MRS2

General Information

Gene Name       : MRS2
Gene ID             : ENSG00000124532.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MRS2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MRS2ENSG00000124532.1416.5516.1116.33ENCSR000AEF
HepG2MRS2ENSG00000124532.1435.0656.3545.70ENCSR985KAT
K562MRS2ENSG00000124532.1431.0531.5831.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MRS2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MRS2 RNA is bound by 18 proteins.  







eCLIP assay for MRS2 is not avaliable on ENCORE database.





18 proteins are bound to MRS2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr62441873624418806+3'-UTR,CDS3.352104.61143K562UCHL5
chr62441880324418818+3'-UTR,CDS,intron-Proximal4.663819.56266K562AQR
chr62441530124415368+3'-UTR,CDS,intron-Distal3.176663.71797HepG2BCLAF1
chr62442386324423938+3'-UTR,CDS4.403275.02622HepG2SRSF1
chr62441871924418809+3'-UTR,CDS,intron-Proximal3.113875.59833HepG2GRWD1
chr62441672024416745+3'-UTR,CDS,intron-Proximal3.345604.34695HepG2BCLAF1
chr62442441724424451+3'-UTR5.804448.10826K562PABPC4
chr62441836024418436+3'-UTR,CDS3.550735.28199HepG2GRWD1
chr62442515924425196+3'-UTR4.356324.36811K562FAM120A
chr62441834924418415+3'-UTR,CDS3.221643.58614K562YBX3
chr62441831024418359+3'-UTR,CDS,intron-Proximal3.541146.55026K562ZNF622
chr62441666424416743+3'-UTR,CDS,intron-Proximal4.039843.65778K562GRWD1
chr62441831124418359+3'-UTR,CDS,intron-Proximal3.657635.56491HepG2BCLAF1
chr62442470124424762+3'-UTR3.126614.79181K562FAM120A
chr62441831024418391+3'-UTR,CDS,intron-Proximal3.971093.02919K562GRWD1
chr62441664724416720+3'-UTR,CDS3.486958.74800HepG2BCLAF1
chr62440332624403414+5'-UTR,CDS3.599906.51082HepG2PPIG
chr62440317424403270+5'-UTR3.410716.40214HepG2NCBP2
chr62440864824408706+5'-UTR,CDS,intron-Distal,intron-Proximal4.223463.85435K562PRPF8
chr62440317524403396+5'-UTR,CDS3.3976716.66569K562DDX3X
chr62440342224403512+5'-UTR,CDS,intron-Proximal5.389948.04585HepG2PRPF8
chr62440318024403229+5'-UTR4.653708.20930HepG2DDX3X
chr62440322924403358+5'-UTR,CDS3.709217.54621HepG2DDX3X
chr62440965824409789+5'-UTR,CDS,intron-Distal,intron-Proximal3.867475.90528HepG2AQR
chr62440545324405551+CDS,intron-Distal,intron-Proximal5.131427.79404K562PRPF8
chr62440537324405497+CDS,intron-Distal,intron-Proximal3.193857.79150HepG2BUD13
chr62440542924405473+CDS,intron-Distal,intron-Proximal4.054083.60441HepG2GRWD1
chr62440546824405502+CDS,intron-Distal,intron-Proximal3.859696.21987K562AQR
chr62440550224405527+intron-Distal,intron-Proximal4.070515.35619K562AQR
chr62441947924419604+intron-Distal3.028844.14978K562KHDRBS1
chr62441685224416900+intron-Distal4.064383.49003K562PRPF8
chr62441266324412689+intron-Distal,intron-Proximal3.617404.96160K562KHSRP
chr62441883424418879+intron-Proximal4.364585.75804K562RBM22
chr62441881824418853+intron-Proximal3.4293511.79789K562AQR
chr62441882724418883+intron-Proximal3.749706.74060K562PRPF8
chr62441883324418884+intron-Proximal4.439349.46423HepG2RBM22
chr62441882924418894+intron-Proximal4.111514.71457HepG2PRPF8
chr62441882724418902+intron-Proximal3.783149.43339K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MRS2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MRS2 is not available on ENCORE database.

