TXN2

General Information

Gene Name       : TXN2
Gene ID             : ENSG00000100348.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TXN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TXN2ENSG00000100348.964.6868.4266.55ENCSR000AEF
HepG2TXN2ENSG00000100348.9122.5368.4795.50ENCSR985KAT
K562TXN2ENSG00000100348.989.9672.8581.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TXN2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TXN2 RNA is bound by 15 proteins.  







eCLIP assay for TXN2 is not avaliable on ENCORE database.





15 proteins are bound to TXN2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr223686317736863232-3'-UTR,intron-Distal6.7106225.48379K562UPF1
chr223686364336863816-3'-UTR,intron-Distal6.7628224.73084HepG2UPF1
chr223686347836863612-3'-UTR,intron-Distal,intron-Proximal5.0037715.10113HepG2UPF1
chr223686325536863306-3'-UTR,intron-Distal4.904667.10674HepG2UPF1
chr223686319936863241-3'-UTR,intron-Distal6.0747310.19274K562PABPC4
chr223686374236863902-3'-UTR,CDS,intron-Distal,intron-Proximal3.737299.11529HepG2LARP4
chr223686330636863360-3'-UTR,intron-Distal3.904666.19596HepG2UPF1
chr223686329836863365-3'-UTR,intron-Distal3.041904.88619HepG2LARP4
chr223686328136863371-3'-UTR,intron-Distal3.457645.56056K562AKAP1
chr223686324136863369-3'-UTR,intron-Distal4.123604.19401K562HNRNPK
chr223686346336863489-3'-UTR,intron-Distal3.722196.67761K562UPF1
chr223686312436863177-3'-UTR,intron-Distal6.0679215.26585K562UPF1
chr223686329436863377-3'-UTR,intron-Distal4.4678441.80195K562UPF1
chr223686354036863611-3'-UTR,intron-Distal,intron-Proximal4.4969119.04148K562UPF1
chr223686341936863476-3'-UTR,intron-Distal4.7165513.81544K562PUM2
chr223686323236863294-3'-UTR,intron-Distal5.8185135.44652K562UPF1
chr223686325836863313-3'-UTR,intron-Distal4.300273.94601K562PCBP1
chr223686324036863351-3'-UTR,intron-Distal5.6372812.91326HepG2AKAP1
chr223686372236863768-3'-UTR,intron-Distal3.403906.00918K562FAM120A
chr223686325236863367-3'-UTR,intron-Distal3.5565129.91869K562PABPC4
chr223686341436863501-3'-UTR,intron-Distal,intron-Proximal3.4614110.49480K562FAM120A
chr223686355336863637-3'-UTR,intron-Distal,intron-Proximal3.731385.13191K562AKAP1
chr223686354536863665-3'-UTR,intron-Distal,intron-Proximal4.1015316.81273K562PCBP1
chr223686319636863293-3'-UTR,intron-Distal3.518324.32261K562IGF2BP2
chr223686324036863291-3'-UTR,intron-Distal4.1008414.09124K562FAM120A
chr223686352436863653-3'-UTR,intron-Distal,intron-Proximal4.9397914.27070HepG2AKAP1
chr223686329136863369-3'-UTR,intron-Distal5.2851924.29488K562FAM120A
chr223686362636863694-3'-UTR,intron-Distal,intron-Proximal4.8665417.94406K562UPF1
chr223686367336863805-3'-UTR,intron-Distal4.3660110.99736HepG2AKAP1
chr223687675336876776-5'-UTR,CDS,intron-Distal3.6187811.95636K562YBX3
chr223687677636876801-5'-UTR,CDS,intron-Distal,intron-Proximal3.9491117.76645K562YBX3
chr223687278036872877-5'-UTR,CDS,intron-Distal3.000224.32857K562LIN28B
chr223687668836876699-5'-UTR,CDS,intron-Distal3.4383210.89350K562YBX3
chr223687761436877663-5'-UTR,intron-Distal,intron-Proximal5.105273.85934HepG2DDX3X
chr223687679636876886-5'-UTR,CDS,intron-Distal,intron-Proximal3.5577715.59007K562DDX3X
chr223687662636876693-5'-UTR,CDS,intron-Distal4.369844.16554HepG2PPIG
chr223687760936877621-5'-UTR,intron-Distal3.633613.33524K562DDX3X
chr223687665536876688-5'-UTR,CDS,intron-Distal3.8634318.40518K562YBX3
chr223687681236876850-5'-UTR,CDS,intron-Distal,intron-Proximal4.9776855.58006K562YBX3
chr223687755136877612-5'-UTR,intron-Distal4.559497.50107K562AQR
chr223687680136876812-5'-UTR,CDS,intron-Distal,intron-Proximal6.0032978.06305K562YBX3
chr223687693636877009-intron-Distal,intron-Proximal3.828394.77518HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TXN2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TXN2 is not available on ENCORE database.

