TP53BP1

General Information

Gene Name       : TP53BP1
Gene ID             : ENSG00000067369.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TP53BP1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TP53BP1ENSG00000067369.1312.1212.8712.49ENCSR000AEF
HepG2TP53BP1ENSG00000067369.1313.7614.8114.29ENCSR985KAT
K562TP53BP1ENSG00000067369.1319.3219.9019.61ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TP53BP1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TP53BP1 RNA is bound by 15 proteins.  







eCLIP assay for TP53BP1 is not avaliable on ENCORE database.





15 proteins are bound to TP53BP1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr154370551143705582-3'-UTR,CDS,intron-Distal,intron-Proximal5.249155.58150K562SF3B4
chr154369945043699526-3'-UTR,intron-Distal6.5905323.23488K562PUM2
chr154371428243714325-3'-UTR,CDS,intron-Distal,intron-Proximal4.704304.04372HepG2BCLAF1
chr154370858143708629-3'-UTR,CDS,intron-Distal,intron-Proximal4.756127.94672K562U2AF2
chr154369947143699536-3'-UTR,intron-Distal5.866467.71888HepG2SUB1
chr154371274343712794-3'-UTR,CDS,intron-Distal,intron-Proximal3.917833.05875K562RBM15
chr154370858243708631-3'-UTR,CDS,intron-Distal,intron-Proximal4.170773.02097K562U2AF1
chr154370549443705583-3'-UTR,CDS,intron-Distal,intron-Proximal4.061456.60968K562BUD13
chr154373372643733813-5'-UTR,CDS,intron-Distal,intron-Proximal3.930533.37563K562U2AF2
chr154373875943738816-5'-UTR,CDS,intron-Distal,intron-Proximal5.5439215.49786K562U2AF2
chr154378523243785277-5'-UTR,CDS,intron-Distal4.120223.82843HepG2PPIG
chr154372470943724750-5'-UTR,CDS,intron-Distal,intron-Proximal3.249776.18351K562YBX3
chr154372475043724757-5'-UTR,CDS,intron-Distal,intron-Proximal3.693666.20049K562YBX3
chr154372478443724795-5'-UTR,CDS,intron-Distal,intron-Proximal4.3665411.31430K562YBX3
chr154373371943733791-5'-UTR,CDS,intron-Distal,intron-Proximal3.172653.55660K562BUD13
chr154373873343738822-5'-UTR,CDS,intron-Distal,intron-Proximal5.1810223.03231HepG2U2AF2
chr154373877443738816-5'-UTR,CDS,intron-Distal,intron-Proximal3.989484.35112K562U2AF1
chr154372475743724784-5'-UTR,CDS,intron-Distal,intron-Proximal4.3015716.43977K562YBX3
chr154378387643783950-CDS,intron-Distal4.146365.14848K562ZNF622
chr154377309043773155-CDS,intron-Distal,intron-Proximal4.059409.74809K562ZNF622
chr154377220343772215-CDS,intron-Distal3.915933.28461K562BUD13
chr154377309143773180-CDS,intron-Distal,intron-Proximal3.436078.60702K562UCHL5
chr154377212943772214-CDS,intron-Distal3.8888611.09639K562ZNF622
chr154377164043771725-CDS,intron-Distal,intron-Proximal3.406846.21602K562ZNF622
chr154376765743767804-CDS,intron-Distal,intron-Proximal3.696678.62380K562PRPF8
chr154377309343773106-CDS,intron-Distal4.256603.06595HepG2BCLAF1
chr154377216743772215-CDS,intron-Distal4.635664.38106HepG2PPIG
chr154374840943748529-CDS,intron-Distal,intron-Proximal3.392297.21479K562UCHL5
chr154378448043784540-CDS,intron-Distal,intron-Proximal4.192894.55095K562YBX3
chr154374843543748485-CDS,intron-Distal,intron-Proximal4.372824.04372HepG2BCLAF1
chr154377205643772089-CDS,intron-Distal,intron-Proximal4.409623.77023K562ZNF622
chr154376773043767783-CDS,intron-Distal,intron-Proximal3.315224.22621HepG2PRPF8
chr154377308943773155-CDS,intron-Distal,intron-Proximal4.107367.98725K562BUD13
chr154377209443772174-CDS,intron-Distal3.153716.02234K562UCHL5
chr154376336343763426-intron-Distal4.532543.66668K562KHSRP
chr154370778243707792-intron-Distal,intron-Proximal3.986074.15711K562AQR
chr154373917243739229-intron-Distal,intron-Proximal3.288113.47285K562PRPF8
chr154370774843707782-intron-Distal,intron-Proximal4.549858.69247K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TP53BP1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TP53BP1 is not available on ENCORE database.

