FAM177A1

General Information

Gene Name       : FAM177A1
Gene ID             : ENSG00000151327.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FAM177A1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAM177A1ENSG00000151327.1217.9712.7915.38ENCSR000AEF
HepG2FAM177A1ENSG00000151327.1272.5776.9474.75ENCSR985KAT
K562FAM177A1ENSG00000151327.1223.5820.5622.07ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FAM177A1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM177A1 RNA is bound by 15 proteins.  







eCLIP assay for FAM177A1 is not avaliable on ENCORE database.





15 proteins are bound to FAM177A1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr143554819835548231+3'-UTR,CDS,intron-Proximal4.767365.91688K562TRA2A
chr143554635535546424+3'-UTR,CDS,intron-Proximal3.281397.66871HepG2BCLAF1
chr143552258935522658+3'-UTR,5'-UTR,CDS,intron-Proximal4.750214.14433K562ZNF800
chr143555226335552339+3'-UTR,intron-Distal3.335085.40232HepG2U2AF2
chr143552257335522631+3'-UTR,5'-UTR,CDS3.457336.39282HepG2GRWD1
chr143554635535546402+3'-UTR,CDS,intron-Proximal3.613885.03335K562UCHL5
chr143554816235548231+3'-UTR,CDS,intron-Proximal4.053223.53067K562SRSF1
chr143554637835546425+3'-UTR,CDS,intron-Proximal4.542295.11007HepG2GRWD1
chr143552261335522666+3'-UTR,5'-UTR,CDS,intron-Proximal3.289953.10237K562AGGF1
chr143552259335522657+3'-UTR,5'-UTR,CDS3.220365.75243K562ZNF622
chr143552260735522660+3'-UTR,5'-UTR,CDS,intron-Proximal4.859829.30195HepG2BCLAF1
chr143552250135522607+3'-UTR,5'-UTR,CDS4.0835512.93761HepG2BCLAF1
chr143554813135548164+3'-UTR,CDS,intron-Proximal3.946213.60441HepG2GRWD1
chr143552248835522662+3'-UTR,5'-UTR,CDS,intron-Proximal3.8199511.85263K562UCHL5
chr143554819535548231+3'-UTR,CDS,intron-Proximal3.111973.66602K562GRWD1
chr143552263135522664+3'-UTR,5'-UTR,CDS,intron-Proximal4.605634.91614HepG2GRWD1
chr143552258835522663+3'-UTR,5'-UTR,CDS,intron-Proximal3.660688.74774HepG2PPIG
chr143554820735548231+3'-UTR,CDS,intron-Proximal4.642744.99268HepG2TRA2A
chr143555036135550446+3'-UTR,5'-UTR,CDS3.9727412.38345HepG2BCLAF1
chr143551570435515789+5'-UTR,CDS,intron-Proximal3.533957.11978K562DDX3X
chr143551562035515668+5'-UTR,intron-Proximal4.049757.94128HepG2DDX3X
chr143551571035515835+5'-UTR,CDS,intron-Proximal3.021035.01560K562UCHL5
chr143551570135515790+5'-UTR,CDS,intron-Proximal3.092274.74301HepG2DDX3X
chr143555022635550255+CDS,intron-Proximal3.180193.92909K562GRWD1
chr143555028435550420+CDS3.028174.41403K562GRWD1
chr143555028635550361+CDS3.7013112.55157HepG2BCLAF1
chr143555022435550273+CDS,intron-Proximal4.126107.48753K562ZNF622
chr143555022735550274+CDS,intron-Proximal4.898886.18872K562TRA2A
chr143555022735550295+CDS,intron-Proximal3.159934.93055K562ZNF800
chr143555022735550396+CDS,intron-Proximal3.278027.63975K562PUM1
chr143551582435515875+CDS,intron-Proximal3.512475.34140HepG2PRPF8
chr143555028335550403+CDS3.477367.28455K562ZNF622
chr143555023035550274+CDS4.023405.94293HepG2BCLAF1
chr143555022335550275+CDS,intron-Proximal4.280814.62931K562SRSF1
chr143555022435550292+CDS,intron-Proximal5.142747.85045HepG2TRA2A
chr143551549435515564+intron-Distal6.4175111.20892HepG2DDX3X
chr143551948535519525+intron-Distal4.229097.04643K562PUM2
chr143555261835552696+intron-Distal4.651574.64001HepG2U2AF2
chr143551937935519451+intron-Distal4.2313514.66762K562PUM2
chr143554582835545951+intron-Distal4.063293.88679HepG2CSTF2
chr143551952535519572+intron-Distal5.4070221.63333K562PUM2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM177A1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM177A1 is not available on ENCORE database.