  • 78 RBPs can affect the levels of MRS2.  








The Knockdown/knockout RNA-Seq assay for MRS2 is not available on ENCORE database.





78 RBPs can affect the gene expression of MRS2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MRS2ENSG00000124532.10997.113201302.20840-0.385105.005904.00010HepG2AKAP8L
MRS2ENSG00000124532.101827.962401369.546200.416403.358502.49290HepG2ASCC1
MRS2ENSG00000124532.101245.100402261.33500-0.8609027.1617025.40700HepG2AUH
MRS2ENSG00000124532.10940.309601212.92190-0.367302.141601.34710HepG2BCLAF1
MRS2ENSG00000124532.101491.270901945.53020-0.383602.282101.40560HepG2CCAR1
MRS2ENSG00000124532.101595.911601295.836800.300404.327303.53060HepG2CKAP4
MRS2ENSG00000124532.10894.323301532.40370-0.776906.475105.45620HepG2CPSF6
MRS2ENSG00000124532.101782.587402117.27210-0.248203.901903.04530HepG2DAZAP1
MRS2ENSG00000124532.10639.040401198.72490-0.9075025.0474023.15350HepG2DDX19B
MRS2ENSG00000124532.101570.304801082.145500.537106.035105.07790HepG2DDX21
MRS2ENSG00000124532.102370.361801585.581500.580006.061005.16930HepG2DDX3X
MRS2ENSG00000124532.10983.674901361.96110-0.469403.249002.58500HepG2DDX6
MRS2ENSG00000124532.10635.046001187.63650-0.9032015.2791013.74630HepG2DNAJC21
MRS2ENSG00000124532.10893.878301177.00680-0.397003.469602.75400HepG2DNAJC2
MRS2ENSG00000124532.10752.731101309.37180-0.798709.179508.13800HepG2EIF2S1
MRS2ENSG00000124532.101037.332301408.82840-0.441602.482501.82950HepG2EIF4B
MRS2ENSG00000124532.101514.959302000.82340-0.401303.829802.88240HepG2EIF4G2
MRS2ENSG00000124532.102121.632502596.30530-0.291303.856303.16680HepG2ETF1
MRS2ENSG00000124532.101629.653801266.539500.363602.093401.36780HepG2EWSR1
MRS2ENSG00000124532.101829.123801459.888700.325202.252801.62590HepG2FXR1
MRS2ENSG00000124532.10933.393601737.23610-0.896207.269706.26290HepG2GPKOW
MRS2ENSG00000124532.101649.293801945.73920-0.238502.667901.74810HepG2HNRNPA2B1
MRS2ENSG00000124532.10895.831401333.63280-0.574106.336905.32190HepG2HNRNPC
MRS2ENSG00000124532.101074.992201452.98400-0.434706.451305.41860HepG2HNRNPF
MRS2ENSG00000124532.101577.401701928.73220-0.290104.955804.07390HepG2HNRNPL
MRS2ENSG00000124532.10724.818201324.81910-0.8701018.4787017.01690HepG2HNRNPU
MRS2ENSG00000124532.101012.121601430.77450-0.499406.188105.14810HepG2IGF2BP1
MRS2ENSG00000124532.101722.155501317.770300.386003.663902.26230HepG2LIN28B
MRS2ENSG00000124532.101960.221401468.591900.416503.023102.36680HepG2MATR3
MRS2ENSG00000124532.102007.968801503.202000.417603.248302.56390HepG2NCBP2
MRS2ENSG00000124532.101776.726002099.47210-0.240802.401901.69310HepG2NOL12
MRS2ENSG00000124532.10701.447601260.07490-0.845104.965403.47860HepG2NONO
MRS2ENSG00000124532.10632.90650900.11350-0.508102.325001.52510HepG2PABPC1
MRS2ENSG00000124532.101014.855601338.77550-0.399602.792502.06730HepG2PABPC4
MRS2ENSG00000124532.10797.616501311.40320-0.7173012.1867010.61710HepG2PARN
MRS2ENSG00000124532.101392.155501185.085200.232202.065701.38890HepG2PRPF4
MRS2ENSG00000124532.102049.754601420.343200.529103.231701.92150HepG2PRPF6
MRS2ENSG00000124532.101663.224602004.07550-0.269002.293701.74390HepG2PUF60
MRS2ENSG00000124532.101897.114102127.35090-0.165302.129901.59600HepG2PUM1
MRS2ENSG00000124532.101643.235602170.03290-0.401206.156305.45800HepG2RBM22
MRS2ENSG00000124532.101725.004801301.781500.406004.358103.52800HepG2RBM25
MRS2ENSG00000124532.10918.883501228.68560-0.419202.282701.32190HepG2RCC2
MRS2ENSG00000124532.102246.668901473.958600.6080014.0489013.00630HepG2NELFE
MRS2ENSG00000124532.101641.470001372.851900.257702.893402.26450HepG2RECQL
MRS2ENSG00000124532.101041.652701565.21890-0.587507.081606.06370HepG2RPLP0
