MTO1

General Information

Gene Name       : MTO1
Gene ID             : ENSG00000135297.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MTO1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MTO1ENSG00000135297.1523.9620.0422.00ENCSR000AEF
HepG2MTO1ENSG00000135297.1517.1019.9318.52ENCSR985KAT
K562MTO1ENSG00000135297.1535.1333.1834.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MTO1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MTO1 RNA is bound by 8 proteins.  







eCLIP assay for MTO1 is not avaliable on ENCORE database.





8 proteins are bound to MTO1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr67421032874210436+3'-UTR,CDS4.434016.09204K562YBX3
chr67418966474189828+3'-UTR,5'-UTR,CDS3.254043.80299HepG2GRWD1
chr67417626974176359+5'-UTR,CDS,intron-Proximal3.534938.55410K562PRPF8
chr67418984274189897+5'-UTR,CDS,intron-Proximal3.784414.77019K562BUD13
chr67417156574171660+5'-UTR,CDS,intron-Distal,intron-Proximal3.086344.08412K562RBM15
chr67417628474176356+5'-UTR,CDS,intron-Proximal4.5625317.91822HepG2PRPF8
chr67418999574190069+CDS,intron-Distal,intron-Proximal4.766339.08030K562AQR
chr67417638774176436+intron-Distal,intron-Proximal3.953183.02181K562PRPF8
chr67418178474181887+intron-Distal4.133073.41738HepG2PTBP1
chr67417816474178324+intron-Distal3.360353.46531K562KHSRP
chr67418984974189897+intron-Proximal6.6700120.26131K562AQR
chr67418989774189923+intron-Proximal3.560863.43550K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MTO1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MTO1 is not available on ENCORE database.

  • 69 RBPs can affect the levels of MTO1.  








The Knockdown/knockout RNA-Seq assay for MTO1 is not available on ENCORE database.





