YTHDF1

General Information

Gene Name       : YTHDF1
Gene ID             : ENSG00000149658.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: YTHDF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878YTHDF1ENSG00000149658.1714.7116.8315.77ENCSR000AEF
HepG2YTHDF1ENSG00000149658.1744.1541.5242.84ENCSR985KAT
K562YTHDF1ENSG00000149658.1722.8319.7221.27ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
YTHDF1293TshRNAYTHDF1-BG293LV05-25,YTHDF1-BG293LV05-26NT-BG293LV05-1,NT-BG293LV05-2,SubmittingENCORE2
YTHDF1293TshRNABG293LV05-27,BG293LV05-28BG293LV05-1,BG293LV05-2NotSatisfiedENCORE2
YTHDF1293TshRNAYTHDF1-BG293LV06-63B,YTHDF1-BG293LV06-64BNT-BG293LV06-1B,NT-BG293LV06-2B,SequencedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for YTHDF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • YTHDF1 RNA is bound by 26 proteins.  







eCLIP assay for YTHDF1 is not avaliable on ENCORE database.





26 proteins are bound to YTHDF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr206182743061827483-3'-UTR,intron-Distal3.080015.02670K562ZC3H11A
chr206182715861827214-3'-UTR,intron-Distal3.4402810.63469K562PUM2
chr206182804161828094-3'-UTR,CDS,intron-Distal3.823763.77215K562U2AF2
chr206182741361827482-3'-UTR,intron-Distal3.928583.82343K562HNRNPC
chr206182778861827890-3'-UTR,intron-Distal,intron-Proximal4.9453215.57236K562PUM2
chr206182779161827842-3'-UTR,intron-Distal,intron-Proximal3.316544.46783HepG2FUBP3
chr206182723361827286-3'-UTR,intron-Distal3.007673.66204K562TIA1
chr206182742061827474-3'-UTR,intron-Distal3.528773.04397HepG2TIA1
chr206182804661828095-3'-UTR,CDS,intron-Distal5.209318.22784HepG2U2AF2
chr206184730361847358-5'-UTR,intron-Distal3.1180410.34640HepG2DDX3X
chr206184737161847451-5'-UTR,intron-Distal4.2965010.68796HepG2DDX3X
chr206184723161847303-5'-UTR,CDS,intron-Distal3.5719519.58341HepG2DDX3X
chr206184729261847338-5'-UTR,intron-Distal5.063404.54356K562DDX3X
chr206184722161847292-5'-UTR,CDS,intron-Distal3.891674.08283K562DDX3X
chr206183493761834980-CDS,intron-Distal5.221078.63033K562RBM15
chr206184525961845331-CDS,intron-Distal,intron-Proximal3.575887.15565HepG2BUD13
chr206184523961845319-CDS,intron-Distal,intron-Proximal4.736877.37992K562GPKOW
chr206183460961834622-CDS,intron-Distal4.078768.68374K562YBX3
chr206183456361834617-CDS,intron-Distal4.431563.80461HepG2RBM15
chr206184524461845306-CDS,intron-Distal,intron-Proximal3.274596.93851K562BUD13
chr206183362761833687-CDS,intron-Distal,intron-Proximal5.7048611.79327K562RBM15
chr206184522861845332-CDS,intron-Distal,intron-Proximal3.620295.70176HepG2AQR
chr206184720861847230-CDS,intron-Distal5.3224031.98184HepG2PRPF8
chr206183389661833953-CDS,intron-Distal3.995495.76695HepG2RBM15
chr206184720761847219-CDS,intron-Distal4.7150415.39196HepG2AQR
chr206184693661847018-CDS,intron-Distal,intron-Proximal3.6110414.64172K562BUD13
chr206184694861847018-CDS,intron-Distal,intron-Proximal5.4865918.92803HepG2AQR
chr206183503561835098-CDS,intron-Distal3.488188.41541K562RBM15
chr206184520161845318-CDS,intron-Distal,intron-Proximal3.145829.64380K562AQR
chr206183407361834112-CDS,intron-Distal4.039793.51664K562RBM15
chr206183361761833659-CDS,intron-Distal,intron-Proximal3.374984.19468HepG2SRSF1
chr206183360061833668-CDS,intron-Distal,intron-Proximal3.267418.37988HepG2BUD13
chr206183389661833954-CDS,intron-Distal5.255849.50640K562RBM15
chr206184691761846936-CDS,intron-Distal,intron-Proximal4.5917920.65070HepG2PRPF8
chr206183365961833668-CDS,intron-Distal3.979873.61584HepG2SRSF1
