IRF2

General Information

Gene Name       : IRF2
Gene ID             : ENSG00000168310.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: IRF2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878IRF2ENSG00000168310.1060.8554.3757.61ENCSR000AEF
HepG2IRF2ENSG00000168310.1011.5618.1214.84ENCSR985KAT
K562IRF2ENSG00000168310.108.819.789.29ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for IRF2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • IRF2 RNA is bound by 13 proteins.  







eCLIP assay for IRF2 is not avaliable on ENCORE database.





13 proteins are bound to IRF2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr4185309305185309449-3'-UTR,intron-Distal3.278335.12480HepG2HNRNPK
chr4185309256185309404-3'-UTR,intron-Distal3.428077.83161K562ILF3
chr4185309480185309552-3'-UTR,intron-Distal6.1324523.03612K562PUM2
chr4185309236185309413-3'-UTR,intron-Distal3.217557.94935HepG2DDX59
chr4185309386185309434-3'-UTR,intron-Distal4.087329.26230HepG2PCBP2
chr4185309288185309386-3'-UTR,intron-Distal5.6026722.13633HepG2PCBP2
chr4185340653185340718-3'-UTR,CDS,intron-Distal4.305353.45943HepG2BCLAF1
chr4185311844185311961-CDS,intron-Distal,intron-Proximal3.561993.67894HepG2AQR
chr4185380297185380401-intron-Distal5.076227.87558HepG2HNRNPM
chr4185394700185394813-intron-Distal3.367527.07486HepG2NKRF
chr4185394744185394831-intron-Distal5.086738.56618HepG2CSTF2T
chr4185394674185394744-intron-Distal3.321253.69530HepG2CSTF2T
chr4185394966185395058-intron-Distal3.949953.31905K562NONO
chr4185385360185385486-intron-Distal4.1000710.48397HepG2HNRNPL
chr4185385481185385602-intron-Distal4.822427.69118K562HNRNPL
chr4185385201185385277-intron-Distal4.6338711.87188HepG2HNRNPL
chr4185385294185385360-intron-Distal3.479718.73821HepG2HNRNPL
chr4185385232185385468-intron-Distal3.737799.19663HepG2PTBP1
chr4185370280185370341-intron-Distal3.265933.42785HepG2HNRNPM
chr4185385310185385481-intron-Distal4.2125310.03443K562HNRNPL
chr4185393992185394057-intron-Distal3.636635.32871HepG2CSTF2T
chr4185394990185395075-intron-Distal3.165884.23490HepG2NKRF
chr4185385486185385579-intron-Distal5.0952117.72533HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for IRF2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for IRF2 is not available on ENCORE database.

  • 69 RBPs can affect the levels of IRF2.  








The Knockdown/knockout RNA-Seq assay for IRF2 is not available on ENCORE database.





