HARS

General Information

Gene Name       : HARS
Gene ID             : ENSG00000170445.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: HARS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HARSENSG00000170445.1351.7853.5952.69ENCSR000AEF
HepG2HARSENSG00000170445.1360.7257.1258.92ENCSR985KAT
K562HARSENSG00000170445.1361.4257.0259.22ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HARS is not avaliable on ENCORE database.



Proteins bound to RNA
  • HARS RNA is bound by 14 proteins.  







eCLIP assay for HARS is not avaliable on ENCORE database.





14 proteins are bound to HARS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5140053626140053738-3'-UTR,intron-Distal,intron-Proximal3.709483.99895HepG2SUB1
chr5140053832140053907-3'-UTR,CDS,intron-Distal3.403434.62864K562ZNF622
chr5140053708140053785-3'-UTR,intron-Distal,intron-Proximal3.991313.12746HepG2GRWD1
chr5140053580140053646-3'-UTR,intron-Distal3.091743.10464K562IGF2BP2
chr5140053738140053806-3'-UTR,intron-Distal,intron-Proximal4.086925.79513HepG2SUB1
chr5140062702140062781-3'-UTR,5'-UTR,CDS,intron-Distal3.916164.13746HepG2PPIG
chr5140053834140053896-3'-UTR,CDS,intron-Distal3.843746.41974HepG2PPIG
chr5140070455140070532-5'-UTR,CDS,intron-Distal,intron-Proximal3.118983.73997K562ZNF622
chr5140070438140070518-5'-UTR,CDS,intron-Distal,intron-Proximal3.644584.40383K562UCHL5
chr5140070360140070455-5'-UTR,CDS,intron-Distal,intron-Proximal4.033163.18234K562BUD13
chr5140056657140056700-CDS,intron-Distal3.107783.73413HepG2PPIG
chr5140056910140057008-CDS,intron-Distal,intron-Proximal4.2353712.12223HepG2PPIG
chr5140054556140054621-CDS,intron-Distal,intron-Proximal5.0339311.43008HepG2PRPF8
chr5140054289140054411-CDS,intron-Distal,intron-Proximal4.356613.39686HepG2G3BP1
chr5140056382140056473-CDS,intron-Distal3.599063.05298K562GRWD1
chr5140056958140057004-CDS,intron-Distal3.434833.95937K562UCHL5
chr5140057438140057518-CDS,intron-Distal,intron-Proximal4.1274714.10710HepG2PRPF8
chr5140054588140054663-CDS,intron-Distal,intron-Proximal3.305334.45064HepG2GRWD1
chr5140058540140058591-CDS,intron-Distal,intron-Proximal3.127143.18246K562PRPF8
chr5140054263140054364-CDS,intron-Distal,intron-Proximal4.904325.23259HepG2BCLAF1
chr5140056233140056337-CDS,intron-Distal,intron-Proximal3.509053.77473HepG2PABPN1
chr5140056368140056480-CDS,intron-Distal,intron-Proximal3.238704.06531HepG2GRWD1
chr5140056199140056262-CDS,intron-Distal,intron-Proximal4.249335.05356HepG2PRPF8
chr5140054650140054720-CDS,intron-Distal,intron-Proximal3.072655.41277K562UCHL5
chr5140054269140054356-CDS,intron-Distal3.874304.76274K562UCHL5
chr5140054306140054409-CDS,intron-Distal3.287817.16988HepG2PPIG
chr5140056916140056987-CDS,intron-Distal3.009633.19733K562ZNF622
chr5140054369140054411-CDS,intron-Distal,intron-Proximal4.955734.75872K562DDX24
chr5140054670140054720-CDS,intron-Distal,intron-Proximal4.321863.99014HepG2PABPN1
chr5140056239140056271-CDS,intron-Distal3.778323.01428K562UCHL5
chr5140057432140057463-intron-Distal,intron-Proximal4.609974.45472HepG2RBM22
chr5140057006140057056-intron-Distal,intron-Proximal4.941488.37417HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HARS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HARS is not available on ENCORE database.

  • 67 RBPs can affect the levels of HARS.  








The Knockdown/knockout RNA-Seq assay for HARS is not available on ENCORE database.





