793.86579.239208962.85430-0.446004.129102.94870K562PUM2
MTORENSG00000198793.84675.100205280.62570-0.175702.005801.30410K562SF3A3
MTORENSG00000198793.81822.272102642.55530-0.536205.063503.72590K562SF3B1
MTORENSG00000198793.82030.473602415.17180-0.250302.430701.63180K562SF3B4
MTORENSG00000198793.82096.346202658.23780-0.342602.953101.64500K562SLBP
MTORENSG00000198793.84140.196203165.038600.387405.075604.12100K562SRSF1
MTORENSG00000198793.82521.394503097.44720-0.296902.522201.62540K562TRIM56
MTORENSG00000198793.81575.693502325.33860-0.561509.353207.87280K562U2AF2
MTORENSG00000198793.84065.967404855.45340-0.256002.477901.64760K562WDR3
MTORENSG00000198793.84628.222906344.11460-0.455006.036004.68100K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MTOR is not available on ENCORE database.





6 RBPs can affect the splicing of MTOR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMTORENSG00000198793.8chr1-113076811130779011303170113033571130787511308151-0.260000.000000.00011excludedK562SF3B4
SEMTORENSG00000198793.8chr1-111770601117714311175452111755251118130211181425-0.098000.003020.05010excludedK562SF3B4
SEMTORENSG00000198793.8chr1-112050241120510211204704112048121120673211206848-0.230000.000020.00075excludedK562SF3B4
SEMTORENSG00000198793.8chr1-111944071119452311191650111932541119936011199492-0.090000.002520.06249excludedHepG2SF3A3
SEMTORENSG00000198793.8chr1-1130847311308559113078751130815111313895113140300.055000.003400.05344includedK562U2AF2
SEMTORENSG00000198793.8chr1-1117157011171810111697051116978611172908111729740.061000.000000.00002includedK562HNRNPC
A3SSMTORENSG00000198793.8chr1-1120470411204905112047041120481211205024112051020.060000.000110.01426longerK562AGGF1
A3SSMTORENSG00000198793.8chr1-1120470411204905112047041120481211205024112051020.133000.000500.02222longerK562U2AF2
A3SSMTORENSG00000198793.8chr1-1120470411204905112047041120481211205024112050900.150000.000000.00047longerK562SF3B4
A3SSMTORENSG00000198793.8chr1-111867501118685311186750111868401118706611187201-0.094000.001060.05436shorterK562SF3B4
A3SSMTORENSG00000198793.8chr1-1118809811188321111880981118818311188510111886090.086000.000000.00000longerK562AQR
A3SSMTORENSG00000198793.8chr1-1117706011177182111770601117714311181302111814250.060000.000430.00325longerK562AQR
A3SSMTORENSG00000198793.8chr1-1127087011270992112708701127096311272368112725430.163000.000000.00000longerK562AQR
A3SSMTORENSG00000198793.8chr1-1116934611169557111693461116942711169705111697860.064000.000000.00000longerK562AQR
A3SSMTORENSG00000198793.8chr1-1125941711259522112594171125946011259597112598070.103000.000000.00000longerK562AQR
A3SSMTORENSG00000198793.8chr1-1120470411204905112047041120481211205024112051760.080000.000000.00001longerK562AQR
A3SSMTORENSG00000198793.8chr1-1121720811217372112172081121734811227498112275740.176000.000000.00000longerK562AQR
MXEMTORENSG00000198793.8chr1-11227498112275741125941711259522112172081121734811259597112597600.180000.000000.000001includedK562AQR
MXEMTORENSG00000198793.8chr1-11227498112275741125931411259522112172081121734811259597112597600.180000.000000.000001includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MTOR is not avaliable on ENCORE database.