HMGXB3

General Information

Gene Name       : HMGXB3
Gene ID             : ENSG00000113716.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: HMGXB3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HMGXB3ENSG00000113716.1218.0420.9419.49ENCSR000AEF
HepG2HMGXB3ENSG00000113716.1215.0216.3215.67ENCSR985KAT
K562HMGXB3ENSG00000113716.1228.8827.6128.24ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HMGXB3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HMGXB3 RNA is bound by 31 proteins.  







eCLIP assay for HMGXB3 is not avaliable on ENCORE database.





31 proteins are bound to HMGXB3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5149432038149432121+3'-UTR5.463629.20661K562UPF1
chr5149420392149420442+3'-UTR,CDS4.884416.21892HepG2PPIG
chr5149425229149425300+3'-UTR,CDS,intron-Proximal4.334663.89565K562PRPF8
chr5149432063149432099+3'-UTR4.786143.88917K562DDX6
chr5149421347149421388+3'-UTR,CDS,intron-Proximal3.490503.69978K562DDX24
chr5149421347149421421+3'-UTR,CDS,intron-Proximal3.671888.51932K562ZNF622
chr5149432121149432313+3'-UTR6.2864516.89355K562UPF1
chr5149421447149421530+3'-UTR,CDS3.642984.51003HepG2PPIG
chr5149432216149432337+3'-UTR4.071933.55598HepG2ZC3H11A
chr5149432261149432327+3'-UTR3.822293.18535HepG2LSM11
chr5149432042149432125+3'-UTR4.106833.48722HepG2PRPF4
chr5149432000149432173+3'-UTR4.019907.18303HepG2GRSF1
chr5149421347149421410+3'-UTR,CDS,intron-Proximal3.476496.37739K562BUD13
chr5149425240149425291+3'-UTR,CDS,intron-Proximal5.044946.35567HepG2PRPF8
chr5149421345149421414+3'-UTR,CDS,intron-Proximal4.6441011.38699HepG2PPIG
chr5149431951149432077+3'-UTR5.7437510.53253K562ZC3H11A
chr5149432005149432124+3'-UTR4.314083.92497HepG2UPF1
chr5149432018149432144+3'-UTR5.263526.72583HepG2EIF3H
chr5149425071149425125+3'-UTR,CDS5.115828.22878K562FXR2
chr5149380603149380664+5'-UTR4.023586.04229K562RBM15
chr5149380724149380799+5'-UTR,intron-Proximal4.456115.17013K562RBM15
chr5149380367149380449+5'-UTR3.739016.05537HepG2DDX3X
chr5149380711149380786+5'-UTR,intron-Proximal5.350157.02967HepG2PRPF8
chr5149380526149380594+5'-UTR4.5082413.12854K562DHX30
chr5149380286149380456+5'-UTR3.7830812.09993K562DDX3X
chr5149380353149380434+5'-UTR3.365833.63681K562RBM15
chr5149416928149416999+CDS,intron-Distal,intron-Proximal5.2570226.06131K562AQR
chr5149406620149406736+CDS,intron-Proximal4.7334722.07985HepG2PRPF8
chr5149416499149416504+CDS,intron-Distal,intron-Proximal5.9870220.15911K562AQR
chr5149406675149406741+CDS,intron-Proximal3.573686.90700K562BUD13
chr5149429848149429945+CDS5.408349.85253K562FMR1
chr5149406267149406332+CDS,intron-Proximal4.859095.51162HepG2U2AF2
chr5149390112149390174+CDS,intron-Proximal3.020123.09884K562LIN28B
chr5149390149149390212+CDS,intron-Proximal5.257905.68502HepG2PRPF8
chr5149416952149416999+CDS,intron-Distal,intron-Proximal4.805635.07478HepG2U2AF2
chr5149384551149384599+CDS,intron-Proximal5.167366.44303K562AQR
chr5149410351149410399+CDS3.591934.41267HepG2PPIG
chr5149386133149386209+CDS3.077365.47500HepG2PPIG
chr5149389684149389826+CDS3.102864.73488HepG2GRWD1
chr5149406678149406702+CDS,intron-Proximal3.492116.51619K562AQR
chr5149412014149412062+CDS,intron-Proximal3.919425.16342K562SF3B4
chr5149406638149406741+CDS,intron-Proximal3.2039510.47025K562PRPF8
chr5149391868149391916+CDS4.148256.28735K562DDX24
chr5149428152149428210+CDS3.589475.69590K562DDX24
chr5149429838149429941+CDS4.7096412.19301K562FXR2
chr5149410280149410337+CDS,intron-Proximal4.3539418.09000K562SF3B4
chr5149391803149391875+CDS,intron-Proximal3.201934.35314HepG2U2AF2
chr5149416160149416243+CDS,intron-Distal,intron-Proximal4.230165.26108K562SF3B4
chr5149389742149389782+CDS3.045143.55800HepG2BCLAF1
chr5149429974149430012+CDS3.551074.74241K562YBX3
chr5149412016149412055+CDS,intron-Proximal3.045143.18789HepG2BCLAF1
chr5149393700149393864+intron-Distal5.1069335.82611K562QKI
chr5149416500149416544+intron-Distal,intron-Proximal4.515953.85435K562PRPF8
chr5149406741149406798+intron-Distal,intron-Proximal3.676914.95247K562PRPF8
chr5149409481149409543+intron-Distal3.023883.08258K562TIA1
chr5149398023149398075+intron-Distal,intron-Proximal4.070523.66668K562KHSRP
chr5149417910149417976+intron-Distal4.038093.90026K562KHSRP
chr5149398351149398404+intron-Distal,intron-Proximal5.378579.81815K562KHSRP
chr5149393765149393780+intron-Distal6.4102822.24150HepG2QKI
chr5149416504149416563+intron-Distal,intron-Proximal6.4395230.42534K562AQR
chr5149393704149393765+intron-Distal5.4767022.01719HepG2QKI
chr5149402396149402446+intron-Distal3.780973.45912HepG2HNRNPC
chr5149398563149398626+intron-Distal3.024253.39754K562U2AF1
chr5149398561149398629+intron-Distal3.088044.66840K562U2AF2
chr5149393780149393852+intron-Distal7.0850334.52345HepG2QKI
chr5149410462149410558+intron-Distal,intron-Proximal4.174775.85206K562EFTUD2
chr5149410252149410280+intron-Proximal4.258456.86590K562SF3B4
chr5149398310149398351+intron-Proximal3.246653.90146K562KHSRP
chr5149427321149427369+intron-Proximal4.942344.86944K562AQR
chr5149425250149425289+intron-Proximal4.846024.86944K562AQR
chr5149427118149427181+intron-Proximal5.239727.41223K562SF3B4
chr5149406702149406730+intron-Proximal4.677899.08030K562AQR
chr5149406706149406749+intron-Proximal3.639417.49348HepG2RBM22
chr5149406708149406757+intron-Proximal5.7832610.86303K562RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HMGXB3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HMGXB3 is not available on ENCORE database.

