MAP4K5

General Information

Gene Name       : MAP4K5
Gene ID             : ENSG00000012983.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MAP4K5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAP4K5ENSG00000012983.1123.1919.4321.31ENCSR000AEF
HepG2MAP4K5ENSG00000012983.1110.8220.8715.85ENCSR985KAT
K562MAP4K5ENSG00000012983.1110.9712.1111.54ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAP4K5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAP4K5 RNA is bound by 16 proteins.  







eCLIP assay for MAP4K5 is not avaliable on ENCORE database.





16 proteins are bound to MAP4K5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr145088552950885553-3'-UTR,intron-Distal5.062463.74454K562ZC3H11A
chr145094283250942935-3'-UTR,CDS,intron-Distal,intron-Proximal5.401036.71458K562EFTUD2
chr145093330250933350-3'-UTR,CDS,intron-Distal3.638086.36847HepG2BCLAF1
chr145088548350885517-3'-UTR,intron-Distal4.975724.95154K562ZC3H11A
chr145094298150943022-3'-UTR,CDS,intron-Distal,intron-Proximal4.665304.78529HepG2BCLAF1
chr145088547950885572-3'-UTR,intron-Distal3.372953.13224HepG2ZC3H11A
chr145099916950999331-5'-UTR,intron-Distal,intron-Proximal4.038407.88206HepG2NCBP2
chr145099884350998878-5'-UTR,intron-Distal,intron-Proximal3.488706.51082HepG2PPIG
chr145099919850999254-5'-UTR,intron-Distal,intron-Proximal3.936754.82666HepG2DDX3X
chr145099867950998869-5'-UTR,CDS,intron-Distal,intron-Proximal3.880003.05298K562GRWD1
chr145099871750998877-5'-UTR,CDS,intron-Distal,intron-Proximal4.497665.42152HepG2GRWD1
chr145090655850906744-CDS,intron-Distal,intron-Proximal5.042987.79404K562PRPF8
chr145094907250949191-CDS,intron-Distal,intron-Proximal4.484249.71879K562SF3B4
chr145091040950910483-CDS,intron-Distal,intron-Proximal5.498737.70650HepG2PRPF8
chr145095230850952360-CDS,intron-Distal3.887075.37538K562ZNF622
chr145092315550923236-CDS,intron-Distal,intron-Proximal3.466223.28806K562KHSRP
chr145095230750952361-CDS,intron-Distal,intron-Proximal3.783829.08790HepG2BCLAF1
chr145095226150952297-CDS,intron-Distal,intron-Proximal4.140146.80869K562AQR
chr145091186450911912-CDS,intron-Distal3.053363.84771K562ZNF622
chr145090945450909509-CDS,intron-Distal4.452703.53690K562ZNF622
chr145099866050998707-CDS,intron-Distal3.308413.64266HepG2PPIG
chr145091549150915531-CDS,intron-Distal,intron-Proximal3.395613.61259K562ZNF622
chr145092934650929411-CDS,intron-Distal,intron-Proximal4.469283.86479HepG2PRPF8
chr145095229450952307-CDS,intron-Distal,intron-Proximal4.366356.65960HepG2BCLAF1
chr145094907850949117-CDS,intron-Distal,intron-Proximal4.513767.09561HepG2BCLAF1
chr145090419250904239-CDS,intron-Distal,intron-Proximal3.872824.93978HepG2BCLAF1
chr145094911750949136-CDS,intron-Distal,intron-Proximal3.656345.15500HepG2BCLAF1
chr145098803950988109-intron-Distal3.886483.48210HepG2HNRNPL
chr145095224850952261-intron-Distal,intron-Proximal4.307387.79506K562AQR
chr145090665350906725-intron-Distal,intron-Proximal4.993747.61259K562KHSRP
chr145095677650956860-intron-Distal4.140034.04407K562HNRNPL
chr145098462750984739-intron-Distal3.869005.75173HepG2QKI
chr145095220350952275-intron-Distal,intron-Proximal3.515954.35635K562PRPF8
chr145091559350915668-intron-Distal,intron-Proximal4.6477413.46441HepG2U2AF2
chr145089525850895378-intron-Distal,intron-Proximal4.378393.89565K562PRPF8
chr145088690950886983-intron-Distal3.318504.10408K562KHSRP
chr145088683850886909-intron-Distal3.901583.42844K562KHSRP
chr145090660450906653-intron-Distal,intron-Proximal3.157534.35941K562KHSRP
chr145091690050916975-intron-Distal4.499095.77165HepG2TIAL1
chr145090538650905510-intron-Distal3.154404.96160K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAP4K5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAP4K5 is not available on ENCORE database.

  • 70 RBPs can affect the levels of MAP4K5.  








The Knockdown/knockout RNA-Seq assay for MAP4K5 is not available on ENCORE database.





