C6orf89

General Information

Gene Name       : C6orf89
Gene ID             : ENSG00000198663.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C6orf89)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C6orf89ENSG00000198663.1628.9029.0428.97ENCSR000AEF
HepG2C6orf89ENSG00000198663.1616.7522.7819.77ENCSR985KAT
K562C6orf89ENSG00000198663.1669.4474.8872.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C6orf89 is not avaliable on ENCORE database.



Proteins bound to RNA
  • C6orf89 RNA is bound by 25 proteins.  







eCLIP assay for C6orf89 is not avaliable on ENCORE database.





25 proteins are bound to C6orf89 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63689196336891997+3'-UTR4.0127413.63856K562IGF2BP2
chr63686999536870085+3'-UTR,CDS,intron-Proximal4.154178.71486K562IGF2BP1
chr63686723636867373+3'-UTR,CDS3.724336.61694K562GRWD1
chr63689195836892035+3'-UTR4.815767.09156HepG2IGF2BP1
chr63689194736891997+3'-UTR3.065184.25081K562FAM120A
chr63689189136891951+3'-UTR3.595537.44034HepG2AKAP1
chr63689194736892035+3'-UTR3.319174.61266K562IGF2BP1
chr63689205836892156+3'-UTR4.4535316.16162K562UPF1
chr63686995836870004+3'-UTR,CDS,intron-Proximal4.784594.13847K562AQR
chr63686726536867325+3'-UTR,CDS3.7709224.47255K562DDX3X
chr63689199736892031+3'-UTR4.7853618.28102K562IGF2BP2
chr63689189936891958+3'-UTR5.6650014.63173HepG2IGF2BP1
chr63689163036891656+3'-UTR3.234803.67576K562IGF2BP2
chr63686720836867255+3'-UTR,5'-UTR,CDS3.046355.26696K562UCHL5
chr63689142936891465+3'-UTR3.806633.05875K562RBM15
chr63689190436891953+3'-UTR3.2744814.52417K562TIA1
chr63686726936867311+3'-UTR,CDS4.023583.73926K562RBM15
chr63689132636891395+3'-UTR3.289293.77005HepG2AKAP1
chr63689215636892262+3'-UTR3.2014911.57789K562UPF1
chr63689190036891977+3'-UTR4.028778.14483HepG2PCBP2
chr63686720036867261+3'-UTR,5'-UTR,CDS,intron-Proximal4.9416435.83806K562DDX3X
chr63689195136892019+3'-UTR4.692965.45170HepG2AKAP1
chr63686737036867380+3'-UTR,CDS4.000063.18462K562IGF2BP2
chr63689160536891654+3'-UTR4.134203.45012HepG2UPF1
chr63689203536892125+3'-UTR3.700386.58529HepG2UPF1
chr63689178436891849+3'-UTR3.689715.05222K562IGF2BP1
chr63689189836891963+3'-UTR5.1193935.62467K562IGF2BP2
chr63689189936891958+3'-UTR4.354184.38226HepG2IGF2BP3
chr63689133236891417+3'-UTR4.439828.55060HepG2UPF1
chr63689189036892035+3'-UTR4.9433020.91166HepG2UPF1
chr63689203136892043+3'-UTR3.817645.73934K562IGF2BP2
chr63689195836892041+3'-UTR4.006993.77064HepG2IGF2BP3
chr63689208636892195+3'-UTR3.048983.36366K562LIN28B
chr63689189336892006+3'-UTR4.341796.34161K562PCBP1
chr63685373736853804+5'-UTR,CDS,intron-Distal6.8965017.98109HepG2DDX3X
chr63685373636853805+5'-UTR,CDS,intron-Distal,intron-Proximal5.4529228.29638K562DDX3X
chr63688731236887368+CDS,intron-Proximal3.570948.61736K562U2AF1
chr63688246636882488+CDS,intron-Proximal3.486077.65545K562AQR
chr63688731336887417+CDS,intron-Proximal3.789927.61543HepG2U2AF2
chr63689112236891147+CDS,intron-Proximal4.367224.06516HepG2SND1
chr63688733936887376+CDS,intron-Proximal4.3559319.34854K562U2AF2
chr63689111336891159+CDS,intron-Proximal3.640074.11428K562U2AF1
chr63688743436887478+CDS,intron-Proximal4.415184.94988HepG2SND1
chr63688218136882211+CDS3.436075.65349K562UCHL5
chr63687018636870241+CDS,intron-Proximal4.509744.35676HepG2PRPF8
chr63688735636887434+CDS4.935976.50673HepG2SND1
chr63685380436853873+intron-Distal,intron-Proximal5.066316.75320K562AQR
chr63687874536878823+intron-Distal3.619394.94630K562QKI
chr63688528036885358+intron-Distal3.259165.01300K562RBFOX2
chr63689101136891074+intron-Distal,intron-Proximal4.274654.32536HepG2SF3B4
chr63687114336871223+intron-Distal3.855033.71397K562KHSRP
chr63689100736891081+intron-Distal,intron-Proximal4.8997316.99801K562SF3B4
chr63688579736885886+intron-Distal4.722574.57222K562HNRNPK
chr63686103036861167+intron-Distal3.201053.61097K562ILF3
chr63688731036887339+intron-Proximal4.1111814.45891K562U2AF2
chr63688249636882520+intron-Proximal4.259226.80869K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C6orf89 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C6orf89 is not available on ENCORE database.

