MGME1

General Information

Gene Name       : MGME1
Gene ID             : ENSG00000125871.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MGME1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MGME1ENSG00000125871.1330.8730.4730.67ENCSR000AEF
HepG2MGME1ENSG00000125871.1342.0066.6954.34ENCSR985KAT
K562MGME1ENSG00000125871.1329.8230.3630.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MGME1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MGME1 RNA is bound by 23 proteins.  







eCLIP assay for MGME1 is not avaliable on ENCORE database.





23 proteins are bound to MGME1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr201797145617971555+3'-UTR4.731357.56405K562PUM2
chr201797160917971683+3'-UTR3.001474.03372K562UPF1
chr201797157017971669+3'-UTR3.951375.93237HepG2DDX55
chr201797105917971112+3'-UTR5.3822714.02112HepG2FAM120A
chr201797111017971215+3'-UTR4.490577.31669K562FAM120A
chr201797105017971175+3'-UTR4.4093010.16433HepG2UPF1
chr201797161417971697+3'-UTR3.397975.74446HepG2ZC3H11A
chr201797150817971560+3'-UTR3.876855.81489K562UPF1
chr201797105817971098+3'-UTR3.738715.75623K562FAM120A
chr201797105917971139+3'-UTR3.059036.70197HepG2LSM11
chr201797148817971636+3'-UTR3.273538.31160K562ZC3H11A
chr201794977317949814+5'-UTR,intron-Proximal4.066474.16174HepG2PRPF8
chr201795046617950499+5'-UTR3.210353.60157HepG2GRWD1
chr201794971717949785+5'-UTR,intron-Proximal3.121875.50895HepG2NCBP2
chr201796881517968915+CDS,intron-Distal3.771155.30069HepG2AQR
chr201795628817956388+CDS,intron-Distal,intron-Proximal3.227713.41609HepG2U2AF1
chr201795066817950724+CDS4.010014.12025K562YBX3
chr201795055717950614+CDS4.990027.81713K562RBM15
chr201795087317950922+CDS,intron-Distal4.165564.22893K562RBM15
chr201795084617950931+CDS,intron-Distal,intron-Proximal3.134417.54832HepG2GRWD1
chr201795629117956382+CDS,intron-Distal,intron-Proximal3.306954.26865K562U2AF2
chr201796890617968976+CDS,intron-Distal,intron-Proximal4.288113.89565K562PRPF8
chr201795097317951061+CDS,intron-Distal,intron-Proximal3.859424.89564K562GPKOW
chr201795628817956391+CDS,intron-Distal,intron-Proximal3.0015711.54083HepG2U2AF2
chr201795054117950635+CDS4.040983.71734HepG2RBM15
chr201796893317968977+CDS,intron-Distal,intron-Proximal3.961735.62208HepG2PRPF8
chr201795650917956553+CDS,intron-Distal,intron-Proximal3.292204.24993HepG2PPIG
chr201795058217950643+CDS3.389797.74581HepG2BCLAF1
chr201795654517956581+CDS,intron-Distal,intron-Proximal4.3377711.67817HepG2PRPF8
chr201795066617950823+CDS,intron-Proximal3.358097.55111K562UCHL5
chr201795052917950639+CDS3.358576.66900HepG2GRWD1
chr201795094617950997+CDS,intron-Distal4.320734.48994K562RBM15
chr201795066717950846+CDS,intron-Proximal3.3911613.25242HepG2GRWD1
chr201795093117951022+CDS,intron-Distal,intron-Proximal3.085789.65386HepG2GRWD1
chr201795068117950727+CDS4.568964.82934K562RBM15
chr201796879717968860+CDS,intron-Distal,intron-Proximal4.198466.08476K562GPKOW
chr201795652117956545+CDS,intron-Distal4.5917913.40522HepG2PRPF8
chr201795074217950794+CDS,intron-Proximal3.402276.20035HepG2BCLAF1
chr201796887817968912+CDS,intron-Distal3.638084.85828HepG2BCLAF1
chr201796230117962366+intron-Distal4.371354.39969K562TARDBP
chr201796794317967999+intron-Distal3.338955.94773HepG2QKI
chr201795346517953530+intron-Distal4.4014825.67502HepG2QKI
chr201796150517961563+intron-Distal4.851625.89032HepG2QKI
chr201796494317965057+intron-Distal3.527905.03298HepG2HNRNPL
chr201795155617951604+intron-Distal4.5230610.94082HepG2QKI
chr201796364617963742+intron-Distal5.0456612.42112HepG2PCBP2
chr201796799917968038+intron-Distal3.656044.83406HepG2QKI
chr201795160417951650+intron-Distal3.575505.69331HepG2QKI
chr201795448117954529+intron-Distal3.628819.03661HepG2QKI
chr201795153917951651+intron-Distal4.974635.58608K562QKI
chr201796895017968987+intron-Distal,intron-Proximal4.323596.39176K562AQR
chr201796511417965175+intron-Distal3.934973.45317HepG2HNRNPL
chr201795111117951149+intron-Distal,intron-Proximal3.592613.94088HepG2QKI
chr201795346317953577+intron-Distal4.497059.57828K562QKI
chr201796894117968950+intron-Distal,intron-Proximal4.739114.48002K562AQR
chr201795434317954395+intron-Distal4.477343.40087HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MGME1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MGME1 is not available on ENCORE database.