  • 88 RBPs can affect the levels of TP53BP1.  








The Knockdown/knockout RNA-Seq assay for TP53BP1 is not available on ENCORE database.





88 RBPs can affect the gene expression of TP53BP1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TP53BP1ENSG00000067369.91345.67900591.510201.1858015.8170014.65200HepG2AKAP1
TP53BP1ENSG00000067369.9761.43480489.429500.637505.262404.19610HepG2ASCC1
TP53BP1ENSG00000067369.9679.808701104.71800-0.700508.269107.30180HepG2BOP1
TP53BP1ENSG00000067369.9637.04530899.62950-0.497907.179206.20050HepG2CKAP4
TP53BP1ENSG00000067369.9681.041201014.18360-0.574505.356804.42980HepG2CPSF6
TP53BP1ENSG00000067369.9553.97630824.63760-0.573907.012905.40860HepG2YBX3
TP53BP1ENSG00000067369.9900.997001074.77230-0.254402.043001.47540HepG2CELF1
TP53BP1ENSG00000067369.9981.269201155.59460-0.235902.359401.66670HepG2DAZAP1
TP53BP1ENSG00000067369.91136.41070825.203800.461604.158803.34330HepG2DDX21
TP53BP1ENSG00000067369.91092.47600566.631500.9470011.4940010.29930HepG2DDX3X
TP53BP1ENSG00000067369.9772.77060563.658000.455103.849602.27280HepG2DDX52
TP53BP1ENSG00000067369.9601.62060777.78180-0.370502.323701.39770HepG2DDX5
TP53BP1ENSG00000067369.9583.40570780.97350-0.420803.168802.12280HepG2DHX30
TP53BP1ENSG00000067369.9655.18050860.89050-0.393903.979703.19660HepG2DKC1
TP53BP1ENSG00000067369.9586.76670809.71190-0.464604.865303.95620HepG2DNAJC21
TP53BP1ENSG00000067369.9665.40260802.59160-0.270402.460301.83920HepG2DNAJC2
TP53BP1ENSG00000067369.9884.89460672.568900.395702.572901.68130HepG2EEF2
TP53BP1ENSG00000067369.9673.38760467.923500.525103.482202.82180HepG2EIF2S1
TP53BP1ENSG00000067369.9724.55550503.469700.525102.776402.08690HepG2EIF4B
TP53BP1ENSG00000067369.9717.613101092.14250-0.605906.031004.85080HepG2EIF4G2
TP53BP1ENSG00000067369.92137.835701676.176900.350905.290104.50610HepG2ETF1
TP53BP1ENSG00000067369.91343.92650949.648200.500903.857602.96130HepG2FIP1L1
TP53BP1ENSG00000067369.9603.95560321.321000.910303.901002.97710HepG2FUBP3
TP53BP1ENSG00000067369.91162.37470521.721301.1556017.1569015.59820HepG2FXR1
TP53BP1ENSG00000067369.9741.11880483.990000.614604.700203.84270HepG2G3BP1
TP53BP1ENSG00000067369.91203.97580822.254400.550004.997103.62100HepG2GNB2L1
TP53BP1ENSG00000067369.9833.282401407.29520-0.7560016.8288015.25760HepG2HNRNPF
TP53BP1ENSG00000067369.9685.45140490.044100.484003.344402.57940HepG2HNRNPK
TP53BP1ENSG00000067369.9704.111201052.64320-0.5801010.110208.89860HepG2HNRNPL
TP53BP1ENSG00000067369.9701.196401097.11980-0.645805.904505.02080HepG2HNRNPLL
TP53BP1ENSG00000067369.9773.472601385.78450-0.8413015.3234013.76870HepG2IGF2BP1
TP53BP1ENSG00000067369.9987.75330461.669501.097205.116703.79590HepG2IGF2BP3
TP53BP1ENSG00000067369.91078.95530922.670100.225602.300301.62460HepG2ILF2
TP53BP1ENSG00000067369.91183.60310768.812600.622408.051506.73760HepG2MSI2
TP53BP1ENSG00000067369.9996.61460537.196500.891509.782308.63300HepG2NCBP2
TP53BP1ENSG00000067369.9943.329201145.88790-0.280602.268801.57850HepG2NOL12
TP53BP1ENSG00000067369.9614.71860972.82190-0.662206.661605.52760HepG2NSUN2
TP53BP1ENSG00000067369.9825.56620509.748400.6955010.817409.74430HepG2PCBP1
TP53BP1ENSG00000067369.9568.88180805.65290-0.502005.545804.53360HepG2PPIL4
TP53BP1ENSG00000067369.9969.45460518.716900.9021017.4699016.32290HepG2PTBP1
TP53BP1ENSG00000067369.9579.627001093.86390-0.9162013.9842012.78500HepG2PUF60
TP53BP1ENSG00000067369.91463.340801160.342700.334603.308102.57540HepG2PUM2
TP53BP1ENSG00000067369.9895.29240561.721800.672408.734707.71980HepG2QKI
TP53BP1ENSG00000067369.9441.08500785.52260-0.832604.821103.90540HepG2RAVER1
TP53BP1ENSG00000067369.91707.310201400.977000.285202.852002.32750HepG2RBM22
TP53BP1ENSG00000067369.9691.67020509.821800.440003.458902.71140HepG2RBM25
TP53BP1ENSG00000067369.9687.38150971.30280-0.498803.957802.75740HepG2RBM27