  • 93 RBPs can affect the levels of C6orf89.  








The Knockdown/knockout RNA-Seq assay for C6orf89 is not available on ENCORE database.





93 RBPs can affect the gene expression of C6orf89 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C6orf89ENSG00000198663.122348.492903660.80240-0.640406.606205.82360HepG2AKAP1
C6orf89ENSG00000198663.122430.562501860.057700.385806.644305.50880HepG2AKAP8L
C6orf89ENSG00000198663.123282.704602532.161800.374407.048606.03350HepG2AUH
C6orf89ENSG00000198663.122067.799601455.955800.506004.454303.33730HepG2BCLAF1
C6orf89ENSG00000198663.122044.395401638.951900.318803.375902.53420HepG2CALR
C6orf89ENSG00000198663.122697.725401850.971900.5434016.1980014.87280HepG2CKAP4
C6orf89ENSG00000198663.122547.741101790.804800.508502.906902.12260HepG2CNOT7
C6orf89ENSG00000198663.121972.353001472.970900.421103.982403.17150HepG2CPSF6
C6orf89ENSG00000198663.121330.224501604.18760-0.270202.724801.71600HepG2YBX3
C6orf89ENSG00000198663.122864.924102244.812500.351807.695106.54760HepG2DAZAP1
C6orf89ENSG00000198663.123081.095501612.708300.9339016.9330015.42870HepG2DDX21
C6orf89ENSG00000198663.121997.232301577.321100.340403.310002.30640HepG2DDX24
C6orf89ENSG00000198663.122622.570101745.810600.587007.326605.75370HepG2DDX5
C6orf89ENSG00000198663.122072.796303012.14360-0.539204.820904.02600HepG2DDX6
C6orf89ENSG00000198663.122605.148001771.203800.5565013.0819011.83150HepG2DKC1
C6orf89ENSG00000198663.122049.236001572.531200.381903.114602.14050HepG2EEF2
C6orf89ENSG00000198663.123549.203602896.030900.293302.071901.55080HepG2EIF2S1
C6orf89ENSG00000198663.121595.305301276.503800.321502.310301.47730HepG2EIF3D
C6orf89ENSG00000198663.122410.290603115.91790-0.370502.097201.49450HepG2EIF4B
C6orf89ENSG00000198663.122870.490102121.529600.436104.548603.52080HepG2EIF4G2
C6orf89ENSG00000198663.122152.547703228.74980-0.584906.761505.70950HepG2FXR1
C6orf89ENSG00000198663.122305.776801664.352100.470204.286903.01280HepG2GNB2L1
C6orf89ENSG00000198663.122081.882301669.767800.318102.084601.52500HepG2GPKOW
C6orf89ENSG00000198663.122745.768501768.932400.634209.503808.28210HepG2HNRNPC
C6orf89ENSG00000198663.121702.422903032.45840-0.8329014.4218012.94960HepG2HNRNPK
C6orf89ENSG00000198663.121713.088202044.83380-0.255403.712802.93970HepG2HNRNPL
C6orf89ENSG00000198663.123287.153901593.486501.0446020.7091019.23860HepG2HNRNPLL
C6orf89ENSG00000198663.123708.927503044.899000.284502.049201.45890HepG2IGF2BP2
C6orf89ENSG00000198663.121670.357202857.08260-0.774403.157402.10410HepG2IGF2BP3
C6orf89ENSG00000198663.122528.368403248.04310-0.361402.531701.92590HepG2MATR3
C6orf89ENSG00000198663.122362.220301743.559800.438005.169104.09010HepG2MSI2
C6orf89ENSG00000198663.122193.657201625.060600.432702.480701.56640HepG2MTPAP
C6orf89ENSG00000198663.122445.533303324.62710-0.443003.840003.09930HepG2NCBP2
C6orf89ENSG00000198663.123754.963802961.138800.342502.663001.95410HepG2PABPC4
C6orf89ENSG00000198663.123444.293802945.154300.225802.947802.32420HepG2PCBP1
C6orf89ENSG00000198663.121700.194501270.851400.419803.320102.44290HepG2PRPF8
C6orf89ENSG00000198663.122785.592902124.885500.390504.389303.65880HepG2PUF60
C6orf89ENSG00000198663.123161.729701885.670300.7455027.9262026.34730HepG2PUS1
C6orf89ENSG00000198663.123763.344303245.668900.213402.093101.53820HepG2QKI
C6orf89ENSG00000198663.123860.846402945.610500.390304.796103.93060HepG2RBM25
C6orf89ENSG00000198663.122080.115703335.14090-0.6811020.7653019.55210HepG2NELFE
C6orf89ENSG00000198663.122244.471903106.15080-0.4688010.728009.63630HepG2RECQL
C6orf89ENSG00000198663.122754.956502222.428300.309802.776102.09230HepG2RPLP0
C6orf89ENSG00000198663.122646.340001818.310200.541303.487502.42670HepG2RPS10
C6orf89ENSG00000198663.121856.456801246.609200.574406.361504.95090HepG2SERBP1
C6orf89ENSG00000198663.121583.039202356.59080-0.574004.616603.73280HepG2SF3A3
C6orf89ENSG00000198663.122121.907501577.260200.427804.286103.42540HepG2SF3B1
C6orf89ENSG00000198663.122574.648403120.10030-0.277204.226803.52040HepG2SF3B4
C6orf89ENSG00000198663.122399.808701754.970200.451402.537701.79000HepG2SNRNP70
C6orf89ENSG00000198663.122065.094703256.67040-0.6572021.2573020.20600HepG2SRSF1
C6orf89ENSG00000198663.122368.161902649.44150-0.161901.805701.34250HepG2SRSF9