70 RBPs can affect the gene expression of MAP4K5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAP4K5ENSG00000012983.71430.35630955.802000.5815011.9336010.86020HepG2ACO1
MAP4K5ENSG00000012983.7688.62190882.87270-0.358502.334501.41700HepG2ADAR
MAP4K5ENSG00000012983.7953.071401315.02280-0.464406.757105.75800HepG2AUH
MAP4K5ENSG00000012983.71196.750501530.19310-0.354602.321601.76820HepG2BOP1
MAP4K5ENSG00000012983.7544.15940829.21990-0.607705.070304.04150HepG2CIRBP
MAP4K5ENSG00000012983.7728.38600955.69810-0.391904.969804.12640HepG2CKAP4
MAP4K5ENSG00000012983.7972.258301369.24610-0.494009.748508.49240HepG2DAZAP1
MAP4K5ENSG00000012983.7647.87060856.51020-0.402803.078502.36570HepG2DDX21
MAP4K5ENSG00000012983.7792.083101010.46170-0.351302.097601.54480HepG2DDX3X
MAP4K5ENSG00000012983.7575.12180868.02500-0.593904.247303.49510HepG2DDX6
MAP4K5ENSG00000012983.7739.58110889.03930-0.265502.061901.44500HepG2DNAJC21
MAP4K5ENSG00000012983.7642.06450881.12190-0.456606.395205.46260HepG2DNAJC2
MAP4K5ENSG00000012983.7552.60800739.32830-0.420002.456301.59960HepG2EIF3D
MAP4K5ENSG00000012983.7663.22500922.14160-0.475503.099002.42340HepG2EIF4A3
MAP4K5ENSG00000012983.71712.39650897.850300.931407.558506.45290HepG2EIF4B
MAP4K5ENSG00000012983.71907.294801312.011500.539604.493703.52920HepG2FIP1L1
MAP4K5ENSG00000012983.7801.71480551.691800.539104.921403.88790HepG2FUBP3
MAP4K5ENSG00000012983.7939.612001592.61700-0.761306.930905.94720HepG2GPKOW
MAP4K5ENSG00000012983.7694.77860897.55580-0.369402.790102.14050HepG2HNRNPA1
MAP4K5ENSG00000012983.7911.661301270.16340-0.478407.358506.25990HepG2HNRNPF
MAP4K5ENSG00000012983.7962.083201247.32560-0.374603.577102.81750HepG2HNRNPL
MAP4K5ENSG00000012983.7702.53560991.74390-0.497406.878905.96120HepG2HNRNPU
MAP4K5ENSG00000012983.7749.481501250.74330-0.7388011.9874010.58660HepG2IGF2BP1
MAP4K5ENSG00000012983.7571.74690873.78740-0.6119010.221008.37890HepG2KIF1C
MAP4K5ENSG00000012983.71246.994101941.26140-0.638505.639604.44010HepG2LARP4
MAP4K5ENSG00000012983.71251.79790935.957800.419402.721002.09470HepG2MATR3
MAP4K5ENSG00000012983.7983.806501549.79590-0.655604.516103.25750HepG2MTPAP
MAP4K5ENSG00000012983.7924.808001357.73330-0.554005.734604.64350HepG2NOL12
MAP4K5ENSG00000012983.71029.97790805.110000.355303.943003.24520HepG2PCBP1
MAP4K5ENSG00000012983.71190.86360819.254000.539508.597007.74280HepG2PTBP1
MAP4K5ENSG00000012983.7874.292301296.03210-0.567906.833805.95310HepG2PUF60
MAP4K5ENSG00000012983.71711.870201374.771300.316302.914402.22690HepG2PUM2
MAP4K5ENSG00000012983.71079.51390887.220100.282902.273701.69760HepG2QKI
MAP4K5ENSG00000012983.72042.57940956.393101.094609.552108.29660HepG2RAVER1
MAP4K5ENSG00000012983.71888.147701261.951300.5812010.560209.69200HepG2RBM22
MAP4K5ENSG00000012983.7974.23440805.229000.274801.879601.31480HepG2RBM25
MAP4K5ENSG00000012983.7456.38130872.85070-0.935508.939707.04440HepG2RCC2
MAP4K5ENSG00000012983.71109.34890911.730700.282902.652402.12050HepG2NELFE
MAP4K5ENSG00000012983.71102.49700849.190200.376504.331403.58320HepG2RECQL
MAP4K5ENSG00000012983.71039.48210723.783900.522104.337703.37710HepG2RRP9
MAP4K5ENSG00000012983.71037.155201504.42220-0.536603.881603.05790HepG2SF3B1
MAP4K5ENSG00000012983.71068.75180852.905200.325403.305302.66540HepG2SF3B4
MAP4K5ENSG00000012983.71040.843701242.58900-0.255602.979502.25400HepG2SLBP
MAP4K5ENSG00000012983.72500.864201425.316200.8110028.4730027.30600HepG2SRFBP1
MAP4K5ENSG00000012983.71504.19980890.266300.7566017.6235016.64620HepG2SRSF1
MAP4K5ENSG00000012983.71540.397401279.582400.267502.703502.08280HepG2SRSF5
MAP4K5ENSG00000012983.7825.555601247.91100-0.5961010.841709.61950HepG2SRSF7
MAP4K5ENSG00000012983.71138.85050724.294500.6528012.5134011.48870HepG2SRSF9
MAP4K5ENSG00000012983.7983.791401237.49200-0.331003.964203.37440HepG2SSB
MAP4K5ENSG00000012983.71031.21810800.255900.365703.409502.79730HepG2TAF15
MAP4K5ENSG00000012983.7930.95930735.273300.340302.823301.97920HepG2TIA1
MAP4K5ENSG00000012983.7731.53500963.74790-0.397703.669303.11090HepG2TIAL1
MAP4K5ENSG00000012983.7837.26360972.27360-0.215701.833101.35520HepG2TRIM56
MAP4K5ENSG00000012983.71548.693501122.410100.464404.154203.39150HepG2U2AF1
MAP4K5ENSG00000012983.7551.40850928.95640-0.752502.575101.87450HepG2XRN2
MAP4K5ENSG00000012983.71065.03750844.826300.334103.945903.16800HepG2ZC3H8
MAP4K5ENSG00000012983.7984.194201166.09050-0.244702.677202.13760HepG2ZNF622
MAP4K5ENSG00000012983.7999.772601208.25150-0.273202.616302.06080K562AGGF1
MAP4K5ENSG00000012983.7864.185801226.14220-0.504704.569703.85000K562AQR
MAP4K5ENSG00000012983.71698.787601381.501800.298203.570902.84260K562DDX47
MAP4K5ENSG00000012983.7776.01320927.00980-0.256502.026901.39400K562EIF2S2
MAP4K5ENSG00000012983.7491.05710727.64550-0.567305.128904.01030K562EIF4A3
MAP4K5ENSG00000012983.71985.048601668.012400.250902.842301.89120K562EIF4G2
MAP4K5ENSG00000012983.71257.49330840.552600.581004.250703.33130K562G3BP2
MAP4K5ENSG00000012983.7799.714501235.26620-0.627307.724806.44860K562GRSF1
MAP4K5ENSG00000012983.71016.393301248.49800-0.296702.268401.32010K562HNRNPL
MAP4K5ENSG00000012983.7566.60640847.38310-0.580704.465503.26250K562HNRNPM
MAP4K5ENSG00000012983.7903.255301169.51800-0.372702.471601.70000K562PPIG
MAP4K5ENSG00000012983.71443.366801819.93470-0.334402.881902.04930K562PUF60
MAP4K5ENSG00000012983.7358.84600563.05870-0.649905.634104.21120K562RCC2
MAP4K5ENSG00000012983.7688.185301030.94720-0.583108.104406.76740K562SF3A3
MAP4K5ENSG00000012983.7664.98110874.31470-0.394803.504202.53780K562SF3B4
MAP4K5ENSG00000012983.7604.81300781.19070-0.369202.569001.56190K562SRSF4
MAP4K5ENSG00000012983.7567.68400867.07320-0.611105.715304.67720K562TARDBP
MAP4K5ENSG00000012983.71097.03310815.092300.428502.902701.77860K562U2AF1
MAP4K5ENSG00000012983.7915.785101107.87370-0.274702.711301.99930K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAP4K5 is not available on ENCORE database.