  • 73 RBPs can affect the levels of TXN2.  








The Knockdown/knockout RNA-Seq assay for TXN2 is not available on ENCORE database.





73 RBPs can affect the gene expression of TXN2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TXN2ENSG00000100348.52222.939101608.273600.466903.869102.76750HepG2ABCF1
TXN2ENSG00000100348.52720.361901922.346300.500804.112803.48170HepG2AKAP1
TXN2ENSG00000100348.51368.747901019.784500.424502.371801.50620HepG2BCCIP
TXN2ENSG00000100348.51216.73460740.880600.715604.679903.68070HepG2CNOT7
TXN2ENSG00000100348.51200.59420983.714400.287303.420802.50470HepG2DDX19B
TXN2ENSG00000100348.51497.997501841.31370-0.297701.895001.36740HepG2DDX3X
TXN2ENSG00000100348.51367.719801002.704900.447802.662901.90110HepG2DDX55
TXN2ENSG00000100348.51119.526301520.54120-0.441703.449902.79150HepG2EIF2S1
TXN2ENSG00000100348.5998.530701636.23980-0.712505.832504.85830HepG2EIF4B
TXN2ENSG00000100348.51508.851901783.51330-0.241302.845502.23740HepG2ETF1
TXN2ENSG00000100348.51263.205301039.404600.281202.102001.37530HepG2EWSR1
TXN2ENSG00000100348.5527.96510834.54770-0.660605.399903.67170HepG2FKBP4
TXN2ENSG00000100348.5760.977701250.80560-0.716902.831201.80400HepG2FTO
TXN2ENSG00000100348.51069.434601670.08540-0.643107.201605.75150HepG2G3BP2
TXN2ENSG00000100348.51593.076901358.264700.230002.531001.63210HepG2HNRNPA2B1
TXN2ENSG00000100348.51265.762501000.916200.338602.556301.88790HepG2HNRNPC
TXN2ENSG00000100348.51105.654101593.23380-0.527105.432204.47810HepG2HNRNPK
TXN2ENSG00000100348.51643.798601346.075200.288204.638703.78270HepG2HNRNPL
TXN2ENSG00000100348.51275.93580994.297600.359704.696103.92350HepG2HNRNPU
TXN2ENSG00000100348.51283.456501598.62840-0.316802.077401.48360HepG2IGF2BP2
TXN2ENSG00000100348.52340.315701839.939100.346902.024101.32210HepG2LARP4
TXN2ENSG00000100348.51088.969401696.36300-0.639506.754005.74280HepG2MAGOH
TXN2ENSG00000100348.51073.504701314.17290-0.291802.279301.54230HepG2MSI2
TXN2ENSG00000100348.51206.887401745.88790-0.532704.773403.95490HepG2NCBP2
TXN2ENSG00000100348.51075.478601554.51810-0.531504.751903.81770HepG2PABPC4
TXN2ENSG00000100348.5914.632501530.46980-0.7427017.6463016.32560HepG2PCBP1
TXN2ENSG00000100348.5890.30130711.446800.323402.512701.34500HepG2PKM
TXN2ENSG00000100348.5733.574701187.42490-0.6948013.0922011.59810HepG2PRPF4
TXN2ENSG00000100348.51171.502901557.27650-0.410705.955705.21490HepG2PTBP1
TXN2ENSG00000100348.51733.087401398.919200.308902.866102.26050HepG2PUF60
TXN2ENSG00000100348.51675.292201485.101900.173802.090901.56090HepG2PUM1
TXN2ENSG00000100348.51074.765801483.96280-0.465405.250804.34080HepG2PUM2
TXN2ENSG00000100348.51223.946601686.64080-0.462606.348405.45730HepG2QKI
TXN2ENSG00000100348.51155.364701530.70780-0.405904.204903.38880HepG2RBM25
TXN2ENSG00000100348.51252.365801733.12730-0.468707.924807.09300HepG2NELFE
TXN2ENSG00000100348.51160.102501614.12170-0.476508.085207.11460HepG2RECQL
TXN2ENSG00000100348.51081.75760837.143800.369702.945402.31490HepG2RPS19
TXN2ENSG00000100348.5533.60840764.89650-0.519503.662202.77530HepG2RRP9
TXN2ENSG00000100348.51214.99850885.457100.456407.227106.25730HepG2SAFB2
TXN2ENSG00000100348.51067.54340840.137100.345502.230301.38270HepG2SERBP1
TXN2ENSG00000100348.51927.571401311.214900.555804.348103.49300HepG2SF3A3