  • 85 RBPs can affect the levels of MGME1.  








The Knockdown/knockout RNA-Seq assay for MGME1 is not available on ENCORE database.





85 RBPs can affect the gene expression of MGME1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MGME1ENSG00000125871.91141.389901689.82500-0.566104.631503.96620HepG2AKAP1
MGME1ENSG00000125871.9945.364301349.11000-0.513103.717002.68790HepG2BCLAF1
MGME1ENSG00000125871.91058.028301456.24990-0.460905.511704.47140HepG2CALR
MGME1ENSG00000125871.9745.661101212.81890-0.701808.074006.95000HepG2CPSF6
MGME1ENSG00000125871.91900.909702425.98700-0.351907.150406.03790HepG2DAZAP1
MGME1ENSG00000125871.91030.883101618.76870-0.651006.782805.84600HepG2DDX3X
MGME1ENSG00000125871.9963.529501390.45170-0.529204.023303.28950HepG2DDX6
MGME1ENSG00000125871.9911.793301354.41640-0.570904.181103.38270HepG2DKC1
MGME1ENSG00000125871.9931.077701302.78810-0.484606.730505.67070HepG2DNAJC21
MGME1ENSG00000125871.9966.145201291.20060-0.418406.954505.98620HepG2DNAJC2
MGME1ENSG00000125871.9704.348901336.77830-0.9244011.9902010.81090HepG2EIF2S1
MGME1ENSG00000125871.9899.246401477.34710-0.716206.959805.94680HepG2EIF4A3
MGME1ENSG00000125871.91882.958202393.36870-0.346004.557603.52460HepG2EIF4G1
MGME1ENSG00000125871.91447.117202292.69700-0.663909.139307.69620HepG2EIF4G2
MGME1ENSG00000125871.91692.464802622.86690-0.6320015.5823014.34750HepG2ETF1
MGME1ENSG00000125871.91060.728101383.57150-0.383302.247601.49510HepG2EWSR1
MGME1ENSG00000125871.9735.961201214.90300-0.723102.915501.87160HepG2FTO
MGME1ENSG00000125871.9569.97690816.99680-0.519404.011102.92060HepG2GEMIN5
MGME1ENSG00000125871.9872.082901374.81760-0.656706.248005.31200HepG2GPKOW
MGME1ENSG00000125871.9681.137201315.26820-0.9493015.6965014.36280HepG2HNRNPA1
MGME1ENSG00000125871.91764.037502229.54240-0.337904.953103.76180HepG2HNRNPA2B1
MGME1ENSG00000125871.9874.092801462.96500-0.7430010.296309.03410HepG2HNRNPC
MGME1ENSG00000125871.91069.410001466.44700-0.455507.281106.18800HepG2HNRNPF
MGME1ENSG00000125871.91558.270302209.89420-0.5040012.9290011.57010HepG2HNRNPL
MGME1ENSG00000125871.9811.827201312.01440-0.692507.638806.65220HepG2HNRNPLL
MGME1ENSG00000125871.91167.336501453.29480-0.316103.953503.23960HepG2HNRNPU
MGME1ENSG00000125871.91103.034801444.02790-0.388604.101503.23490HepG2IGF2BP1
MGME1ENSG00000125871.91107.876801405.48420-0.343302.261701.64400HepG2IGF2BP2
MGME1ENSG00000125871.91080.986501484.49730-0.457609.688508.39870HepG2ILF2
MGME1ENSG00000125871.91489.098501900.46540-0.351902.045601.34060HepG2LARP4
MGME1ENSG00000125871.91705.528201139.101700.582207.909306.60630HepG2MSI2
MGME1ENSG00000125871.9595.87950956.48200-0.682707.844305.83220HepG2NAA15
MGME1ENSG00000125871.91042.392901351.43300-0.374602.839901.40210HepG2NIP7
MGME1ENSG00000125871.9782.665901163.35680-0.571805.421604.39040HepG2NSUN2
MGME1ENSG00000125871.9933.817701366.80340-0.549604.813303.87270HepG2PABPC4
MGME1ENSG00000125871.91059.497801462.12200-0.464702.611001.60090HepG2PCBP2
MGME1ENSG00000125871.91105.214401296.22770-0.230001.934601.30990HepG2PPIL4
MGME1ENSG00000125871.9796.679801177.76330-0.564004.493403.49010HepG2PRPF8
MGME1ENSG00000125871.91963.563101458.392500.429007.177206.37690HepG2PTBP1
MGME1ENSG00000125871.9972.817702296.35300-1.2391032.6095030.84310HepG2PUF60
MGME1ENSG00000125871.91977.555502437.67380-0.301805.605504.82380HepG2PUM1
MGME1ENSG00000125871.9912.762002435.89710-1.4161049.8400047.32420HepG2PUM2
MGME1ENSG00000125871.91603.562702192.24550-0.451106.868706.13870HepG2RBM22
MGME1ENSG00000125871.9876.379201433.46310-0.7099010.621609.36060HepG2RBM25
MGME1ENSG00000125871.91405.312801623.04190-0.207801.880301.41530HepG2NELFE
MGME1ENSG00000125871.9897.021201385.91350-0.627604.137302.98750HepG2RPS10
