WIPI2

General Information

Gene Name       : WIPI2
Gene ID             : ENSG00000157954.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: WIPI2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WIPI2ENSG00000157954.1423.2929.4026.34ENCSR000AEF
HepG2WIPI2ENSG00000157954.1447.5835.6741.62ENCSR985KAT
K562WIPI2ENSG00000157954.1439.5335.7537.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WIPI2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WIPI2 RNA is bound by 17 proteins.  







eCLIP assay for WIPI2 is not avaliable on ENCORE database.





17 proteins are bound to WIPI2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr752710385271120+3'-UTR3.030873.25603K562TROVE2
chr752710115271063+3'-UTR3.839433.39506K562IGF2BP2
chr752709705270996+3'-UTR5.6423560.15110K562PUM2
chr752704675270626+3'-UTR,CDS3.189255.93591K562FXR2
chr752707015270749+3'-UTR4.4550315.08701K562PABPC4
chr752709255270970+3'-UTR5.8533886.29805K562PUM2
chr752299835230093+5'-UTR,CDS3.540458.31998HepG2DDX3X
chr752540685254142+5'-UTR,CDS,intron-Proximal5.624166.40247K562SF3B4
chr752654085265482+CDS,intron-Proximal6.1739212.80845K562SF3B4
chr752561935256228+CDS,intron-Proximal3.712024.14015K562DDX24
chr752543255254387+CDS,intron-Proximal4.667364.13847K562AQR
chr752653815265488+CDS,intron-Proximal5.181488.74981HepG2SF3B4
chr752391935239242+CDS,intron-Proximal3.750394.21358HepG2U2AF2
chr752677335267792+CDS,intron-Proximal3.506975.30777HepG2PPIG
chr752667985266856+CDS,intron-Proximal3.569823.62357HepG2U2AF2
chr752622305262265+CDS,intron-Proximal5.6899927.25959K562U2AF1
chr752622195262267+CDS,intron-Proximal4.8393130.79288K562U2AF2
chr752667845266853+CDS,intron-Proximal4.5742319.15895K562SF3B4
chr752567355256801+CDS3.252396.56666K562YBX3
chr752622195262264+CDS,intron-Proximal4.292035.33616HepG2U2AF1
chr752562285256291+CDS,intron-Proximal4.285807.99930K562DDX24
chr752668555266976+CDS,intron-Proximal3.137397.41174K562YBX3
chr752622445262308+CDS,intron-Proximal3.541285.77496K562DDX24
chr752622195262275+CDS,intron-Proximal4.7842517.19157HepG2U2AF2
chr752633665263453+intron-Distal4.531395.62822K562HNRNPK
chr752631605263325+intron-Distal4.148627.57201K562HNRNPK
chr752633645263436+intron-Distal3.492294.16645HepG2HNRNPK
chr752636555263757+intron-Distal3.184165.16765K562HNRNPK
chr752632655263306+intron-Distal4.715193.11886K562DROSHA
chr752480795248130+intron-Distal3.861873.04224HepG2SUGP2
chr752695715269623+intron-Distal3.709283.21162HepG2HNRNPC
chr752656025265662+intron-Distal,intron-Proximal3.664183.19080K562U2AF2
chr752667555266784+intron-Proximal4.3050113.70474K562SF3B4
chr752622195262230+intron-Proximal6.5848725.25822K562U2AF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WIPI2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WIPI2 is not available on ENCORE database.

  • 69 RBPs can affect the levels of WIPI2.  








The Knockdown/knockout RNA-Seq assay for WIPI2 is not available on ENCORE database.





