WDR66

General Information

Gene Name       : WDR66
Gene ID             : ENSG00000158023.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: WDR66)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WDR66ENSG00000158023.90.760.490.62ENCSR000AEF
HepG2WDR66ENSG00000158023.90.030.150.09ENCSR985KAT
K562WDR66ENSG00000158023.911.9312.1712.05ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WDR66 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WDR66 RNA is bound by 4 proteins.  







eCLIP assay for WDR66 is not avaliable on ENCORE database.





4 proteins are bound to WDR66 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12122395148122395278+CDS,intron-Distal,intron-Proximal3.431034.98593K562KHSRP
chr12122400043122400102+CDS,intron-Proximal3.458623.88924K562PRPF8
chr12122380531122380638+CDS,intron-Proximal3.311766.89918K562PRPF8
chr12122402016122402124+intron-Distal4.546346.58261K562KHSRP
chr12122404168122404236+intron-Distal4.159614.05367K562ILF3
chr12122372063122372151+intron-Proximal4.569208.54916K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WDR66 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WDR66 is not available on ENCORE database.

  • 69 RBPs can affect the levels of WDR66.  








The Knockdown/knockout RNA-Seq assay for WDR66 is not available on ENCORE database.





69 RBPs can affect the gene expression of WDR66 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WDR66ENSG00000158023.533.2576013.607701.289202.044001.50680HepG2ACO1
WDR66ENSG00000158023.562.345109.290702.746307.332306.09290HepG2CNOT7
WDR66ENSG00000158023.555.2185010.986402.329303.602402.83660HepG2DDX21
WDR66ENSG00000158023.522.335706.196501.849701.963101.45400HepG2EIF2S1
WDR66ENSG00000158023.577.049406.847103.4921012.7199011.37640HepG2EIF4A3
WDR66ENSG00000158023.542.561106.668002.674104.789403.89950HepG2EIF4B
WDR66ENSG00000158023.576.4739023.972901.673505.820305.00190HepG2ETF1
WDR66ENSG00000158023.550.9548013.298401.937902.600301.79120HepG2EWSR1
WDR66ENSG00000158023.556.2137017.643501.671702.741301.97600HepG2FIP1L1
WDR66ENSG00000158023.566.058106.409503.3654011.114009.82410HepG2G3BP1
WDR66ENSG00000158023.543.2530013.377901.692803.179102.08600HepG2GNB2L1
WDR66ENSG00000158023.549.6755020.215501.297002.386801.78840HepG2GPKOW
WDR66ENSG00000158023.527.556506.514702.080502.835202.15340HepG2IGF2BP2
WDR66ENSG00000158023.591.8085033.748801.443704.510203.43920HepG2LARP4
WDR66ENSG00000158023.569.605906.913003.3317010.746909.47860HepG2MAGOH
WDR66ENSG00000158023.525.868706.951301.895702.149901.58960HepG2MATR3
WDR66ENSG00000158023.539.482308.480802.218804.134503.03310HepG2PABPC1
WDR66ENSG00000158023.559.1933011.631402.347305.538804.43820HepG2PRPF8
WDR66ENSG00000158023.525.587605.217702.293903.017602.45110HepG2PTBP1
WDR66ENSG00000158023.546.6568022.524801.050502.017001.49650HepG2PUF60
WDR66ENSG00000158023.541.1220011.794101.801702.891502.17300HepG2RAVER1
WDR66ENSG00000158023.5111.3143020.037702.473805.232104.57590HepG2RBM22
WDR66ENSG00000158023.541.344605.808502.831405.333604.62200HepG2NELFE
WDR66ENSG00000158023.541.007506.904402.570205.140604.33320HepG2RPS19
WDR66ENSG00000158023.548.6834014.575301.739803.442202.54980HepG2RPS2
WDR66ENSG00000158023.547.9478016.261601.559903.166502.44460HepG2SF3A3
WDR66ENSG00000158023.533.848105.435902.638403.785303.11100HepG2SF3B4
WDR66ENSG00000158023.541.3639018.465101.163502.070901.50220HepG2SMN1
WDR66ENSG00000158023.5135.0158022.633302.5765016.5218015.56750HepG2SRFBP1
WDR66ENSG00000158023.574.173405.672503.7088010.140809.36200HepG2SRSF1
WDR66ENSG00000158023.539.917104.613603.112907.170706.35640HepG2SRSF9
WDR66ENSG00000158023.543.1808019.653601.135502.204901.73430HepG2SSB
WDR66ENSG00000158023.5247.8484015.017504.0446031.4357029.61910HepG2SUPV3L1
WDR66ENSG00000158023.545.8299017.274701.407502.931002.41910HepG2TIAL1