MGME1ENSG00000125871.91284.455101662.13830-0.371902.740501.94300HepG2RPS2
MGME1ENSG00000125871.9872.703601294.23960-0.5685010.963709.81460HepG2SAFB2
MGME1ENSG00000125871.9949.689901303.08900-0.456402.593301.94000HepG2SF3A3
MGME1ENSG00000125871.9730.522101298.63100-0.8300011.6557010.30010HepG2SF3B1
MGME1ENSG00000125871.91268.586802201.83160-0.7955028.1417026.36350HepG2SLBP
MGME1ENSG00000125871.91017.854201438.14840-0.498703.236702.19190HepG2SMNDC1
MGME1ENSG00000125871.91666.386902476.08550-0.5713014.8213013.90630HepG2SRFBP1
MGME1ENSG00000125871.92506.308201584.842400.6611018.5324017.53610HepG2SRSF1
MGME1ENSG00000125871.91713.386502267.30650-0.404107.168006.22540HepG2SRSF5
MGME1ENSG00000125871.91092.551501440.74890-0.399105.819004.87050HepG2SRSF7
MGME1ENSG00000125871.91673.808302149.87200-0.361105.908605.21290HepG2SSB
MGME1ENSG00000125871.9877.268401519.58080-0.792608.187607.12440HepG2SUPV3L1
MGME1ENSG00000125871.91815.482601424.539800.349804.257603.58490HepG2TAF15
MGME1ENSG00000125871.9909.759901278.82650-0.491304.578603.67760HepG2TARDBP
MGME1ENSG00000125871.9719.303901018.57020-0.501903.290902.20880HepG2TFIP11
MGME1ENSG00000125871.91035.009101424.76430-0.461107.677206.81500HepG2TRIM56
MGME1ENSG00000125871.91745.837002243.42930-0.361803.842202.79490HepG2TUFM
MGME1ENSG00000125871.91602.566902374.62780-0.567305.617304.39680HepG2UBE2L3
MGME1ENSG00000125871.9942.422801155.64150-0.294203.162702.42680HepG2UPF1
MGME1ENSG00000125871.9933.376601187.83200-0.347803.799502.59030HepG2UTP18
MGME1ENSG00000125871.91521.770001249.688000.284103.716302.95720HepG2ZC3H8
MGME1ENSG00000125871.9810.095401270.98330-0.6498014.9715013.95010HepG2ZNF622
MGME1ENSG00000125871.91023.340701409.59760-0.462002.870901.54780HepG2ZRANB2
MGME1ENSG00000125871.9629.47010854.95240-0.441704.736404.02760K562AGGF1
MGME1ENSG00000125871.9666.00330889.60990-0.417603.257402.54690K562AKAP8L
MGME1ENSG00000125871.9858.578501252.25930-0.544505.346804.57730K562AQR
MGME1ENSG00000125871.92171.683601786.899000.281303.083702.05550K562CELF1
MGME1ENSG00000125871.9375.96890560.61360-0.576404.921303.47620K562DDX3X
MGME1ENSG00000125871.91280.296601081.449900.243402.228301.63350K562DDX47
MGME1ENSG00000125871.91140.238701453.48480-0.350203.581502.51390K562EIF4G2
MGME1ENSG00000125871.9741.61710609.094400.283902.025201.49170K562FXR1
MGME1ENSG00000125871.91005.421001305.08650-0.376302.240601.55690K562GRSF1
MGME1ENSG00000125871.9682.74190857.61510-0.329002.443401.43600K562HNRNPA1
MGME1ENSG00000125871.9436.18030675.01330-0.630005.685104.85990K562HNRNPC
MGME1ENSG00000125871.9661.98150949.75330-0.520806.170004.82360K562HNRNPU
MGME1ENSG00000125871.9566.01720788.01260-0.477402.908401.84900K562IGF2BP2
MGME1ENSG00000125871.9551.89330746.74010-0.436204.485503.47720K562MTPAP
MGME1ENSG00000125871.9459.84580742.59800-0.691402.906401.88460K562PABPN1
MGME1ENSG00000125871.91266.65290839.315400.593605.309004.15260K562PCBP3
MGME1ENSG00000125871.91090.80290643.775400.760704.920403.84770K562POLR2G
MGME1ENSG00000125871.9534.80580882.29800-0.722307.752006.88980K562PUS1
MGME1ENSG00000125871.9687.69650859.62580-0.321902.540701.96890K562RBM15
MGME1ENSG00000125871.9908.544701237.38970-0.445703.614301.76590K562RBM17
MGME1ENSG00000125871.9589.11190771.63980-0.389402.759401.92090K562RBM22
MGME1ENSG00000125871.9387.58530523.33530-0.433202.514101.54820K562SRFBP1
MGME1ENSG00000125871.91065.36120788.852900.433404.151803.29270K562SRSF1
MGME1ENSG00000125871.9538.17560798.38890-0.569004.895903.94070K562TARDBP
MGME1ENSG00000125871.9580.21770770.13140-0.408503.324002.41600K562TIA1
MGME1ENSG00000125871.9875.17870628.113500.478502.342001.60390K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MGME1 is not available on ENCORE database.