MRS2ENSG00000124532.10944.152201179.83780-0.321503.174702.49460HepG2SAFB2
MRS2ENSG00000124532.10877.189001641.03700-0.903607.678806.55450HepG2SF3B1
MRS2ENSG00000124532.101494.201901921.46510-0.362805.449704.52160HepG2SLBP
MRS2ENSG00000124532.101032.437101375.93730-0.414404.299503.52930HepG2SMN1
MRS2ENSG00000124532.10930.832401328.60100-0.513303.361402.29480HepG2SMNDC1
MRS2ENSG00000124532.103035.449701439.258001.0765049.3457047.89210HepG2SRSF1
MRS2ENSG00000124532.101311.796001765.53640-0.428602.428501.49670HepG2SRSF3
MRS2ENSG00000124532.101749.196601978.65620-0.177801.824201.30160HepG2SRSF5
MRS2ENSG00000124532.101183.624801427.50860-0.270302.943502.22910HepG2SRSF7
MRS2ENSG00000124532.102652.062302128.033700.317505.325504.65990HepG2SSB
MRS2ENSG00000124532.101098.467702250.34260-1.0347044.7887042.82390HepG2SUCLG1
MRS2ENSG00000124532.10742.913101025.32550-0.464803.404802.36970HepG2SUPT6H
MRS2ENSG00000124532.101017.449501615.54050-0.667105.554604.58030HepG2TARDBP
MRS2ENSG00000124532.10940.251101287.48670-0.453405.361804.71230HepG2TIAL1
MRS2ENSG00000124532.10848.787001298.80540-0.613708.355907.46000HepG2TRIM56
MRS2ENSG00000124532.101669.785702072.22440-0.311502.143701.41210HepG2UBE2L3
MRS2ENSG00000124532.101817.799801234.577200.5581011.6411010.54690HepG2UTP3
MRS2ENSG00000124532.10933.548101281.95220-0.457502.540601.33890HepG2XRCC5
MRS2ENSG00000124532.10715.567401169.49860-0.7087015.1977013.82820HepG2ZC3H8
MRS2ENSG00000124532.101192.688001406.37270-0.237802.859202.30590HepG2ZNF622
MRS2ENSG00000124532.101664.391802641.32780-0.666309.793408.79340K562AQR
MRS2ENSG00000124532.102443.215103127.97440-0.356403.840101.50120K562AUH
MRS2ENSG00000124532.101344.794201660.79490-0.304502.129701.37070K562BOP1
MRS2ENSG00000124532.101624.191502276.98960-0.487402.440801.45320K562CNOT7
MRS2ENSG00000124532.101017.684201765.88940-0.7951014.5318012.70030K562CPSF6
MRS2ENSG00000124532.101058.489701609.70930-0.604806.866704.54480K562DDX19B
MRS2ENSG00000124532.10965.927101246.71080-0.368102.601801.71970K562EFTUD2
MRS2ENSG00000124532.101354.525602022.52300-0.5784010.600309.33180K562EIF2S2
MRS2ENSG00000124532.101702.693701372.845000.310603.683103.00030K562FXR1
MRS2ENSG00000124532.101817.724501295.712900.488303.402102.60280K562G3BP2
MRS2ENSG00000124532.10993.425901685.98010-0.7631011.9708010.30250K562GPKOW
MRS2ENSG00000124532.10659.658801172.75330-0.8301012.4551011.26340K562HNRNPC
MRS2ENSG00000124532.101299.391401839.28410-0.501307.743606.25620K562HNRNPU
MRS2ENSG00000124532.101741.787901415.722700.298902.026201.54790K562PUS1
MRS2ENSG00000124532.10733.17200959.44580-0.388003.144502.08090K562RCC2
MRS2ENSG00000124532.101267.456601723.03570-0.443006.717705.49600K562SF3A3
MRS2ENSG00000124532.10697.76560909.52100-0.382402.764601.74110K562SRFBP1
MRS2ENSG00000124532.101805.348702858.57300-0.6630013.2531010.44380K562SUCLG1
MRS2ENSG00000124532.101041.476601610.37180-0.628804.553903.64180K562TARDBP
MRS2ENSG00000124532.101190.908401553.33900-0.383302.908302.06680K562TIA1
MRS2ENSG00000124532.10771.572601011.36950-0.390402.557801.66150K562TIAL1
MRS2ENSG00000124532.102849.317703693.76680-0.374504.043502.33910K562UBE2L3
MRS2ENSG00000124532.10929.138801243.23480-0.420103.202302.10260K562UCHL5
MRS2ENSG00000124532.101252.255701652.71420-0.400302.727101.53500K562UTP3
MRS2ENSG00000124532.101303.366001584.31200-0.281602.345001.53800K562WDR3
MRS2ENSG00000124532.102561.930703129.29630-0.288602.739701.45820K562WRN
MRS2ENSG00000124532.102357.269802975.63730-0.336103.270202.32250K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MRS2 is not available on ENCORE database.