69 RBPs can affect the gene expression of IRF2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
IRF2ENSG00000168310.6344.34840788.88830-1.1960013.0748012.00590HepG2AKAP1
IRF2ENSG00000168310.6972.85420652.751400.575604.866903.83790HepG2ASCC1
IRF2ENSG00000168310.6241.43940404.16400-0.743303.915502.79990HepG2BCCIP
IRF2ENSG00000168310.6243.81060351.21530-0.526602.201201.39890HepG2BCLAF1
IRF2ENSG00000168310.6823.14040606.196000.441303.493802.11920HepG2BUD13
IRF2ENSG00000168310.61059.44400620.154700.772508.629707.32490HepG2CIRBP
IRF2ENSG00000168310.6301.13120501.24390-0.735108.914807.85250HepG2CKAP4
IRF2ENSG00000168310.6974.81460737.852600.401702.983302.27260HepG2CPSF6
IRF2ENSG00000168310.6281.04050397.36240-0.499701.970601.30640HepG2DDX55
IRF2ENSG00000168310.6598.83020479.669800.320002.265801.64270HepG2DKC1
IRF2ENSG00000168310.6376.38990494.55900-0.393902.721502.02200HepG2DNAJC21
IRF2ENSG00000168310.6325.08900671.46860-1.046508.526407.35300HepG2EIF4B
IRF2ENSG00000168310.61226.08810739.117300.730102.926601.88100HepG2FTO
IRF2ENSG00000168310.6463.64260645.49910-0.477402.863902.18730HepG2G3BP1
IRF2ENSG00000168310.6759.82210615.171200.304602.717602.00630HepG2HNRNPF
IRF2ENSG00000168310.6393.91600653.51240-0.730306.406105.37420HepG2HNRNPK
IRF2ENSG00000168310.6332.71110563.69470-0.760607.696406.22990HepG2HNRNPM
IRF2ENSG00000168310.6757.48810605.771900.322302.360201.68930HepG2IGF2BP1
IRF2ENSG00000168310.6437.52510563.55270-0.365203.021902.25850HepG2ILF2
IRF2ENSG00000168310.6268.19310429.42800-0.679104.379402.84370HepG2LIN28B
IRF2ENSG00000168310.6274.56790422.24730-0.620902.523601.51640HepG2METAP2
IRF2ENSG00000168310.6348.76600661.19430-0.9228011.275109.75450HepG2MSI2
IRF2ENSG00000168310.6513.40850716.44640-0.480802.948902.29650HepG2NCBP2
IRF2ENSG00000168310.61072.60620707.761200.599705.743504.68690HepG2NSUN2
IRF2ENSG00000168310.61005.50450557.494500.8508016.8738015.22830HepG2PRPF4
IRF2ENSG00000168310.6527.78010679.45530-0.364403.253702.66960HepG2PTBP1
IRF2ENSG00000168310.6516.68040637.95100-0.304201.916301.35190HepG2PUM2
IRF2ENSG00000168310.6352.75380492.99210-0.482902.436101.51220HepG2RBM27
IRF2ENSG00000168310.6524.27620756.17550-0.528405.802005.06420HepG2NELFE
IRF2ENSG00000168310.6578.46870704.26200-0.283902.081201.53640HepG2RECQL
IRF2ENSG00000168310.61018.67420662.631400.620306.663505.66830HepG2RPLP0
IRF2ENSG00000168310.6439.41940707.41580-0.687008.796207.83260HepG2SF3B4
IRF2ENSG00000168310.6404.02460572.95340-0.504005.245904.40850HepG2SMN1
IRF2ENSG00000168310.6915.53100624.954800.550807.492606.77880HepG2SRFBP1
IRF2ENSG00000168310.6507.80830738.38270-0.540106.069505.43610HepG2SRSF1
IRF2ENSG00000168310.6738.37410604.371800.288802.432401.77680HepG2SRSF7
IRF2ENSG00000168310.6695.81660542.584500.358803.090502.55490HepG2SSB
IRF2ENSG00000168310.6548.24620663.67010-0.275601.870401.39280HepG2TAF15
IRF2ENSG00000168310.6478.83050609.84060-0.348902.281401.52030HepG2TIA1
IRF2ENSG00000168310.6657.29170536.063600.294001.956801.52090HepG2TIAL1
IRF2ENSG00000168310.6445.57080540.88370-0.279701.825401.34830HepG2TRIM56
IRF2ENSG00000168310.6387.13360621.89410-0.683804.427303.35180HepG2UBE2L3
IRF2ENSG00000168310.6415.31720587.37470-0.500102.515101.50770HepG2XRCC6
IRF2ENSG00000168310.6788.09990550.173400.518406.748405.77450HepG2ZC3H8
IRF2ENSG00000168310.6388.30830768.39850-0.9847020.9921019.83020HepG2ZNF622
IRF2ENSG00000168310.6715.29600529.659000.433402.908101.64740K562ABCF1
IRF2ENSG00000168310.6364.22730492.13520-0.434202.845401.58730K562APOBEC3C
IRF2ENSG00000168310.6877.67210484.432600.857309.468007.80260K562BOP1
IRF2ENSG00000168310.6351.58710215.058400.709102.343601.39130K562CCAR1
IRF2ENSG00000168310.6952.88750578.374100.720204.183802.83380K562CNOT7
IRF2ENSG00000168310.6806.98720515.090100.647606.999105.74180K562CPSF6
IRF2ENSG00000168310.61043.88560685.844700.605907.038905.50490K562CELF1
IRF2ENSG00000168310.6353.46740259.462700.446002.935401.68260K562EIF2S1
IRF2ENSG00000168310.6409.80920284.719200.525303.848503.02180K562EIF2S2
IRF2ENSG00000168310.6455.60970323.835700.492402.706401.59470K562FKBP4
IRF2ENSG00000168310.6772.05050524.093300.558803.584102.60650K562FMR1
IRF2ENSG00000168310.6669.56090444.216900.591904.376703.20230K562FTO
IRF2ENSG00000168310.6697.55590491.783800.504203.216902.36260K562GPKOW
IRF2ENSG00000168310.6890.90810518.995300.779504.562502.25530K562HNRNPA0
IRF2ENSG00000168310.6467.30110334.051500.484203.348902.16470K562HNRNPA1
IRF2ENSG00000168310.6731.64760419.923400.800905.308103.96030K562KRR1
IRF2ENSG00000168310.6627.50300480.036100.386402.459701.63840K562METAP2
IRF2ENSG00000168310.6618.53140439.136600.494105.317504.33130K562NSUN2
IRF2ENSG00000168310.6204.19250296.15700-0.536402.459301.54020K562PCBP2
IRF2ENSG00000168310.6223.89090323.35780-0.530303.226002.51570K562PTBP1
IRF2ENSG00000168310.6789.73780608.534100.375902.169701.44870K562PUF60
IRF2ENSG00000168310.6884.64200647.323700.450503.879402.59600K562PUM1
IRF2ENSG00000168310.6362.31490229.798300.656803.265701.82350K562RRP9
IRF2ENSG00000168310.6691.54240467.705800.564103.732702.59390K562SF3B1
IRF2ENSG00000168310.6651.42430456.903400.511603.419401.99940K562STAU1
IRF2ENSG00000168310.6313.16180409.73290-0.387802.215301.47960K562SYNCRIP
IRF2ENSG00000168310.6464.67150321.477500.531403.043802.05730K562TIAL1
IRF2ENSG00000168310.6694.42560465.624900.576606.872305.79680K562UPF1
IRF2ENSG00000168310.6710.15330493.904500.523803.315901.99600K562UTP3
IRF2ENSG00000168310.6587.63950398.422000.560504.783303.61710K562WDR3
IRF2ENSG00000168310.6683.29980444.263800.621005.912504.57470K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for IRF2 is not available on ENCORE database.





1 RBPs can affect the splicing of IRF2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEIRF2ENSG00000168310.6chr4-185339320185339367185320068185320233185339685185339862-0.164000.007400.07214excludedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for IRF2 is not avaliable on ENCORE database.