C6orf89ENSG00000198663.123458.674402382.910700.5374015.1710014.16520HepG2SSB
C6orf89ENSG00000198663.122119.305402386.02760-0.171001.920501.38450HepG2SUCLG1
C6orf89ENSG00000198663.122273.176401454.694700.6439010.531908.81030HepG2SUPT6H
C6orf89ENSG00000198663.122052.429901640.029000.323502.056301.46040HepG2SUPV3L1
C6orf89ENSG00000198663.122420.045401553.048600.639808.816507.62550HepG2TARDBP
C6orf89ENSG00000198663.122972.858101707.593400.7998019.3648018.26020HepG2TIAL1
C6orf89ENSG00000198663.12608.44600968.80610-0.671106.564005.38370HepG2UCHL5
C6orf89ENSG00000198663.123048.744102089.932700.5447015.1056013.72580HepG2UPF1
C6orf89ENSG00000198663.121475.308002017.75260-0.451708.506607.54930HepG2UTP3
C6orf89ENSG00000198663.122134.644801654.986300.367106.918005.93430HepG2ZC3H8
C6orf89ENSG00000198663.123456.421402298.530200.5885022.5180021.32790HepG2ZNF622
C6orf89ENSG00000198663.124449.488806794.69430-0.6108022.2045020.70400K562AGGF1
C6orf89ENSG00000198663.125809.247107466.11180-0.362004.070002.82750K562AKAP8
C6orf89ENSG00000198663.125811.510307070.13080-0.282802.688402.04450K562AKAP8L
C6orf89ENSG00000198663.126248.137907549.76430-0.273002.678601.45830K562APOBEC3C
C6orf89ENSG00000198663.125306.352806649.20710-0.325503.450602.81020K562AQR
C6orf89ENSG00000198663.126288.645907418.16220-0.238303.051602.09310K562ATP5C1
C6orf89ENSG00000198663.123295.339704032.00910-0.291102.320101.52800K562BOP1
C6orf89ENSG00000198663.123086.987804287.11480-0.473807.225605.94990K562CPSF6
C6orf89ENSG00000198663.123040.050903746.29500-0.301404.696902.96130K562DDX27
C6orf89ENSG00000198663.124531.999806574.99100-0.5368016.0537014.60150K562DDX47
C6orf89ENSG00000198663.122914.410604109.25930-0.495704.892902.68170K562DDX51
C6orf89ENSG00000198663.126038.857607608.32220-0.333305.908404.56190K562DKC1
C6orf89ENSG00000198663.122981.323503804.72530-0.351803.175502.19270K562EFTUD2
C6orf89ENSG00000198663.124227.455004954.96260-0.229102.934402.19700K562EIF2S2
C6orf89ENSG00000198663.121888.541702925.72040-0.631504.213102.94630K562EIF3A
C6orf89ENSG00000198663.123023.462803739.78660-0.306804.318003.33500K562EIF3G
C6orf89ENSG00000198663.123313.504304002.83660-0.272703.916103.21460K562FXR1
C6orf89ENSG00000198663.122998.322103814.48620-0.347302.749601.33740K562GEMIN5
C6orf89ENSG00000198663.125102.925706602.92030-0.371804.929003.92230K562GRSF1
C6orf89ENSG00000198663.124363.638405198.97990-0.252702.506801.48370K562HNRNPA1
C6orf89ENSG00000198663.124846.986605757.23930-0.248303.141602.19270K562HNRNPU
C6orf89ENSG00000198663.125024.854706124.34800-0.285502.500701.74080K562HSPD1
C6orf89ENSG00000198663.126279.030607503.37430-0.257002.196701.47210K562KIF1C
C6orf89ENSG00000198663.123749.746005040.40330-0.426705.634104.42330K562MAGOH
C6orf89ENSG00000198663.125956.964607182.41460-0.269902.550201.53300K562MAK16
C6orf89ENSG00000198663.126156.435808405.64680-0.449307.102205.51930K562MBNL1
C6orf89ENSG00000198663.123253.717503995.33100-0.296202.860201.96720K562METAP2
C6orf89ENSG00000198663.124620.007205163.87410-0.160602.131401.41620K562MTPAP
C6orf89ENSG00000198663.123618.566004484.59620-0.309603.055202.02740K562PCBP2
C6orf89ENSG00000198663.122218.645303702.43440-0.7388011.7359010.18180K562PRPF8
C6orf89ENSG00000198663.123544.923304897.11440-0.466207.168606.13740K562PTBP1
C6orf89ENSG00000198663.127108.206709335.42390-0.393204.938203.85140K562PUF60
C6orf89ENSG00000198663.124186.639907012.03530-0.7440013.6572012.49680K562PUS1
C6orf89ENSG00000198663.125924.741906831.83600-0.205502.345501.79210K562RBM15
C6orf89ENSG00000198663.123387.795904695.40500-0.470905.855604.57330K562RBM22
C6orf89ENSG00000198663.121694.999803771.38510-1.1538020.5817018.38720K562RPS19
C6orf89ENSG00000198663.123103.709703779.86890-0.284302.736701.66190K562SAFB
C6orf89ENSG00000198663.124428.427305661.47840-0.354406.236805.05000K562SF3A3
C6orf89ENSG00000198663.122936.331703843.35220-0.388405.350904.13630K562SF3B4
C6orf89ENSG00000198663.122808.844003584.82640-0.351902.601401.61860K562SUPV3L1
C6orf89ENSG00000198663.123301.494004255.03740-0.366104.906803.80660K562SYNCRIP
C6orf89ENSG00000198663.124436.874205413.18150-0.286906.087104.88390K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C6orf89 is not available on ENCORE database.





