CRK

General Information

Gene Name       : CRK
Gene ID             : ENSG00000167193.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CRK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CRKENSG00000167193.713.7913.5113.65ENCSR000AEF
HepG2CRKENSG00000167193.725.5534.1229.84ENCSR985KAT
K562CRKENSG00000167193.719.1218.3618.74ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CRK is not avaliable on ENCORE database.



Proteins bound to RNA
  • CRK RNA is bound by 27 proteins.  







eCLIP assay for CRK is not avaliable on ENCORE database.





27 proteins are bound to CRK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1713266811326756-3'-UTR,intron-Distal,intron-Proximal3.793823.19904K562TIA1
chr1713240221324077-3'-UTR,intron-Distal3.954965.51967HepG2FUBP3
chr1713263031326386-3'-UTR,CDS,intron-Distal3.212775.39816K562LIN28B
chr1713240841324123-3'-UTR,intron-Distal4.418388.29571K562PUM2
chr1713253621325444-3'-UTR,intron-Distal,intron-Proximal4.7322512.47428K562PABPC4
chr1713239981324136-3'-UTR,intron-Distal3.393864.17167HepG2ZC3H11A
chr1713260671326182-3'-UTR,intron-Distal3.523415.35486K562UPF1
chr1713266331326759-3'-UTR,intron-Distal,intron-Proximal3.360234.53184K562IGF2BP1
chr1713269111326962-3'-UTR,CDS,intron-Distal3.556883.03452HepG2U2AF2
chr1713263561326411-3'-UTR,CDS,intron-Distal5.122038.44976K562PUM2
chr1713240351324076-3'-UTR,intron-Distal3.655355.12038K562PUM2
chr1713262941326365-3'-UTR,CDS,intron-Distal4.130225.19413HepG2LIN28B
chr1713244241324495-3'-UTR,intron-Distal4.257123.89948K562YBX3
chr1713241751324257-3'-UTR,intron-Distal5.025055.29571HepG2FUBP3
chr1713593701359512-5'-UTR,CDS,intron-Distal,intron-Proximal4.1827726.31394HepG2DDX3X
chr1713594241359541-5'-UTR,intron-Distal,intron-Proximal3.271469.69932HepG2NCBP2
chr1713400181340118-CDS,intron-Distal,intron-Proximal3.425836.82513HepG2PRPF8
chr1713400851340248-CDS,intron-Distal,intron-Proximal3.321405.41277K562UCHL5
chr1713401681340251-CDS,intron-Distal,intron-Proximal3.070615.00751HepG2BCLAF1
chr1713593191359372-CDS,intron-Distal3.702994.83336HepG2FAM120A
chr1713398811339940-CDS,intron-Distal,intron-Proximal5.351516.01989HepG2PRPF8
chr1713400581340135-CDS,intron-Distal,intron-Proximal3.042163.73413HepG2PPIG
chr1713401731340304-CDS,intron-Distal,intron-Proximal3.482384.72530HepG2G3BP1
chr1713592861359370-CDS,intron-Distal4.7196811.73310HepG2DDX3X
chr1713537421353807-intron-Distal4.023963.43813HepG2HNRNPC
chr1713328631332927-intron-Distal3.351274.34776K562ILF3
chr1713589411358996-intron-Distal3.738383.52528HepG2FAM120A
chr1713331791333221-intron-Distal4.278274.24441HepG2ILF3
chr1713278941328091-intron-Distal3.949693.77875HepG2ILF3
chr1713396131339693-intron-Distal5.689849.73701HepG2QKI
chr1713590101359087-intron-Distal3.626266.03140HepG2PRPF4
chr1713391441339199-intron-Distal3.451786.10762HepG2PTBP1
chr1713527121352819-intron-Distal3.769613.50045HepG2SFPQ
chr1713527141352829-intron-Distal3.337123.61506K562NONO
chr1713496261349747-intron-Distal3.067194.92335K562NONO
chr1713588811358979-intron-Distal3.267723.65183HepG2XRN2
chr1713580971358223-intron-Distal4.976007.09445K562NONO
chr1713587991358974-intron-Distal3.408213.90917HepG2PRPF4
chr1713590251359084-intron-Distal3.170443.15890HepG2GTF2F1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CRK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CRK is not available on ENCORE database.

  • 67 RBPs can affect the levels of CRK.  








The Knockdown/knockout RNA-Seq assay for CRK is not available on ENCORE database.