69 RBPs can affect the gene expression of MTO1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MTO1ENSG00000135297.11309.52490501.21850-0.695405.130904.22000HepG2CPSF6
MTO1ENSG00000135297.11549.54690414.410600.407102.324301.69540HepG2DDX21
MTO1ENSG00000135297.11647.55870466.193200.474004.034503.24630HepG2DKC1
MTO1ENSG00000135297.11333.25860415.79500-0.319202.023201.44910HepG2DNAJC2
MTO1ENSG00000135297.11399.22150698.57350-0.807207.304306.37490HepG2EIF2S1
MTO1ENSG00000135297.11477.62040771.98840-0.692705.450604.55460HepG2EIF4A3
MTO1ENSG00000135297.11825.77070683.772500.272102.289001.51490HepG2EIF4G1
MTO1ENSG00000135297.11520.59020778.95670-0.581404.538603.66770HepG2FXR1
MTO1ENSG00000135297.11486.99090722.56880-0.569204.043503.24780HepG2G3BP1
MTO1ENSG00000135297.11576.15520767.13570-0.413002.578001.72040HepG2G3BP2
MTO1ENSG00000135297.11304.20410471.08500-0.630904.343503.48930HepG2HNRNPC
MTO1ENSG00000135297.11562.52160731.73110-0.379402.316501.67400HepG2HNRNPK
MTO1ENSG00000135297.11465.84050687.19510-0.560905.458604.39370HepG2NOL12
MTO1ENSG00000135297.11516.49270714.23000-0.467602.985902.23790HepG2PABPC4
MTO1ENSG00000135297.11547.39010704.62690-0.364303.349702.69540HepG2PCBP1
MTO1ENSG00000135297.11544.67110716.94480-0.396503.671603.06060HepG2PTBP1
MTO1ENSG00000135297.11388.53480695.88630-0.8408010.263409.01540HepG2PUM2
MTO1ENSG00000135297.11641.21330776.55290-0.276301.956501.41690HepG2QKI
MTO1ENSG00000135297.11562.85510797.92340-0.503505.687504.95550HepG2NELFE
MTO1ENSG00000135297.11565.91150743.09780-0.393003.733803.03260HepG2RECQL
MTO1ENSG00000135297.11893.20300619.716000.527304.105003.29930HepG2RPLP0
MTO1ENSG00000135297.111009.02970579.772600.799306.816305.72490HepG2SF3A3
MTO1ENSG00000135297.11397.42150485.99850-0.290301.920701.36880HepG2SMN1
MTO1ENSG00000135297.11380.29410597.18720-0.651103.312602.45400HepG2SNRNP70
MTO1ENSG00000135297.11472.15500779.15840-0.722709.488508.73070HepG2SRSF1
MTO1ENSG00000135297.111091.54910710.560500.6192010.671909.79270HepG2SSB
MTO1ENSG00000135297.11609.15940471.374600.369801.906501.37470HepG2U2AF1
MTO1ENSG00000135297.11681.11900496.410800.456304.582403.84300HepG2UTP3
MTO1ENSG00000135297.11701.08060565.488300.310002.810702.26090HepG2ZNF622
MTO1ENSG00000135297.111298.657901926.84070-0.5692011.8006010.72150K562AGGF1
MTO1ENSG00000135297.111546.670902004.95300-0.374403.520102.77960K562AKAP8L
MTO1ENSG00000135297.111692.484302103.65560-0.313803.720302.64800K562ATP5C1
MTO1ENSG00000135297.11702.92900891.65780-0.343102.121201.36380K562BOP1
MTO1ENSG00000135297.11363.53480508.11830-0.483103.068701.94920K562CCAR1
MTO1ENSG00000135297.111163.150001389.48990-0.256502.410001.38470K562CPEB4
MTO1ENSG00000135297.11693.42240948.10140-0.451304.106103.15050K562CPSF6
MTO1ENSG00000135297.112069.376602547.62380-0.300002.934101.93150K562CELF1
MTO1ENSG00000135297.11599.63480794.63930-0.406203.275002.13250K562DDX3X
MTO1ENSG00000135297.11385.73100546.41300-0.502403.477201.95960K562DNAJC21
MTO1ENSG00000135297.11806.96900992.28150-0.298202.418801.67260K562EIF3G
MTO1ENSG00000135297.111676.518102072.13370-0.305603.434702.39120K562EIF4G2
MTO1ENSG00000135297.11760.36050964.64490-0.343302.295401.51420K562FMR1
MTO1ENSG00000135297.11571.62310817.61240-0.516403.851602.75740K562FTO
MTO1ENSG00000135297.11677.32640905.21410-0.418403.323502.45480K562GPKOW
MTO1ENSG00000135297.111346.952501762.29380-0.387803.769302.89170K562GRSF1
MTO1ENSG00000135297.11626.65650872.89750-0.478104.099503.38780K562HNRNPC
MTO1ENSG00000135297.11585.54930779.40690-0.412602.978201.79130K562HNRNPF
MTO1ENSG00000135297.112374.275501568.844000.597707.538106.24270K562HSPD1
MTO1ENSG00000135297.11576.03990772.91210-0.424102.104201.30120K562KRR1
MTO1ENSG00000135297.11863.857401208.78490-0.484705.053603.91070K562MAGOH
MTO1ENSG00000135297.111892.478002383.66600-0.332903.530002.48490K562MBNL1
MTO1ENSG00000135297.11663.59350883.58550-0.413103.264502.31150K562METAP2
MTO1ENSG00000135297.11769.917401071.60140-0.477006.610705.41010K562MTPAP
MTO1ENSG00000135297.11963.909501190.68540-0.304803.920503.05130K562NSUN2
MTO1ENSG00000135297.11892.555601156.93490-0.374302.446201.66580K562PCBP3
MTO1ENSG00000135297.11707.58850887.43030-0.326702.402901.65800K562POLR2G
MTO1ENSG00000135297.11588.84470782.61850-0.410403.120402.15320K562PSIP1
MTO1ENSG00000135297.11967.241901174.43200-0.280002.178301.57760K562PTBP1
MTO1ENSG00000135297.111764.981302356.24000-0.416806.057004.61960K562PUM2
MTO1ENSG00000135297.111327.701201988.44970-0.582707.256806.42450K562PUS1
MTO1ENSG00000135297.111444.229401937.37310-0.423805.803004.97090K562RBM15
MTO1ENSG00000135297.11863.534801125.98060-0.382903.072402.18210K562RBM22
MTO1ENSG00000135297.11515.73990676.78520-0.392102.425901.48200K562SRFBP1
MTO1ENSG00000135297.11976.256401203.64680-0.302103.564202.51800K562SRPK2
MTO1ENSG00000135297.11531.663701151.36770-1.1148021.7289019.76370K562SRSF1
MTO1ENSG00000135297.11561.87450802.71670-0.514603.431702.28760K562SUPV3L1
MTO1ENSG00000135297.11894.271701165.18860-0.381802.843702.12700K562TARDBP
MTO1ENSG00000135297.11507.36790752.76300-0.569204.240103.06080K562TIAL1
MTO1ENSG00000135297.11588.68170799.57620-0.441703.397202.33020K562TRIM56
MTO1ENSG00000135297.111163.519101409.73130-0.276902.852001.56270K562TROVE2
MTO1ENSG00000135297.11638.97430849.51370-0.410902.650401.65590K562UCHL5
MTO1ENSG00000135297.111618.634402060.28900-0.348103.402601.96210K562WRN
MTO1ENSG00000135297.11557.294301005.73900-0.851704.763502.54330K562XRCC6
MTO1ENSG00000135297.111473.823201959.05720-0.410604.213103.10990K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MTO1 is not available on ENCORE database.





