CLPX

General Information

Gene Name       : CLPX
Gene ID             : ENSG00000166855.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CLPX)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CLPXENSG00000166855.926.5533.1329.84ENCSR000AEF
HepG2CLPXENSG00000166855.925.7131.9428.83ENCSR985KAT
K562CLPXENSG00000166855.939.4642.4540.95ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CLPX is not avaliable on ENCORE database.



Proteins bound to RNA
  • CLPX RNA is bound by 22 proteins.  







eCLIP assay for CLPX is not avaliable on ENCORE database.





22 proteins are bound to CLPX RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr156544090365440942-3'-UTR,intron-Distal4.252894.07810K562UPF1
chr156544726565447306-3'-UTR,CDS,intron-Distal4.593114.78529HepG2BCLAF1
chr156544305665443128-3'-UTR,intron-Distal3.685133.55754HepG2U2AF2
chr156544718565447263-3'-UTR,CDS,intron-Distal3.649094.59151HepG2G3BP1
chr156545014765450201-3'-UTR,CDS,intron-Distal3.266626.20035HepG2BCLAF1
chr156544265965442716-3'-UTR,intron-Distal3.065004.31688HepG2UPF1
chr156544238165442439-3'-UTR,intron-Distal4.130335.81489K562UPF1
chr156544316265443253-3'-UTR,CDS,intron-Distal3.799699.72545K562ZNF622
chr156544219065442200-3'-UTR,intron-Distal3.378664.96603K562UPF1
chr156544154665441595-3'-UTR,intron-Distal3.167933.55461K562UPF1
chr156544716665447267-3'-UTR,CDS,intron-Distal3.002193.04831K562RBM15
chr156545012765450223-3'-UTR,CDS,intron-Distal3.322599.27085K562YBX3
chr156544185265441896-3'-UTR,intron-Distal4.140447.15603K562UPF1
chr156544306665443146-3'-UTR,intron-Distal4.8807149.09243K562PUM2
chr156544070865440785-3'-UTR,intron-Distal3.121374.07923K562UPF1
chr156544252165442573-3'-UTR,intron-Distal4.413923.35877HepG2UPF1
chr156544216065442190-3'-UTR,intron-Distal3.630486.40324K562UPF1
chr156544176465441794-3'-UTR,intron-Distal4.239893.20319K562UPF1
chr156544242965442505-3'-UTR,intron-Distal4.0396912.32151HepG2UPF1
chr156544228965442339-3'-UTR,intron-Distal3.141695.45410K562UPF1
chr156544288565443016-3'-UTR,intron-Distal4.1836024.11281K562PUM2
chr156545007865450147-3'-UTR,CDS,intron-Distal,intron-Proximal3.687843.94979HepG2BCLAF1
chr156547742165477598-5'-UTR,CDS,intron-Distal,intron-Proximal4.282118.83090K562FXR2
chr156547756065477576-5'-UTR,intron-Distal,intron-Proximal3.254365.51805K562YBX3
chr156547759165477658-5'-UTR,intron-Distal,intron-Proximal3.330504.61386K562DROSHA
chr156547759565477678-5'-UTR,intron-Distal,intron-Proximal4.1195812.08978K562GTF2F1
chr156547761365477669-5'-UTR,intron-Distal,intron-Proximal4.082996.74202K562NCBP2
chr156547742965477671-5'-UTR,CDS,intron-Distal,intron-Proximal3.802348.13782HepG2DDX3X
chr156547752565477560-5'-UTR,intron-Distal,intron-Proximal3.661858.84704K562YBX3
chr156547758765477670-5'-UTR,intron-Distal,intron-Proximal3.178785.27768K562DDX6
chr156547757165477677-5'-UTR,intron-Distal,intron-Proximal3.5798011.06072K562FTO
chr156547757265477677-5'-UTR,intron-Distal,intron-Proximal4.9725816.12720HepG2PRPF4
chr156547758665477671-5'-UTR,intron-Distal,intron-Proximal4.129464.16295K562FUS
chr156547751265477668-5'-UTR,intron-Distal,intron-Proximal3.1661815.44276K562DDX3X
chr156547756065477677-5'-UTR,intron-Distal,intron-Proximal3.409289.99409HepG2NCBP2
chr156547129665471364-CDS,intron-Distal4.422597.53358HepG2BCLAF1
chr156545090965450951-CDS,intron-Distal,intron-Proximal4.305356.65960HepG2BCLAF1
chr156547741665477478-CDS,intron-Distal3.284143.04831K562RBM15
chr156545491165454979-CDS,intron-Distal,intron-Proximal4.653908.77485HepG2PRPF8
chr156547129565471366-CDS,intron-Distal3.865923.11282HepG2G3BP1
chr156545645165456512-CDS,intron-Distal3.395026.60490HepG2BCLAF1
chr156544406865444168-intron-Distal4.017773.89294K562KHSRP
chr156545382565453952-intron-Distal3.801435.98773K562KHSRP
chr156547357865473649-intron-Distal4.392643.12827HepG2U2AF2
chr156547113165471267-intron-Distal,intron-Proximal4.754886.94732K562KHSRP
chr156547732165477367-intron-Distal3.006213.01994K562BUD13
chr156544829565448374-intron-Distal4.655485.62258K562KHSRP
chr156547582865475921-intron-Distal4.944536.76922HepG2PTBP1
chr156547583065475927-intron-Distal5.504287.41017K562PTBP1
chr156545287865452975-intron-Distal5.214955.62492K562EIF4G2
chr156547071465470814-intron-Distal3.264035.78064K562KHSRP
chr156547109265471175-intron-Distal,intron-Proximal4.356454.53660HepG2KHSRP
chr156547081465470890-intron-Distal4.222718.64567K562KHSRP
chr156545076765450845-intron-Distal,intron-Proximal4.238343.89565K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CLPX is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CLPX is not available on ENCORE database.