  • 76 RBPs can affect the levels of FAM177A1.  








The Knockdown/knockout RNA-Seq assay for FAM177A1 is not available on ENCORE database.





76 RBPs can affect the gene expression of FAM177A1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM177A1ENSG00000151327.81270.73620888.931700.515409.042808.07250HepG2ACO1
FAM177A1ENSG00000151327.8513.72830700.49240-0.447403.060702.01570HepG2ADAR
FAM177A1ENSG00000151327.81149.32790893.114200.363804.259503.32330HepG2AKAP8L
FAM177A1ENSG00000151327.81004.303801259.60310-0.326802.374901.81540HepG2BOP1
FAM177A1ENSG00000151327.8771.480801057.31370-0.454702.139601.47370HepG2CNOT7
FAM177A1ENSG00000151327.81796.839301183.714400.6020011.6554010.51140HepG2CELF1
FAM177A1ENSG00000151327.81012.66740745.348400.442103.657302.88580HepG2DDX21
FAM177A1ENSG00000151327.82411.212201382.558100.8023010.749109.59280HepG2DDX3X
FAM177A1ENSG00000151327.8938.07540686.015000.451402.592901.52580HepG2AGO1
FAM177A1ENSG00000151327.8493.852201141.70960-1.2090018.0195016.59640HepG2EIF2S1
FAM177A1ENSG00000151327.8612.007501261.67260-1.0437013.2670011.88830HepG2EIF4A3
FAM177A1ENSG00000151327.81902.704701228.512200.631004.821503.92800HepG2EIF4B
FAM177A1ENSG00000151327.81507.042401255.691200.263102.512201.70650HepG2EIF4G1
FAM177A1ENSG00000151327.8593.70480868.65160-0.549005.470404.29420HepG2EWSR1
FAM177A1ENSG00000151327.81767.919301023.624600.788308.511307.24590HepG2FIP1L1
FAM177A1ENSG00000151327.8602.57450929.41880-0.625204.098602.74900HepG2FUS
FAM177A1ENSG00000151327.81303.77440890.774300.549502.773301.40670HepG2HLTF
FAM177A1ENSG00000151327.8543.01030712.12960-0.391202.625401.99390HepG2HNRNPA1
FAM177A1ENSG00000151327.81545.768101169.766600.402005.582204.33490HepG2HNRNPA2B1
FAM177A1ENSG00000151327.8545.36910792.10470-0.538504.498503.62840HepG2HNRNPC
FAM177A1ENSG00000151327.8822.620201020.45150-0.310902.885802.15530HepG2HNRNPF
FAM177A1ENSG00000151327.8618.11760786.86840-0.348203.385102.72040HepG2HNRNPU
FAM177A1ENSG00000151327.81578.432601092.274700.531104.063202.55960HepG2HSPD1
FAM177A1ENSG00000151327.8934.792401200.36330-0.360802.420801.78410HepG2IGF2BP2
FAM177A1ENSG00000151327.81073.13190828.491900.373203.097902.24380HepG2MSI2
FAM177A1ENSG00000151327.8932.393401275.81430-0.452402.536401.61220HepG2MTPAP
FAM177A1ENSG00000151327.81726.587001310.823300.397302.879102.23400HepG2NCBP2
FAM177A1ENSG00000151327.81340.16850966.331300.471702.176701.40370HepG2PABPC1
FAM177A1ENSG00000151327.81611.307601167.280400.465003.779202.94520HepG2PABPC4
FAM177A1ENSG00000151327.8826.061201135.98060-0.459606.152405.30230HepG2PCBP1
FAM177A1ENSG00000151327.8499.55830701.82510-0.490504.937803.98240HepG2PPIL4
FAM177A1ENSG00000151327.8969.11920667.595500.537604.339003.35140HepG2PRPF8
FAM177A1ENSG00000151327.81321.954101155.947600.193501.770801.31330HepG2PTBP1
FAM177A1ENSG00000151327.81591.773401204.834400.401703.783203.09840HepG2PUF60
FAM177A1ENSG00000151327.81122.634401278.95360-0.188102.050801.52510HepG2PUM1
FAM177A1ENSG00000151327.81643.41920849.064100.952707.229006.11910HepG2RAVER1
FAM177A1ENSG00000151327.81567.139601312.919700.255302.399801.90760HepG2RBM22
FAM177A1ENSG00000151327.81092.73350850.495200.361502.743201.67400HepG2RPS5
FAM177A1ENSG00000151327.8961.63160660.394500.542104.016303.09020HepG2RRP9
FAM177A1ENSG00000151327.81513.265501238.238000.289302.007201.40130HepG2SF3B1
