EXOC4

General Information

Gene Name       : EXOC4
Gene ID             : ENSG00000131558.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EXOC4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXOC4ENSG00000131558.1426.3722.8524.61ENCSR000AEF
HepG2EXOC4ENSG00000131558.1417.7518.5218.13ENCSR985KAT
K562EXOC4ENSG00000131558.1432.6531.3131.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXOC4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXOC4 RNA is bound by 34 proteins.  







eCLIP assay for EXOC4 is not avaliable on ENCORE database.





34 proteins are bound to EXOC4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr7133749357133749448+3'-UTR,intron-Distal,intron-Proximal3.249215.88228K562TIA1
chr7133749349133749386+3'-UTR,intron-Proximal3.711204.06768K562NOLC1
chr7133749790133749830+3'-UTR,intron-Distal5.8971525.51613K562PABPC4
chr7133750005133750066+3'-UTR,intron-Distal4.427105.37961K562YBX3
chr7133749362133749445+3'-UTR,intron-Distal,intron-Proximal3.312615.60526K562LIN28B
chr7133749350133749447+3'-UTR,intron-Distal,intron-Proximal6.7134118.80239HepG2SUB1
chr7132973675132973698+5'-UTR,CDS,intron-Proximal3.933175.01703K562PUM1
chr7132973695132973779+5'-UTR,CDS3.151914.84290HepG2HLTF
chr7132973674132973861+5'-UTR,CDS,intron-Proximal4.0983133.96389K562ZNF622
chr7132937850132937944+5'-UTR,CDS,intron-Proximal3.2615415.13612K562ZNF622
chr7132959735132959771+5'-UTR,CDS,intron-Proximal3.289119.23212K562ZNF622
chr7132959736132959869+5'-UTR,CDS,intron-Proximal3.682133.37921HepG2UCHL5
chr7132973682132973856+5'-UTR,CDS4.089065.04760HepG2UCHL5
chr7132973690132973732+5'-UTR,CDS3.578283.95068K562DDX24
chr7132973683132973853+5'-UTR,CDS5.8949914.54788HepG2GRWD1
chr7132973680132973746+5'-UTR,CDS3.100107.17439HepG2BCLAF1
chr7133041117133041248+CDS4.8043114.18756HepG2BCLAF1
chr7132973716132973864+CDS3.652597.33518K562MTPAP
chr7133602356133602398+CDS3.453346.35478K562YBX3
chr7132990630132990703+CDS,intron-Proximal3.422596.20035HepG2BCLAF1
chr7132990759132990812+CDS3.989963.53509HepG2HLTF
chr7133041204133041328+CDS,intron-Proximal3.1546915.35416HepG2PPIG
chr7133160150133160226+CDS4.579724.67744K562BUD13
chr7133059581133059603+CDS,intron-Proximal3.450304.06757K562UCHL5
chr7133314806133314861+CDS4.930565.68196HepG2BCLAF1
chr7133041313133041328+CDS,intron-Proximal5.470139.46752K562ZNF622
chr7133041175133041313+CDS4.4857738.36588K562ZNF622
chr7133002112133002147+CDS,intron-Proximal3.578285.77496K562DDX24
chr7132990629132990713+CDS,intron-Proximal3.532833.34034HepG2HLTF
chr7132973779132973872+CDS,intron-Proximal5.015277.68679HepG2HLTF
chr7133041233133041331+CDS,intron-Proximal3.2145511.07159K562UCHL5
chr7132990634132990731+CDS3.321407.93618K562UCHL5
chr7133164803133164867+CDS,intron-Proximal3.259577.36517K562DDX24
chr7133002064133002112+CDS3.147033.79703K562DDX24
chr7133059581133059611+CDS,intron-Proximal3.165283.40321HepG2GRWD1
chr7133580356133580385+CDS3.498273.36945K562ZNF622
chr7132990714132990803+CDS3.550735.58683HepG2GRWD1
chr7132973746132973854+CDS4.3325315.11988HepG2BCLAF1
chr7132990629132990694+CDS,intron-Proximal3.955734.70460K562DDX24
