TIMM50

General Information

Gene Name       : TIMM50
Gene ID             : ENSG00000105197.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TIMM50)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TIMM50ENSG00000105197.1027.6146.5637.09ENCSR000AEF
HepG2TIMM50ENSG00000105197.1070.3358.3464.34ENCSR985KAT
K562TIMM50ENSG00000105197.10113.63121.41117.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TIMM50 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TIMM50 RNA is bound by 19 proteins.  







eCLIP assay for TIMM50 is not avaliable on ENCORE database.





19 proteins are bound to TIMM50 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr193997704439977121+3'-UTR,CDS,intron-Distal3.969153.61890HepG2G3BP1
chr193998262639982654+3'-UTR4.578936.81876K562UPF1
chr193998294739983003+3'-UTR5.9104112.69138K562UPF1
chr193997918039979285+3'-UTR,CDS4.673415.48383HepG2LARP4
chr193997920239979277+3'-UTR,CDS4.413766.14390K562PABPC4
chr193998289139982904+3'-UTR4.680704.90799K562UPF1
chr193997710539977192+3'-UTR,CDS,intron-Distal,intron-Proximal3.080484.29223HepG2PRPF8
chr193997927539979286+3'-UTR,CDS,intron-Proximal3.927103.46958K562YBX3
chr193998043039980464+3'-UTR,5'-UTR,CDS4.5863726.46298K562YBX3
chr193997707239977126+3'-UTR,CDS,intron-Distal3.3836011.12108K562YBX3
chr193997873939978860+3'-UTR,CDS,intron-Proximal3.286104.39623HepG2PPIG
chr193998283339982860+3'-UTR3.384056.06342K562UPF1
chr193998252439982653+3'-UTR,intron-Proximal4.4585029.81147K562AKAP1
chr193998042039980430+3'-UTR,CDS4.3449022.79023K562YBX3
chr193997875239978822+3'-UTR,CDS3.278555.57913K562PABPC4
chr193997703839977056+3'-UTR,CDS,intron-Distal4.5170618.74635K562YBX3
chr193998265739982733+3'-UTR5.4206919.33267K562UPF1
chr193998039239980420+3'-UTR,CDS3.933247.64164K562YBX3
chr193998039239980473+3'-UTR,5'-UTR,CDS3.848093.33617HepG2PABPN1
chr193997924839979275+3'-UTR,CDS3.269704.11795K562YBX3
chr193998296239983019+3'-UTR3.599463.84723K562ILF3
chr193998046139980577+3'-UTR,5'-UTR3.879319.16632K562PABPC4
chr193997703539977038+3'-UTR,CDS,intron-Distal,intron-Proximal4.6867024.09950K562YBX3
chr193997690339976931+3'-UTR,CDS,intron-Distal4.7381024.51712K562YBX3
chr193997928239979336+3'-UTR,CDS,intron-Proximal4.035844.52312K562AQR
chr193997266339972766+5'-UTR,CDS,intron-Distal,intron-Proximal3.160705.25094K562PRPF8
chr193998102939981163+5'-UTR,intron-Distal,intron-Proximal4.5621717.10175HepG2UPF1
chr193997259539972673+5'-UTR,CDS,intron-Distal3.878153.35081HepG2G3BP1
chr193997266539972758+5'-UTR,CDS,intron-Distal,intron-Proximal3.158643.13705K562BUD13
chr193997352239973617+5'-UTR,CDS,intron-Distal,intron-Proximal3.035693.17635HepG2PPIG
chr193998104039981075+5'-UTR,intron-Proximal5.5514333.73654K562UPF1
chr193997156539971602+5'-UTR,CDS,intron-Proximal3.569915.97131K562DDX3X
chr193997149739971565+5'-UTR,CDS3.440845.67913K562DDX3X