TXN2ENSG00000100348.51334.243701621.38640-0.281203.340002.69780HepG2SF3B4
TXN2ENSG00000100348.51284.690501032.577500.315104.355203.58040HepG2SMN1
TXN2ENSG00000100348.51129.166901381.33370-0.290802.832902.19970HepG2SRSF5
TXN2ENSG00000100348.51052.436801376.79690-0.387605.683704.94230HepG2SRSF9
TXN2ENSG00000100348.51047.882701521.08310-0.537608.531307.63540HepG2TAF15
TXN2ENSG00000100348.51162.177201397.74090-0.266302.124101.39010HepG2TIA1
TXN2ENSG00000100348.51555.14620966.089000.6867011.9619011.05040HepG2TIAL1
TXN2ENSG00000100348.51133.89160974.786200.218001.924601.43760HepG2TRIM56
TXN2ENSG00000100348.51799.587901389.096200.373402.860902.22250HepG2U2AF1
TXN2ENSG00000100348.51417.134401162.846500.285203.325102.57130HepG2UPF1
TXN2ENSG00000100348.51425.720301122.683600.344604.448203.71770HepG2UTP3
TXN2ENSG00000100348.51280.10940982.529600.381602.240501.58230HepG2XRN2
TXN2ENSG00000100348.5752.821901171.86040-0.6384012.8866011.61170HepG2ZC3H8
TXN2ENSG00000100348.51550.839601278.909500.278003.905703.28600HepG2ZNF622
TXN2ENSG00000100348.51408.628301910.03530-0.439304.709203.12540K562AARS
TXN2ENSG00000100348.51388.993901671.00060-0.266702.929701.56560K562DDX27
TXN2ENSG00000100348.52451.702103110.86090-0.343505.709104.82320K562DDX47
TXN2ENSG00000100348.51059.499601595.74610-0.590803.485702.34480K562EIF3A
TXN2ENSG00000100348.51209.830201555.87920-0.362902.367101.41870K562EIF3D
TXN2ENSG00000100348.53728.978102182.756500.7725013.8761011.82170K562FIP1L1
TXN2ENSG00000100348.51312.272801814.92010-0.467804.089702.68480K562FKBP4
TXN2ENSG00000100348.51660.105002015.34700-0.279802.068001.32410K562FMR1
TXN2ENSG00000100348.51299.109101708.15790-0.394902.989502.03710K562FTO
TXN2ENSG00000100348.5349.47280978.34680-1.4852019.9709017.60580K562G3BP2
TXN2ENSG00000100348.52645.357801795.340200.559105.585004.20200K562HNRNPM
TXN2ENSG00000100348.52087.021402519.80430-0.271903.035102.10220K562HNRNPU
TXN2ENSG00000100348.53659.962802959.365900.306402.625501.84930K562HSPD1
TXN2ENSG00000100348.51746.503401387.257700.332103.110202.12820K562MATR3
TXN2ENSG00000100348.51924.337602473.60110-0.362306.374705.19370K562MTPAP
TXN2ENSG00000100348.51851.925201432.836700.370102.611701.36870K562NONO
TXN2ENSG00000100348.52189.167803020.82610-0.464604.246103.21440K562PCBP3
TXN2ENSG00000100348.51732.691202317.00830-0.419205.410804.29110K562POLR2G
TXN2ENSG00000100348.53618.704602477.848600.546306.938605.53440K562PPIG
TXN2ENSG00000100348.52970.316203598.92130-0.276902.828802.00350K562PUF60
TXN2ENSG00000100348.53275.710303750.68820-0.195302.171301.31980K562PUM2
TXN2ENSG00000100348.52044.089901709.586300.257702.185201.30850K562RCC2
TXN2ENSG00000100348.5968.784001440.46610-0.572304.911003.82080K562RPS19
TXN2ENSG00000100348.51242.919001017.045500.289202.423201.62500K562SF3B4
TXN2ENSG00000100348.51938.377702778.49890-0.5195014.5560012.63870K562SRPK2
TXN2ENSG00000100348.51672.873701292.662500.371903.012102.15100K562TIA1
TXN2ENSG00000100348.52339.024801914.624300.288702.464501.58090K562TRIM56
TXN2ENSG00000100348.52584.511902914.12660-0.173201.936401.32750K562UPF1
TXN2ENSG00000100348.51891.510202634.26390-0.477902.944401.70070K562UTP3
TXN2ENSG00000100348.52281.439102593.01830-0.184702.233101.46600K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TXN2 is not available on ENCORE database.