  • 74 RBPs can affect the levels of HMGXB3.  








The Knockdown/knockout RNA-Seq assay for HMGXB3 is not available on ENCORE database.





74 RBPs can affect the gene expression of HMGXB3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HMGXB3ENSG00000113716.8818.15770991.29530-0.276902.725902.12240HepG2ACO1
HMGXB3ENSG00000113716.81267.82920995.936200.348104.146603.22110HepG2AKAP8L
HMGXB3ENSG00000113716.81264.537001540.63910-0.284903.112202.39130HepG2AUH
HMGXB3ENSG00000113716.81329.53800835.789600.669608.178507.21460HepG2BOP1
HMGXB3ENSG00000113716.81034.62060803.523700.364602.361601.64270HepG2CIRBP
HMGXB3ENSG00000113716.81176.38170991.060000.247202.628301.97610HepG2CKAP4
HMGXB3ENSG00000113716.81093.76880804.520200.443002.085901.42630HepG2CNOT7
HMGXB3ENSG00000113716.81436.006101153.071400.316504.363403.46650HepG2DAZAP1
HMGXB3ENSG00000113716.81911.51100979.119900.9651014.1803012.87350HepG2DDX3X
HMGXB3ENSG00000113716.8565.27290871.31210-0.624203.010501.99220HepG2DDX59
HMGXB3ENSG00000113716.81258.65680841.207800.581304.603703.82440HepG2DDX6
HMGXB3ENSG00000113716.81577.57290808.550900.9642013.5939012.34860HepG2EIF2S1
HMGXB3ENSG00000113716.8762.29640558.159300.449603.009402.07080HepG2EIF3D
HMGXB3ENSG00000113716.81305.37710870.045700.585203.909603.09770HepG2EIF4B
HMGXB3ENSG00000113716.81153.69380901.667800.355502.263001.63490HepG2FXR1
HMGXB3ENSG00000113716.8667.02060869.72800-0.382802.219801.64300HepG2GPKOW
HMGXB3ENSG00000113716.81138.06470946.391200.266002.640901.68340HepG2HDGF
HMGXB3ENSG00000113716.8530.02340781.71920-0.560604.769903.87780HepG2HNRNPC
HMGXB3ENSG00000113716.81313.25300847.085100.632506.899905.83480HepG2HNRNPK
HMGXB3ENSG00000113716.8994.39910765.940500.376502.887101.91530HepG2HNRNPM
HMGXB3ENSG00000113716.81287.03990850.082400.598305.731304.79380HepG2IGF2BP2
HMGXB3ENSG00000113716.81085.30950906.155900.260202.782801.76360HepG2KIF1C
HMGXB3ENSG00000113716.81708.907101174.400800.541004.041003.03390HepG2LARP4
HMGXB3ENSG00000113716.81250.52110901.983400.471303.631402.88000HepG2MAGOH
HMGXB3ENSG00000113716.81242.98800907.002500.454503.085902.42270HepG2MATR3
HMGXB3ENSG00000113716.81477.43940928.343800.670306.731305.76290HepG2NCBP2
HMGXB3ENSG00000113716.81638.29110826.641600.9868014.2849012.68150HepG2PABPC4
HMGXB3ENSG00000113716.81470.21760920.972800.6747014.1128012.91310HepG2PCBP1
HMGXB3ENSG00000113716.8658.11270979.38820-0.573508.335207.09170HepG2PRPF4
HMGXB3ENSG00000113716.8902.12060620.170300.540603.898302.95840HepG2PRPF8
HMGXB3ENSG00000113716.81252.82490937.101200.418805.362804.65360HepG2PTBP1
HMGXB3ENSG00000113716.8844.504301091.46490-0.370102.967202.35340HepG2PUF60
HMGXB3ENSG00000113716.81298.984601009.695700.363404.963704.18250HepG2PUS1
HMGXB3ENSG00000113716.81429.177601014.953000.493706.300205.41280HepG2QKI
HMGXB3ENSG00000113716.81712.960901478.481800.212301.873901.42630HepG2RBM22
HMGXB3ENSG00000113716.81218.36690921.116500.403403.666502.89710HepG2RBM25
HMGXB3ENSG00000113716.8906.16360682.108300.409702.493001.48760HepG2RCC2
HMGXB3ENSG00000113716.81052.269101287.74740-0.291302.136301.52620HepG2RPLP0
HMGXB3ENSG00000113716.81043.71730751.871000.473102.453201.56340HepG2RPS10
HMGXB3ENSG00000113716.8801.22950543.120300.560805.334204.51340HepG2RPS19
