THEM4

General Information

Gene Name : THEM4
Gene ID : ENSG00000159445.12
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: THEM4)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	THEM4	ENSG00000159445.12	16.92	17.72	17.32	ENCSR000AEF
HepG2	THEM4	ENSG00000159445.12	11.98	15.69	13.84	ENCSR985KAT
K562	THEM4	ENSG00000159445.12	33.02	32.48	32.75	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for THEM4 is not avaliable on ENCORE database.

Proteins bound to RNA

THEM4 RNA is bound by 12 proteins.

CanvasJS.com

eCLIP assay for THEM4 is not avaliable on ENCORE database.

12 proteins are bound to THEM4 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	151867397	151867497	-	3'-UTR,CDS,intron-Distal,intron-Proximal	6.74429	23.05208	K562	PRPF8
chr1	151866166	151866236	-	intron-Distal	5.92756	17.58839	K562	PTBP1
chr1	151866168	151866236	-	intron-Distal	4.31675	8.55014	HepG2	PTBP1
chr1	151861852	151861914	-	intron-Distal,intron-Proximal	5.08994	5.90023	K562	SF3B4
chr1	151846758	151846821	-	3'-UTR,intron-Distal,intron-Proximal	4.31204	5.43239	K562	YBX3
chr1	151881829	151881878	-	CDS,intron-Distal	4.70979	5.07098	K562	DDX3X
chr1	151861683	151861824	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.63609	4.34038	HepG2	BCLAF1
chr1	151871479	151871525	-	intron-Distal	4.32561	4.27460	K562	HNRNPM
chr1	151864313	151864400	-	intron-Distal	3.95082	3.76275	K562	PTBP1
chr1	151867439	151867587	-	CDS,intron-Distal,intron-Proximal	3.92755	3.56019	HepG2	GRWD1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 15 entries

eCLIP assay for THEM4 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for THEM4 is not available on ENCORE database.
73 RBPs can affect the levels of THEM4.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for THEM4 is not available on ENCORE database.

73 RBPs can affect the gene expression of THEM4 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
THEM4	ENSG00000159445.8	276.04590	844.48150	-1.61320	28.04050	26.29330	K562	PUS1
THEM4	ENSG00000159445.8	323.73420	818.22910	-1.33770	26.39760	24.75580	K562	AGGF1
THEM4	ENSG00000159445.8	557.38980	279.81100	0.99410	14.36380	13.16030	HepG2	UTP3
THEM4	ENSG00000159445.8	429.43860	851.38470	-0.98740	14.03990	12.39160	K562	AKAP8L
THEM4	ENSG00000159445.8	378.59390	822.70270	-1.11970	12.76710	11.49350	K562	RBM15
THEM4	ENSG00000159445.8	545.59480	247.48990	1.14040	9.89850	8.95880	HepG2	AKAP1
THEM4	ENSG00000159445.8	566.99530	916.27490	-0.69240	10.72730	8.77060	K562	DKC1
THEM4	ENSG00000159445.8	645.77810	1112.84060	-0.78510	10.28690	8.53140	K562	FIP1L1
THEM4	ENSG00000159445.8	752.63500	437.71540	0.78190	8.73260	7.73030	K562	FXR1
THEM4	ENSG00000159445.8	637.79470	1012.25200	-0.66640	8.17240	6.44280	K562	MBNL1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 79 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for THEM4 is not available on ENCORE database.

9 RBPs can affect the splicing of THEM4 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	-0.34200	0.00000	0.00000	excluded	K562	SRSF1
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	-0.40100	0.00000	0.00000	excluded	K562	PRPF8
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	-0.35000	0.00000	0.00010	excluded	K562	XRCC6
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	-0.44600	0.00000	0.00000	excluded	K562	FXR1
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	-0.43000	0.00000	0.00000	excluded	HepG2	SRSF1
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	0.28500	0.00002	0.00166	included	K562	HNRNPU
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	-0.23400	0.00003	0.00243	excluded	K562	PTBP1
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	0.35300	0.00023	0.05476	included	K562	WDR3
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	-0.41500	0.00034	0.02615	excluded	HepG2	NCBP2
SE	THEM4	ENSG00000159445.8	chr1	-	151862458	151862690	151861689	151861849	151867483	151867670	0.17900	0.00574	0.05210	included	K562	AQR

Showing 1 to 10 of 10 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

THEM4

General Information

Functions

Localization

Domains (AlphaFold: THEM4)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for THEM4 is not avaliable on ENCORE database.

12 proteins are bound to THEM4 RNA:

eCLIP assay for THEM4 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for THEM4 is not available on ENCORE database.

73 RBPs can affect the gene expression of THEM4 :

The Knockdown/knockout RNA-Seq assay for THEM4 is not available on ENCORE database.

9 RBPs can affect the splicing of THEM4 :

The Knockdown/knockout RNA-Seq assay for THEM4 is not avaliable on ENCORE database.