  • 76 RBPs can affect the levels of CLPX.  








The Knockdown/knockout RNA-Seq assay for CLPX is not available on ENCORE database.





76 RBPs can affect the gene expression of CLPX :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CLPXENSG00000166855.51085.194401807.96110-0.736404.717203.42920HepG2CCAR1
CLPXENSG00000166855.51199.968401412.86550-0.235602.692602.03430HepG2CKAP4
CLPXENSG00000166855.5804.500301158.62640-0.526304.736003.85670HepG2CPSF6
CLPXENSG00000166855.52089.061701708.756900.289803.632002.91530HepG2CELF1
CLPXENSG00000166855.51530.614801837.28790-0.263503.539102.71810HepG2DAZAP1
CLPXENSG00000166855.5813.726901077.78300-0.405503.373502.62960HepG2DDX21
CLPXENSG00000166855.5905.224501351.91760-0.5787010.143409.01060HepG2DKC1
CLPXENSG00000166855.5817.048001048.21620-0.359404.686603.87360HepG2DNAJC2
CLPXENSG00000166855.51273.865401726.80310-0.438903.572502.90330HepG2EIF2S1
CLPXENSG00000166855.5976.946401908.37960-0.9660012.6621011.32250HepG2EIF4A3
CLPXENSG00000166855.52048.690502399.81920-0.228202.549201.96840HepG2ETF1
CLPXENSG00000166855.51044.504801477.39660-0.500203.109301.92570HepG2FUS
CLPXENSG00000166855.51319.750901925.29580-0.544805.359104.41670HepG2FXR1
CLPXENSG00000166855.51436.422701786.08840-0.314301.926601.36640HepG2G3BP1
CLPXENSG00000166855.5602.75900810.29320-0.426903.183202.21340HepG2GEMIN5
CLPXENSG00000166855.5635.954901067.69450-0.747509.516108.42400HepG2HNRNPA1
CLPXENSG00000166855.5814.303301187.61000-0.544405.508704.55790HepG2HNRNPC
CLPXENSG00000166855.51306.368201808.35620-0.469104.562603.68490HepG2HNRNPK
CLPXENSG00000166855.5984.474101253.37870-0.348402.374601.78640HepG2HNRNPLL
CLPXENSG00000166855.5840.177601179.75850-0.489707.504006.54350HepG2HNRNPU
CLPXENSG00000166855.51381.736701815.55340-0.393903.087702.37960HepG2IGF2BP2
CLPXENSG00000166855.5933.618501205.08470-0.368205.578904.56910HepG2ILF2
CLPXENSG00000166855.51432.983201925.96710-0.426603.390302.66360HepG2MAGOH
CLPXENSG00000166855.51579.830701982.42130-0.327502.120101.56250HepG2NCBP2
CLPXENSG00000166855.51338.931701821.85330-0.444305.987804.86810HepG2NOL12
CLPXENSG00000166855.51380.985901111.374000.313302.200801.53160HepG2NSUN2
CLPXENSG00000166855.51973.135701213.515100.701204.414203.27740HepG2PABPC1
CLPXENSG00000166855.5918.284401167.76220-0.346703.940402.94920HepG2PARN
CLPXENSG00000166855.51344.247201827.37040-0.443007.527706.60470HepG2PCBP1
CLPXENSG00000166855.5569.64770752.60650-0.401803.338201.98230HepG2PKM
CLPXENSG00000166855.5783.216301052.25080-0.426004.843403.89650HepG2PPIL4
CLPXENSG00000166855.51376.230501859.46890-0.434207.074906.28180HepG2PTBP1
CLPXENSG00000166855.51306.132801739.13090-0.413104.197403.48060HepG2PUF60
CLPXENSG00000166855.51401.343401846.17890-0.397707.962407.06380HepG2PUM1
CLPXENSG00000166855.5941.459301439.27600-0.6124013.2159012.04440HepG2PUS1
CLPXENSG00000166855.51438.158202013.74160-0.485707.168106.23150HepG2QKI
CLPXENSG00000166855.52005.362301553.528800.368204.225603.19280HepG2RBM15
CLPXENSG00000166855.51432.203402069.36780-0.5310010.405909.47910HepG2NELFE
CLPXENSG00000166855.51381.807001927.41210-0.480108.700807.69980HepG2RECQL
CLPXENSG00000166855.5700.48200885.55560-0.338202.365801.79280HepG2RPS19
CLPXENSG00000166855.51001.639001333.09360-0.412402.327001.59130HepG2RPS3A
CLPXENSG00000166855.5888.398301050.62870-0.242002.277901.68430HepG2SAFB2
CLPXENSG00000166855.51541.800001935.85530-0.328404.452903.72990HepG2SF3B4