chr7132973818132973871+CDS,intron-Proximal3.815254.14015K562DDX24
chr7132990637132990705+CDS4.481324.14322HepG2FXR2
chr7133041108133041173+CDS3.259577.36517K562DDX24
chr7133041124133041324+CDS4.429805.37883HepG2UCHL5
chr7133164856133164900+CDS,intron-Proximal4.498593.89826HepG2BCLAF1
chr7133059581133059605+CDS,intron-Proximal3.384413.64266HepG2PPIG
chr7133041246133041330+CDS,intron-Proximal3.179108.83088K562DDX24
chr7133314806133314908+CDS,intron-Proximal4.614896.26332HepG2GRWD1
chr7133164801133164896+CDS,intron-Proximal3.024636.05740HepG2GRWD1
chr7133160122133160229+CDS,intron-Proximal3.337459.29110K562DDX24
chr7133041083133041108+CDS,intron-Proximal3.900216.82493K562DDX24
chr7133502128133502226+CDS3.032893.04831K562RBM15
chr7133059598133059681+CDS5.0063511.37040K562DDX24
chr7133041220133041328+CDS,intron-Proximal3.125626.18987HepG2GRWD1
chr7133059580133059604+CDS,intron-Proximal4.616799.61116K562ZNF622
chr7133502140133502276+CDS3.601345.52031HepG2GRWD1
chr7133059595133059700+CDS3.7886613.02953HepG2BCLAF1
chr7132990629132990718+CDS,intron-Proximal3.3131218.37057K562ZNF622
chr7133059581133059598+CDS,intron-Proximal4.468965.23082K562DDX24
chr7133622761133622822+CDS3.308826.40723K562YBX3
chr7133502239133502296+CDS3.819465.10442K562YBX3
chr7132973732132973815+CDS3.244576.67395K562DDX24
chr7133689740133689823+CDS3.725725.95764K562YBX3
chr7133059604133059668+CDS3.7131115.84930K562ZNF622
chr7133059603133059708+CDS3.188147.63960K562UCHL5
chr7133174726133174797+intron-Distal4.241413.60944K562TARDBP
chr7133327124133327200+intron-Distal3.868965.61842HepG2MATR3
chr7133342537133342641+intron-Distal4.423814.10387HepG2SFPQ
chr7133174797133174869+intron-Distal5.000808.86284K562TARDBP
chr7133232513133232603+intron-Distal4.577196.05753HepG2SUGP2
chr7133198712133198854+intron-Distal3.875226.48117K562KHSRP
chr7133382761133382831+intron-Distal3.977584.10688K562KHSRP
chr7133226932133226983+intron-Distal4.157634.39969K562TARDBP
chr7133411461133411528+intron-Distal4.946446.17200HepG2PCBP2
chr7133651664133651723+intron-Distal4.196273.30687K562EXOSC5
chr7133349109133349247+intron-Distal3.379234.17049K562TARDBP
chr7133359294133359417+intron-Distal3.131303.68839K562KHSRP
chr7133355065133355194+intron-Distal4.759114.84226K562NONO
chr7133284190133284243+intron-Distal3.504283.76275K562PTBP1
chr7133694268133694349+intron-Distal3.889613.22972K562TARDBP
chr7133061060133061119+intron-Distal4.2235110.06297K562KHSRP
chr7133164951133165011+intron-Distal,intron-Proximal4.162303.19904K562TIA1
chr7133060925133061027+intron-Distal3.305264.35650K562KHSRP
chr7133242981133243060+intron-Distal4.401094.40847HepG2PTBP1
chr7133405044133405131+intron-Distal3.691753.39089K562KHDRBS1
chr7133327124133327193+intron-Distal3.497564.72029K562MATR3
chr7133241968133242037+intron-Distal4.047466.96393HepG2PCBP2
chr7133198529133198598+intron-Distal3.918093.49011K562KHSRP
chr7133327135133327190+intron-Distal3.296253.69184HepG2SUGP2
chr7133327455133327499+intron-Distal4.029083.04224HepG2SUGP2
chr7133387084133387154+intron-Distal6.4178014.12285HepG2DDX59
chr7133088654133088755+intron-Distal4.434624.80665HepG2QKI
chr7133117253133117343+intron-Distal3.874363.49011K562KHSRP
