FBXW11

General Information

Gene Name       : FBXW11
Gene ID             : ENSG00000072803.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: FBXW11)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXW11ENSG00000072803.1740.3731.9036.13ENCSR000AEF
HepG2FBXW11ENSG00000072803.1724.6032.3328.46ENCSR985KAT
K562FBXW11ENSG00000072803.1715.1316.6815.91ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXW11 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXW11 RNA is bound by 32 proteins.  







eCLIP assay for FBXW11 is not avaliable on ENCORE database.





32 proteins are bound to FBXW11 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5171290063171290111-3'-UTR,intron-Distal5.656019.77446HepG2FUBP3
chr5171295734171295798-3'-UTR,CDS,intron-Distal,intron-Proximal3.889133.02250K562YBX3
chr5171288754171288842-3'-UTR,intron-Distal3.933945.95831HepG2ZC3H11A
chr5171290111171290186-3'-UTR,intron-Distal5.8469720.77588HepG2FUBP3
chr5171289030171289072-3'-UTR,intron-Distal3.077513.07984HepG2FUBP3
chr5171289332171289379-3'-UTR,intron-Distal4.690134.85237K562UPF1
chr5171290290171290401-3'-UTR,intron-Distal5.7403173.12349K562PUM2
chr5171337575171337653-3'-UTR,CDS,intron-Distal,intron-Proximal3.885876.85451K562YBX3
chr5171289223171289285-3'-UTR,intron-Distal4.141874.67162K562FAM120A
chr5171326890171326968-3'-UTR,CDS,intron-Distal,intron-Proximal3.970443.20743HepG2PPIG
chr5171290292171290366-3'-UTR,intron-Distal3.606376.25768HepG2FUBP3
chr5171289973171290015-3'-UTR,intron-Distal4.505625.23751K562TIA1
chr5171288772171288834-3'-UTR,intron-Distal5.1382411.15990K562PUM2
chr5171289226171289276-3'-UTR,intron-Distal5.5706810.81337K562UPF1
chr5171288839171288889-3'-UTR,intron-Distal5.046036.43721K562PUM2
chr5171289247171289339-3'-UTR,intron-Distal3.821805.45107HepG2FUBP3
chr5171288763171288891-3'-UTR,intron-Distal6.0950113.31323HepG2FUBP3
chr5171289443171289487-3'-UTR,intron-Distal3.613846.30427K562FAM120A
chr5171290104171290170-3'-UTR,intron-Distal3.732683.49438K562DDX6
chr5171337729171337802-3'-UTR,CDS,intron-Distal,intron-Proximal4.042293.56019HepG2GRWD1
chr5171288889171288928-3'-UTR,intron-Distal3.974063.34480K562PUM2
chr5171289101171289150-3'-UTR,intron-Distal4.041055.73324K562FAM120A
chr5171289015171289080-3'-UTR,intron-Distal3.9541611.83218K562FAM120A
chr5171289976171290020-3'-UTR,intron-Distal3.261653.60337HepG2FUBP3
chr5171337725171337789-3'-UTR,CDS,intron-Distal,intron-Proximal3.881553.01428K562UCHL5
chr5171288982171289091-3'-UTR,intron-Distal5.7324824.97259K562UPF1
chr5171289276171289332-3'-UTR,intron-Distal4.5539113.10292K562UPF1
chr5171305055171305134-3'-UTR,CDS,intron-Distal,intron-Proximal4.461593.89826HepG2BCLAF1
chr5171305059171305107-3'-UTR,CDS,intron-Distal3.869373.67607K562YBX3
chr5171289873171289933-3'-UTR,intron-Distal3.995097.87287K562FAM120A
chr5171289786171289827-3'-UTR,intron-Distal3.147403.77257K562FAM120A
chr5171433507171433601-5'-UTR,intron-Distal,intron-Proximal4.738655.07098K562DDX3X
chr5171423911171424037-5'-UTR,CDS,intron-Distal,intron-Proximal3.530315.11891HepG2GRWD1