CLPXENSG00000166855.51438.777601667.58540-0.212902.361301.70560HepG2SLBP
CLPXENSG00000166855.5980.173901225.21320-0.321904.353003.57850HepG2SMN1
CLPXENSG00000166855.51613.620602020.65130-0.324503.854903.31970HepG2SRSF1
CLPXENSG00000166855.51246.622301717.15600-0.462007.880806.89530HepG2SRSF5
CLPXENSG00000166855.51610.163101967.04580-0.288803.815503.23490HepG2SSB
CLPXENSG00000166855.51473.609001952.86440-0.406207.576206.63050HepG2SUCLG1
CLPXENSG00000166855.5839.334401221.70770-0.541605.300904.34290HepG2TARDBP
CLPXENSG00000166855.5701.679001146.36580-0.7082010.843009.96630HepG2TIAL1
CLPXENSG00000166855.5899.559301156.60270-0.362604.452803.77210HepG2TRIM56
CLPXENSG00000166855.51108.053501317.07100-0.249302.603101.92190HepG2UPF1
CLPXENSG00000166855.5578.478401077.54020-0.897403.988802.77400HepG2UPF2
CLPXENSG00000166855.5670.200201157.97350-0.788903.554302.74070HepG2XRN2
CLPXENSG00000166855.52712.024202034.146500.414807.210906.35790K562AGGF1
CLPXENSG00000166855.53032.282202116.655000.518507.184106.08880K562AKAP8L
CLPXENSG00000166855.52768.281602220.943600.317704.474903.28420K562ATP5C1
CLPXENSG00000166855.5519.21250702.76540-0.436703.153602.01130K562CCAR1
CLPXENSG00000166855.52257.945102647.57300-0.229702.504101.45480K562CPEB4
CLPXENSG00000166855.55173.541604336.175900.254602.758001.78500K562CELF1
CLPXENSG00000166855.51280.697501803.61420-0.494008.195907.05790K562EIF2S2
CLPXENSG00000166855.51461.286701818.83760-0.315802.559101.77080K562EIF4A3
CLPXENSG00000166855.51473.638001891.52090-0.360204.722403.96100K562FXR1
CLPXENSG00000166855.52694.618701971.342300.450803.073302.32180K562G3BP2
CLPXENSG00000166855.51810.984602403.49900-0.408404.653703.67440K562GRSF1
CLPXENSG00000166855.51031.319601487.99490-0.528906.311705.44560K562HNRNPC
CLPXENSG00000166855.53114.571702246.183000.471504.556103.45540K562KIF1C
CLPXENSG00000166855.52036.283302433.10000-0.256902.206601.39110K562MATR3
CLPXENSG00000166855.53024.572002516.308700.265302.604701.72700K562MBNL1
CLPXENSG00000166855.51615.792801940.41840-0.264103.335502.45120K562MTPAP
CLPXENSG00000166855.52747.961501763.760400.639602.079301.33670K562NAA15
CLPXENSG00000166855.51090.838101328.37230-0.284202.240601.51950K562POLR2G
CLPXENSG00000166855.5942.648001334.17530-0.501204.730303.50300K562PSIP1
CLPXENSG00000166855.51871.805702368.58170-0.339603.631802.88260K562PTBP1
CLPXENSG00000166855.53341.731804009.84980-0.263003.497202.41820K562PUM2
CLPXENSG00000166855.53406.711902098.902500.6986010.975509.94300K562PUS1
CLPXENSG00000166855.53124.057602045.261900.6110013.7753012.44800K562RBM15
CLPXENSG00000166855.51748.872702214.04220-0.340302.631401.30600K562RBM34
CLPXENSG00000166855.5870.928301217.41580-0.483205.225003.85700K562RCC2
CLPXENSG00000166855.51718.825702049.70440-0.254002.324801.54240K562SF3B4
CLPXENSG00000166855.5776.784201154.06170-0.571105.869004.21670K562SRFBP1
CLPXENSG00000166855.51224.436401674.82550-0.451905.015903.52500K562SRSF4
CLPXENSG00000166855.51378.539402350.09170-0.7696011.525209.92190K562TARDBP
CLPXENSG00000166855.51704.055802266.89090-0.411705.005903.85410K562TIA1
CLPXENSG00000166855.5976.414801283.23480-0.394202.807501.86380K562TIAL1
CLPXENSG00000166855.51834.440602224.15290-0.277902.272601.30440K562TRA2A
CLPXENSG00000166855.51794.566902286.01660-0.349205.941304.93360K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CLPX is not available on ENCORE database.