chr206184686761846930-CDS,intron-Distal,intron-Proximal6.3024041.10395K562AQR
chr206183361161833682-CDS,intron-Distal,intron-Proximal3.107784.51003HepG2PPIG
chr206184694761847013-CDS,intron-Distal,intron-Proximal3.6709124.80905HepG2PRPF8
chr206184694461847017-CDS,intron-Distal,intron-Proximal7.3878566.56331K562AQR
chr206184717161847223-CDS,intron-Distal3.141148.21196K562BUD13
chr206184715061847221-CDS,intron-Distal4.706936.62427HepG2XRN2
chr206183467061834731-CDS,intron-Distal4.775936.83406K562RBM15
chr206184717061847208-intron-Distal5.2800342.25124HepG2PRPF8
chr206183746961837542-intron-Distal3.958653.27946HepG2HNRNPM
chr206184686261846929-intron-Distal,intron-Proximal4.908234.69961K562SF3B4
chr206184142061841499-intron-Distal4.057413.07008K562NONO
chr206184711061847173-intron-Distal3.863515.72235K562GEMIN5
chr206184709361847180-intron-Distal3.8386015.65308HepG2BUD13
chr206184710961847171-intron-Distal3.600559.59042K562PRPF8
chr206184717761847207-intron-Distal5.7016623.98694HepG2AQR
chr206184706361847168-intron-Distal4.1005816.29546K562EFTUD2
chr206184708061847170-intron-Distal4.1898734.59166HepG2PRPF8
chr206184683061846929-intron-Distal,intron-Proximal3.234658.81610K562PRPF8
chr206184508561845177-intron-Distal,intron-Proximal3.950973.22073HepG2KHSRP
chr206184710061847174-intron-Distal5.5120848.70830K562AQR
chr206184720961847218-intron-Distal5.4077834.34521K562AQR
chr206183359561833625-intron-Distal,intron-Proximal3.366778.45537HepG2PRPF8
chr206184226461842314-intron-Distal4.108963.07008K562NONO
chr206184101461841069-intron-Distal3.434897.12384HepG2HNRNPC
chr206184695461847016-intron-Distal,intron-Proximal3.4161812.32496HepG2EFTUD2
chr206184706861847171-intron-Distal3.3531613.37162K562BUD13
chr206184710461847177-intron-Distal5.4096818.56826HepG2AQR
chr206184143561841524-intron-Distal3.933083.43975HepG2LIN28B
chr206184229461842388-intron-Distal4.874843.79026K562HNRNPM
chr206184683961846890-intron-Distal,intron-Proximal4.644317.03763K562EFTUD2
chr206184508661845187-intron-Distal,intron-Proximal3.626838.44734K562KHSRP
chr206184482361844876-intron-Distal3.185463.53873HepG2HNRNPM
chr206184144661841518-intron-Distal4.382145.00488K562LIN28B
chr206184688461846917-intron-Distal,intron-Proximal4.9079821.80513HepG2PRPF8
chr206183895261839053-intron-Distal3.788137.24726HepG2HNRNPM
chr206184326261843342-intron-Distal4.429695.18738K562TARDBP
chr206184705761847176-intron-Distal3.528995.77260K562XRN2
chr206184717161847211-intron-Distal4.245666.15234K562PRPF8
chr206184684961846929-intron-Distal,intron-Proximal5.0294529.20562HepG2EFTUD2
chr206184435061844390-intron-Distal3.728783.16028HepG2SUGP2
chr206184490061844969-intron-Distal4.462098.19743HepG2HNRNPM
chr206184704261847080-intron-Distal,intron-Proximal3.691565.88049HepG2EFTUD2
chr206184717461847209-intron-Distal5.5812248.14426K562AQR
chr206184695361847001-intron-Distal,intron-Proximal3.142974.91779HepG2SUPV3L1
chr206183896161839058-intron-Distal3.430894.80898K562HNRNPM
chr206184709261847196-intron-Distal4.7508849.73950HepG2EFTUD2
chr206183359461833639-intron-Distal,intron-Proximal5.360597.81430K562AQR
chr206184480761844874-intron-Distal3.427923.59509K562HNRNPM
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for YTHDF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for YTHDF1 is not available on ENCORE database.

  • 71 RBPs can affect the levels of YTHDF1.  








The Knockdown/knockout RNA-Seq assay for YTHDF1 is not available on ENCORE database.





