PPP2R1A

General Information

Gene Name       : PPP2R1A
Gene ID             : ENSG00000105568.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PPP2R1A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPP2R1AENSG00000105568.1778.12121.1599.64ENCSR000AEF
HepG2PPP2R1AENSG00000105568.17123.9185.57104.74ENCSR985KAT
K562PPP2R1AENSG00000105568.17110.80101.81106.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPP2R1A is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPP2R1A RNA is bound by 24 proteins.  







eCLIP assay for PPP2R1A is not avaliable on ENCORE database.





24 proteins are bound to PPP2R1A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr195271464052714715+3'-UTR,5'-UTR,CDS3.988075.68852HepG2RPS3
chr195272915452729212+3'-UTR,intron-Proximal3.617506.59423HepG2SF3B4
chr195272923252729282+3'-UTR3.970784.02740K562PCBP1
chr195272929752729353+3'-UTR3.387059.93776K562PABPC4
chr195272939152729463+3'-UTR6.5210324.21988HepG2UPF1
chr195272941152729469+3'-UTR3.685335.93417K562PABPC4
chr195271457952714628+3'-UTR,5'-UTR,CDS4.487695.09669K562FMR1
chr195270922152709277+3'-UTR,5'-UTR,CDS,intron-Distal3.790499.58474HepG2PPIG
chr195272929252729391+3'-UTR5.1010213.56429HepG2UPF1
chr195270921552709270+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.308005.64870K562DDX24
chr195272931752729451+3'-UTR5.6777115.88042K562PCBP1
chr195272918952729245+3'-UTR,CDS,intron-Proximal4.422564.92499HepG2AQR
chr195270927352709295+3'-UTR,5'-UTR,CDS,intron-Distal3.205057.54844K562YBX3
chr195272946352729532+3'-UTR4.483459.01880HepG2UPF1
chr195270526552705335+3'-UTR,5'-UTR,CDS,intron-Proximal5.350157.02967HepG2PRPF8
chr195270927052709326+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.285803.11409K562DDX24
chr195271445352714563+3'-UTR,5'-UTR,CDS,intron-Proximal4.174658.76959K562SF3B4
chr195272959552729630+3'-UTR3.096993.01032HepG2LARP4
chr195272945952729554+3'-UTR3.3929411.08196K562UPF1
chr195270921652709273+3'-UTR,5'-UTR,CDS,intron-Distal3.035229.38711K562YBX3
chr195272930152729421+3'-UTR3.146136.73008HepG2AKAP1
chr195270924952709414+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.2679011.69650HepG2PRPF8
chr195272939352729451+3'-UTR3.450035.27408HepG2LARP4
chr195272923452729395+3'-UTR3.365274.92170K562PHF6
chr195272942052729511+3'-UTR4.176677.50821HepG2G3BP1
chr195272959152729647+3'-UTR3.4713212.14953K562PABPC4
chr195271451152714552+3'-UTR,5'-UTR,CDS,intron-Proximal4.861287.12026HepG2G3BP1
chr195272959652729640+3'-UTR3.406653.80983K562TIA1
chr195272942152729565+3'-UTR3.954857.15385HepG2AKAP1
chr195270931352709374+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.614675.70278K562AQR
chr195270922152709310+3'-UTR,5'-UTR,CDS,intron-Distal4.905716.65038K562METAP2
chr195272959052729645+3'-UTR3.9839416.49785K562UPF1
chr195269330652693428+5'-UTR,CDS,intron-Proximal3.421356.39699K562DDX3X
chr195269340552693502+5'-UTR,CDS,intron-Proximal4.0417310.86325HepG2PRPF8
chr195271474452714791+5'-UTR,CDS,intron-Proximal5.060865.69951K562AQR
chr195271594452716055+5'-UTR,CDS4.519507.57065K562FXR2
chr195271620352716250+CDS,intron-Proximal3.935774.78507K562FXR2
chr195271980452719917+CDS,intron-Proximal5.3187018.41857K562METAP2