chr5171433483171433640-5'-UTR,CDS,intron-Distal,intron-Proximal3.8327519.11348HepG2DDX3X
chr5171433386171433492-CDS,intron-Distal3.9693811.41099HepG2PRPF8
chr5171433450171433507-CDS,intron-Distal3.694923.86664K562DDX3X
chr5171384718171384872-intron-Distal,intron-Proximal4.3574611.03709HepG2QKI
chr5171358364171358459-intron-Distal4.184903.27946HepG2HNRNPM
chr5171419410171419489-intron-Distal3.870513.47525K562MATR3
chr5171432992171433046-intron-Distal4.753034.38829HepG2NKRF
chr5171431706171431804-intron-Distal3.812615.51953HepG2SFPQ
chr5171419401171419510-intron-Distal4.8329132.87341HepG2PTBP1
chr5171336692171336800-intron-Distal4.156773.45317HepG2HNRNPL
chr5171371017171371206-intron-Distal3.455464.52210K562KHSRP
chr5171401610171401688-intron-Distal3.606413.76025HepG2ILF3
chr5171402378171402433-intron-Distal5.023025.31214HepG2XPO5
chr5171376104171376177-intron-Distal4.101554.10688K562KHSRP
chr5171417056171417140-intron-Distal4.589246.11515K562PTBP1
chr5171432017171432078-intron-Distal4.491924.66266K562TARDBP
chr5171369745171369809-intron-Distal4.225504.33299K562ILF3
chr5171416856171416987-intron-Distal3.051306.53997HepG2HNRNPL
chr5171431838171431890-intron-Distal4.098413.34609K562TARDBP
chr5171429717171429774-intron-Distal4.274275.53837HepG2XPO5
chr5171428916171428996-intron-Distal3.308124.12870K562PTBP1
chr5171427482171427546-intron-Distal3.002324.10915HepG2QKI
chr5171417043171417164-intron-Distal5.7051424.40160HepG2PCBP2
chr5171417055171417158-intron-Distal6.0326115.77934HepG2PTBP1
chr5171299312171299428-intron-Distal3.996283.30440HepG2QKI
chr5171402997171403113-intron-Distal3.875487.33240HepG2PCBP2
chr5171368934171369079-intron-Distal3.466656.07250K562HLTF
chr5171295375171295445-intron-Distal4.704314.22343HepG2XPO5
chr5171412898171412955-intron-Distal3.031215.17888HepG2HNRNPC
chr5171368229171368328-intron-Distal3.769454.01468K562HLTF
chr5171405701171405752-intron-Distal5.106378.60156HepG2HNRNPM
chr5171340764171340854-intron-Distal5.301965.14653K562EIF4G2
chr5171394370171394529-intron-Distal3.284944.10408K562KHSRP
chr5171409136171409228-intron-Distal3.653463.22908HepG2CSTF2
chr5171429129171429237-intron-Distal3.274004.71462HepG2HNRNPL
chr5171428298171428389-intron-Distal5.506829.03229HepG2QKI
chr5171312094171312187-intron-Distal3.986273.26547HepG2HLTF
chr5171342615171342691-intron-Distal3.196753.15317HepG2HNRNPL
chr5171405752171405809-intron-Distal3.659234.14896HepG2HNRNPM
chr5171369742171369809-intron-Distal3.642205.84478HepG2DDX59
chr5171408782171408890-intron-Distal3.874363.45805K562KHSRP
chr5171401632171401746-intron-Distal4.390584.58544K562ILF3
chr5171419387171419479-intron-Distal5.6490325.17316K562PTBP1
chr5171427582171427671-intron-Distal3.617637.49954HepG2QKI
chr5171433389171433431-intron-Distal3.978458.38575HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXW11 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXW11 is not available on ENCORE database.

  • 58 RBPs can affect the levels of FBXW11.  








The Knockdown/knockout RNA-Seq assay for FBXW11 is not available on ENCORE database.