71 RBPs can affect the gene expression of YTHDF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
YTHDF1ENSG00000149658.131956.128501563.891900.322805.052404.27860HepG2ACO1
YTHDF1ENSG00000149658.131486.420402220.11450-0.578805.133304.43690HepG2AKAP1
YTHDF1ENSG00000149658.131876.061001571.287500.255702.974802.18240HepG2AKAP8L
YTHDF1ENSG00000149658.132088.113502474.05260-0.244702.857302.16140HepG2AUH
YTHDF1ENSG00000149658.131107.669801402.53270-0.340502.316101.49610HepG2BCLAF1
YTHDF1ENSG00000149658.132423.727901948.026800.315102.709402.11630HepG2BOP1
YTHDF1ENSG00000149658.132165.362301563.609800.4696011.116109.96400HepG2CKAP4
YTHDF1ENSG00000149658.132679.950301659.045600.691804.961703.93230HepG2CNOT7
YTHDF1ENSG00000149658.131402.859001788.40060-0.350302.752002.06680HepG2CPSF6
YTHDF1ENSG00000149658.132614.681001985.181400.397306.846305.92150HepG2CELF1
YTHDF1ENSG00000149658.131766.625902134.38970-0.272804.127403.25070HepG2DAZAP1
YTHDF1ENSG00000149658.131628.895601211.190700.427404.139203.32520HepG2DDX21
YTHDF1ENSG00000149658.134110.053502840.500000.5329013.7435012.56740HepG2ETF1
YTHDF1ENSG00000149658.132666.732002049.755000.379502.919702.12910HepG2FIP1L1
YTHDF1ENSG00000149658.131582.466901193.842800.406503.866603.12110HepG2HNRNPA1
YTHDF1ENSG00000149658.131675.490801944.21480-0.214602.691102.02620HepG2HNRNPL
YTHDF1ENSG00000149658.131451.117701934.69540-0.414903.558002.85410HepG2HNRNPLL
YTHDF1ENSG00000149658.131565.387301319.145300.246802.749602.14440HepG2HNRNPU
YTHDF1ENSG00000149658.131561.251901347.464200.212402.629601.91320HepG2ILF2
YTHDF1ENSG00000149658.133701.580102565.192500.529004.259803.22410HepG2LARP4
YTHDF1ENSG00000149658.131717.028401348.871000.348103.024101.75370HepG2LIN28B
YTHDF1ENSG00000149658.132013.720501659.017800.279402.391801.63660HepG2MSI2
YTHDF1ENSG00000149658.131718.267101305.734300.396004.391903.35460HepG2PARN
YTHDF1ENSG00000149658.132024.774001744.966500.214502.358401.78880HepG2PCBP1
YTHDF1ENSG00000149658.131169.616301534.79740-0.392005.418804.37100HepG2PRPF4
YTHDF1ENSG00000149658.132039.731001775.594300.200002.158201.66360HepG2PTBP1
YTHDF1ENSG00000149658.131548.835102020.39790-0.383503.765803.08230HepG2PUF60
YTHDF1ENSG00000149658.132844.136802144.795900.4071010.904609.89090HepG2PUM1
YTHDF1ENSG00000149658.132629.709502143.195500.295003.316902.58350HepG2PUM2
YTHDF1ENSG00000149658.132698.200402374.141400.184501.785501.34550HepG2RBM22
YTHDF1ENSG00000149658.131878.915201164.714600.6898010.905609.78240HepG2RPS19
YTHDF1ENSG00000149658.131974.416401428.518100.466804.704003.67520HepG2RPS2
YTHDF1ENSG00000149658.133497.318402109.501200.729206.939105.83730HepG2SF3A3
YTHDF1ENSG00000149658.131989.855801369.973900.5384014.2958013.01170HepG2SMN1
YTHDF1ENSG00000149658.132451.001501929.532800.345005.874405.24960HepG2SRSF1
YTHDF1ENSG00000149658.132459.646801994.913800.302004.662503.88600HepG2SRSF5
YTHDF1ENSG00000149658.131845.517902129.87150-0.206702.227001.59580HepG2SRSF7
YTHDF1ENSG00000149658.132170.917301449.875000.582304.701803.22900HepG2STIP1
YTHDF1ENSG00000149658.131260.232101868.83160-0.568402.376101.38720HepG2TBRG4
YTHDF1ENSG00000149658.13812.655701058.91590-0.381902.581501.61550HepG2TFIP11
YTHDF1ENSG00000149658.131878.927901281.814900.551608.475207.68620HepG2TIAL1
YTHDF1ENSG00000149658.132403.907401973.931900.284202.769701.89620HepG2TUFM
YTHDF1ENSG00000149658.132778.370901753.477800.663909.168208.01670HepG2U2AF1
YTHDF1ENSG00000149658.131628.529701870.80520-0.200102.186101.55310HepG2UPF1
YTHDF1ENSG00000149658.132497.764801806.188700.4676010.358809.31700HepG2UTP3
YTHDF1ENSG00000149658.131265.607001555.25750-0.297302.107601.46690HepG2XRN2
YTHDF1ENSG00000149658.135507.911401887.630001.5448052.8690050.60960K562AQR
YTHDF1ENSG00000149658.133823.301302976.951100.360904.735803.44970K562CELF1
YTHDF1ENSG00000149658.132095.054101737.219400.270102.780801.56570K562DDX21
YTHDF1ENSG00000149658.132629.312301986.759100.404207.373306.37880K562DDX47
YTHDF1ENSG00000149658.131221.84830988.764400.305303.034201.64860K562DDX6
YTHDF1ENSG00000149658.131969.424701688.948300.221502.232401.45690K562DKC1
YTHDF1ENSG00000149658.131197.21440940.178700.348602.617701.31530K562DNAJC21
YTHDF1ENSG00000149658.131571.094301169.730200.425503.668002.60520K562EFTUD2
YTHDF1ENSG00000149658.131392.786701773.52080-0.348604.402503.52280K562EIF2S2
YTHDF1ENSG00000149658.131330.76320889.323500.581403.267702.16670K562EIF3A
YTHDF1ENSG00000149658.131194.98860798.244700.582008.157606.79810K562EIF3G
YTHDF1ENSG00000149658.131344.079901018.894800.399503.647602.70810K562EIF4A3
YTHDF1ENSG00000149658.131690.847101059.612300.6741013.9928012.73540K562FXR1
YTHDF1ENSG00000149658.131485.445301107.099100.424004.206003.11090K562METAP2
YTHDF1ENSG00000149658.133221.252102580.606700.319802.767101.63740K562MSI2
YTHDF1ENSG00000149658.131334.692601017.390900.391504.106802.59180K562NCBP2
YTHDF1ENSG00000149658.132117.423401783.355400.247604.014903.13420K562NSUN2
YTHDF1ENSG00000149658.131347.16540935.095700.526605.722204.30750K562PCBP2
YTHDF1ENSG00000149658.131702.430701138.286600.580606.166805.04770K562PRPF8
YTHDF1ENSG00000149658.133434.596502641.559100.378704.073203.08990K562PUF60
YTHDF1ENSG00000149658.131824.160901516.667400.266202.700002.11260K562RBM15
YTHDF1ENSG00000149658.131243.53710979.076300.344902.664901.84120K562RBM22
YTHDF1ENSG00000149658.131442.313701142.975400.335502.833901.73870K562SAFB
YTHDF1ENSG00000149658.131134.35750769.006800.560707.181405.76290K562SF3B4
YTHDF1ENSG00000149658.132243.339601218.978700.879904.443902.63280K562SFPQ
YTHDF1ENSG00000149658.131815.542401148.578000.660502.643301.45320K562SNRNP200
YTHDF1ENSG00000149658.131655.698001001.011200.7259012.0505010.57240K562SRSF1
YTHDF1ENSG00000149658.131210.11610949.333900.350102.821101.75560K562SRSF4
YTHDF1ENSG00000149658.131269.386801013.077700.325302.233701.59350K562TARDBP
YTHDF1ENSG00000149658.13910.61220740.384000.298502.250301.52650K562U2AF2
YTHDF1ENSG00000149658.131934.553901682.518700.201302.296201.51890K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for YTHDF1 is not available on ENCORE database.





