CIAO1

General Information

Gene Name       : CIAO1
Gene ID             : ENSG00000144021.2
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CIAO1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CIAO1ENSG00000144021.231.6937.9634.83ENCSR000AEF
HepG2CIAO1ENSG00000144021.2100.5990.9795.78ENCSR985KAT
K562CIAO1ENSG00000144021.268.0669.7268.89ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CIAO1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CIAO1 RNA is bound by 25 proteins.  







eCLIP assay for CIAO1 is not avaliable on ENCORE database.





25 proteins are bound to CIAO1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr29693712896937197+3'-UTR3.130084.71502HepG2GRWD1
chr29693713296937242+3'-UTR3.133645.41277K562UCHL5
chr29693695996937091+3'-UTR,CDS3.695908.27517K562RBM15
chr29693713396937192+3'-UTR5.257446.73016HepG2SUB1
chr29693200496932098+5'-UTR,CDS4.483825.65659HepG2DDX3X
chr29693207996932145+5'-UTR,CDS4.810037.25648HepG2GRWD1
chr29693208596932141+5'-UTR,CDS3.8841712.00587K562DDX3X
chr29693198596932085+5'-UTR3.9053710.26816K562DDX3X
chr29693202796932224+5'-UTR,CDS4.1598010.65286HepG2RPS3
chr29693200796932180+5'-UTR,CDS4.168427.17313K562FMR1
chr29693206696932167+5'-UTR,CDS4.795426.40474K562GEMIN5
chr29693500496935033+CDS,intron-Proximal4.215673.88780HepG2G3BP1
chr29693335196933389+CDS,intron-Proximal3.662933.91876HepG2U2AF2
chr29693357996933650+CDS4.245235.23082K562DDX24
chr29693301396933066+CDS,intron-Distal,intron-Proximal3.632733.39008HepG2AQR
chr29693358296933658+CDS3.540893.69826K562TARDBP
chr29693319496933208+CDS,intron-Distal,intron-Proximal4.816384.16554HepG2PPIG
chr29693209896932228+CDS,intron-Proximal4.3172819.17963HepG2DDX3X
chr29693436696934398+CDS,intron-Proximal3.135433.47314HepG2G3BP1
chr29693222596932235+CDS,intron-Proximal5.8769111.46503HepG2PRPF8
chr29693494796935040+CDS,intron-Proximal4.1365810.56837K562SF3B4
chr29693316896933194+CDS,intron-Distal3.627123.64266HepG2PPIG
chr29693493596935021+CDS,intron-Proximal4.4192416.54943HepG2AQR
chr29693214196932210+CDS3.067515.03702K562DDX3X
chr29693208896932151+CDS3.352477.07011HepG2SRSF1
chr29693421896934297+CDS3.059623.70975K562UCHL5
chr29693222596932237+CDS,intron-Proximal5.139636.74224HepG2AQR
chr29693421796934317+CDS3.8966717.66512HepG2PPIG
chr29693689096936959+CDS3.343633.34822K562RBM15
chr29693698096936995+CDS4.738106.30966K562YBX3
chr29693431096934374+CDS3.753673.42611HepG2SRSF1
chr29693214596932213+CDS3.705635.80880HepG2GRWD1
chr29693339596933476+CDS,intron-Proximal3.073444.32134HepG2G3BP1
chr29693209596932149+CDS4.029563.62765K562SRSF1
chr29693221796932271+CDS,intron-Proximal4.667364.13847K562AQR
chr29693301896933109+CDS,intron-Distal,intron-Proximal4.028219.65424HepG2BUD13
chr29693318896933274+CDS,intron-Distal,intron-Proximal3.966108.47339HepG2PRPF8
chr29693680696936876+CDS,intron-Proximal4.443474.28193HepG2AQR
chr29693307096933146+CDS,intron-Distal4.150575.48791HepG2DDX3X
chr29693492196935010+CDS,intron-Proximal3.831537.45106HepG2RBM5
chr29693363696933719+CDS,intron-Proximal3.733125.13777HepG2PRPF8
chr29693433296934397+CDS,intron-Proximal3.033783.85381HepG2BCLAF1
chr29693699596937031+CDS5.041277.64008K562YBX3
chr29693215196932225+CDS4.329685.61940HepG2SRSF1
chr29693699196937029+CDS4.531784.84481HepG2PPIG
chr29693366096933711+CDS,intron-Proximal4.888895.65342K562AQR
chr29693680496936917+CDS,intron-Proximal3.155724.56061K562BUD13
chr29693474396934831+intron-Distal3.721013.00956K562HNRNPA1
chr29693469696934819+intron-Distal3.528619.21399HepG2GTF2F1
chr29693467896934734+intron-Distal4.1863212.39827HepG2PRPF4
chr29693469596934802+intron-Distal3.435009.14378K562GTF2F1
chr29693473496934798+intron-Distal3.449389.61680HepG2PRPF4
chr29693494096935001+intron-Proximal4.200693.70701HepG2PRPF4
chr29693226496932270+intron-Proximal3.548066.65114HepG2PRPF8
chr29693223796932263+intron-Proximal5.225577.45424HepG2AQR
chr29693368996933750+intron-Proximal4.127143.85435K562PRPF8
chr29693223596932264+intron-Proximal4.359639.38298HepG2PRPF8
chr29693368296933738+intron-Proximal3.387453.99201HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CIAO1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CIAO1 is not available on ENCORE database.