TP53BP1ENSG00000067369.9550.00530788.73970-0.520103.090001.96810HepG2RCC2
TP53BP1ENSG00000067369.91255.41150577.258101.1208028.7613027.39710HepG2NELFE
TP53BP1ENSG00000067369.9897.51390537.680900.739108.515907.52350HepG2RECQL
TP53BP1ENSG00000067369.9857.040101515.99520-0.8228012.6335011.36340HepG2RPLP0
TP53BP1ENSG00000067369.9330.16170771.69760-1.2249011.422909.64220HepG2RPS10
TP53BP1ENSG00000067369.9673.85100531.260700.342902.215801.65890HepG2RPS19
TP53BP1ENSG00000067369.9540.99480706.87790-0.385802.072401.38300HepG2RRP9
TP53BP1ENSG00000067369.9465.30320804.40600-0.7898013.8000012.52370HepG2SAFB2
TP53BP1ENSG00000067369.9460.233001085.91970-1.2385021.2594019.50690HepG2SF3B1
TP53BP1ENSG00000067369.9832.469801048.87790-0.333403.771802.97300HepG2SLBP
TP53BP1ENSG00000067369.91134.75830938.063500.274503.157202.47740HepG2SMN1
TP53BP1ENSG00000067369.91965.169701582.357600.312504.566003.96880HepG2SRFBP1
TP53BP1ENSG00000067369.91477.37940563.663701.3900049.1455047.69390HepG2SRSF1
TP53BP1ENSG00000067369.9759.895601168.48800-0.620804.701003.36350HepG2SRSF3
TP53BP1ENSG00000067369.9757.494301382.61950-0.8681021.2004019.60480HepG2SRSF7
TP53BP1ENSG00000067369.9643.28310458.588600.488205.387204.66120HepG2SRSF9
TP53BP1ENSG00000067369.9886.027301373.87100-0.6328012.6969011.75670HepG2SSB
TP53BP1ENSG00000067369.9506.60360734.10090-0.535102.639601.46880HepG2SUB1
TP53BP1ENSG00000067369.91758.274701228.298500.517403.893503.17830HepG2SUCLG1
TP53BP1ENSG00000067369.9920.98030506.701400.8619014.8732013.72670HepG2TAF15
TP53BP1ENSG00000067369.9793.661801069.40810-0.430203.403702.60850HepG2TARDBP
TP53BP1ENSG00000067369.9667.84780885.55490-0.407104.673003.97870HepG2TRIM56
TP53BP1ENSG00000067369.9365.82670544.77900-0.574504.076003.15470HepG2UCHL5
TP53BP1ENSG00000067369.9694.53320846.70300-0.285802.445401.87480HepG2UTP3
TP53BP1ENSG00000067369.9564.78930907.84320-0.684706.367005.28260HepG2XRN2
TP53BP1ENSG00000067369.91736.434401388.594000.322402.742301.56760K562AARS
TP53BP1ENSG00000067369.93021.346502664.702200.181102.204301.68840K562AGGF1
TP53BP1ENSG00000067369.94046.069904699.33010-0.215902.482501.55950K562CELF1
TP53BP1ENSG00000067369.92746.221602001.099300.456608.361107.21260K562EIF2S2
TP53BP1ENSG00000067369.91490.062101915.04610-0.362003.233002.34860K562EIF4A3
TP53BP1ENSG00000067369.92193.966601700.332700.367603.553101.72030K562FASTKD2
TP53BP1ENSG00000067369.91491.569901930.76210-0.372303.367502.42470K562FIP1L1
TP53BP1ENSG00000067369.92004.076201525.428700.393603.527402.55760K562FMR1
TP53BP1ENSG00000067369.91793.021801405.056000.351703.783402.18020K562FUS
TP53BP1ENSG00000067369.91578.679001991.57670-0.335204.193203.47100K562FXR1
TP53BP1ENSG00000067369.91667.058102098.35830-0.332003.395102.13140K562GLRX3
TP53BP1ENSG00000067369.91889.140302666.66370-0.497306.667405.48830K562GRSF1
TP53BP1ENSG00000067369.91563.817802505.34710-0.6799011.468909.67810K562MAGOH
TP53BP1ENSG00000067369.91905.856002206.17800-0.211102.411401.65520K562MTPAP
TP53BP1ENSG00000067369.92354.225501912.214100.299903.204501.87570K562NCBP2
TP53BP1ENSG00000067369.92038.363302451.10560-0.266004.791703.84700K562NSUN2
TP53BP1ENSG00000067369.91612.119102191.83160-0.443204.376203.31240K562PPIG
TP53BP1ENSG00000067369.93103.133404169.31880-0.426105.247204.12650K562PUF60
TP53BP1ENSG00000067369.91919.961102333.82480-0.281602.211501.46390K562RBM22
TP53BP1ENSG00000067369.91496.510801984.86100-0.407405.060003.88490K562SF3B4
TP53BP1ENSG00000067369.91303.313601726.79350-0.405902.639801.61740K562SRSF4
TP53BP1ENSG00000067369.91778.171102415.00010-0.441604.350803.45710K562TARDBP
TP53BP1ENSG00000067369.92295.098101910.964100.264202.513201.74730K562U2AF2
TP53BP1ENSG00000067369.92036.320302312.67190-0.183602.053401.31690K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TP53BP1 is not available on ENCORE database.