25 RBPs can affect the splicing of MTO1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMTO1ENSG00000135297.11chr6+7418118274181280741762117417632974183087741831970.170000.000210.02466includedHepG2G3BP1
SEMTO1ENSG00000135297.11chr6+741830877418337774176211741763297418945474189567-0.114000.001280.02568excludedK562SRSF1
SEMTO1ENSG00000135297.11chr6+742074587420761974201956742020757421029674210819-0.138000.000120.00358excludedK562SF3B4
SEMTO1ENSG00000135297.11chr6+741900157419009074189761741898497419039774190528-0.114000.004630.06972excludedK562SF3B4
SEMTO1ENSG00000135297.11chr6+7419001574190090741896587418984974190397741905280.266000.005690.08375includedHepG2U2AF1
SEMTO1ENSG00000135297.11chr6+7419001574190090741896587418984974190397741905280.579000.000000.00000includedK562XRCC6
SEMTO1ENSG00000135297.11chr6+741830877418337774176211741763297418945474189567-0.096000.002280.02804excludedHepG2U2AF2
SEMTO1ENSG00000135297.11chr6+741830877418337774176247741763297418945474189567-0.094000.000680.00878excludedK562AQR
SEMTO1ENSG00000135297.11chr6+742074587420761974201956742020757421029674211175-0.083000.000510.00693excludedK562AQR
SEMTO1ENSG00000135297.11chr6+741811827418128074176211741763297418308774183197-0.084000.000720.03010excludedK562FXR1
SEMTO1ENSG00000135297.11chr6+741963207419648474192171741923437420195674202075-0.084000.000200.02185excludedHepG2DDX3X
SEMTO1ENSG00000135297.11chr6+7419004074190090741897617418984974190397741904850.256000.000180.01978includedK562SUPV3L1
SEMTO1ENSG00000135297.11chr6+742074587420761974201956742020757421029674210819-0.077000.000010.00034excludedK562PUS1
SEMTO1ENSG00000135297.11chr6+741900157419009074189658741898497419039774190528-0.175000.002620.09042excludedHepG2SFPQ
SEMTO1ENSG00000135297.11chr6+7419001574190090741896587418984974190397741905280.422000.000000.00000includedK562U2AF1
SEMTO1ENSG00000135297.11chr6+742074587420761974201956742020757421029674210819-0.146000.000070.00241excludedK562U2AF1
SEMTO1ENSG00000135297.11chr6+741830877418337774176211741763297418945474189567-0.063000.000270.04488excludedK562HNRNPM
SEMTO1ENSG00000135297.11chr6+7419004074190090741897617418984974190397741904850.142000.000260.02321includedK562HNRNPL
SEMTO1ENSG00000135297.11chr6+7418118274181280741762117417632974183087741831970.054000.000250.06552includedK562PPIL4
SEMTO1ENSG00000135297.11chr6+741830877418337774176211741763297418945474189567-0.145000.002770.05639excludedHepG2SRSF1
SEMTO1ENSG00000135297.11chr6+741900157419009074189761741898497419039774190528-0.217000.000240.02258excludedHepG2TIAL1
SEMTO1ENSG00000135297.11chr6+7419001574190090741896587418984974190397741905280.319000.000070.03554includedHepG2BCCIP
SEMTO1ENSG00000135297.11chr6+742074587420761974201956742020757421029674210819-0.099000.002850.04644excludedK562U2AF2
SEMTO1ENSG00000135297.11chr6+742074587420761974201956742020757421029674210819-0.074000.000040.00223excludedK562RBM15
SEMTO1ENSG00000135297.11chr6+742074587420761974201956742020757421029674210819-0.084000.000000.00025excludedK562AGGF1
SEMTO1ENSG00000135297.11chr6+7419001574190090741896587418984974190397741905280.267000.000380.08222includedHepG2FUBP3
SEMTO1ENSG00000135297.11chr6+7418118274181280741762117417632974183087741831970.107000.000310.06968includedHepG2FUBP3
SEMTO1ENSG00000135297.11chr6+741900157419009074189658741898497419039774190528-0.215000.000780.03526excludedHepG2HNRNPU