chr7133351743133351804+intron-Distal3.449203.59803HepG2PTBP1
chr7133361707133361792+intron-Distal4.691196.49093K562TARDBP
chr7133198453133198529+intron-Distal3.111603.90146K562KHSRP
chr7133238210133238269+intron-Distal3.582343.27944K562PTBP1
chr7133626594133626651+intron-Distal4.317083.91475K562PTBP1
chr7133404673133404741+intron-Distal4.674616.49093K562TARDBP
chr7133324043133324160+intron-Distal4.197404.07352K562KHSRP
chr7133520656133520763+intron-Distal4.092613.30440HepG2QKI
chr7133209875133209976+intron-Distal4.681624.78076K562HNRNPM
chr7133358142133358231+intron-Distal4.076483.27829HepG2MATR3
chr7133634060133634142+intron-Distal4.278594.55788HepG2QKI
chr7133024659133024701+intron-Distal3.846053.01445K562EXOSC5
chr7133550839133550919+intron-Distal4.955776.23638HepG2QKI
chr7133242977133243054+intron-Distal5.148566.19339K562PTBP1
chr7133650595133650646+intron-Distal4.164773.59917K562EXOSC5
chr7133528321133528373+intron-Distal4.385064.48623K562EXOSC5
chr7132960849132960953+intron-Distal4.100603.76275K562PTBP1
chr7133421779133421836+intron-Distal3.352543.64762HepG2QKI
chr7133420897133420963+intron-Distal3.885093.30440HepG2QKI
chr7133387082133387175+intron-Distal4.641366.28479HepG2ILF3
chr7133328371133328432+intron-Distal3.301643.51804HepG2HNRNPL
chr7133258362133258455+intron-Distal3.211803.52456K562PTBP1
chr7133387081133387140+intron-Distal6.1419211.47623HepG2PCBP2
chr7133170048133170125+intron-Distal5.261576.95895K562PTBP1
chr7133205504133205593+intron-Distal4.7266715.10611K562PTBP1
chr7133528579133528638+intron-Distal4.338503.89085K562EXOSC5
chr7133244493133244568+intron-Distal5.024606.19339K562PTBP1
chr7133209871133209953+intron-Distal3.889895.28337HepG2HNRNPM
chr7133446504133446643+intron-Distal4.207583.16986HepG2QKI
chr7133219370133219444+intron-Distal3.936033.80954K562HNRNPL
chr7133723322133723371+intron-Distal3.926323.50357HepG2QKI
chr7133091475133091646+intron-Distal4.308124.79477K562KHSRP
chr7133219033133219110+intron-Distal3.381264.13575K562KHSRP
chr7133238293133238352+intron-Distal3.909343.09122HepG2PTBP1
chr7133689843133689962+intron-Distal,intron-Proximal3.560863.94787K562AQR
chr7133387085133387167+intron-Distal3.6751510.57435K562ILF3
chr7133421836133421918+intron-Distal4.546055.20135HepG2QKI
chr7133550772133550839+intron-Distal4.636345.20135HepG2QKI
chr7133169876133169984+intron-Distal3.497475.04973K562KHDRBS1
chr7133696138133696241+intron-Distal4.833594.30178K562PTBP1
chr7133065698133065788+intron-Distal3.550835.02233K562PTBP1
chr7133404606133404715+intron-Distal3.189524.43000HepG2QKI
chr7133205483133205594+intron-Distal4.7532310.21863HepG2PTBP1
chr7133371770133371836+intron-Distal4.262203.46495K562TARDBP
chr7133652046133652100+intron-Distal4.346053.01445K562EXOSC5
chr7133446758133446856+intron-Distal3.667993.24603K562KHSRP
chr7133166019133166104+intron-Distal4.587286.77804HepG2QKI
chr7133351742133351813+intron-Distal3.393084.75362K562PTBP1
chr7133204870133204963+intron-Distal4.039924.43126K562KHDRBS1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXOC4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXOC4 is not available on ENCORE database.

