SSU72

General Information

Gene Name : SSU72
Gene ID : ENSG00000160075.11
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SSU72)

Not Available

Antibody Validation

Cell Signaling Technology: 12816S

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SSU72	ENSG00000160075.11	42.12	57.17	49.64	ENCSR000AEF
HepG2	SSU72	ENSG00000160075.11	56.74	63.36	60.05	ENCSR985KAT
K562	SSU72	ENSG00000160075.11	132.81	125.72	129.26	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SSU72		12816S	1			Submitted, ENCORE2	BGHcLV43-53, Submitted, ENCORE2	BGKcLV42-89, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
SSU72	K562	CRISPR			SSU72-BGKcLV42-89,SSU72-BGKcLV42-90	NT-BGKcLV42-1,NT-BGKcLV42-2	78.0,82.6	Sequenced	ENCORE2
SSU72	HepG2	CRISPR			SSU72-BGHcLV43-53,SSU72-BGHcLV43-54	NT-BGHcLV43-1,NT-BGHcLV43-2	66.6,66.3	Sequenced	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SSU72	Product_ID: 12816S Lot_ID: 1 Source: Cell Signaling Technology Target Name: SSU72-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SSU72 is not avaliable on ENCORE database.

Proteins bound to RNA

SSU72 RNA is bound by 37 proteins.

eCLIP assay for SSU72 is not avaliable on ENCORE database.