HMGXB3ENSG00000113716.8822.12130691.554900.249402.061901.49260HepG2SAFB2
HMGXB3ENSG00000113716.8876.51410545.095200.685206.732405.27590HepG2SERBP1
HMGXB3ENSG00000113716.81783.006501182.171900.592804.307803.45660HepG2SF3A3
HMGXB3ENSG00000113716.81207.62650975.684700.307603.082002.46230HepG2SF3B4
HMGXB3ENSG00000113716.82180.604601669.865900.384906.907606.21530HepG2SRFBP1
HMGXB3ENSG00000113716.81307.111401018.386700.360004.372103.81070HepG2SRSF1
HMGXB3ENSG00000113716.8950.775901174.43210-0.304803.405302.64430HepG2SRSF7
HMGXB3ENSG00000113716.81015.67180828.497300.293802.959202.39270HepG2SRSF9
HMGXB3ENSG00000113716.81113.633101449.79560-0.380605.604604.92430HepG2SSB
HMGXB3ENSG00000113716.8938.52340703.116700.416502.339701.34180HepG2STIP1
HMGXB3ENSG00000113716.81465.519401225.601100.257803.046702.39970HepG2SUCLG1
HMGXB3ENSG00000113716.81010.67630809.119900.320802.030501.39750HepG2TARDBP
HMGXB3ENSG00000113716.81260.93630754.575700.7407011.3076010.41740HepG2TIAL1
HMGXB3ENSG00000113716.8958.93780761.309100.332903.434102.82080HepG2TRIM56
HMGXB3ENSG00000113716.81288.137801066.323900.272502.056501.31430HepG2TUFM
HMGXB3ENSG00000113716.81213.793501048.405300.211201.900301.30310HepG2UPF1
HMGXB3ENSG00000113716.81327.476401012.194800.391105.497204.70130HepG2UTP3
HMGXB3ENSG00000113716.81434.145501153.045800.314604.595003.93590HepG2ZNF622
HMGXB3ENSG00000113716.82050.743002553.20530-0.316202.542801.37740K562ABCF1
HMGXB3ENSG00000113716.82611.719202066.134500.338005.627404.86320K562AGGF1
HMGXB3ENSG00000113716.82996.479102149.911200.478905.997705.01190K562AKAP8L
HMGXB3ENSG00000113716.82131.861001648.723000.370703.000502.04950K562EFTUD2
HMGXB3ENSG00000113716.82037.490002346.73060-0.203902.015101.38470K562EIF2S2
HMGXB3ENSG00000113716.81700.884501364.409700.317903.412501.40680K562FUBP3
HMGXB3ENSG00000113716.82116.863601504.049500.493008.827807.82040K562FXR1
HMGXB3ENSG00000113716.8606.708001093.72620-0.850205.954404.83020K562G3BP2
HMGXB3ENSG00000113716.8930.755501573.57160-0.7576011.9992010.82880K562HNRNPC
HMGXB3ENSG00000113716.82090.206602445.17870-0.226302.208501.41190K562HNRNPU
HMGXB3ENSG00000113716.81826.411802488.39730-0.446204.582403.56380K562HSPD1
HMGXB3ENSG00000113716.82701.577302281.577000.243702.174101.45400K562KIF1C
HMGXB3ENSG00000113716.83033.938902555.944800.247202.223301.42310K562MBNL1
HMGXB3ENSG00000113716.82331.638701791.533600.380002.364901.56420K562NAA15
HMGXB3ENSG00000113716.81827.202201321.434200.467404.076402.88310K562PCBP2
HMGXB3ENSG00000113716.82035.914901604.403300.343502.642801.90950K562PRPF8
HMGXB3ENSG00000113716.83380.405604090.87660-0.275202.804301.72830K562PUM1
HMGXB3ENSG00000113716.83409.889304008.44780-0.233302.618701.68380K562PUM2
HMGXB3ENSG00000113716.82911.796702132.089200.449504.643803.96360K562PUS1
HMGXB3ENSG00000113716.82926.761502077.426900.494408.972107.92950K562RBM15
HMGXB3ENSG00000113716.81784.975001383.332200.367703.002802.12370K562RBM22
HMGXB3ENSG00000113716.8816.984101094.34110-0.421703.371002.48730K562U2AF2
HMGXB3ENSG00000113716.82617.147603130.57480-0.258402.122901.37710K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HMGXB3 is not available on ENCORE database.