10 RBPs can affect the splicing of C6orf89 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC6orf89ENSG00000198663.12chr6+3686227936862379368536293685380436867201368674090.226000.000010.00476includedK562MATR3
SEC6orf89ENSG00000198663.12chr6+368622793686237936853629368538043686720136867409-0.232000.000020.00461excludedHepG2DDX59
SEC6orf89ENSG00000198663.12chr6+3686227936862379368536293685380436867201368674090.153000.003520.04008includedHepG2U2AF2
SEC6orf89ENSG00000198663.12chr6+368622793686237936853629368538043686720136867409-0.130000.003170.04378excludedK562PUS1
SEC6orf89ENSG00000198663.12chr6+3686227936862379368536293685380436867201368674090.335000.000100.00713includedHepG2MATR3
SEC6orf89ENSG00000198663.12chr6+3686227936862379368536293685380436867201368674090.209000.000410.07876includedK562SAFB
SEC6orf89ENSG00000198663.12chr6+3686054136860632368536393685380436867201368674090.063000.003410.05156includedK562HNRNPC
A3SSC6orf89ENSG00000198663.12chr6+368873533688747736887388368874773688422036884350-0.054000.000560.03312shorterK562SF3B4
A3SSC6orf89ENSG00000198663.12chr6+368699963687021036870055368702103686720136867409-0.068000.006840.03800shorterK562AQR
A5SSC6orf89ENSG00000198663.12chr6+368672013686740936867201368672803687005536870210-0.089000.000070.01660shorterK562SUPV3L1
MXEC6orf89ENSG00000198663.12chr6+36867201368674093686999636870210368622793686237936882059368822110.137000.000110.014031includedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C6orf89 is not avaliable on ENCORE database.