FAM177A1ENSG00000151327.81146.73410865.696200.405502.191901.34970HepG2SMNDC1
FAM177A1ENSG00000151327.82271.107401377.754000.721002.295801.58600HepG2SNRNP70
FAM177A1ENSG00000151327.82234.705601482.913200.5916015.6205014.68470HepG2SRFBP1
FAM177A1ENSG00000151327.81956.018301256.132500.6388015.5748014.64790HepG2SRSF1
FAM177A1ENSG00000151327.81490.469801189.561000.325203.837803.12170HepG2SRSF5
FAM177A1ENSG00000151327.81059.765801287.55250-0.280902.725302.21530HepG2SSB
FAM177A1ENSG00000151327.81263.05500793.469300.670604.624203.05610HepG2SUB1
FAM177A1ENSG00000151327.81631.460401352.890700.270003.361702.68920HepG2SUCLG1
FAM177A1ENSG00000151327.81487.399501101.723700.432902.700701.39320HepG2SUGP2
FAM177A1ENSG00000151327.81281.19680861.459700.572504.715203.86830HepG2SUPV3L1
FAM177A1ENSG00000151327.8936.944801129.15210-0.269202.132501.62850HepG2TAF15
FAM177A1ENSG00000151327.81188.61090875.665500.440703.338102.65400HepG2U2AF1
FAM177A1ENSG00000151327.8700.60860508.899600.461103.194402.38020HepG2UCHL5
FAM177A1ENSG00000151327.81142.60350943.647000.275902.951402.23400HepG2UPF1
FAM177A1ENSG00000151327.8552.61380911.05530-0.7213011.5548010.46380HepG2UTP3
FAM177A1ENSG00000151327.8559.49430848.01220-0.600004.636103.70650HepG2XRN2
FAM177A1ENSG00000151327.8800.20070639.618100.323103.106002.40180HepG2ZC3H8
FAM177A1ENSG00000151327.8721.72110551.329200.388403.559902.93000K562AGGF1
FAM177A1ENSG00000151327.8786.65570605.839900.376702.760501.77980K562AKAP8
FAM177A1ENSG00000151327.8981.66980573.686100.774909.989608.64800K562AKAP8L
FAM177A1ENSG00000151327.8891.12230601.940600.565907.137105.57810K562ATP5C1
FAM177A1ENSG00000151327.8424.28010269.024800.657204.146303.07370K562BOP1
FAM177A1ENSG00000151327.81106.89970841.550100.395303.072002.04560K562CELF1
FAM177A1ENSG00000151327.8529.49220413.048800.358202.294601.34970K562DDX3X
FAM177A1ENSG00000151327.8829.44180617.308000.426104.383203.24430K562DKC1
FAM177A1ENSG00000151327.8278.86530431.54910-0.630004.541103.48940K562EIF4A3
FAM177A1ENSG00000151327.8343.33710246.682300.476902.232701.41620K562FTO
FAM177A1ENSG00000151327.8585.83600435.265300.428502.070101.47090K562G3BP2
FAM177A1ENSG00000151327.8418.47340273.117200.615504.036903.08230K562GPKOW
FAM177A1ENSG00000151327.8884.20450608.813500.538305.332204.10840K562KIF1C
FAM177A1ENSG00000151327.8384.34130233.196900.720703.823302.71360K562KRR1
FAM177A1ENSG00000151327.8363.64210499.38330-0.457602.616601.79930K562MAGOH
FAM177A1ENSG00000151327.8810.54670582.793100.475803.687302.38470K562MAK16
FAM177A1ENSG00000151327.8856.56610682.026400.328602.319201.49880K562MBNL1
FAM177A1ENSG00000151327.8362.90730266.591100.444902.365801.55870K562METAP2
FAM177A1ENSG00000151327.8690.87030478.052100.531102.674101.80920K562NAA15
FAM177A1ENSG00000151327.81257.55290568.917201.1442019.3751017.96850K562PUS1
FAM177A1ENSG00000151327.8912.01150554.342300.7182010.338909.21710K562RBM15
FAM177A1ENSG00000151327.8341.41990465.37310-0.446802.098501.37090K562RBM22
FAM177A1ENSG00000151327.8255.02220403.61740-0.662403.650402.48140K562RPS3
FAM177A1ENSG00000151327.8285.48390389.65280-0.448802.338101.38300K562SRSF4
FAM177A1ENSG00000151327.8575.97740374.747500.620004.332602.70230K562STAU1
FAM177A1ENSG00000151327.8578.46450467.979300.305702.290501.63320K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM177A1 is not available on ENCORE database.