37 proteins are bound to SSU72 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	1477310	1477395	-	3'-UTR,intron-Distal	4.31399	6.03373	HepG2	LARP4
chr1	1477283	1477378	-	3'-UTR,intron-Distal	3.73249	9.66665	K562	APOBEC3C
chr1	1477070	1477154	-	3'-UTR,intron-Distal	3.59392	7.56242	K562	PUM2
chr1	1477299	1477441	-	3'-UTR,intron-Distal	3.65011	29.14549	K562	PUM2
chr1	1498115	1498168	-	3'-UTR,intron-Distal	5.03510	31.92487	K562	NONO
chr1	1477322	1477372	-	3'-UTR,intron-Distal	3.80179	13.00883	K562	TIA1
chr1	1477200	1477263	-	3'-UTR,intron-Distal	6.15581	43.68467	K562	IGF2BP1
chr1	1498239	1498292	-	3'-UTR,intron-Distal	3.11059	6.37538	K562	NONO
chr1	1477306	1477379	-	3'-UTR,intron-Distal	3.69081	8.07401	K562	U2AF2
chr1	1477229	1477250	-	3'-UTR,intron-Distal	4.53953	11.52455	K562	PABPC4
chr1	1477372	1477389	-	3'-UTR,intron-Distal	3.29191	3.80983	K562	TIA1
chr1	1477320	1477393	-	3'-UTR,intron-Distal	4.52677	7.36168	HepG2	SUB1
chr1	1477297	1477403	-	3'-UTR,intron-Distal	3.78816	16.25335	K562	DDX55
chr1	1477289	1477330	-	3'-UTR,intron-Distal	6.70790	44.33447	K562	PABPC4
chr1	1477422	1477471	-	3'-UTR,CDS,intron-Distal	3.27322	4.65702	K562	GEMIN5
chr1	1477078	1477118	-	3'-UTR,intron-Distal	3.82254	15.07781	K562	IGF2BP2
chr1	1477281	1477379	-	3'-UTR,intron-Distal	5.17675	30.28443	K562	IGF2BP1
chr1	1497771	1497791	-	3'-UTR,intron-Distal	4.16316	4.58989	K562	NONO
chr1	1498868	1498919	-	3'-UTR,intron-Distal	3.19983	3.48322	HepG2	UPF1
chr1	1477322	1477385	-	3'-UTR,intron-Distal	3.16680	4.71369	K562	U2AF1
chr1	1499713	1499791	-	3'-UTR,intron-Distal	3.31994	4.01428	K562	TARDBP
chr1	1498082	1498115	-	3'-UTR,intron-Distal	4.22704	7.24988	K562	NONO
chr1	1477330	1477379	-	3'-UTR,intron-Distal	5.41571	400.00000	K562	PABPC4
chr1	1477085	1477164	-	3'-UTR,intron-Distal	4.56629	17.48589	K562	IGF2BP1
chr1	1498863	1498924	-	3'-UTR,intron-Distal	3.92585	4.20638	K562	HNRNPC
chr1	1477110	1477209	-	3'-UTR,intron-Distal	3.55575	3.60582	K562	PCBP1
chr1	1477401	1477544	-	3'-UTR,CDS,intron-Distal	4.24256	7.27605	HepG2	GRWD1
chr1	1477100	1477204	-	3'-UTR,intron-Distal	3.09682	16.93338	K562	PABPC4
chr1	1477164	1477197	-	3'-UTR,intron-Distal	6.22540	21.73083	K562	IGF2BP1
chr1	1509959	1510011	-	5'-UTR,intron-Distal,intron-Proximal	3.44567	6.31840	K562	LIN28B
chr1	1509903	1509954	-	5'-UTR,CDS,intron-Distal	4.51907	21.81736	HepG2	DDX3X
chr1	1509961	1510001	-	5'-UTR,intron-Distal,intron-Proximal	3.29452	5.82217	HepG2	DDX3X
chr1	1509960	1510009	-	5'-UTR,intron-Distal,intron-Proximal	4.48324	10.51564	K562	GEMIN5
chr1	1509915	1509942	-	5'-UTR,CDS,intron-Distal	3.27033	11.60262	K562	LIN28B
chr1	1509873	1509958	-	5'-UTR,CDS,intron-Distal	4.33227	7.70265	K562	RBM15
chr1	1510085	1510194	-	5'-UTR,intron-Distal	4.29504	15.91999	K562	DDX3X