67 RBPs can affect the gene expression of HARS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HARSENSG00000170445.81625.843101132.770800.5212010.600509.57090HepG2ACO1
HARSENSG00000170445.82554.148201289.483600.9859013.5095012.42620HepG2AKAP1
HARSENSG00000170445.81561.71750942.536800.7284010.236409.18050HepG2BOP1
HARSENSG00000170445.81409.139801132.569800.315104.366603.56760HepG2CKAP4
HARSENSG00000170445.81148.62740794.963100.530902.829402.05520HepG2CNOT7
HARSENSG00000170445.82594.691901455.515800.8339025.1631023.62660HepG2CELF1
HARSENSG00000170445.81638.775601108.886800.563405.134604.12120HepG2DDX55
HARSENSG00000170445.81488.945701061.209400.488503.585102.88950HepG2DDX6
HARSENSG00000170445.81538.600601097.565700.487202.978802.26650HepG2EIF4B
HARSENSG00000170445.81511.291201106.959600.449104.915703.80610HepG2EWSR1
HARSENSG00000170445.81529.898201139.565600.424903.084702.27630HepG2FIP1L1
HARSENSG00000170445.81445.215901022.399700.499203.065901.89080HepG2FUS
HARSENSG00000170445.81181.418201416.33940-0.261602.806202.08370HepG2HNRNPF
HARSENSG00000170445.8583.79110936.13270-0.681306.442805.52730HepG2HNRNPLL
HARSENSG00000170445.81112.35860921.994900.270702.681302.08430HepG2HNRNPU
HARSENSG00000170445.81065.327601394.68610-0.388604.060603.19700HepG2IGF2BP1
HARSENSG00000170445.81137.38680941.786100.272203.199502.41640HepG2ILF2
HARSENSG00000170445.81820.838101144.197400.670206.617705.67430HepG2MATR3
HARSENSG00000170445.81017.32270697.594700.544202.788701.73270HepG2METAP2
HARSENSG00000170445.81179.50300922.358300.354702.957402.12210HepG2MSI2
HARSENSG00000170445.8679.38990954.63650-0.490702.423301.52120HepG2MTPAP
HARSENSG00000170445.8544.89850830.02840-0.607205.166204.15750HepG2NSUN2
HARSENSG00000170445.81078.77850912.608900.241202.097001.35210HepG2PARN
HARSENSG00000170445.81380.800601072.702600.364204.866704.09710HepG2PCBP1
HARSENSG00000170445.8774.41810935.97900-0.273402.346601.62770HepG2PRPF4
HARSENSG00000170445.82177.483501572.568000.4694011.8688010.82120HepG2PUM1
HARSENSG00000170445.81891.13260933.750901.018008.314407.13440HepG2RAVER1
HARSENSG00000170445.81410.734101156.814200.286202.395401.59140HepG2RBM15
HARSENSG00000170445.82677.225501627.049200.7184011.4490010.54810HepG2RBM22
HARSENSG00000170445.8846.87700648.613400.384702.909802.28240HepG2RPS19
HARSENSG00000170445.81124.16620846.416400.409302.891702.09060HepG2RRP9
HARSENSG00000170445.81608.746201225.668200.392302.150901.55530HepG2SF3A3
HARSENSG00000170445.81377.972101136.370500.278003.004602.39200HepG2SF3B4
HARSENSG00000170445.81107.190001420.44680-0.359405.231204.31640HepG2SLBP
HARSENSG00000170445.81210.96690957.503800.338704.783903.97570HepG2SMN1
HARSENSG00000170445.82818.320701837.685100.6168018.1532017.16840HepG2SRFBP1
HARSENSG00000170445.81789.893801186.161300.5935013.0472012.18470HepG2SRSF1
HARSENSG00000170445.81982.688901462.667700.438807.887606.90140HepG2SRSF5
HARSENSG00000170445.81183.37640965.036800.294203.392002.79320HepG2SRSF9
HARSENSG00000170445.81334.957601595.53340-0.257202.951202.42550HepG2SSB
HARSENSG00000170445.82312.314501663.439800.4751011.3616010.24630HepG2SUCLG1
HARSENSG00000170445.81029.53210739.971200.476303.543202.43190HepG2TFIP11
HARSENSG00000170445.81085.04050903.900500.263402.542501.99730HepG2TRIM56
HARSENSG00000170445.81427.26840974.863300.549905.620404.74130HepG2U2AF1
HARSENSG00000170445.82122.166901531.933000.470103.882202.88330HepG2UBE2L3
HARSENSG00000170445.81416.025501117.268500.341804.130502.88250HepG2UTP18
HARSENSG00000170445.81801.859701049.437200.7798021.0036019.58430HepG2UTP3
HARSENSG00000170445.82035.152101195.470500.7675027.2438025.97840HepG2ZNF622
HARSENSG00000170445.81388.167001099.271200.336502.759401.58260K562AARS
HARSENSG00000170445.82320.524103071.22910-0.404404.856302.20510K562AUH
HARSENSG00000170445.8514.12380716.11980-0.478103.061801.94370K562CCAR1
HARSENSG00000170445.84213.768503619.984300.219002.272601.38820K562CELF1
HARSENSG00000170445.8738.604601039.05240-0.492405.137203.65600K562DDX3X
HARSENSG00000170445.82351.652501992.321600.239102.936702.26670K562DDX47
HARSENSG00000170445.81735.838202099.44030-0.274403.098402.34430K562EIF2S2
HARSENSG00000170445.81320.35330987.523700.418904.978603.92700K562EIF3G
HARSENSG00000170445.8539.26050965.04410-0.8396010.329708.62310K562FMR1
HARSENSG00000170445.8634.29540818.00830-0.367002.157201.35480K562FTO
HARSENSG00000170445.81961.669701128.926800.7970019.9663018.45360K562FXR1
HARSENSG00000170445.8968.855601337.22510-0.464903.829102.11170K562GEMIN5
HARSENSG00000170445.82283.661202797.79890-0.292902.664001.92140K562GRSF1
HARSENSG00000170445.81320.126401799.23000-0.446703.016502.14790K562PCBP3
HARSENSG00000170445.81606.870101246.959900.365703.717502.95880K562PTBP1
HARSENSG00000170445.82780.814303347.91220-0.267803.175602.14790K562PUM2
HARSENSG00000170445.81463.640301792.60050-0.292503.407202.50740K562SF3A3
HARSENSG00000170445.81888.487201222.466600.627309.762908.44810K562SRSF1
HARSENSG00000170445.8968.213101329.91610-0.457903.924102.68930K562UCHL5
HARSENSG00000170445.81601.393001926.26970-0.266503.495402.69410K562UPF1
HARSENSG00000170445.81360.131301648.24850-0.277202.300101.50040K562WDR3
HARSENSG00000170445.82320.157402921.87280-0.332703.232702.29160K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HARS is not available on ENCORE database.