chr193998103439981091+5'-UTR,intron-Proximal4.8671025.71819K562AKAP1
chr193998102939981110+5'-UTR,intron-Proximal3.868713.79323HepG2STAU2
chr193998102939981040+5'-UTR4.7277716.98297K562UPF1
chr193997377539973818+CDS,intron-Distal,intron-Proximal4.073673.20743HepG2PPIG
chr193997355339973612+CDS,intron-Distal,intron-Proximal4.2165311.41273HepG2PRPF8
chr193997355139973593+CDS,intron-Distal,intron-Proximal4.787883.53505HepG2EFTUD2
chr193997374839973784+CDS,intron-Distal,intron-Proximal4.929355.17615K562AQR
chr193997358539973603+CDS,intron-Distal,intron-Proximal4.842336.48405K562AQR
chr193997355439973585+CDS,intron-Distal,intron-Proximal4.271115.83621K562AQR
chr193997356639973595+CDS,intron-Distal,intron-Proximal4.332273.59236HepG2AQR
chr193997354839973629+CDS,intron-Distal,intron-Proximal3.006265.17453K562PRPF8
chr193997373839973819+CDS,intron-Distal,intron-Proximal4.490833.93614HepG2AQR
chr193997372339973836+CDS,intron-Distal,intron-Proximal5.607259.62108K562SF3B4
chr193997378439973842+CDS,intron-Distal,intron-Proximal4.018348.29266K562AQR
chr193998223339982274+intron-Distal4.3385011.27741K562AKAP1
chr193997407539974157+intron-Distal3.881653.06084HepG2HNRNPK
chr193998354739983628+intron-Distal5.8378513.64218K562UPF1
chr193998219939982221+intron-Distal3.493737.13412K562ILF3
chr193998216839982218+intron-Distal4.5754123.32087K562AKAP1
chr193997560739975663+intron-Distal3.000513.00589HepG2HNRNPC
chr193998208539982132+intron-Distal6.6337016.39444K562AKAP1
chr193998122439981259+intron-Distal4.530167.92165K562AKAP1
chr193998122039981266+intron-Distal4.7792410.23575K562UPF1
chr193998217239982227+intron-Distal4.8402322.15379K562UPF1
chr193998129439981337+intron-Distal5.557448.05720K562UPF1
chr193997713539977175+intron-Distal,intron-Proximal4.384433.12843K562PRPF8
chr193998230039982390+intron-Distal4.3458820.84603K562AKAP1
chr193998107439981173+intron-Distal,intron-Proximal4.8210411.88181HepG2AKAP1
chr193998121739981316+intron-Distal5.553976.96152HepG2UPF1
chr193998109139981175+intron-Distal,intron-Proximal4.6830423.32087K562AKAP1
chr193998107539981184+intron-Distal,intron-Proximal5.6577939.77259K562UPF1
chr193998162739981676+intron-Distal5.5941414.71049K562AKAP1
chr193997392939973977+intron-Distal4.284663.49003K562PRPF8
chr193997270239972751+intron-Distal,intron-Proximal4.817493.69482HepG2RBM22
chr193998232539982386+intron-Distal6.2656616.29100K562UPF1
chr193998355839983614+intron-Distal3.929346.97411K562AKAP1
chr193998222739982273+intron-Distal4.4474112.76076K562UPF1
chr193998217239982251+intron-Distal4.455605.27745HepG2ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TIMM50 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TIMM50 is not available on ENCORE database.

  • 74 RBPs can affect the levels of TIMM50.  








The Knockdown/knockout RNA-Seq assay for TIMM50 is not available on ENCORE database.