chr1	1510037	1510095	-	5'-UTR,intron-Distal,intron-Proximal	3.91328	10.03627	K562	GEMIN5
chr1	1510045	1510220	-	5'-UTR,intron-Distal,intron-Proximal	6.21097	400.00000	HepG2	DDX3X
chr1	1509962	1510012	-	5'-UTR,intron-Distal,intron-Proximal	3.49002	4.98411	K562	RBM15
chr1	1509942	1509953	-	5'-UTR,intron-Distal	3.65896	10.87979	K562	LIN28B
chr1	1510160	1510223	-	5'-UTR,intron-Distal	4.81310	3.80483	K562	DDX52
chr1	1510008	1510056	-	5'-UTR,intron-Distal,intron-Proximal	3.49460	6.75245	K562	NONO
chr1	1509898	1509960	-	5'-UTR,CDS,intron-Distal	4.24448	10.33220	K562	GEMIN5
chr1	1509882	1509963	-	5'-UTR,CDS,intron-Distal	4.24459	40.63127	K562	DDX3X
chr1	1479277	1479314	-	CDS,intron-Distal	3.48056	6.61971	K562	YBX3
chr1	1480339	1480383	-	CDS,intron-Distal,intron-Proximal	4.11730	6.24329	K562	IGF2BP1
chr1	1500209	1500282	-	CDS,intron-Distal	3.44809	5.22707	K562	GRWD1
chr1	1477544	1477547	-	CDS,intron-Distal	3.45729	10.68112	K562	YBX3
chr1	1500155	1500209	-	CDS,intron-Distal	3.36654	7.02736	K562	PABPC4
chr1	1480242	1480361	-	CDS,intron-Distal,intron-Proximal	3.28786	4.34695	HepG2	BCLAF1
chr1	1500274	1500296	-	CDS,intron-Distal	3.17665	10.54772	K562	DDX3X
chr1	1500051	1500148	-	CDS,intron-Distal,intron-Proximal	3.02358	4.59262	K562	RBM15
chr1	1479248	1479277	-	CDS,intron-Distal,intron-Proximal	4.31677	20.87348	K562	YBX3
chr1	1509856	1509882	-	CDS,intron-Distal	4.23644	17.15403	K562	DDX3X
chr1	1479321	1479368	-	CDS,intron-Distal,intron-Proximal	3.90635	3.12746	HepG2	GRWD1
chr1	1500151	1500209	-	CDS,intron-Distal,intron-Proximal	4.68914	6.94558	K562	GRWD1
chr1	1479247	1479314	-	CDS,intron-Distal,intron-Proximal	3.70759	3.60954	K562	PUM1
chr1	1500280	1500354	-	CDS,intron-Distal,intron-Proximal	5.21559	6.40247	K562	SF3B4
chr1	1500056	1500112	-	CDS,intron-Distal,intron-Proximal	3.74461	6.09306	K562	NONO
chr1	1477508	1477549	-	CDS,intron-Distal	3.52161	3.60954	K562	PUM1
chr1	1500216	1500312	-	CDS,intron-Distal,intron-Proximal	3.69129	7.03984	K562	U2AF2
chr1	1479249	1479292	-	CDS,intron-Distal	3.80201	8.84200	K562	PABPC4
chr1	1480305	1480383	-	CDS,intron-Distal,intron-Proximal	3.76216	5.36496	K562	ZNF800
chr1	1500218	1500287	-	CDS,intron-Distal	3.76472	4.72321	K562	SRSF1
chr1	1500150	1500209	-	CDS,intron-Distal,intron-Proximal	4.18368	6.24329	K562	IGF2BP1
chr1	1502433	1502484	-	intron-Distal	5.17282	8.23608	HepG2	HNRNPM
chr1	1489494	1489547	-	intron-Distal	3.48655	4.48585	K562	NONO
chr1	1487296	1487374	-	intron-Distal	3.35967	5.41408	K562	NONO
chr1	1500951	1501005	-	intron-Distal	4.13341	6.54942	K562	NONO
chr1	1502686	1502744	-	intron-Distal	3.06216	4.76743	K562	HNRNPM
chr1	1509549	1509608	-	intron-Distal	4.18293	5.16186	K562	NONO