  • 83 RBPs can affect the levels of EXOC4.  








The Knockdown/knockout RNA-Seq assay for EXOC4 is not available on ENCORE database.





83 RBPs can affect the gene expression of EXOC4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXOC4ENSG00000131558.101185.65090943.990800.328702.414701.40930HepG2AATF
EXOC4ENSG00000131558.10571.36620784.14570-0.456702.526601.66660HepG2BCLAF1
EXOC4ENSG00000131558.10897.521301073.77600-0.258702.681902.02450HepG2CKAP4
EXOC4ENSG00000131558.101219.49640884.098100.463902.295801.60270HepG2CNOT7
EXOC4ENSG00000131558.10555.43880793.84400-0.515203.835303.03810HepG2CPSF6
EXOC4ENSG00000131558.101169.30660993.350400.235202.453401.66360HepG2DDX19B
EXOC4ENSG00000131558.101089.811201852.24130-0.765209.283308.19570HepG2DDX3X
EXOC4ENSG00000131558.101197.214901591.12790-0.410402.759402.14250HepG2DDX6
EXOC4ENSG00000131558.10674.792101027.60430-0.606809.294408.19930HepG2DKC1
EXOC4ENSG00000131558.10766.073701011.08100-0.400305.472004.60030HepG2DNAJC2
EXOC4ENSG00000131558.10962.788601529.57560-0.667807.202606.27920HepG2EIF2S1
EXOC4ENSG00000131558.10989.175301690.35400-0.773008.276307.17540HepG2EIF4A3
EXOC4ENSG00000131558.101092.868701645.81000-0.590704.183303.34670HepG2EIF4B
EXOC4ENSG00000131558.101226.967901453.48460-0.244402.449701.65440HepG2EIF4G1
EXOC4ENSG00000131558.101140.850101770.85830-0.6343013.5803012.41340HepG2ETF1
EXOC4ENSG00000131558.101322.534701705.51720-0.366902.652801.97500HepG2FXR1
EXOC4ENSG00000131558.101240.337701582.10630-0.351102.280601.67300HepG2G3BP1
EXOC4ENSG00000131558.10752.081701145.49480-0.607006.524105.49640HepG2HNRNPC
EXOC4ENSG00000131558.101297.011801602.05160-0.304702.158001.53610HepG2HNRNPK
EXOC4ENSG00000131558.101055.107401342.02470-0.347005.028804.14170HepG2HNRNPL
EXOC4ENSG00000131558.10944.188601269.46660-0.427102.603401.41470HepG2HSPD1
EXOC4ENSG00000131558.101095.296801608.17260-0.554105.330404.42030HepG2IGF2BP2
EXOC4ENSG00000131558.10547.81440842.49700-0.621004.464402.89750HepG2KHDRBS1
EXOC4ENSG00000131558.101208.143501642.02010-0.442702.847102.00600HepG2LARP4
EXOC4ENSG00000131558.101085.715201706.11270-0.652106.893805.87220HepG2MAGOH
EXOC4ENSG00000131558.101076.029301715.65820-0.673006.607605.66460HepG2MATR3
EXOC4ENSG00000131558.101095.447301756.06880-0.680807.235506.23510HepG2NCBP2
EXOC4ENSG00000131558.10485.72390808.08970-0.734404.156803.05320HepG2PABPC1
EXOC4ENSG00000131558.101074.848601563.88110-0.541004.895803.94630HepG2PABPC4
EXOC4ENSG00000131558.101120.747201643.95150-0.5527010.711409.64270HepG2PCBP1
EXOC4ENSG00000131558.10708.583601014.93140-0.518406.639005.53580HepG2PPIL4
EXOC4ENSG00000131558.101120.708001672.80250-0.5779011.0036010.05310HepG2PTBP1