  • 67 RBPs can affect the levels of CIAO1.  








The Knockdown/knockout RNA-Seq assay for CIAO1 is not available on ENCORE database.





67 RBPs can affect the gene expression of CIAO1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CIAO1ENSG00000144021.22248.722101708.234100.396503.890803.19360HepG2BOP1
CIAO1ENSG00000144021.22416.355601888.522900.355507.187806.20830HepG2CKAP4
CIAO1ENSG00000144021.21254.759201568.24620-0.321702.468701.81420HepG2CPSF6
CIAO1ENSG00000144021.21508.605801147.005300.395203.369502.19130HepG2CSTF2
CIAO1ENSG00000144021.22229.519002598.39370-0.220902.330401.73190HepG2CELF1
CIAO1ENSG00000144021.21959.514501603.998500.288703.252302.00070HepG2DDX1
CIAO1ENSG00000144021.22126.624601665.721200.352303.649702.59010HepG2DDX24
CIAO1ENSG00000144021.21670.950002578.48690-0.625906.100005.21140HepG2DDX6
CIAO1ENSG00000144021.22018.035501516.980200.411604.226503.02600HepG2DHX30
CIAO1ENSG00000144021.22251.855301807.148200.317304.536803.70690HepG2DKC1
CIAO1ENSG00000144021.21368.736401559.03760-0.187802.015101.44200HepG2DNAJC2
CIAO1ENSG00000144021.23711.041302739.795500.437703.578402.85370HepG2EIF4A3
CIAO1ENSG00000144021.21378.118902667.30110-0.9527010.521409.22390HepG2EIF4B
CIAO1ENSG00000144021.22247.978302756.35330-0.294104.289003.28980HepG2EIF4G1
CIAO1ENSG00000144021.24346.291103410.967200.349507.118506.22920HepG2ETF1
CIAO1ENSG00000144021.22498.878001570.946200.669502.301301.38240HepG2FTO
CIAO1ENSG00000144021.22251.064702763.90400-0.296102.053001.45340HepG2FXR1
CIAO1ENSG00000144021.21601.317702564.15490-0.679207.640506.56090HepG2G3BP1
CIAO1ENSG00000144021.23486.299602721.880300.357003.015902.08570HepG2G3BP2
CIAO1ENSG00000144021.23197.872301777.713400.8470011.9631010.71280HepG2GPKOW
CIAO1ENSG00000144021.21445.326801803.36610-0.319304.318903.11520HepG2HDGF
CIAO1ENSG00000144021.22269.188801766.238100.361403.412102.64860HepG2HNRNPC
CIAO1ENSG00000144021.21414.751101754.55730-0.310604.221803.48630HepG2HNRNPU
CIAO1ENSG00000144021.21503.082401726.70140-0.200102.345801.40620HepG2KIF1C
CIAO1ENSG00000144021.22124.664501720.861600.304002.683801.88740HepG2MSI2
CIAO1ENSG00000144021.22128.550602770.34960-0.380205.172404.13510HepG2NOL12
CIAO1ENSG00000144021.22130.566501504.288600.502105.616304.57050HepG2NSUN2
CIAO1ENSG00000144021.21892.519002547.00800-0.428508.457307.49100HepG2PCBP1
CIAO1ENSG00000144021.22480.047401843.135800.428102.411201.43840HepG2PCBP2
CIAO1ENSG00000144021.21214.567701564.91650-0.365604.437303.52390HepG2PPIL4
CIAO1ENSG00000144021.22046.983701686.320400.279503.556802.68950HepG2PRPF4
CIAO1ENSG00000144021.22192.871402591.65300-0.241102.919002.36010HepG2PTBP1
CIAO1ENSG00000144021.22402.280202805.28510-0.223701.986801.41270HepG2PUM2
CIAO1ENSG00000144021.22233.687701923.939700.215302.659302.05130HepG2PUS1
CIAO1ENSG00000144021.21767.269502352.25920-0.412505.154004.02740HepG2RBM15
CIAO1ENSG00000144021.22951.958702207.347600.419304.320903.49720HepG2RPLP0
CIAO1ENSG00000144021.22275.223402698.28620-0.246003.256202.62110HepG2SF3B4
CIAO1ENSG00000144021.22644.766301868.404100.501203.028902.21050HepG2SNRNP70
CIAO1ENSG00000144021.22488.871403220.03880-0.371607.876507.15080HepG2SRFBP1
CIAO1ENSG00000144021.21307.634101806.84750-0.466503.156802.07800HepG2SRSF3