9 RBPs can affect the splicing of HARS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHARSENSG00000170445.8chr5-140059293140059468140057492140057600140062684140062804-0.260000.000050.00173excludedK562SF3B4
SEHARSENSG00000170445.8chr5-140057492140057600140057239140057338140058586140058712-0.232000.000000.00000excludedHepG2U2AF1
SEHARSENSG00000170445.8chr5-140057492140057600140057239140057338140058586140058712-0.266000.000000.00000excludedHepG2U2AF2
SEHARSENSG00000170445.8chr5-140059372140059468140057492140057600140062684140062804-0.211000.000610.03169excludedHepG2SF3B4
A3SSHARSENSG00000170445.8chr5-1400542631400544971400542631400544101400546011400547180.058000.000000.00000longerK562AQR
A3SSHARSENSG00000170445.8chr5-1400565731400567771400565731400567011400569111400570050.073000.000000.00000longerK562AQR
A3SSHARSENSG00000170445.8chr5-1400574921400576841400574921400576001400585861400587120.177000.000000.00000longerK562AQR
A3SSHARSENSG00000170445.8chr5-1400546011400547811400546011400547181400562381400564810.106000.000000.00000longerK562AQR
A3SSHARSENSG00000170445.8chr5-1400569111400570421400569111400570051400572391400587120.093000.000000.00000longerK562AQR
A5SSHARSENSG00000170445.8chr5-140058586140058712140058646140058712140057492140057600-0.297000.000000.00153shorterK562RBM22
A5SSHARSENSG00000170445.8chr5-140058586140058712140058646140058712140057492140057600-0.450000.000000.00000shorterHepG2RBM22
A5SSHARSENSG00000170445.8chr5-140058586140058712140058646140058712140057492140057600-0.235000.000850.05089shorterHepG2SRSF1
MXEHARSENSG00000170445.8chr5-140057239140057338140057492140057600140056911140057005140058586140058712-0.118000.006150.083332includedHepG2U2AF1
MXEHARSENSG00000170445.8chr5-1400574921400576001400626841400628041400572391400573381400704391400705290.157000.000170.042141includedK562WDR43
MXEHARSENSG00000170445.8chr5-140057129140057338140057492140057600140056911140057005140058586140058712-0.060000.000170.001932includedK562AQR
MXEHARSENSG00000170445.8chr5-1400574921400576001400626841400628041400572391400573381400704391400705290.275000.000000.000001includedHepG2U2AF2
MXEHARSENSG00000170445.8chr5-140057239140057338140057492140057600140056911140057005140058586140058712-0.202000.000000.000032includedHepG2U2AF2
MXEHARSENSG00000170445.8chr5-1400574921400576001400626841400628041400572391400573381400704391400705290.177000.002630.082251includedK562SAFB
MXEHARSENSG00000170445.8chr5-1400574921400576001400626841400628041400572391400573381400704391400705290.107000.003070.046531includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HARS is not avaliable on ENCORE database.