EXOC4ENSG00000131558.101256.825301480.38410-0.236202.840002.24080HepG2PUM1
EXOC4ENSG00000131558.10909.666901094.03370-0.266202.702402.09130HepG2PUS1
EXOC4ENSG00000131558.10980.782201644.19890-0.7454012.1906010.83690HepG2RBM25
EXOC4ENSG00000131558.10895.037201224.50570-0.452203.659902.51200HepG2RBM27
EXOC4ENSG00000131558.101392.080701861.65160-0.419306.592405.81770HepG2NELFE
EXOC4ENSG00000131558.101220.660801733.90620-0.506409.134908.11410HepG2RECQL
EXOC4ENSG00000131558.10976.617401202.42370-0.300102.325301.69010HepG2RPLP0
EXOC4ENSG00000131558.10795.728701152.36220-0.534203.072602.07830HepG2RPS10
EXOC4ENSG00000131558.10760.100601129.30190-0.571205.583804.47030HepG2RPS2
EXOC4ENSG00000131558.10892.777901152.79030-0.368802.692201.63180HepG2RPS5
EXOC4ENSG00000131558.10846.186501159.69030-0.454702.805602.12740HepG2SF3A3
EXOC4ENSG00000131558.10642.99800850.10370-0.402802.789802.08030HepG2SF3B1
EXOC4ENSG00000131558.101062.061701741.56680-0.7135016.7076015.44120HepG2SF3B4
EXOC4ENSG00000131558.10998.998601181.73350-0.242402.631202.00070HepG2SMN1
EXOC4ENSG00000131558.101960.586801671.670200.229902.127601.67000HepG2SRFBP1
EXOC4ENSG00000131558.10679.75120914.61690-0.428202.409801.48330HepG2SRSF3
EXOC4ENSG00000131558.10903.042601376.92400-0.6086011.140809.99840HepG2SRSF5
EXOC4ENSG00000131558.10706.915101096.59550-0.6334011.123609.89060HepG2SRSF7
EXOC4ENSG00000131558.10917.700201478.91730-0.6884015.9469014.81800HepG2SRSF9
EXOC4ENSG00000131558.10379.37750772.34960-1.0256010.292808.03300HepG2STIP1
EXOC4ENSG00000131558.101309.642301565.93480-0.257903.110302.45830HepG2SUCLG1
EXOC4ENSG00000131558.101317.729601633.98110-0.310303.367002.75790HepG2TAF15
EXOC4ENSG00000131558.10657.15910836.93300-0.348902.164601.51140HepG2TARDBP
EXOC4ENSG00000131558.101089.508501501.36210-0.462605.431404.27200HepG2TIA1
EXOC4ENSG00000131558.10863.044601105.64590-0.357403.319502.78050HepG2TIAL1
EXOC4ENSG00000131558.10885.413901115.59000-0.333403.669903.03960HepG2TRIM56
EXOC4ENSG00000131558.101120.350001362.42840-0.282202.157301.39280HepG2TUFM
EXOC4ENSG00000131558.10357.21610521.78070-0.546603.442802.60030HepG2UCHL5
EXOC4ENSG00000131558.10756.270301057.10300-0.483106.262604.74760HepG2UTP18
EXOC4ENSG00000131558.10565.69670992.94390-0.8117015.2103013.97510HepG2UTP3
EXOC4ENSG00000131558.104855.814503375.969300.5243015.8906014.64620K562AGGF1
EXOC4ENSG00000131558.104482.870203709.867200.273002.593701.64890K562AKAP8
EXOC4ENSG00000131558.104090.850203512.895200.219601.842101.30460K562AKAP8L
EXOC4ENSG00000131558.102021.810402807.88900-0.473803.614302.96110K562AQR
EXOC4ENSG00000131558.104445.683703685.959700.270302.649601.75630K562ATP5C1