11 RBPs can affect the splicing of FAM177A1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAM177A1ENSG00000151327.8chr14+355463553554642235522483355226573554813235548230-0.058000.000050.00168excludedHepG2U2AF1
SEFAM177A1ENSG00000151327.8chr14+3554635535546422355224053552265735548132355482300.109000.000000.00001includedK562DROSHA
SEFAM177A1ENSG00000151327.8chr14+3554635535546422355224053552265735548132355482300.079000.000020.00424includedK562HNRNPUL1
SEFAM177A1ENSG00000151327.8chr14+355463553554642235522405355226573554813235548230-0.055000.000960.02647excludedK562RBM15
SEFAM177A1ENSG00000151327.8chr14+3554635535546422355224053552265735548132355482300.055000.000000.00479includedHepG2DROSHA
MXEFAM177A1ENSG00000151327.8chr14+3552248335522657355463553554642235515710355158343554813235548230-0.125000.000040.010222includedK562LARP4
MXEFAM177A1ENSG00000151327.8chr14+3552248335522657355463553554642235515710355158343554813235548230-0.120000.002290.038472includedK562PUS1
MXEFAM177A1ENSG00000151327.8chr14+3552248335522657355463553554642235515710355158343554813235548230-0.160000.002610.077042includedHepG2TAF15
MXEFAM177A1ENSG00000151327.8chr14+35522483355226573554635535546422355157103551583435548132355482300.205000.000180.017871includedHepG2NOLC1
MXEFAM177A1ENSG00000151327.8chr14+3552248335522657355463553554642235515710355158343554813235548230-0.123000.005810.091462includedHepG2DDX55
MXEFAM177A1ENSG00000151327.8chr14+3552248335522657355463553554642235515710355158343554813235548230-0.189000.000010.003172includedK562PUM1
MXEFAM177A1ENSG00000151327.8chr14+3552248335522657355463553554642235515710355158343554813235548230-0.119000.000310.013962includedK562PPIL4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM177A1 is not avaliable on ENCORE database.