74 RBPs can affect the gene expression of TIMM50 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TIMM50ENSG00000105197.6603.68490777.72380-0.365503.458902.61270HepG2AKAP8L
TIMM50ENSG00000105197.6681.14870958.01370-0.492103.707102.80200HepG2ASCC1
TIMM50ENSG00000105197.6995.743101213.84750-0.285702.753102.06960HepG2AUH
TIMM50ENSG00000105197.6435.00430680.30120-0.645105.134703.94570HepG2BCLAF1
TIMM50ENSG00000105197.6465.91960627.39870-0.429303.354402.00960HepG2BUD13
TIMM50ENSG00000105197.6507.69630655.55510-0.368802.459701.72940HepG2CALR
TIMM50ENSG00000105197.6354.48200548.22740-0.629104.714103.83750HepG2CPSF6
TIMM50ENSG00000105197.6460.90240588.98560-0.353802.111001.50950HepG2DDX21
TIMM50ENSG00000105197.6523.39470769.88370-0.556704.041403.12590HepG2DDX55
TIMM50ENSG00000105197.6599.43770740.66420-0.305202.406401.76730HepG2DKC1
TIMM50ENSG00000105197.6703.62920915.87300-0.380302.350501.80130HepG2EIF2S1
TIMM50ENSG00000105197.6779.48180985.05400-0.337702.210201.47680HepG2EIF4G2
TIMM50ENSG00000105197.61186.664601393.66770-0.232002.369001.80480HepG2ETF1
TIMM50ENSG00000105197.6470.61240640.77300-0.445302.555401.33210HepG2FKBP4
TIMM50ENSG00000105197.6704.79360947.35130-0.426702.767902.10260HepG2G3BP1
TIMM50ENSG00000105197.6471.92630621.40270-0.397002.104201.54160HepG2GPKOW
TIMM50ENSG00000105197.6700.38530957.91130-0.451705.189803.97690HepG2HNRNPA2B1
TIMM50ENSG00000105197.6444.42970593.02110-0.416102.402801.81110HepG2HNRNPLL
TIMM50ENSG00000105197.6703.02030962.91040-0.453803.158702.44320HepG2IGF2BP2
TIMM50ENSG00000105197.6395.17450525.86710-0.412202.338401.64830HepG2NSUN2
TIMM50ENSG00000105197.6666.50530936.34650-0.490403.592402.77630HepG2PABPC4
TIMM50ENSG00000105197.6400.97930593.72570-0.566304.036803.08370HepG2PRPF8
TIMM50ENSG00000105197.6583.60710973.71750-0.7385012.0188011.03770HepG2PTBP1
TIMM50ENSG00000105197.6735.61140986.60780-0.423503.537002.87410HepG2PUF60
TIMM50ENSG00000105197.6484.74850788.55290-0.7020010.739709.66260HepG2PUS1
TIMM50ENSG00000105197.6746.501401054.51280-0.498405.588304.74670HepG2QKI
TIMM50ENSG00000105197.6972.318201164.84660-0.260602.168601.69490HepG2RBM22
TIMM50ENSG00000105197.6672.50240957.05600-0.509104.963404.08440HepG2RBM25
TIMM50ENSG00000105197.6737.357501083.63560-0.555407.770206.94510HepG2NELFE
TIMM50ENSG00000105197.6837.955701009.29270-0.268402.274101.70900HepG2RECQL
TIMM50ENSG00000105197.61088.55530725.825300.584604.277903.42950HepG2SF3A3
TIMM50ENSG00000105197.6743.341401013.72580-0.447605.326304.55170HepG2SF3B4
TIMM50ENSG00000105197.6403.65570653.08690-0.694103.915702.97830HepG2SNRNP70
TIMM50ENSG00000105197.6822.780801058.12650-0.362903.946303.40660HepG2SRSF1
TIMM50ENSG00000105197.6670.27850816.24610-0.284202.286501.64920HepG2SRSF7
TIMM50ENSG00000105197.6522.95870860.85620-0.7191012.0773011.06840HepG2SRSF9
TIMM50ENSG00000105197.6825.981401142.28890-0.467706.805306.06940HepG2SSB
TIMM50ENSG00000105197.6364.84300766.35590-1.0707011.8102010.57400HepG2SUPV3L1
TIMM50ENSG00000105197.6544.24690951.13040-0.8054012.8679011.79260HepG2TAF15
TIMM50ENSG00000105197.6556.31290723.38490-0.378902.466501.87100HepG2U2AF1
TIMM50ENSG00000105197.6515.18540643.69660-0.321302.603701.92240HepG2UPF1
TIMM50ENSG00000105197.6957.58040621.463000.623609.847108.82890HepG2UTP3
TIMM50ENSG00000105197.6551.85980660.34630-0.258901.944301.36620HepG2ZC3H8