chr195271607952716168+CDS,intron-Proximal4.632734.28193HepG2AQR
chr195272303852723085+CDS3.345075.74594HepG2G3BP1
chr195272294352723028+CDS,intron-Proximal4.2018212.65787HepG2G3BP1
chr195271627252716342+CDS4.741555.27247HepG2RPS3
chr195271630852716367+CDS,intron-Proximal3.935465.24452HepG2PPIG
chr195272540452725447+CDS4.382674.54113K562IGF2BP2
chr195272428152724354+CDS4.6006612.02487HepG2G3BP1
chr195272896952729018+CDS,intron-Proximal4.012358.29368HepG2G3BP1
chr195271979752719899+CDS3.6279013.03934HepG2YBX3
chr195269344452693530+CDS,intron-Distal,intron-Proximal3.060643.00054HepG2PRPF4
chr195272308552723118+CDS,intron-Proximal4.205183.82843HepG2PPIG
chr195272294352723033+CDS,intron-Proximal5.4409010.37163K562METAP2
chr195271903152719142+CDS,intron-Proximal3.6235512.97200HepG2G3BP1
chr195271991152719916+CDS3.063546.45876K562YBX3
chr195271977952719804+CDS,intron-Proximal4.744755.67147K562METAP2
chr195271632952716362+CDS3.763415.73518HepG2G3BP1
chr195271990252719915+CDS3.514454.22242HepG2G3BP1
chr195272303252723081+CDS5.164515.96949K562FMR1
chr195272343752723540+CDS,intron-Proximal5.253247.70650HepG2PRPF8
chr195271980152719828+CDS4.1035517.79648K562YBX3
chr195272345952723502+CDS4.252228.03104HepG2G3BP1
chr195272297152723092+CDS4.178737.33300K562FXR2
chr195271620752716272+CDS,intron-Proximal4.006815.18795HepG2RPS3
chr195271978152719801+CDS,intron-Proximal3.5825711.05259K562YBX3
chr195271907652719138+CDS3.460775.74131HepG2PPIG
chr195271932252719327+CDS3.424829.54031K562YBX3
chr195272903052729047+CDS3.8138510.11050K562YBX3
chr195271985852719862+CDS4.1168123.20273K562YBX3
chr195271982852719841+CDS6.1101142.75718K562YBX3
chr195271929152719328+CDS,intron-Proximal4.687184.49458K562METAP2
chr195272897652729058+CDS3.632457.10944HepG2PPIG
chr195271981752719902+CDS3.008157.39452HepG2G3BP1
chr195269345752693513+CDS,intron-Proximal3.073873.49516HepG2CSTF2T
chr195272423152724274+CDS,intron-Proximal3.384188.25459HepG2G3BP1
chr195272544552725494+CDS5.4771211.65738HepG2G3BP1
chr195271986252719880+CDS3.6867623.14765K562YBX3
chr195271984352719858+CDS4.6339238.91607K562YBX3
chr195271988052719911+CDS3.2364420.43061K562YBX3
chr195271620352716251+CDS,intron-Proximal3.399287.36645HepG2PPIG
chr195272298852723036+CDS4.354964.67689HepG2PPIG
chr195272900752729028+CDS3.496297.18470K562YBX3
chr195271926952719328+CDS,intron-Proximal4.683478.13934K562RPS3
chr195271625052716313+CDS4.5734411.49757HepG2G3BP1
chr195272344152723459+CDS,intron-Proximal4.692526.00552HepG2G3BP1
chr195271634452716423+CDS,intron-Proximal3.548066.65114HepG2PRPF8
chr195271605052716086+CDS3.493806.97264K562YBX3
chr195270932552709440+intron-Distal,intron-Proximal5.064157.61488HepG2EFTUD2
chr195272000752720073+intron-Distal,intron-Proximal4.135683.12843K562PRPF8
chr195270933252709393+intron-Distal,intron-Proximal3.846934.34418HepG2RBM22
chr195272318052723259+intron-Distal,intron-Proximal5.932638.50915HepG2EFTUD2
chr195272320552723271+intron-Distal,intron-Proximal4.100584.36481K562EFTUD2
chr195271917852719249+intron-Proximal5.554027.84927K562EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPP2R1A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPP2R1A is not available on ENCORE database.