CIAO1ENSG00000144021.24129.294402795.766500.5626017.5217016.46490HepG2SSB
CIAO1ENSG00000144021.21899.584502326.10940-0.292202.792201.95220HepG2TIA1
CIAO1ENSG00000144021.22586.409101704.700200.6013011.1896010.30250HepG2TIAL1
CIAO1ENSG00000144021.22234.828801818.914600.297002.264501.69030HepG2U2AF1
CIAO1ENSG00000144021.21318.798501826.52190-0.469908.512507.58990K562AGGF1
CIAO1ENSG00000144021.21563.218102006.93020-0.360503.459402.33120K562AKAP8
CIAO1ENSG00000144021.21420.677101900.54410-0.419804.374903.54680K562AKAP8L
CIAO1ENSG00000144021.22337.552803114.35660-0.413904.385803.67870K562AQR
CIAO1ENSG00000144021.21756.271402034.86470-0.212402.451001.55040K562BCLAF1
CIAO1ENSG00000144021.21796.598302182.90680-0.281002.920601.70330K562CCDC124
CIAO1ENSG00000144021.21468.066701834.88710-0.321803.051402.22910K562CPSF6
CIAO1ENSG00000144021.24157.598302974.092700.4832011.7960010.55240K562DDX47
CIAO1ENSG00000144021.21797.257901385.427500.375404.796603.76370K562EIF3G
CIAO1ENSG00000144021.2896.407301170.17610-0.384504.104002.64850K562EIF4B
CIAO1ENSG00000144021.21255.617301582.42260-0.333702.297301.46840K562FTO
CIAO1ENSG00000144021.22059.536001351.383300.6078010.515909.42220K562FXR1
CIAO1ENSG00000144021.21114.117501424.81620-0.354903.115501.57290K562G3BP1
CIAO1ENSG00000144021.21402.754901751.86220-0.320602.655401.87570K562GPKOW
CIAO1ENSG00000144021.21920.078302386.66880-0.313803.735402.69610K562HNRNPU
CIAO1ENSG00000144021.21543.815402017.07410-0.385804.297603.23870K562KIF1C
CIAO1ENSG00000144021.21934.537301566.225800.304602.749701.91290K562MAGOH
CIAO1ENSG00000144021.21480.401601930.73740-0.383203.456802.21180K562MAK16
CIAO1ENSG00000144021.23207.144604001.74490-0.319302.758901.63180K562MSI2
CIAO1ENSG00000144021.21230.869601583.81610-0.363702.081401.33830K562NAA15
CIAO1ENSG00000144021.22172.892702435.10790-0.164402.242401.56400K562NSUN2
CIAO1ENSG00000144021.2996.039501721.44100-0.789304.029602.77780K562PABPN1
CIAO1ENSG00000144021.21347.265201663.16000-0.303902.083401.42870K562PRPF8
CIAO1ENSG00000144021.21864.102701521.719400.292702.659602.00650K562PTBP1
CIAO1ENSG00000144021.21330.004001885.06690-0.503205.455804.72520K562PUS1
CIAO1ENSG00000144021.21383.287001836.50760-0.408905.527104.71450K562RBM15
CIAO1ENSG00000144021.22140.592001694.152500.337302.250401.51760K562RPS19
CIAO1ENSG00000144021.21359.14400976.457700.477003.494102.35780K562RPS3
CIAO1ENSG00000144021.21316.578801666.09560-0.339702.184801.33180K562SF3B1
CIAO1ENSG00000144021.21799.572701491.842000.270502.284701.63480K562SRSF1
CIAO1ENSG00000144021.21120.104201429.10330-0.351503.789602.25520K562SSB
CIAO1ENSG00000144021.21264.675201610.36420-0.348602.236701.32880K562SUPV3L1
CIAO1ENSG00000144021.22104.481401782.505400.239502.102801.38590K562SYNCRIP
CIAO1ENSG00000144021.2822.229001072.49810-0.383402.323601.33290K562U2AF1
CIAO1ENSG00000144021.21314.591301704.33920-0.374602.887301.84210K562UCHL5
CIAO1ENSG00000144021.21737.688602209.33650-0.346403.590202.59420K562WDR3
CIAO1ENSG00000144021.22696.090902297.401600.230802.857401.99690K562WDR43
CIAO1ENSG00000144021.22552.972803508.75300-0.458805.309004.04800K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CIAO1 is not available on ENCORE database.