17 RBPs can affect the splicing of MGME1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179507731796880817968941-0.102000.001490.08030excludedHepG2RBM22
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179510131796880817968941-0.155000.000580.02051excludedK562AKAP8L
SEMGME1ENSG00000125871.9chr20+179688081796894117956518179565461797058117970874-0.065000.001540.01752excludedK562AQR
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179510131796880817968941-0.178000.000190.00430excludedK562PUS1
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179507731796880817968941-0.194000.000020.02104excludedHepG2UPF1
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179507731796880817968941-0.179000.000000.00119excludedHepG2DDX6
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179507731796880817968941-0.112000.000130.01337excludedHepG2HNRNPL
SEMGME1ENSG00000125871.9chr20+1795632617956546179508211795101317968808179689410.064000.002320.04942includedHepG2SRSF1
SEMGME1ENSG00000125871.9chr20+1796880817968941179506991795101317970581179708740.119000.001640.09037includedK562HNRNPUL1
SEMGME1ENSG00000125871.9chr20+1795334917953394179506991795101317956326179565460.150000.000320.02870includedHepG2TIAL1
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179510131796880817968941-0.181000.000930.03250excludedK562UTP18
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179510131796880817968941-0.124000.003290.06689excludedK562RBM15
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179510131796880817968941-0.213000.000010.00089excludedK562AGGF1
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179507731796880817968941-0.165000.000010.00479excludedHepG2SMNDC1
SEMGME1ENSG00000125871.9chr20+1796880817968941179563261795654617970581179708740.058000.000070.00506includedHepG2HNRNPU
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179507731796880817968941-0.149000.000010.00463excludedHepG2XRCC6
SEMGME1ENSG00000125871.9chr20+179563261795654617950443179510131796880817968941-0.244000.000340.00765excludedK562HNRNPC
A3SSMGME1ENSG00000125871.9chr20+1796878617968941179688081796894117956326179565460.181000.000000.00000longerK562AQR
MXEMGME1ENSG00000125871.9chr20+17950443179507731795082117951013179497151794978417968808179689410.096000.001440.031371includedHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MGME1 is not avaliable on ENCORE database.