69 RBPs can affect the gene expression of WIPI2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WIPI2ENSG00000157954.101166.85480820.256000.508404.909804.14200HepG2BOP1
WIPI2ENSG00000157954.101008.755901261.53960-0.322604.268203.47630HepG2CKAP4
WIPI2ENSG00000157954.10775.31880964.78030-0.315402.097401.49770HepG2DDX21
WIPI2ENSG00000157954.10914.521801141.64130-0.320002.562501.44080HepG2EIF2S2
WIPI2ENSG00000157954.101106.396301397.14860-0.336603.608502.67340HepG2EIF4G1
WIPI2ENSG00000157954.102584.034302029.103900.348703.989103.28970HepG2ETF1
WIPI2ENSG00000157954.101518.307901233.025900.300202.177101.43690HepG2EWSR1
WIPI2ENSG00000157954.10969.963901207.55850-0.316102.371201.64110HepG2FUBP3
WIPI2ENSG00000157954.10527.38860766.85660-0.540104.281203.15550HepG2GEMIN5
WIPI2ENSG00000157954.101641.625501301.052200.335304.567403.67290HepG2HNRNPF
WIPI2ENSG00000157954.10841.083701048.48660-0.318002.452201.55580HepG2HNRNPM
WIPI2ENSG00000157954.101782.019001281.169200.476006.317205.26680HepG2IGF2BP1
WIPI2ENSG00000157954.101264.060401572.63700-0.315102.045501.45580HepG2IGF2BP2
WIPI2ENSG00000157954.10727.79060946.56960-0.379204.859403.91050HepG2ILF2
WIPI2ENSG00000157954.101095.535301677.86500-0.615005.628404.75380HepG2MATR3
WIPI2ENSG00000157954.10984.465301229.85760-0.321102.638101.84830HepG2MSI2
WIPI2ENSG00000157954.101359.232501717.36000-0.337402.190901.62520HepG2NCBP2
WIPI2ENSG00000157954.101147.836801404.16730-0.290802.526101.79880HepG2NOL12
WIPI2ENSG00000157954.101180.390701529.29220-0.373602.605301.90230HepG2PABPC4
WIPI2ENSG00000157954.101050.464801573.79850-0.5832011.3983010.30290HepG2PCBP1
WIPI2ENSG00000157954.101038.07600826.521900.328703.117402.33900HepG2PPIL4
WIPI2ENSG00000157954.101149.272401601.43210-0.478608.318207.47480HepG2PTBP1
WIPI2ENSG00000157954.101113.172401285.32020-0.207501.992301.45080HepG2PUS1
WIPI2ENSG00000157954.101466.634401734.31950-0.241902.081701.52850HepG2QKI
WIPI2ENSG00000157954.101533.750301782.21250-0.216602.069801.58740HepG2NELFE
WIPI2ENSG00000157954.102070.085701401.489100.562607.323506.29140HepG2RPLP0
WIPI2ENSG00000157954.10983.29860825.252800.252702.341001.74040HepG2SAFB2
WIPI2ENSG00000157954.10609.21420841.10900-0.465303.657102.57080HepG2SERBP1
WIPI2ENSG00000157954.101177.66060806.359400.546305.450204.48550HepG2SF3B1
WIPI2ENSG00000157954.101421.697401667.23780-0.229802.270001.72760HepG2SF3B4
WIPI2ENSG00000157954.101628.409601915.50030-0.234302.863302.35590HepG2SRFBP1
WIPI2ENSG00000157954.101167.026301740.25970-0.5765011.8047010.97340HepG2SRSF1
WIPI2ENSG00000157954.101742.023801278.226300.446507.681406.61720HepG2SRSF7
WIPI2ENSG00000157954.101202.756001415.81500-0.235302.450801.92420HepG2SRSF9
WIPI2ENSG00000157954.101316.224601663.08760-0.337504.834004.19270HepG2SSB
WIPI2ENSG00000157954.101242.352201505.18660-0.276903.261302.59720HepG2SUCLG1
WIPI2ENSG00000157954.10766.902701026.09710-0.420103.759502.67680HepG2SUPT6H
WIPI2ENSG00000157954.101334.359801564.28090-0.229401.875201.39700HepG2TAF15
WIPI2ENSG00000157954.101107.390301437.28930-0.376203.726502.76310HepG2TIA1
WIPI2ENSG00000157954.10992.693501318.28620-0.409205.771304.95850HepG2UTP3
WIPI2ENSG00000157954.10695.33400980.58810-0.495902.624101.40120HepG2XRCC5
WIPI2ENSG00000157954.10764.636201096.35510-0.519903.086501.96530HepG2XRCC6
WIPI2ENSG00000157954.101243.612201501.73140-0.272103.696903.08950HepG2ZNF622
WIPI2ENSG00000157954.102600.606701860.285800.4832010.769909.74370K562AGGF1
WIPI2ENSG00000157954.102865.437702044.261200.487106.305004.67100K562AKAP8
WIPI2ENSG00000157954.102617.252001935.733400.435105.086204.18930K562AKAP8L
WIPI2ENSG00000157954.103155.922801880.890100.7465012.6512011.52850K562AQR
WIPI2ENSG00000157954.101309.794301067.387800.295202.477801.49500K562DDX3X
WIPI2ENSG00000157954.101178.51120873.236800.432403.298302.29670K562EFTUD2
WIPI2ENSG00000157954.101354.486401115.202200.280302.084701.36740K562EIF4A3
WIPI2ENSG00000157954.101630.574001070.954800.606407.620406.14550K562FIP1L1
WIPI2ENSG00000157954.10491.82850791.10680-0.685704.972103.95950K562G3BP2
WIPI2ENSG00000157954.10920.95180740.518600.314502.066001.37610K562GPKOW
WIPI2ENSG00000157954.102480.974802054.220800.272202.908302.06020K562KIF1C
WIPI2ENSG00000157954.102517.984901966.456600.356603.482002.23170K562MAK16
WIPI2ENSG00000157954.10910.22410722.847900.332402.350301.54660K562METAP2
WIPI2ENSG00000157954.102147.655301613.021000.412902.715101.84130K562NAA15
WIPI2ENSG00000157954.101798.648001593.815400.174302.065801.41000K562NSUN2
WIPI2ENSG00000157954.101977.258501257.380300.653002.975901.93870K562PABPN1
WIPI2ENSG00000157954.101539.457701215.893900.340302.151901.43310K562PPIG
WIPI2ENSG00000157954.101088.25090849.765000.356802.269901.58710K562PRPF8
WIPI2ENSG00000157954.103390.794702595.009400.385804.105003.11780K562PUF60
WIPI2ENSG00000157954.103064.565001919.561100.6748010.346409.34200K562PUS1
WIPI2ENSG00000157954.102725.730101870.451800.5432010.598109.46220K562RBM15
WIPI2ENSG00000157954.101301.566101035.459100.329902.501201.70530K562RBM22
WIPI2ENSG00000157954.101073.21540822.453500.383803.686802.69520K562SF3B4
WIPI2ENSG00000157954.101905.110901611.328000.241503.157302.16260K562SRPK2
WIPI2ENSG00000157954.101443.283101058.931600.446604.830403.90110K562SRSF1
WIPI2ENSG00000157954.101151.692301371.17100-0.251701.999801.30220K562SYNCRIP
WIPI2ENSG00000157954.101363.677901071.597300.347601.898801.30480K562TARDBP
WIPI2ENSG00000157954.101339.236401033.705700.373502.996202.13900K562TIA1
WIPI2ENSG00000157954.101271.027601014.634300.324902.322101.34000K562TRA2A
WIPI2ENSG00000157954.101925.031201689.959800.187801.942201.33260K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WIPI2 is not available on ENCORE database.