4 RBPs can affect the splicing of MAP4K5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAP4K5ENSG00000012983.7chr14-5091990750919974509154915091555050923233509233120.333000.000010.00056includedK562U2AF1
SEMAP4K5ENSG00000012983.7chr14-5091990750919974509154915091555050923233509233120.180000.004790.06721includedK562HNRNPC
A3SSMAP4K5ENSG00000012983.7chr14-5091549150915601509154915091555050923233509233120.267000.000070.00382longerK562U2AF2
A3SSMAP4K5ENSG00000012983.7chr14-5091549150915601509154915091555050923233509233120.284000.000030.00159longerHepG2U2AF2
A3SSMAP4K5ENSG00000012983.7chr14-5090167950901828509016795090178350904193509042810.086000.000910.00639longerK562AQR
A3SSMAP4K5ENSG00000012983.7chr14-5089262450892746508926245089269550895379508954720.074000.006150.03465longerK562AQR
A3SSMAP4K5ENSG00000012983.7chr14-5090419350904281509041935090425250904611509047290.126000.002340.01479longerK562AQR
A3SSMAP4K5ENSG00000012983.7chr14-5091549150915601509154915091555050923233509233120.210000.000330.01563longerHepG2U2AF1
A3SSMAP4K5ENSG00000012983.7chr14-5091549150915601509154915091555050923233509233120.280000.000070.00492longerK562U2AF1
RIMAP4K5ENSG00000012983.7chr14-5090461150904812509046115090472650904809509048120.153000.011100.08608includedHepG2U2AF1
MXEMAP4K5ENSG00000012983.7chr14-50895379508954725089590950895978508926245089269550901111509012890.245000.000280.002831includedHepG2U2AF2
MXEMAP4K5ENSG00000012983.7chr14-5088983850889894508926245089269550885242508868245089537950895472-0.215000.002060.014952includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAP4K5 is not avaliable on ENCORE database.