SEMTO1ENSG00000135297.11chr6+741811827418128074176211741763297418308774183197-0.087000.002870.09442excludedHepG2HNRNPU
SEMTO1ENSG00000135297.11chr6+7419072374190839741903977419052874191762741919670.311000.001010.03892includedHepG2HNRNPC
SEMTO1ENSG00000135297.11chr6+7418118274181280741762117417632974183087741831970.182000.002330.07395includedHepG2HNRNPC
SEMTO1ENSG00000135297.11chr6+741907237419083974190489741905287419176274191967-0.075000.000200.01142excludedK562PTBP1
SEMTO1ENSG00000135297.11chr6+7419072374190839741903977419052874191762741919670.698000.000000.00000includedK562HNRNPC
SEMTO1ENSG00000135297.11chr6+7419001574190090741896587418984974190397741905280.642000.000000.00000includedK562HNRNPC
SEMTO1ENSG00000135297.11chr6+7418118274181280741762117417632974183087741831970.442000.000000.00000includedK562HNRNPC
SEMTO1ENSG00000135297.11chr6+741830877418337774176211741763297418945474189567-0.096000.002020.03424excludedK562HNRNPC
A3SSMTO1ENSG00000135297.11chr6+7419172474191967741917627419196774190397741905280.055000.000430.00330longerK562AQR
A3SSMTO1ENSG00000135297.11chr6+741896587418984974189761741898497418945474189567-0.109000.000290.00232shorterK562AQR
A3SSMTO1ENSG00000135297.11chr6+7419175174191967741917627419196774190397741905280.319000.000000.00028longerK562U2AF1
A3SSMTO1ENSG00000135297.11chr6+7419175174191967741917627419196774190397741905280.427000.000000.00088longerK562HNRNPC
A5SSMTO1ENSG00000135297.11chr6+7418965874190090741896587418984974190397741905280.451000.000000.00000longerK562U2AF1
A5SSMTO1ENSG00000135297.11chr6+7418965874190090741896587418984974190397741905280.289000.000050.01933longerHepG2FUBP3
A5SSMTO1ENSG00000135297.11chr6+741896587419009074189658741898497419039774190528-0.227000.000070.09023shorterHepG2SLTM
A5SSMTO1ENSG00000135297.11chr6+741896587419009074189658741898497419039774190528-0.241000.000330.05932shorterHepG2HNRNPU
A5SSMTO1ENSG00000135297.11chr6+7418965874190090741896587418984974190397741905280.573000.000000.00000longerK562XRCC6
A5SSMTO1ENSG00000135297.11chr6+741896587419009074189658741898497419039774190528-0.240000.000150.02678shorterHepG2TIAL1
A5SSMTO1ENSG00000135297.11chr6+7418965874190090741896587418984974190397741905280.637000.000000.00000longerK562HNRNPC
A5SSMTO1ENSG00000135297.11chr6+741896587419009074189658741898497419039774190528-0.169000.000730.07095shorterK562EFTUD2
A5SSMTO1ENSG00000135297.11chr6+7418965874190090741896587418984974190397741905280.283000.000170.05759longerHepG2BCCIP
RIMTO1ENSG00000135297.11chr6+741894547418984974189454741895677418976174189849-0.093000.001720.01102excludedK562AQR
MXEMTO1ENSG00000135297.11chr6+74176247741763297418965874189849741759317417613174190397741905280.061000.012860.077651includedK562AQR
MXEMTO1ENSG00000135297.11chr6+74176247741763297418308774183377741759317417613174189454741895670.097000.000200.002251includedK562AQR
MXEMTO1ENSG00000135297.11chr6+74192171741923437420195674202075741903977419052874207458742076190.079000.000070.000931includedK562AQR
MXEMTO1ENSG00000135297.11chr6+7419217174192343742019567420207574191854741919677421029674210424-0.113000.000300.003162includedK562AQR
MXEMTO1ENSG00000135297.11chr6+7419217174192343742019567420207574191854741919677421029674210424-0.252000.000020.000562includedK562U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MTO1 is not avaliable on ENCORE database.