67 RBPs can affect the gene expression of CRK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CRKENSG00000167193.71812.425001382.070700.391006.787305.92090HepG2ACO1
CRKENSG00000167193.72587.473201737.025200.574805.223704.52190HepG2AKAP1
CRKENSG00000167193.71642.977001136.824800.531205.955305.11690HepG2BOP1
CRKENSG00000167193.71542.230001161.699900.408704.417503.47050HepG2CALR
CRKENSG00000167193.71870.360001365.474400.453804.038103.11320HepG2CIRBP
CRKENSG00000167193.71635.454801381.834100.243003.071102.37770HepG2CKAP4
CRKENSG00000167193.72585.450501709.880100.5964013.7113012.49380HepG2CELF1
CRKENSG00000167193.71346.753601058.795000.347002.479601.61820HepG2DDX24
CRKENSG00000167193.72303.736101663.921900.469304.153903.40100HepG2DDX3X
CRKENSG00000167193.7620.611301284.22880-1.0491013.0317011.50570HepG2DDX55
CRKENSG00000167193.71555.144701322.283600.233902.345901.71390HepG2DKC1
CRKENSG00000167193.71412.48960826.576500.772909.364007.79740HepG2EIF3D
CRKENSG00000167193.72159.286101518.480000.507804.229603.44370HepG2EIF4A3
CRKENSG00000167193.71965.087801478.489800.410402.364301.72600HepG2EIF4B
CRKENSG00000167193.7947.265201737.53150-0.8752013.8240012.10170HepG2EIF4G2
CRKENSG00000167193.71793.359401350.586600.409004.396203.34800HepG2EWSR1
CRKENSG00000167193.71927.243501532.140400.330902.287701.65600HepG2FXR1
CRKENSG00000167193.71867.137401508.883600.307202.124601.35050HepG2G3BP2
CRKENSG00000167193.71301.761101689.66410-0.376305.143903.93630HepG2HNRNPA2B1
CRKENSG00000167193.71427.739601674.74870-0.230202.961402.26610HepG2HNRNPL
CRKENSG00000167193.7833.122801129.06130-0.438503.301802.62010HepG2HNRNPLL
CRKENSG00000167193.71053.108901311.04370-0.316103.763003.06680HepG2HNRNPU
CRKENSG00000167193.72253.197701755.169600.360302.131301.41010HepG2LARP4
CRKENSG00000167193.72502.532601532.675600.707208.740507.58880HepG2MAGOH
CRKENSG00000167193.72363.220601541.244400.616606.082005.17400HepG2MATR3
CRKENSG00000167193.71313.756501823.07690-0.472706.727705.54450HepG2NOL12
CRKENSG00000167193.71841.206301447.024900.347505.015104.23530HepG2PCBP1
CRKENSG00000167193.7937.273001169.34190-0.319203.122702.34380HepG2PPIL4
CRKENSG00000167193.71358.811601166.347000.220201.977801.31590HepG2PRPF4
CRKENSG00000167193.71781.416801472.413700.274703.270602.68550HepG2PTBP1
CRKENSG00000167193.72258.023401740.291300.375603.886903.19400HepG2PUF60
CRKENSG00000167193.72236.167501847.401600.275404.770604.03590HepG2PUM1
CRKENSG00000167193.72675.713801846.048700.535408.983807.80970HepG2PUM2
CRKENSG00000167193.71706.990601407.738000.278003.625502.94010HepG2PUS1
CRKENSG00000167193.71756.843401220.872600.525002.672701.97860HepG2RAVER1
CRKENSG00000167193.72287.934901638.645300.481409.204208.32010HepG2NELFE
CRKENSG00000167193.72207.838601827.326100.272802.074601.47310HepG2RPLP0
CRKENSG00000167193.72239.357901503.638200.574504.485003.61530HepG2SF3A3
CRKENSG00000167193.71457.349901117.560600.382903.176102.42210HepG2SF3B1
CRKENSG00000167193.73429.000602350.694000.5446016.6105015.65480HepG2SRFBP1
CRKENSG00000167193.72435.315201600.078200.6059015.6365014.70820HepG2SRSF1
CRKENSG00000167193.72218.534101718.290800.368506.011405.14110HepG2SRSF5
CRKENSG00000167193.71658.573201301.756300.349405.173904.46130HepG2SRSF9
CRKENSG00000167193.72339.363002040.993200.196702.296501.81990HepG2SSB
CRKENSG00000167193.72340.983801954.164300.260503.910203.19370HepG2SUCLG1