8 RBPs can affect the splicing of TP53BP1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETP53BP1ENSG00000067369.9chr15-437132224371337243712502437129334371405243714324-0.250000.000100.00325excludedK562SRSF1
SETP53BP1ENSG00000067369.9chr15-4373896343739112437385844373878843739563437396830.102000.001540.02988includedK562SF3B4
SETP53BP1ENSG00000067369.9chr15-437243914372487543720213437203664373052143730614-0.139000.000140.00418excludedK562SF3B4
SETP53BP1ENSG00000067369.9chr15-4373896343739112437385844373878843739563437396830.188000.000000.00000includedK562AQR
SETP53BP1ENSG00000067369.9chr15-437243914372487543720213437203664373052143730614-0.161000.000000.00000excludedK562AQR
SETP53BP1ENSG00000067369.9chr15-437697904376995743762055437622644377159443771724-0.437000.000000.00001excludedK562AQR
SETP53BP1ENSG00000067369.9chr15-437337234373378143730521437306144373858443738788-0.090000.000160.00372excludedK562PUS1
SETP53BP1ENSG00000067369.9chr15-437132224371337243712502437129334371405243714324-0.246000.004800.07875excludedK562U2AF1
SETP53BP1ENSG00000067369.9chr15-437243914372487543720213437203664373052143730614-0.201000.001200.03532excludedHepG2SF3A3
SETP53BP1ENSG00000067369.9chr15-437132224371337243712502437129334371405243714324-0.331000.000420.00961excludedK562U2AF2
SETP53BP1ENSG00000067369.9chr15-4373896343739112437385844373878843739563437396830.083000.001280.04565includedK562TARDBP
A3SSTP53BP1ENSG00000067369.9chr15-4373052143730647437305214373061443733723437337810.099000.000010.00006longerK562AQR
A3SSTP53BP1ENSG00000067369.9chr15-4376776243767935437677624376789243769790437699900.085000.001440.00963longerK562AQR
A3SSTP53BP1ENSG00000067369.9chr15-4376979043769990437697904376995743771594437717240.103000.007720.04225longerK562AQR
A3SSTP53BP1ENSG00000067369.9chr15-4372021343720410437202134372036643724391437248750.052000.000180.00147longerK562AQR
A3SSTP53BP1ENSG00000067369.9chr15-4378386643783964437838664378395143784199437842930.100000.013860.06992longerK562AQR
A3SSTP53BP1ENSG00000067369.9chr15-4370854143708696437085414370861443712502437129330.087000.000000.00000longerK562AQR
A3SSTP53BP1ENSG00000067369.9chr15-4370531643705556437053164370553243707791437080070.076000.000080.00067longerK562AQR
A3SSTP53BP1ENSG00000067369.9chr15-4373858443738826437385844373878843739563437396830.147000.000010.00007longerK562AQR
A3SSTP53BP1ENSG00000067369.9chr15-4370014043700309437001404370028643701094437012940.064000.000030.00026longerK562AQR
MXETP53BP1ENSG00000067369.9chr15-43720213437203664373052143730647437140524371432443733723437337810.059000.000350.003621includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TP53BP1 is not avaliable on ENCORE database.