  • 78 RBPs can affect the levels of PPP2R1A.  








The Knockdown/knockout RNA-Seq assay for PPP2R1A is not available on ENCORE database.





78 RBPs can affect the gene expression of PPP2R1A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPP2R1AENSG00000105568.134415.908102752.666200.6818016.6918015.46550HepG2ACO1
PPP2R1AENSG00000105568.135678.152104134.843400.457501.777301.34130HepG2AKAP1
PPP2R1AENSG00000105568.133537.902602282.996300.631903.012501.92890HepG2AKAP8
PPP2R1AENSG00000105568.133914.758902765.237000.501406.220305.11440HepG2AKAP8L
PPP2R1AENSG00000105568.135177.410204476.863100.209602.947302.24190HepG2AUH
PPP2R1AENSG00000105568.131783.120701100.378800.696309.751608.71500HepG2BOP1
PPP2R1AENSG00000105568.132286.778703250.21250-0.507202.261301.55810HepG2CIRBP
PPP2R1AENSG00000105568.133367.394402751.632700.291205.359804.49000HepG2CKAP4
PPP2R1AENSG00000105568.134140.622202047.891001.0156010.150508.71850HepG2CNOT7
PPP2R1AENSG00000105568.133968.659002871.447600.466806.875905.94920HepG2CELF1
PPP2R1AENSG00000105568.133654.963103087.017200.243504.131703.25460HepG2DAZAP1
PPP2R1AENSG00000105568.133209.835902545.621800.334404.669603.62350HepG2DDX19B
PPP2R1AENSG00000105568.131431.148002030.18190-0.504406.031404.68830HepG2DDX24
PPP2R1AENSG00000105568.132045.825802633.44310-0.364302.699702.02950HepG2DKC1
PPP2R1AENSG00000105568.132401.495401698.718000.499402.595001.69940HepG2EEF2
PPP2R1AENSG00000105568.132415.330403045.95750-0.334704.416803.40140HepG2EIF4G1
PPP2R1AENSG00000105568.133738.589902689.460300.475106.686305.39230HepG2EWSR1
PPP2R1AENSG00000105568.134321.408803382.788100.353201.915901.35770HepG2G3BP1
PPP2R1AENSG00000105568.131929.201201227.517800.652206.281004.93330HepG2GEMIN5
PPP2R1AENSG00000105568.132902.670501977.875000.553307.532806.43450HepG2HNRNPC
PPP2R1AENSG00000105568.133746.588702811.886500.4139011.7968010.49040HepG2HNRNPL
PPP2R1AENSG00000105568.132371.870601964.804400.271501.802901.30440HepG2HNRNPU
PPP2R1AENSG00000105568.133230.663502516.011300.360604.126102.89240HepG2KIF1C
PPP2R1AENSG00000105568.133912.938003061.106300.354104.652703.66380HepG2NOL12
PPP2R1AENSG00000105568.13739.89040968.99910-0.389202.682401.94560HepG2NSUN2
PPP2R1AENSG00000105568.131935.653503596.34840-0.8937036.0810034.31600HepG2PCBP1
PPP2R1AENSG00000105568.131468.027202015.19040-0.457007.977706.75080HepG2PRPF4
PPP2R1AENSG00000105568.132594.014301634.066000.666603.586302.67940HepG2PRPF8
PPP2R1AENSG00000105568.134374.448902922.230800.5819010.069809.03040HepG2PUF60
PPP2R1AENSG00000105568.133771.610703102.237200.281806.078505.26990HepG2PUM1
PPP2R1AENSG00000105568.133615.115102803.705400.366607.571506.63570HepG2PUS1
PPP2R1AENSG00000105568.132915.516301943.462400.585003.315902.54700HepG2RAVER1
PPP2R1AENSG00000105568.135489.297104296.180100.353505.712605.03610HepG2RBM22
PPP2R1AENSG00000105568.133187.759903793.19460-0.250902.977602.34090HepG2RECQL
PPP2R1AENSG00000105568.133707.856302282.141200.700103.864903.06150HepG2SF3A3
PPP2R1AENSG00000105568.133259.308203809.86880-0.225203.062502.44420HepG2SF3B4
PPP2R1AENSG00000105568.133575.730903976.73530-0.153301.735101.33620HepG2SRSF1
PPP2R1AENSG00000105568.133492.584802885.469300.275404.230003.48500HepG2SRSF5
PPP2R1AENSG00000105568.132127.859003235.33510-0.6045018.3029017.11210HepG2SRSF9
PPP2R1AENSG00000105568.133609.256404212.92090-0.223103.459902.90100HepG2SSB
PPP2R1AENSG00000105568.134024.079203281.409100.294206.037205.18260HepG2SUCLG1
PPP2R1AENSG00000105568.132121.726203574.60310-0.7525016.4541015.25210HepG2TAF15
PPP2R1AENSG00000105568.132609.631603284.40520-0.331803.717202.75470HepG2TIA1
PPP2R1AENSG00000105568.132956.623602023.916100.5467015.1525013.77060HepG2UPF1
PPP2R1AENSG00000105568.132324.118101988.696200.224803.202802.48940HepG2ZC3H8
PPP2R1AENSG00000105568.136482.994803530.954700.8765042.9583040.76960K562AGGF1