33 RBPs can affect the splicing of CIAO1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECIAO1ENSG00000144021.2chr2+969350059693509396934194969343969693684896937383-0.075000.000000.00008excludedHepG2U2AF1
SECIAO1ENSG00000144021.2chr2+969349939693509396934194969343969693684896939087-0.061000.002080.02607excludedHepG2U2AF2
SECIAO1ENSG00000144021.2chr2+969349939693509396934194969343969693684896939087-0.052000.004900.08708excludedHepG2SRSF1
A3SSCIAO1ENSG00000144021.2chr2+9693353896933662969335739693366296933362969334740.075000.000000.00027longerK562RBM22
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.254000.000000.00000includedK562SF3B4
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.064000.001950.08898includedHepG2TBRG4
RICIAO1ENSG00000144021.2chr2+969341949693509396934194969343969693500596935093-0.251000.000270.02171excludedK562DROSHA
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.166000.000000.00001includedHepG2PCBP2
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.108000.000620.00911includedHepG2SF3A3
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.106000.000000.00023includedHepG2TIA1
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.277000.000000.00000includedHepG2PRPF8
RICIAO1ENSG00000144021.2chr2+969341949693509396934194969343969693500596935093-0.130000.000040.00180excludedK562SRSF1
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.115000.000000.00101includedK562PHF6
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.146000.000010.00033includedK562PRPF8
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.081000.000060.00270includedHepG2IGF2BP3
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.091000.000010.00100includedHepG2MATR3
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.377000.000000.00004includedHepG2FTO
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.171000.000000.00000includedHepG2PCBP1
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.075000.000010.00062includedHepG2SRSF1
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.091000.000000.00002includedHepG2QKI
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.101000.000010.00145includedHepG2HNRNPA1
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.128000.000000.00010includedHepG2NKRF
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.084000.000920.06881includedK562AARS
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.192000.000000.00021includedK562RBM22
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.124000.000000.00000includedHepG2TAF15
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.178000.000000.00000includedHepG2G3BP1
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.106000.000000.00009includedHepG2KHSRP
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.168000.006470.06975includedK562U2AF2
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.225000.000000.00000includedHepG2TIAL1
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.073000.000160.00320includedHepG2NCBP2
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.076000.001950.08526includedHepG2HNRNPU
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.199000.000000.00000includedHepG2SF3B4
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.148000.000000.00000includedHepG2FUBP3
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.164000.000000.00000includedHepG2RBM22
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.101000.000000.00007includedHepG2SRSF9
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.090000.000010.00014includedHepG2HNRNPK
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.087000.000010.00096includedHepG2PTBP1
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.130000.000000.00005includedHepG2SUGP2
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.205000.000000.00000includedK562EFTUD2
RICIAO1ENSG00000144021.2chr2+9693419496935093969341949693439696935005969350930.261000.000000.00000includedK562AQR
RICIAO1ENSG00000144021.2chr2+969341949693509396934194969343969693500596935093-0.117000.000150.00485excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CIAO1 is not avaliable on ENCORE database.