TIMM50ENSG00000105197.61786.361202384.65420-0.416804.012102.51550K562ABCF1
TIMM50ENSG00000105197.62036.778601453.565500.486609.390808.42470K562AGGF1
TIMM50ENSG00000105197.63360.307002785.776700.270402.165301.63510K562AQR
TIMM50ENSG00000105197.6808.515801326.66200-0.714506.435105.09340K562BOP1
TIMM50ENSG00000105197.6862.341701410.68900-0.710105.964804.81800K562CPSF6
TIMM50ENSG00000105197.63234.462803866.16490-0.257402.839801.85410K562CELF1
TIMM50ENSG00000105197.62680.918402173.246500.302803.560902.83410K562DDX47
TIMM50ENSG00000105197.62180.224801627.572100.421706.680105.22700K562DKC1
TIMM50ENSG00000105197.61611.985502511.55330-0.6397014.9072013.43960K562EIF2S2
TIMM50ENSG00000105197.61492.83520972.370100.618409.776208.27700K562EIF3G
TIMM50ENSG00000105197.61591.381001253.198100.344602.800001.97360K562EIF4A3
TIMM50ENSG00000105197.61057.549501435.21360-0.440502.673401.83370K562FMR1
TIMM50ENSG00000105197.6774.664101216.41700-0.651005.281403.97420K562FTO
TIMM50ENSG00000105197.62235.984701303.262000.7787012.8094011.60520K562FXR1
TIMM50ENSG00000105197.6414.90160758.40610-0.870207.344306.07510K562G3BP2
TIMM50ENSG00000105197.6997.860501346.91410-0.432702.967502.14530K562GPKOW
TIMM50ENSG00000105197.61181.744601554.12520-0.395203.013402.39400K562HNRNPC
TIMM50ENSG00000105197.61961.871001410.076500.476404.050402.91020K562HNRNPM
TIMM50ENSG00000105197.62001.385602452.55590-0.293303.369702.38630K562HNRNPU
TIMM50ENSG00000105197.6793.477201178.72510-0.571004.398202.52270K562KHDRBS1
TIMM50ENSG00000105197.6697.308501149.95700-0.721705.832204.41940K562KRR1
TIMM50ENSG00000105197.61872.472301206.500400.634009.524007.90550K562MAGOH
TIMM50ENSG00000105197.61516.301901203.977000.332603.007602.04180K562MATR3
TIMM50ENSG00000105197.62745.868103351.30330-0.287502.447501.38740K562MSI2
TIMM50ENSG00000105197.61745.217202061.04110-0.240003.780602.92400K562NSUN2
TIMM50ENSG00000105197.61298.316802195.20820-0.757709.565308.02860K562PCBP3
TIMM50ENSG00000105197.61154.113901683.76650-0.544907.641306.33400K562POLR2G
TIMM50ENSG00000105197.62545.100101946.128800.387003.617202.66060K562PPIG
TIMM50ENSG00000105197.61717.241401172.227900.550707.687506.61780K562PTBP1
TIMM50ENSG00000105197.63067.842403575.12890-0.220802.590801.66000K562PUM2
TIMM50ENSG00000105197.6905.030701280.76900-0.501003.608102.48950K562SF3B1
TIMM50ENSG00000105197.6653.60460892.85790-0.450003.441701.63350K562SND1
TIMM50ENSG00000105197.61952.433601149.230100.7645013.9271012.33610K562SRSF1
TIMM50ENSG00000105197.61506.053101837.01020-0.286603.120401.87080K562SRSF7
TIMM50ENSG00000105197.61513.985701916.49430-0.340103.538101.80200K562SRSF9
TIMM50ENSG00000105197.6747.273901003.04020-0.424703.561002.07800K562SSB
TIMM50ENSG00000105197.61009.010401372.98850-0.444403.411002.27140K562SUPV3L1
TIMM50ENSG00000105197.62126.010801688.907400.332003.532802.60480K562SYNCRIP
TIMM50ENSG00000105197.6427.84660744.47120-0.799103.995802.10650K562TAF15
TIMM50ENSG00000105197.6557.30350759.29890-0.446203.970203.01060K562U2AF2
TIMM50ENSG00000105197.6986.497901453.30620-0.559005.745804.22950K562UCHL5
TIMM50ENSG00000105197.61769.068702185.36400-0.304904.619103.71630K562UPF1
TIMM50ENSG00000105197.61394.337801869.94950-0.423404.803003.63320K562WDR3
TIMM50ENSG00000105197.62004.915203138.61400-0.646606.976805.50680K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TIMM50 is not available on ENCORE database.