58 RBPs can affect the gene expression of FBXW11 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXW11ENSG00000072803.13726.404801301.00700-0.840806.550804.01160HepG2AARS
FBXW11ENSG00000072803.13856.107501327.36940-0.632704.776703.54480HepG2BCCIP
FBXW11ENSG00000072803.13656.945301363.63560-1.0536020.8250018.16780HepG2CPSF7
FBXW11ENSG00000072803.131498.868801828.75110-0.287004.470403.56460HepG2DAZAP1
FBXW11ENSG00000072803.131050.489601333.24250-0.343903.541502.23210HepG2DDX1
FBXW11ENSG00000072803.13708.476301221.20940-0.785505.762203.98230HepG2DDX27
FBXW11ENSG00000072803.131097.601001295.69670-0.239402.694702.04980HepG2DNAJC2
FBXW11ENSG00000072803.13796.126801196.72090-0.588004.799703.61540HepG2EEF2
FBXW11ENSG00000072803.131167.062901837.59620-0.654907.185706.26300HepG2EIF2S1
FBXW11ENSG00000072803.13899.385002030.81700-1.1750018.3847016.75110HepG2EIF4A3
FBXW11ENSG00000072803.132067.851802562.90660-0.309604.414403.68640HepG2ETF1
FBXW11ENSG00000072803.131024.427601672.17990-0.706907.473506.27210HepG2FIP1L1
FBXW11ENSG00000072803.131008.679201554.51590-0.624005.862504.95500HepG2GPKOW
FBXW11ENSG00000072803.13916.944601319.86500-0.525505.711504.82760HepG2HNRNPA1
FBXW11ENSG00000072803.131055.558001468.07240-0.475904.795203.90040HepG2HNRNPC
FBXW11ENSG00000072803.131568.579301924.40520-0.295002.138101.51910HepG2HNRNPK
FBXW11ENSG00000072803.131443.768601665.88240-0.206402.324401.69880HepG2HNRNPL
FBXW11ENSG00000072803.13640.961401483.49620-1.2107021.1603019.67570HepG2HNRNPLL
FBXW11ENSG00000072803.131162.361301458.36890-0.327303.051402.41740HepG2HNRNPU
FBXW11ENSG00000072803.131194.618801441.07180-0.270602.403301.72680HepG2IGF2BP1
FBXW11ENSG00000072803.131132.814501489.68120-0.395107.294606.16430HepG2ILF2
FBXW11ENSG00000072803.131039.449701316.66440-0.341104.897503.54650HepG2KIF1C
FBXW11ENSG00000072803.131411.254202049.55060-0.538305.189904.29790HepG2MAGOH
FBXW11ENSG00000072803.131654.400302109.62200-0.350702.411001.81710HepG2NCBP2
FBXW11ENSG00000072803.131449.680401878.86110-0.374102.715101.99960HepG2PABPC4
FBXW11ENSG00000072803.131489.945301834.72620-0.300303.902403.20770HepG2PCBP1
FBXW11ENSG00000072803.13905.321301300.75430-0.522807.655106.47590HepG2PPIL4
FBXW11ENSG00000072803.131285.341501731.00270-0.429504.595403.84990HepG2PUF60
FBXW11ENSG00000072803.132208.257901837.503400.265103.556902.90200HepG2PUM1
FBXW11ENSG00000072803.131225.822701467.04330-0.259203.037802.39980HepG2PUS1
FBXW11ENSG00000072803.132090.998701408.121500.570303.128702.38170HepG2RAVER1
FBXW11ENSG00000072803.131562.454102077.68710-0.411206.696005.91740HepG2NELFE
FBXW11ENSG00000072803.131484.780001935.10370-0.382205.931205.07550HepG2RECQL
FBXW11ENSG00000072803.131367.95810996.177200.457403.646302.76110HepG2RRP9
FBXW11ENSG00000072803.131067.097201298.76160-0.283403.323302.62830HepG2SAFB2
FBXW11ENSG00000072803.131028.628901514.60860-0.5582013.1001011.86220HepG2SMN1
FBXW11ENSG00000072803.131005.812501435.64100-0.513303.378002.30770HepG2SMNDC1
FBXW11ENSG00000072803.133100.540701633.850500.924109.016507.61250HepG2SNRNP70
FBXW11ENSG00000072803.133059.009802419.462000.338306.472605.79420HepG2SRFBP1
FBXW11ENSG00000072803.131574.429102100.68850-0.416007.625106.85510HepG2SSB
FBXW11ENSG00000072803.13531.770101609.29290-1.5976013.5145011.37680HepG2TBRG4