chr1	1490185	1490243	-	intron-Distal	5.12129	7.10563	K562	NONO
chr1	1503330	1503386	-	intron-Distal	5.25594	9.74359	K562	HNRNPM
chr1	1509673	1509730	-	intron-Distal	5.29589	6.16396	K562	NONO
chr1	1496903	1496974	-	intron-Distal	3.77262	7.90586	K562	NONO
chr1	1490166	1490262	-	intron-Distal	3.05868	6.35020	HepG2	CSTF2T
chr1	1502919	1502979	-	intron-Distal	3.18097	3.63437	HepG2	HNRNPM
chr1	1490496	1490549	-	intron-Distal	4.92842	5.91582	K562	NONO
chr1	1483139	1483227	-	intron-Distal	5.01952	5.91582	K562	NONO
chr1	1502695	1502747	-	intron-Distal	4.54015	3.97018	HepG2	HNRNPM
chr1	1489968	1490027	-	intron-Distal	4.12064	6.54942	K562	NONO
chr1	1489547	1489583	-	intron-Distal	3.33712	4.01575	K562	NONO
chr1	1502918	1502977	-	intron-Distal	4.13095	7.02931	K562	HNRNPM
chr1	1477821	1478014	-	intron-Distal	3.38070	3.10628	K562	HNRNPM
chr1	1482965	1483054	-	intron-Distal	3.47718	4.85046	K562	NONO
chr1	1490132	1490179	-	intron-Distal	4.48188	3.76710	K562	NONO
chr1	1496904	1496977	-	intron-Distal	3.57186	5.29044	K562	CSTF2T
chr1	1497224	1497333	-	intron-Distal	3.33454	4.48257	K562	FUS
chr1	1500313	1500392	-	intron-Distal,intron-Proximal	4.09583	3.90026	K562	KHSRP
chr1	1490330	1490385	-	intron-Distal	4.56162	3.98553	K562	NONO
chr1	1503333	1503392	-	intron-Distal	4.26593	8.19743	HepG2	HNRNPM
chr1	1497208	1497329	-	intron-Distal	3.97248	5.75592	K562	DROSHA
chr1	1489641	1489709	-	intron-Distal	3.09263	3.54602	K562	TIA1
chr1	1489710	1489748	-	intron-Distal	4.32558	3.98553	K562	NONO
chr1	1501286	1501313	-	intron-Distal	3.03889	3.38183	K562	NONO
chr1	1509627	1509673	-	intron-Distal	4.74244	4.48497	K562	NONO
chr1	1500956	1501113	-	intron-Distal	4.67741	5.57532	K562	HNRNPM
chr1	1489626	1489686	-	intron-Distal	4.88689	6.64417	K562	NONO
chr1	1490997	1491024	-	intron-Distal	4.10765	3.76710	K562	NONO
chr1	1496910	1496998	-	intron-Distal	3.32585	4.50064	HepG2	SFPQ
chr1	1496915	1497003	-	intron-Distal	4.63829	5.64992	HepG2	NKRF
chr1	1487573	1487657	-	intron-Distal	3.28845	3.89711	K562	NONO
chr1	1501093	1501145	-	intron-Distal	3.14041	5.20317	K562	NONO
chr1	1501005	1501053	-	intron-Distal	3.05287	3.87436	K562	NONO
chr1	1487864	1487946	-	intron-Distal	4.50945	5.42636	K562	NONO
chr1	1509506	1509548	-	intron-Distal	4.78367	6.64417	K562	NONO
chr1	1489748	1489876	-	intron-Distal	4.39464	16.87930	K562	NONO
chr1	1483257	1483308	-	intron-Distal	4.62769	5.19780	K562	NONO
chr1	1492089	1492151	-	intron-Distal	3.35631	3.57996	HepG2	XPO5
chr1	1500886	1500951	-	intron-Distal	3.69819	6.75245	K562	NONO
chr1	1497254	1497315	-	intron-Distal	4.26157	4.71107	K562	CSTF2T
chr1	1496903	1496983	-	intron-Distal	3.24870	4.40213	K562	EWSR1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for SSU72 is not avaliable on ENCORE database.