6 RBPs can affect the splicing of YTHDF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEYTHDF1ENSG00000149658.13chr20-618336386183515961827830618280866184521561845295-0.109000.000000.00017excludedHepG2AKAP1
SEYTHDF1ENSG00000149658.13chr20-618336386183515961827830618280866184521561845295-0.057000.001810.04089excludedHepG2SRSF1
SEYTHDF1ENSG00000149658.13chr20-618336386183515961827830618280866184521561845295-0.088000.000090.01592excludedHepG2SSB
A3SSYTHDF1ENSG00000149658.13chr20-6184521561845405618452156184529561846928618469530.136000.000000.00005longerK562AQR
A5SSYTHDF1ENSG00000149658.13chr20-618467996184695361846928618469536184521561845295-0.132000.001160.07111shorterHepG2HNRNPK
A5SSYTHDF1ENSG00000149658.13chr20-618467996184695361846928618469536184521561845295-0.114000.000170.01940shorterHepG2U2AF1
MXEYTHDF1ENSG00000149658.13chr20-6184521561845295618469286184695361827718618280866184721761847491-0.406000.000110.001302includedK562AQR
MXEYTHDF1ENSG00000149658.13chr20-6184521561845295618469286184695361833638618351596184721761847586-0.063000.011720.071992includedK562AQR
MXEYTHDF1ENSG00000149658.13chr20-6183363861835159618469286184695361826780618280866184721761847586-0.105000.000010.000132includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for YTHDF1 is not avaliable on ENCORE database.