FBXW11ENSG00000072803.13988.195301417.20280-0.520206.991106.26320HepG2TIAL1
FBXW11ENSG00000072803.13813.913701429.73740-0.8128020.5380019.18210HepG2TRIM56
FBXW11ENSG00000072803.131187.265501430.35770-0.268701.860001.33420HepG2U2AF1
FBXW11ENSG00000072803.13572.29890767.54680-0.423502.504501.78260HepG2UCHL5
FBXW11ENSG00000072803.131238.574701534.35940-0.309004.000103.18410HepG2UPF1
FBXW11ENSG00000072803.13699.720601189.91180-0.766005.456204.01650HepG2UPF2
FBXW11ENSG00000072803.131736.836701481.359100.229402.102301.56600HepG2UTP3
FBXW11ENSG00000072803.131104.714901469.26170-0.411402.305701.31320HepG2XPO5
FBXW11ENSG00000072803.13729.678801278.93550-0.809608.667807.40110HepG2XRN2
FBXW11ENSG00000072803.131481.548901687.49740-0.187802.134101.63590HepG2ZNF622
FBXW11ENSG00000072803.13363.41410565.97380-0.639103.404402.07820K562AARS
FBXW11ENSG00000072803.131764.520901126.158700.647807.948207.03950K562AQR
FBXW11ENSG00000072803.13484.80400621.54910-0.358502.991201.60990K562DDX27
FBXW11ENSG00000072803.13884.72880673.111200.394302.336401.39520K562EIF3D
FBXW11ENSG00000072803.13566.65900732.05070-0.369502.540801.75500K562EIF4A3
FBXW11ENSG00000072803.13482.64870866.34260-0.8440010.302708.54410K562FIP1L1
FBXW11ENSG00000072803.13606.09910766.01660-0.337802.210901.49960K562GPKOW
FBXW11ENSG00000072803.13786.865901154.84350-0.553505.766304.67100K562GRSF1
FBXW11ENSG00000072803.13576.20620747.71790-0.375902.529301.69570K562METAP2
FBXW11ENSG00000072803.13757.03290983.47390-0.377502.709301.89890K562PPIG
FBXW11ENSG00000072803.13880.48090611.692100.525404.310203.37460K562PRPF8
FBXW11ENSG00000072803.132064.893101653.076600.320803.454802.25380K562PUM1
FBXW11ENSG00000072803.13721.39850943.68070-0.387502.744901.65800K562NELFE
FBXW11ENSG00000072803.13797.14310623.133600.355202.063701.36300K562RPS19
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXW11 is not available on ENCORE database.





9 RBPs can affect the splicing of FBXW11 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.427000.000670.01508excludedK562SF3B4
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.340000.000760.02517excludedK562AKAP8L
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.316000.000160.00288excludedHepG2U2AF2
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.380000.000000.00001excludedK562PUS1
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.227000.000030.00412excludedHepG2FTO
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.173000.003920.08787excludedHepG2SF3A3
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.413000.000350.00829excludedK562U2AF2
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.322000.000220.00824excludedK562AGGF1
SEFBXW11ENSG00000072803.13chr5-171341346171341409171337575171337801171433461171433877-0.383000.001110.02113excludedK562HNRNPC
A3SSFBXW11ENSG00000072803.13chr5-1712977511712979131712977511712978621712998751712999940.191000.000000.00000longerK562AQR
A3SSFBXW11ENSG00000072803.13chr5-1713269361713271681713269361713271041713375751713378010.057000.000470.00351longerK562AQR
A3SSFBXW11ENSG00000072803.13chr5-1713034051713036181713034051713035381713050141713051330.067000.000070.00061longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXW11 is not avaliable on ENCORE database.