10 RBPs can affect the splicing of MRS2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMRS2ENSG00000124532.10chr6+2442319224423278244185982441880624423811244242510.053000.006920.09742includedHepG2U2AF1
SEMRS2ENSG00000124532.10chr6+244231642442327824418598244188062442381124425810-0.068000.000590.00781excludedK562AQR
SEMRS2ENSG00000124532.10chr6+244086352440867224405395244054692441244924412623-0.060000.012430.09641excludedK562AQR
SEMRS2ENSG00000124532.10chr6+244231642442327824418688244188062442381124424122-0.116000.000010.00105excludedK562TARDBP
SEMRS2ENSG00000124532.10chr6+244231642442327824418688244188062442381124424122-0.127000.000130.00812excludedK562SF3B1
A3SSMRS2ENSG00000124532.10chr6+244152432441539124415260244153912441244924412623-0.073000.000200.01009shorterK562U2AF2
A3SSMRS2ENSG00000124532.10chr6+2441524324415391244152602441539124412449244126230.064000.007710.04222longerK562AQR
A3SSMRS2ENSG00000124532.10chr6+2441859824418806244186882441880624418311244184640.091000.000000.00032longerK562PUS1
A3SSMRS2ENSG00000124532.10chr6+2441524324415391244152602441539124412449244126230.086000.000050.08128longerK562UTP3
A3SSMRS2ENSG00000124532.10chr6+2441524324415391244152602441539124412449244126230.082000.000700.09284longerK562SF3B1
A3SSMRS2ENSG00000124532.10chr6+2441524324415391244152602441539124412449244126230.123000.000520.06244longerK562HNRNPC
MXEMRS2ENSG00000124532.10chr6+24405395244054692440968824409801244031812440346424412449244126230.162000.004280.090181includedHepG2MATR3
MXEMRS2ENSG00000124532.10chr6+24405395244054692440968824409801244031812440346424412449244126230.165000.003910.096321includedHepG2NCBP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MRS2 is not avaliable on ENCORE database.