Summary
DE Affected by

Diffrential Expression

The Knockdown/knockout assay for SSU72 is not available on ENCORE database.
52 RBPs can affect the levels of SSU72.

The Knockdown/knockout RNA-Seq assay for SSU72 is not available on ENCORE database.

52 RBPs can affect the gene expression of SSU72 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SSU72	ENSG00000160075.10	1280.23510	1069.75240	0.25900	2.81010	2.19870	HepG2	ACO1
SSU72	ENSG00000160075.10	2146.33970	1604.69230	0.41950	2.95310	2.40570	HepG2	AKAP1
SSU72	ENSG00000160075.10	973.57320	1327.72910	-0.44760	3.52220	2.63780	HepG2	ASCC1
SSU72	ENSG00000160075.10	2024.21060	1667.90170	0.27920	2.16890	1.63410	HepG2	BOP1
SSU72	ENSG00000160075.10	1247.45410	1069.42210	0.22210	2.28260	1.66940	HepG2	CKAP4
SSU72	ENSG00000160075.10	1685.02600	1445.67700	0.22090	2.16560	1.58580	HepG2	CELF1
SSU72	ENSG00000160075.10	577.51250	829.43970	-0.52230	3.33320	2.10830	HepG2	AGO1
SSU72	ENSG00000160075.10	761.18330	1045.25240	-0.45750	4.42670	3.37460	HepG2	EWSR1
SSU72	ENSG00000160075.10	628.15620	867.82620	-0.46630	3.06780	1.73350	HepG2	FKBP4
SSU72	ENSG00000160075.10	969.12710	1735.85850	-0.84090	10.25520	9.07690	HepG2	GPKOW
SSU72	ENSG00000160075.10	1301.52690	1656.55560	-0.34800	2.50900	1.90510	HepG2	HNRNPLL
SSU72	ENSG00000160075.10	950.11350	1163.12790	-0.29180	2.23150	1.37690	HepG2	HNRNPM
SSU72	ENSG00000160075.10	1418.53370	989.76720	0.51910	10.97270	9.61700	HepG2	ILF2
SSU72	ENSG00000160075.10	1041.20570	1689.32290	-0.69820	5.01860	3.68880	HepG2	MTPAP
SSU72	ENSG00000160075.10	1127.19930	1468.80400	-0.38190	3.09840	2.30790	HepG2	NSUN2
SSU72	ENSG00000160075.10	928.34670	1297.79500	-0.48330	3.83110	2.99300	HepG2	PABPC4
SSU72	ENSG00000160075.10	1260.70300	1560.76610	-0.30800	2.78790	2.11440	HepG2	PUM2
SSU72	ENSG00000160075.10	1165.95080	1455.06440	-0.31960	3.14100	2.48190	HepG2	QKI
SSU72	ENSG00000160075.10	1620.48730	1052.17940	0.62290	3.49390	2.70400	HepG2	RAVER1
SSU72	ENSG00000160075.10	1009.54290	1320.56080	-0.38740	3.64090	2.87400	HepG2	RBM25
SSU72	ENSG00000160075.10	1277.23110	1495.20170	-0.22730	2.17920	1.68720	HepG2	NELFE
SSU72	ENSG00000160075.10	1187.74320	1392.57030	-0.22950	2.16890	1.61420	HepG2	RECQL
SSU72	ENSG00000160075.10	1266.75710	1006.25800	0.33200	4.61650	3.82100	HepG2	SMN1
SSU72	ENSG00000160075.10	1333.17720	1824.44190	-0.45260	2.41820	1.69000	HepG2	SNRNP70
SSU72	ENSG00000160075.10	899.77750	1187.79770	-0.40060	5.56540	4.82990	HepG2	SRSF9
SSU72	ENSG00000160075.10	919.24420	1312.30980	-0.51360	7.10140	6.27500	HepG2	TAF15
SSU72	ENSG00000160075.10	880.39200	1205.84370	-0.45380	4.93900	3.83180	HepG2	TIA1
SSU72	ENSG00000160075.10	1303.51520	949.95890	0.45640	7.02780	6.20010	HepG2	TRIM56
SSU72	ENSG00000160075.10	873.75940	613.09390	0.51100	3.79240	2.90390	HepG2	UCHL5
SSU72	ENSG00000160075.10	1895.44100	1383.74980	0.45390	8.31080	7.36250	HepG2	UTP3
SSU72	ENSG00000160075.10	4075.61510	3301.87180	0.30360	2.76170	2.17420	K562	AQR
SSU72	ENSG00000160075.10	4528.57070	3413.05840	0.40790	8.84800	7.76550	K562	DDX47
SSU72	ENSG00000160075.10	1771.52730	1259.25520	0.49230	7.69690	6.37540	K562	EIF3G
SSU72	ENSG00000160075.10	3970.95920	2727.86630	0.54160	7.28760	5.84950	K562	FIP1L1
SSU72	ENSG00000160075.10	2525.94670	1720.54720	0.55390	11.57320	10.42300	K562	FXR1
SSU72	ENSG00000160075.10	777.82370	1142.20890	-0.55430	3.85400	2.98840	K562	G3BP2
SSU72	ENSG00000160075.10	1303.39710	1811.63340	-0.47500	4.14540	2.37020	K562	GEMIN5
SSU72	ENSG00000160075.10	2213.95020	1539.43250	0.52410	5.44330	3.65450	K562	HNRNPK
SSU72	ENSG00000160075.10	2249.38860	1619.93130	0.47350	6.07010	4.80660	K562	MAGOH
SSU72	ENSG00000160075.10	1994.39000	1616.62600	0.30290	2.80270	1.87390	K562	MATR3
SSU72	ENSG00000160075.10	1822.69400	1441.31500	0.33860	3.03260	2.00940	K562	PCBP2
SSU72	ENSG00000160075.10	2268.74500	3029.99330	-0.41740	3.58550	2.63820	K562	PCBP3
SSU72	ENSG00000160075.10	1689.35890	2324.02480	-0.46010	6.31530	5.10940	K562	POLR2G
SSU72	ENSG00000160075.10	4038.99970	3096.59970	0.38320	3.73400	2.75910	K562	PPIG
SSU72	ENSG00000160075.10	2779.61040	1758.41110	0.66050	9.07820	7.71850	K562	PRPF8
SSU72	ENSG00000160075.10	2779.82480	1573.87400	0.82060	18.04070	16.41780	K562	PTBP1
SSU72	ENSG00000160075.10	5311.36480	4291.54510	0.30750	3.27110	2.38520	K562	PUF60
SSU72	ENSG00000160075.10	2079.97880	1509.08920	0.46280	4.98360	3.81600	K562	RBM22
SSU72	ENSG00000160075.10	2385.40290	2915.95300	-0.28970	5.30160	4.05600	K562	SRPK2
SSU72	ENSG00000160075.10	1984.83340	1542.93520	0.36320	3.86730	3.03720	K562	SRSF1
SSU72	ENSG00000160075.10	2803.40470	2331.17270	0.26600	2.60700	1.81310	K562	SYNCRIP
SSU72	ENSG00000160075.10	2237.30440	1561.52100	0.51870	5.67270	4.63870	K562	TARDBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SSU72

General Information

Functions

Localization

Domains (AlphaFold: SSU72)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SSU72 is not avaliable on ENCORE database.

37 proteins are bound to SSU72 RNA:

eCLIP assay for SSU72 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SSU72 is not available on ENCORE database.

52 RBPs can affect the gene expression of SSU72 :

The Knockdown/knockout RNA-Seq assay for SSU72 is not available on ENCORE database.

No RBPs affect the alternative splcing events of SSU72 on ENCORE database.

The Knockdown/knockout RNA-Seq assay for SSU72 is not avaliable on ENCORE database.