EXOC4ENSG00000131558.103239.353104034.31880-0.316602.911201.69700K562CCDC124
EXOC4ENSG00000131558.101149.683001584.25700-0.462604.684003.66650K562CPSF6
EXOC4ENSG00000131558.101855.971202333.07800-0.330102.463901.68960K562EIF4A3
EXOC4ENSG00000131558.101530.342001868.37690-0.287902.551701.34070K562EXOSC5
EXOC4ENSG00000131558.101279.167901611.94400-0.333602.530101.71270K562FMR1
EXOC4ENSG00000131558.101237.030002426.31510-0.9719023.2750021.63920K562FXR1
EXOC4ENSG00000131558.101973.769202466.06800-0.321302.789202.03100K562GRSF1
EXOC4ENSG00000131558.101457.765801767.57850-0.278002.245701.70000K562HNRNPC
EXOC4ENSG00000131558.101857.720002428.65840-0.386604.249102.91140K562HNRNPL
EXOC4ENSG00000131558.101171.313401501.56190-0.358302.328101.47800K562HNRNPM
EXOC4ENSG00000131558.104803.213903727.898300.365503.958602.94920K562KIF1C
EXOC4ENSG00000131558.102119.715502955.76610-0.479706.441205.13160K562MAGOH
EXOC4ENSG00000131558.101713.375002949.79490-0.7838016.3213014.00740K562MATR3
EXOC4ENSG00000131558.101967.215902197.38540-0.159601.977001.33310K562NSUN2
EXOC4ENSG00000131558.103568.103102238.094400.672802.841701.83480K562PABPN1
EXOC4ENSG00000131558.102162.071102629.93000-0.282602.475301.55260K562PCBP2
EXOC4ENSG00000131558.101116.928601523.46260-0.447803.777102.90140K562PRPF8
EXOC4ENSG00000131558.101876.637302871.69960-0.6138010.730109.48300K562PTBP1
EXOC4ENSG00000131558.103103.827703911.18050-0.333602.495401.72180K562PUF60
EXOC4ENSG00000131558.103554.482904160.90290-0.227302.578201.54970K562PUM1
EXOC4ENSG00000131558.105148.217303483.498900.563404.909604.21270K562PUS1
EXOC4ENSG00000131558.104367.020303394.417700.363406.016605.16870K562RBM15
EXOC4ENSG00000131558.101670.714002753.70710-0.7209011.595809.70200K562RBM22
EXOC4ENSG00000131558.103481.245502046.372500.766403.068901.78120K562SF1
EXOC4ENSG00000131558.101070.861601438.51320-0.425803.062602.03870K562SF3B1
EXOC4ENSG00000131558.101902.120602387.47350-0.327903.236902.08180K562SRSF4
EXOC4ENSG00000131558.101436.972801716.76980-0.256702.828201.64510K562SRSF7
EXOC4ENSG00000131558.101398.852601828.40780-0.386304.352903.31640K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXOC4 is not available on ENCORE database.





2 RBPs can affect the splicing of EXOC4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEXOC4ENSG00000131558.10chr7+1329382951329384601329378541329379431329597361329599260.101000.000000.00000includedK562AQR
SEEXOC4ENSG00000131558.10chr7+1329382951329384601329378541329379431329597361329599260.059000.000100.00581includedHepG2HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXOC4 is not avaliable on ENCORE database.