10 RBPs can affect the splicing of CLPX :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECLPXENSG00000166855.5chr15-654549416545498365450912654510896545636665456526-0.069000.000000.00033excludedK562AKAP8L
SECLPXENSG00000166855.5chr15-654458846544600565444767654448746544711965447419-0.061000.000250.00372excludedK562AQR
SECLPXENSG00000166855.5chr15-654491816544927065448029654481946545008365450267-0.266000.000000.00000excludedK562AQR
SECLPXENSG00000166855.5chr15-654549416545498365451024654510896545636665456526-0.072000.000280.00415excludedK562AQR
SECLPXENSG00000166855.5chr15-654549416545498365450912654510896545636665456526-0.142000.000000.00000excludedK562PUS1
SECLPXENSG00000166855.5chr15-654549416545498365450912654510896545636665456526-0.160000.000000.00001excludedK562U2AF1
SECLPXENSG00000166855.5chr15-654491156544927065448029654481946545008365450248-0.098000.002660.05474excludedHepG2SRSF1
SECLPXENSG00000166855.5chr15-654549416545498365450912654510896545636665456526-0.056000.000130.00734excludedK562UTP18
SECLPXENSG00000166855.5chr15-654491156544927065448029654481946545008365450248-0.088000.001470.04550excludedK562UTP18
SECLPXENSG00000166855.5chr15-654549416545498365450912654510896545636665456526-0.220000.000000.00000excludedK562U2AF2
SECLPXENSG00000166855.5chr15-654549416545498365451024654510896545636665456526-0.069000.000000.00026excludedK562RBM15
SECLPXENSG00000166855.5chr15-654549416545498365450912654510896545636665456526-0.107000.000000.00000excludedK562AGGF1
A3SSCLPXENSG00000166855.5chr15-6545008365450278654500836545024865450912654511580.067000.000000.00000longerK562AQR
A3SSCLPXENSG00000166855.5chr15-6545091265451158654509126545108965454941654550200.131000.000000.00000longerK562AQR
A3SSCLPXENSG00000166855.5chr15-6544911565449289654491156544927065450083654501680.078000.000000.00000longerK562AQR
A3SSCLPXENSG00000166855.5chr15-6547238165472594654723816547254265477412654775540.115000.000000.00000longerK562AQR
A3SSCLPXENSG00000166855.5chr15-654480296544825065448029654481946545008365450168-0.699000.001390.00936shorterK562AQR
A5SSCLPXENSG00000166855.5chr15-6544911565449270654491816544927065448029654481940.056000.000160.01747longerHepG2SF3A3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CLPX is not avaliable on ENCORE database.