9 RBPs can affect the splicing of WIPI2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWIPI2ENSG00000157954.10chr7+5232748523280252298185230124523920652392890.232000.000790.03136includedK562PRPF8
SEWIPI2ENSG00000157954.10chr7+523274852329765229889523012452392065239289-0.209000.000170.04647excludedHepG2DKC1
SEWIPI2ENSG00000157954.10chr7+523274852328025229818523012452392065239289-0.233000.000150.01382excludedHepG2AKAP1
SEWIPI2ENSG00000157954.10chr7+523917652392895229826523012452541655254335-0.063000.011280.08936excludedK562AQR
SEWIPI2ENSG00000157954.10chr7+5232748523280252298765230124523920652392890.419000.000050.00473includedHepG2SFPQ
SEWIPI2ENSG00000157954.10chr7+523274852328025229818523012452392065239289-0.429000.000000.00000excludedK562HNRNPU
SEWIPI2ENSG00000157954.10chr7+523920652392895229903523012452541655254335-0.080000.003060.06463excludedK562AGGF1
SEWIPI2ENSG00000157954.10chr7+523274852328025229818523012452392065239289-0.295000.001350.05422excludedHepG2HNRNPU
SEWIPI2ENSG00000157954.10chr7+5232748523280252298185230124523920652392890.281000.007250.09201includedK562HNRNPC
A3SSWIPI2ENSG00000157954.10chr7+5256681525681852567205256818525619352562900.084000.000000.00000longerK562AQR
A5SSWIPI2ENSG00000157954.10chr7+5265453526563352654535265561526681052669750.056000.000290.00650longerK562AQR
A5SSWIPI2ENSG00000157954.10chr7+5269238526939652692385269336527046552711010.202000.000280.05991longerK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WIPI2 is not avaliable on ENCORE database.