UBR2

General Information

Gene Name : UBR2
Gene ID : ENSG00000024048.10
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: UBR2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	UBR2	ENSG00000024048.10	8.90	7.23	8.07	ENCSR000AEF
HepG2	UBR2	ENSG00000024048.10	9.21	14.43	11.82	ENCSR985KAT
K562	UBR2	ENSG00000024048.10	12.42	14.42	13.42	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
UBR2	Ribo-STAMP-293T	shRNA			BGRSLV05-35,BGRSLV05-36	BGRSLV05-1,BGRSLV05-2		NotSatisfied	ENCORE2
UBR2	Ribo-STAMP-293T	shRNA			BGRSLV07-29,BGRSLV07-30	BGRSLV07-1,BGRSLV07-2		NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for UBR2 is not avaliable on ENCORE database.

Proteins bound to RNA

UBR2 RNA is bound by 30 proteins.

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eCLIP assay for UBR2 is not avaliable on ENCORE database.

30 proteins are bound to UBR2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr6	42610601	42610661	+	intron-Distal	6.98962	34.16128	HepG2	QKI
chr6	42610559	42610652	+	intron-Distal	4.95080	27.88496	K562	QKI
chr6	42603157	42603238	+	CDS	6.37847	25.64815	K562	LIN28B
chr6	42609362	42609422	+	CDS	4.29107	18.05569	HepG2	BCLAF1
chr6	42610552	42610601	+	intron-Distal	6.26306	17.92967	HepG2	QKI
chr6	42641877	42641973	+	3'-UTR,CDS,intron-Proximal	5.98189	17.45859	HepG2	PRPF8
chr6	42543719	42543807	+	intron-Distal	5.87234	14.38018	HepG2	PTBP1
chr6	42639355	42639432	+	intron-Distal	6.02959	14.07413	K562	PTBP1
chr6	42613210	42613250	+	CDS	6.10565	13.95734	HepG2	BCLAF1
chr6	42623383	42623455	+	CDS	3.59902	13.90271	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 166 entries

eCLIP assay for UBR2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for UBR2 is not available on ENCORE database.
58 RBPs can affect the levels of UBR2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for UBR2 is not available on ENCORE database.

58 RBPs can affect the gene expression of UBR2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
UBR2	ENSG00000024048.6	2452.42930	1656.68280	0.56580	13.65820	12.77920	HepG2	SRSF1
UBR2	ENSG00000024048.6	2388.96940	1498.44600	0.67280	11.35670	10.04980	HepG2	RBM25
UBR2	ENSG00000024048.6	1724.65820	2508.24390	-0.54040	10.89530	9.78070	K562	FXR1
UBR2	ENSG00000024048.6	1799.86380	2770.23510	-0.62210	9.69790	8.25870	K562	GRSF1
UBR2	ENSG00000024048.6	2769.79980	2065.62070	0.42310	9.08070	8.25620	HepG2	SSB
UBR2	ENSG00000024048.6	1723.45590	1255.89620	0.45650	9.03440	7.93900	HepG2	ZC3H8
UBR2	ENSG00000024048.6	1738.35660	2766.63980	-0.67040	9.25650	7.85680	K562	TARDBP
UBR2	ENSG00000024048.6	1022.59750	1385.98160	-0.43870	8.28130	7.07840	HepG2	ILF2
UBR2	ENSG00000024048.6	1208.08510	1654.97150	-0.45410	7.71370	6.79420	HepG2	UTP3
UBR2	ENSG00000024048.6	956.17580	1330.20660	-0.47630	7.61920	6.76040	HepG2	TRIM56
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 65 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for UBR2 is not available on ENCORE database.

15 RBPs can affect the splicing of UBR2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	UBR2	ENSG00000024048.6	chr6	+	42559888	42559967			42541471	42541731	42571325	42571456	-0.69800	0.00000	0.00000	excluded	HepG2	U2AF2
SE	UBR2	ENSG00000024048.6	chr6	+	42601985	42602032			42600542	42600642	42603155	42603284	0.29900	0.00000	0.00263	included	HepG2	FUS
SE	UBR2	ENSG00000024048.6	chr6	+	42612210	42612274			42611951	42612074	42613203	42613328	-0.17400	0.00001	0.00041	excluded	K562	U2AF2
MXE	UBR2	ENSG00000024048.6	chr6	+	42584977	42585076	42585146	42585245	42583739	42583828	42600289	42600453	0.29300	0.00005	0.00738	1included	HepG2	SRSF7
SE	UBR2	ENSG00000024048.6	chr6	+	42612210	42612274			42611951	42612074	42613203	42613328	-0.16000	0.00008	0.00260	excluded	K562	U2AF1
MXE	UBR2	ENSG00000024048.6	chr6	+	42584977	42585076	42585146	42585245	42583739	42583828	42600289	42600453	0.25800	0.00008	0.00475	1included	HepG2	SF3B4
MXE	UBR2	ENSG00000024048.6	chr6	+	42604730	42604932	42607914	42608008	42603155	42603284	42609319	42609430	0.13400	0.00012	0.00145	1included	K562	AQR
A3SS	UBR2	ENSG00000024048.6	chr6	+	42633882	42633983			42633904	42633983	42633146	42633250	0.10800	0.00014	0.00117	longer	K562	AQR
A3SS	UBR2	ENSG00000024048.6	chr6	+	42646245	42646407			42646276	42646407	42644520	42644611	0.07900	0.00036	0.00281	longer	K562	AQR
SE	UBR2	ENSG00000024048.6	chr6	+	42601985	42602032			42600542	42600642	42603155	42603284	0.06400	0.00064	0.09106	included	K562	EIF4G2

Showing 1 to 10 of 38 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

UBR2

General Information

Functions

Localization

Domains (AlphaFold: UBR2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for UBR2 is not avaliable on ENCORE database.

30 proteins are bound to UBR2 RNA:

eCLIP assay for UBR2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for UBR2 is not available on ENCORE database.

58 RBPs can affect the gene expression of UBR2 :

The Knockdown/knockout RNA-Seq assay for UBR2 is not available on ENCORE database.

15 RBPs can affect the splicing of UBR2 :

The Knockdown/knockout RNA-Seq assay for UBR2 is not avaliable on ENCORE database.