9 RBPs can affect the splicing of TXN2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETXN2ENSG00000100348.5chr22-3687282136872903368630823686396436876621368767390.096000.000000.00040includedK562DHX30
SETXN2ENSG00000100348.5chr22-3687282136872903368630823686396436876621368768840.086000.000000.00020includedK562HNRNPL
SETXN2ENSG00000100348.5chr22-3687282136872903368630823686396436876621368766890.088000.000000.00193includedK562CPEB4
MXETXN2ENSG00000100348.5chr22-36872779368729033687662136876884368630823686396436877610368780770.096000.002880.064471includedHepG2XRN2
MXETXN2ENSG00000100348.5chr22-36872779368729033687662136876834368630923686396436877610368776810.160000.000000.000131includedK562SAFB
MXETXN2ENSG00000100348.5chr22-36872779368729033687662136876884368630823686396436877610368780770.173000.000000.000011includedK562SAFB
MXETXN2ENSG00000100348.5chr22-3687277936872903368766213687688436863082368639643687761036878077-0.114000.000630.081762includedHepG2DDX52
MXETXN2ENSG00000100348.5chr22-3687277936872903368766213687683436863092368639643687761036877681-0.053000.000530.076162includedHepG2DDX52
MXETXN2ENSG00000100348.5chr22-36872779368729033687662136876884368630823686396436877610368780770.086000.002910.051071includedK562PRPF8
MXETXN2ENSG00000100348.5chr22-36872779368729033687662136876834368630923686396436877610368776810.055000.000860.021671includedK562SUPV3L1
MXETXN2ENSG00000100348.5chr22-36872779368729033687662136876884368630823686396436877610368780770.169000.000000.000001includedK562SUPV3L1
MXETXN2ENSG00000100348.5chr22-36872779368729033687662136876884368630823686396436877610368780770.091000.006460.073591includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TXN2 is not avaliable on ENCORE database.