8 RBPs can affect the splicing of HMGXB3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHMGXB3ENSG00000113716.8chr5+1494093551494094501494065821494066801494103031494104020.201000.000090.00281includedK562SRSF1
SEHMGXB3ENSG00000113716.8chr5+149416198149416500149412016149412166149420310149420442-0.150000.000290.00431excludedK562AQR
SEHMGXB3ENSG00000113716.8chr5+149401371149401535149398128149398260149403824149404243-0.077000.000890.06429excludedHepG2DDX3X
SEHMGXB3ENSG00000113716.8chr5+149389673149390171149386035149386210149391817149391916-0.095000.002830.03990excludedK562PUS1
SEHMGXB3ENSG00000113716.8chr5+149409403149409450149406582149406680149410303149410402-0.088000.001530.05184excludedK562HNRNPU
SEHMGXB3ENSG00000113716.8chr5+149389673149390171149386035149386210149391817149391916-0.135000.000050.04358excludedK562SLBP
SEHMGXB3ENSG00000113716.8chr5+1493896731493901711493860351493862101493918171493919160.138000.000190.01104includedK562PTBP1
SEHMGXB3ENSG00000113716.8chr5+149389673149390171149386035149386210149391817149391916-0.096000.002580.04168excludedK562HNRNPC
A3SSHMGXB3ENSG00000113716.8chr5+1494280911494282481494281311494282481494271681494273200.075000.000010.00006longerK562AQR
A3SSHMGXB3ENSG00000113716.8chr5+1493860171493862101493860351493862101493844131493845520.070000.006190.03486longerK562AQR
A3SSHMGXB3ENSG00000113716.8chr5+1494119891494121661494120161494121661494103031494104020.053000.000390.00297longerK562AQR
A3SSHMGXB3ENSG00000113716.8chr5+1494271681494273201494271861494273201494251941494252480.106000.000030.00029longerK562AQR
A3SSHMGXB3ENSG00000113716.8chr5+1493896251493897191493896731493897191493860351493862100.159000.000000.00000longerK562AQR
MXEHMGXB3ENSG00000113716.8chr5+149403824149404243149406236149406444149398128149398260149410303149410402-0.097000.006850.046652includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HMGXB3 is not avaliable on ENCORE database.