CRKENSG00000167193.71034.630401438.23670-0.475206.792905.98280HepG2TAF15
CRKENSG00000167193.7462.883301273.83220-1.4605040.0568038.56090HepG2TIAL1
CRKENSG00000167193.71059.303801285.31780-0.279002.982802.40230HepG2TRIM56
CRKENSG00000167193.7893.122501316.57110-0.559905.337004.48060HepG2U2AF1
CRKENSG00000167193.7899.664901333.49850-0.5678010.690409.47960HepG2UPF1
CRKENSG00000167193.71598.419201287.438400.312003.878503.18770HepG2UTP3
CRKENSG00000167193.7966.123501258.47940-0.381402.548501.85150HepG2XRN2
CRKENSG00000167193.71374.315901151.060100.255702.920202.23290HepG2ZC3H8
CRKENSG00000167193.7625.90350799.35960-0.352903.240202.63510K562AGGF1
CRKENSG00000167193.72049.029001467.581400.481404.813004.07740K562AQR
CRKENSG00000167193.71851.436801195.550000.6309014.1105012.75170K562DDX47
CRKENSG00000167193.7319.18050571.55270-0.840505.111302.24600K562DDX55
CRKENSG00000167193.71010.284201209.79030-0.260002.306601.64080K562EIF2S2
CRKENSG00000167193.71307.44960824.769800.664606.171004.54120K562EIF3D
CRKENSG00000167193.7914.11060716.625700.351002.989902.16220K562EIF3G
CRKENSG00000167193.71053.13170659.104300.676007.982106.58660K562EIF4A3
CRKENSG00000167193.7797.568701070.09800-0.424103.497902.53490K562FIP1L1
CRKENSG00000167193.71304.42000685.439900.9282021.0011019.44670K562FXR1
CRKENSG00000167193.71011.61850778.528400.377702.491401.32500K562HNRNPK
CRKENSG00000167193.7393.36750779.14160-0.986009.995007.61190K562IGF2BP2
CRKENSG00000167193.71218.64570819.136300.573005.701804.48350K562MAGOH
CRKENSG00000167193.71022.76900817.518400.323102.514301.63800K562MATR3
CRKENSG00000167193.7750.22750902.25250-0.266202.310801.56980K562MTPAP
CRKENSG00000167193.7399.17460606.57160-0.603704.905603.65670K562PSIP1
CRKENSG00000167193.71056.93980795.820600.409303.909803.13340K562PTBP1
CRKENSG00000167193.72673.940701839.862300.539307.128505.81400K562PUF60
CRKENSG00000167193.72299.173601956.781700.232502.312301.34500K562PUM1
CRKENSG00000167193.7599.47400824.98270-0.460703.776503.15620K562PUS1
CRKENSG00000167193.71018.25370763.537400.415202.761401.94640K562RPS19
CRKENSG00000167193.71199.89490989.165100.278502.514801.73480K562SF3A3
CRKENSG00000167193.71013.21870780.137100.377003.191502.43690K562SRSF1
CRKENSG00000167193.7977.66020750.758600.380903.372602.46750K562SYNCRIP
CRKENSG00000167193.7983.70600789.619500.317002.044501.42990K562TARDBP
CRKENSG00000167193.7334.90310583.41160-0.800806.724705.20970K562TIAL1
CRKENSG00000167193.7473.74210619.88040-0.387902.457701.57550K562TRIM56
CRKENSG00000167193.71175.43920945.819800.313503.649202.68610K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CRK is not available on ENCORE database.





4 RBPs can affect the splicing of CRK :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECRKENSG00000167193.7chr17-1339913133998813239821326944134008313404490.245000.000090.00188includedHepG2U2AF2
SECRKENSG00000167193.7chr17-133991313399881323982132694413400831340449-0.290000.000070.03995excludedHepG2GRSF1
A5SSCRKENSG00000167193.7chr17-1339913134044913400831340449132398213269440.194000.002540.04142longerK562AQR
A5SSCRKENSG00000167193.7chr17-1339913134044913400831340449132398213269440.256000.000100.00597longerHepG2U2AF2
A5SSCRKENSG00000167193.7chr17-1339913134044913400831340449132398213269440.341000.000000.00012longerHepG2HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CRK is not avaliable on ENCORE database.