PPP2R1AENSG00000105568.133165.576102532.824700.321603.294701.62700K562AKAP1
PPP2R1AENSG00000105568.135564.445503879.961700.520107.421705.60220K562AKAP8
PPP2R1AENSG00000105568.136162.731003674.112600.746104.061103.26870K562AKAP8L
PPP2R1AENSG00000105568.133826.622704889.76090-0.353703.314802.68420K562AQR
PPP2R1AENSG00000105568.131393.524801888.28500-0.438303.990802.67720K562CCAR1
PPP2R1AENSG00000105568.135667.154806758.67780-0.254103.136302.09990K562CELF1
PPP2R1AENSG00000105568.132457.583003210.69050-0.385607.276606.28860K562DDX47
PPP2R1AENSG00000105568.131534.083602113.91140-0.462504.350402.62270K562DHX30
PPP2R1AENSG00000105568.134901.871403953.645000.310004.891203.67380K562DKC1
PPP2R1AENSG00000105568.131344.259202030.55390-0.595107.364705.25630K562DNAJC21
PPP2R1AENSG00000105568.131390.394802152.38820-0.630403.453701.47340K562DNAJC2
PPP2R1AENSG00000105568.133408.142702516.222100.437602.659401.40650K562EEF2
PPP2R1AENSG00000105568.131717.799601255.919900.451706.344705.15680K562EIF3G
PPP2R1AENSG00000105568.134799.525005496.38900-0.195602.476201.58380K562EIF4G2
PPP2R1AENSG00000105568.133235.568002340.787100.466903.670202.15250K562EWSR1
PPP2R1AENSG00000105568.133480.735202243.801100.633304.996303.83370K562FIP1L1
PPP2R1AENSG00000105568.13503.191001309.61910-1.380007.865006.54530K562G3BP2
PPP2R1AENSG00000105568.133571.290102141.586900.737704.675503.20000K562IGF2BP2
PPP2R1AENSG00000105568.133244.685002177.508700.575302.587101.44720K562IGF2BP3
PPP2R1AENSG00000105568.134847.211403899.172300.313903.178002.28910K562KIF1C
PPP2R1AENSG00000105568.135056.813703732.450700.438004.411202.96300K562MAK16
PPP2R1AENSG00000105568.136039.288404368.054900.467307.067905.48870K562MBNL1
PPP2R1AENSG00000105568.134094.280503061.688400.419202.919002.00990K562NAA15
PPP2R1AENSG00000105568.134286.589402004.847601.096207.740405.79730K562PABPN1
PPP2R1AENSG00000105568.132615.774803480.48330-0.412003.536202.59570K562PCBP3
PPP2R1AENSG00000105568.134668.547505647.73440-0.274703.372501.78900K562PNPT1
PPP2R1AENSG00000105568.132165.235802669.67500-0.302103.231602.36190K562POLR2G
PPP2R1AENSG00000105568.134139.634902383.415400.796402.740301.31820K562PPP1R8
PPP2R1AENSG00000105568.132812.205902184.999200.364002.038501.45210K562PTBP1
PPP2R1AENSG00000105568.134895.206105996.91530-0.292902.374601.61970K562PUF60
PPP2R1AENSG00000105568.134838.743806379.08560-0.398706.466904.77890K562PUM1
PPP2R1AENSG00000105568.135028.145006249.80680-0.313805.350303.99540K562PUM2
PPP2R1AENSG00000105568.136713.425803643.753700.881506.288005.50850K562PUS1
PPP2R1AENSG00000105568.136014.116003550.254100.7603023.2932021.50350K562RBM15
PPP2R1AENSG00000105568.133548.240301833.410700.952504.481202.83720K562SF1
PPP2R1AENSG00000105568.133978.070102235.024400.831703.653102.06850K562SFPQ
PPP2R1AENSG00000105568.131593.117902079.79670-0.384603.403401.98890K562SLBP
PPP2R1AENSG00000105568.132520.442101856.839200.440702.860501.81330K562SRFBP1
PPP2R1AENSG00000105568.132992.763902023.719900.564402.227501.30590K562SRSF5
PPP2R1AENSG00000105568.132422.348203038.76560-0.327104.011602.17720K562SRSF9
PPP2R1AENSG00000105568.133032.613202167.625800.484302.406501.74440K562TARDBP
PPP2R1AENSG00000105568.133075.089202091.041800.556303.282202.38020K562TIA1
PPP2R1AENSG00000105568.133107.143002053.031900.597704.072302.70450K562TRA2A
PPP2R1AENSG00000105568.13891.650701310.13900-0.555203.145902.29030K562U2AF2
PPP2R1AENSG00000105568.133339.121602787.186300.260602.376301.56320K562WDR3
PPP2R1AENSG00000105568.132453.389002898.30840-0.240403.727402.75520K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPP2R1A is not available on ENCORE database.






No RBPs affect the alternative splcing events of PPP2R1A on ENCORE database.





The Knockdown/knockout RNA-Seq assay for PPP2R1A is not avaliable on ENCORE database.