13 RBPs can affect the splicing of TIMM50 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETIMM50ENSG00000105197.6chr19+399725223997267339971492399716013997352439973556-0.139000.001210.02449excludedK562SF3B4
SETIMM50ENSG00000105197.6chr19+399725223997267339971492399716013997352439973556-0.234000.000020.00059excludedHepG2U2AF1
SETIMM50ENSG00000105197.6chr19+399761833997624239973774399737963997632739976447-0.083000.000000.00006excludedK562AQR
SETIMM50ENSG00000105197.6chr19+399725223997267339971492399716013997352439973556-0.054000.003430.09788excludedK562FXR1
SETIMM50ENSG00000105197.6chr19+399725223997267339971492399716013997352439973556-0.151000.000110.00512excludedHepG2SF3A3
SETIMM50ENSG00000105197.6chr19+399761833997624239973774399737963997632739976447-0.068000.000030.00161excludedHepG2SF3A3
SETIMM50ENSG00000105197.6chr19+399725223997267339971492399716013997352439973556-0.180000.000020.00170excludedK562SF3B1
SETIMM50ENSG00000105197.6chr19+399725223997267339971492399716013997352439973556-0.150000.000200.04908excludedK562SAFB
SETIMM50ENSG00000105197.6chr19+399725223997267339971497399716013997352439973556-0.103000.002480.04048excludedK562HNRNPC
A5SSTIMM50ENSG00000105197.6chr19+3997156739971786399715673997160139972522399726730.072000.000000.00000longerK562AQR
MXETIMM50ENSG00000105197.6chr19+39973524399735563997618339976242399725223997267339976327399764470.143000.001050.023351includedHepG2FTO
MXETIMM50ENSG00000105197.6chr19+3997352439973556399761833997624239972522399726733997632739976447-0.136000.002560.040042includedK562U2AF1
MXETIMM50ENSG00000105197.6chr19+3997352439973556399761833997624239972522399726733997632739976447-0.119000.003010.071382includedK562XRN2
MXETIMM50ENSG00000105197.6chr19+39973669399737963997618339976242399735243997355639976327399764470.082000.000000.000021includedK562AQR
MXETIMM50ENSG00000105197.6chr19+39973774399737963997618339976242399725223997267339976327399764470.133000.000000.000011includedK562AQR
MXETIMM50ENSG00000105197.6chr19+3997618339976242399763273997646639973774399737963997682639976931-0.100000.000000.000022includedK562AQR
MXETIMM50ENSG00000105197.6chr19+39973774399737963997618339976242399735243997360339976327399764470.113000.000170.010161includedHepG2SF3A3
MXETIMM50ENSG00000105197.6chr19+3997352439973556399761833997624239972522399726733997632739976447-0.117000.001370.057392includedHepG2DROSHA
MXETIMM50ENSG00000105197.6chr19+39973524399735563997618339976242399725223997267339976327399764470.086000.001130.030041includedK562FXR2
MXETIMM50ENSG00000105197.6chr19+39972522399726733997377439973796399714713997160139976183399762420.066000.000010.008331includedK562CPEB4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TIMM50 is not avaliable on ENCORE database.