WDR66ENSG00000158023.556.4873015.087101.904503.924103.18110HepG2U2AF1
WDR66ENSG00000158023.562.1959011.557002.427904.114302.89960HepG2U2AF2
WDR66ENSG00000158023.539.3893012.976101.601802.967101.86800HepG2XRCC6
WDR66ENSG00000158023.590.7424010.817803.0683014.5100013.16680HepG2ZC3H8
WDR66ENSG00000158023.5409.29600654.44900-0.677108.114007.21190K562AGGF1
WDR66ENSG00000158023.5549.45970719.10030-0.388202.774701.79080K562AKAP8
WDR66ENSG00000158023.5462.03330680.97390-0.559604.792803.92560K562AKAP8L
WDR66ENSG00000158023.5560.96790714.48690-0.349002.842701.91810K562ATP5C1
WDR66ENSG00000158023.5926.02380472.674700.9701012.1520010.27960K562BOP1
WDR66ENSG00000158023.5617.05300454.997000.439403.411801.71780K562CEBPZ
WDR66ENSG00000158023.51212.45910653.420800.891806.373104.70610K562CNOT7
WDR66ENSG00000158023.5523.62390674.17960-0.364602.694101.60270K562CPEB4
WDR66ENSG00000158023.5787.33560502.611200.647406.955505.70450K562CPSF6
WDR66ENSG00000158023.5466.00680732.83870-0.653108.272306.60910K562DKC1
WDR66ENSG00000158023.5333.80200229.902600.537902.787401.43740K562DNAJC21
WDR66ENSG00000158023.5487.88550342.263900.511302.542101.32180K562EEF2
WDR66ENSG00000158023.5609.06930453.300300.426003.700402.89000K562EIF2S2
WDR66ENSG00000158023.5870.02490511.351700.766608.299906.77120K562FMR1
WDR66ENSG00000158023.5720.58230433.397900.733406.472705.01790K562FTO
WDR66ENSG00000158023.5610.32150479.887900.346802.014701.33400K562GPKOW
WDR66ENSG00000158023.5953.36290611.578900.640403.762601.90950K562HNRNPAB
WDR66ENSG00000158023.5599.36880350.597300.773507.603806.66050K562HNRNPC
WDR66ENSG00000158023.5295.97070449.86730-0.604005.055103.83450K562HNRNPU
WDR66ENSG00000158023.5285.53780434.40310-0.605404.555102.94210K562IGF2BP3
WDR66ENSG00000158023.5516.44200691.79100-0.421702.739301.67040K562MAK16
WDR66ENSG00000158023.5519.86200809.62210-0.639107.275805.66630K562MBNL1
WDR66ENSG00000158023.5607.27410468.416600.374502.341501.53880K562METAP2
WDR66ENSG00000158023.5663.75050488.779100.441404.258303.27400K562MTPAP
WDR66ENSG00000158023.5383.70030567.48340-0.564603.070702.13380K562NAA15
WDR66ENSG00000158023.5819.98930543.076800.594308.994007.75300K562NSUN2
WDR66ENSG00000158023.51248.60920627.748200.992008.541006.38510K562PABPC1
WDR66ENSG00000158023.51115.04660935.008400.254002.171301.31980K562PUM2
WDR66ENSG00000158023.5527.73360675.41000-0.356002.070501.58820K562PUS1
WDR66ENSG00000158023.5467.70180658.02670-0.492604.442203.70950K562RBM15
WDR66ENSG00000158023.5323.68260440.12960-0.443302.481201.45470K562NELFE
WDR66ENSG00000158023.5760.21560535.879200.504405.420204.30770K562SF3A3
WDR66ENSG00000158023.5291.30520394.40420-0.437102.674601.83500K562SF3B4
WDR66ENSG00000158023.5550.10200427.544100.363502.281701.63230K562SRSF1
WDR66ENSG00000158023.5502.92270311.458600.691204.630903.29000K562SUPV3L1
WDR66ENSG00000158023.5305.82330432.72550-0.500803.033402.29200K562TARDBP
WDR66ENSG00000158023.5467.86420329.682000.504902.833401.80000K562UCHL5
WDR66ENSG00000158023.5887.26120575.835900.623609.264108.04360K562UPF1
WDR66ENSG00000158023.5750.27850492.724500.606506.256204.90930K562WDR3
WDR66ENSG00000158023.5898.00480706.592100.345702.425301.62570K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WDR66 is not available on ENCORE database.





3 RBPs can affect the splicing of WDR66 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXEWDR66ENSG00000158023.5chr12+122386889122386967122389385122389436122380800122380881122392025122392240-0.127000.000380.074572includedK562METAP2
MXEWDR66ENSG00000158023.5chr12+1223868891223869671223893851223894361223808001223808811223920251223922400.200000.000100.019701includedK562ZNF800
MXEWDR66ENSG00000158023.5chr12+122386889122386967122389385122389436122380800122380881122392025122392240-0.135000.000080.015312includedK562CPSF6

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WDR66 is not avaliable on ENCORE database.