PPM1K

General Information

Gene Name       : PPM1K
Gene ID             : ENSG00000163644.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PPM1K)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PPM1KENSG00000163644.1424.5321.9023.21ENCSR000AEF
HepG2PPM1KENSG00000163644.144.424.834.62ENCSR985KAT
K562PPM1KENSG00000163644.145.955.645.79ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PPM1K is not avaliable on ENCORE database.



Proteins bound to RNA
  • PPM1K RNA is bound by 4 proteins.  







eCLIP assay for PPM1K is not avaliable on ENCORE database.





4 proteins are bound to PPM1K RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr48919821889198308-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.953183.02181K562PRPF8
chr48920501489205138-5'-UTR,intron-Distal,intron-Proximal3.043173.23466HepG2CSTF2T
chr48919931389199372-CDS,intron-Distal,intron-Proximal4.395935.87734K562LIN28B
chr48918756489187622-intron-Distal3.577705.91893K562AGGF1
chr48918791889188026-intron-Distal4.5183813.20432K562AGGF1
chr48920544789205540-intron-Distal,intron-Proximal3.639025.29044K562CSTF2T
chr48918828689188359-intron-Distal5.036195.63362K562AGGF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PPM1K is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PPM1K is not available on ENCORE database.

  • 90 RBPs can affect the levels of PPM1K.  








The Knockdown/knockout RNA-Seq assay for PPM1K is not available on ENCORE database.





90 RBPs can affect the gene expression of PPM1K :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PPM1KENSG00000163644.10176.09510351.66740-0.9979010.355208.98530HepG2AKAP8L
PPM1KENSG00000163644.10605.65510477.777500.342102.443601.79080HepG2AUH
PPM1KENSG00000163644.10177.95320343.22540-0.947705.389704.07010HepG2BCCIP
PPM1KENSG00000163644.10328.05030216.058100.602402.776902.00290HepG2CALR
PPM1KENSG00000163644.10623.83060356.033600.809007.350106.13680HepG2CIRBP
PPM1KENSG00000163644.10196.38700349.94670-0.833408.214907.18700HepG2CKAP4
PPM1KENSG00000163644.10140.25400212.04260-0.596302.302101.31350HepG2CSTF2
PPM1KENSG00000163644.10786.19800433.880000.857504.463303.68310HepG2DDX3X
PPM1KENSG00000163644.10110.56110276.53520-1.3226014.3826013.01050HepG2DNAJC2
PPM1KENSG00000163644.10473.97700358.300000.403502.008801.49410HepG2EIF2S1
PPM1KENSG00000163644.10631.33960396.661900.670405.763004.60750HepG2EIF4G2
PPM1KENSG00000163644.10269.40360393.33400-0.546002.912601.99530HepG2G3BP2
PPM1KENSG00000163644.10151.21560281.67620-0.897405.760204.87450HepG2HNRNPA1
PPM1KENSG00000163644.10178.93890313.31120-0.808104.959604.05140HepG2HNRNPC
PPM1KENSG00000163644.10346.84630227.288700.609703.295002.61410HepG2HNRNPLL
PPM1KENSG00000163644.10809.65720376.724801.1037013.9421012.55720HepG2IGF2BP2
PPM1KENSG00000163644.10192.76950317.92150-0.721806.096605.05100HepG2ILF2
PPM1KENSG00000163644.10209.98420319.96480-0.607604.648203.33370HepG2KIF1C
PPM1KENSG00000163644.10238.04380395.29730-0.731702.319401.56360HepG2LARP4
PPM1KENSG00000163644.10254.28220401.81490-0.660103.599102.88770HepG2MATR3
PPM1KENSG00000163644.10715.96150411.298500.799607.082906.09230HepG2NCBP2
PPM1KENSG00000163644.10136.91730308.07600-1.1700011.6819010.13590HepG2PARN
PPM1KENSG00000163644.1082.74830158.26840-0.935603.745502.31090HepG2PKM
PPM1KENSG00000163644.10131.69380277.60140-1.075809.387208.07280HepG2PPIL4
PPM1KENSG00000163644.10279.67650356.52130-0.350202.016801.47200HepG2PUS1
PPM1KENSG00000163644.10623.09190416.435600.581305.193004.37700HepG2QKI
PPM1KENSG00000163644.10622.19440377.929400.719103.913603.12230HepG2RBM25
PPM1KENSG00000163644.10333.79190427.90310-0.358302.092001.60780HepG2NELFE
PPM1KENSG00000163644.1076.20070186.20410-1.289006.582905.68010HepG2RPS19
PPM1KENSG00000163644.10137.59400293.70670-1.094007.390405.65390HepG2RPS5
PPM1KENSG00000163644.10193.24810277.17370-0.520303.060202.38890HepG2SAFB2
PPM1KENSG00000163644.10194.03490323.23290-0.736306.132905.23470HepG2SMN1
PPM1KENSG00000163644.10685.47330517.854900.404503.488102.94550HepG2SRFBP1
PPM1KENSG00000163644.10216.23070392.26910-0.859308.468807.45010HepG2SRSF5
PPM1KENSG00000163644.10285.55090446.11850-0.643706.133205.27430HepG2SUCLG1
PPM1KENSG00000163644.10555.12240375.537200.563703.966003.31350HepG2TAF15
PPM1KENSG00000163644.10510.82380345.101600.565704.493503.43620HepG2TIA1
PPM1KENSG00000163644.10191.74660302.43320-0.657404.312203.71630HepG2TIAL1
PPM1KENSG00000163644.10279.94070388.13840-0.471502.649601.79590HepG2TUFM
PPM1KENSG00000163644.10553.89800251.361001.139808.536107.43030HepG2U2AF1
PPM1KENSG00000163644.10112.34530198.46690-0.821003.700502.82410HepG2UCHL5
PPM1KENSG00000163644.10253.31460330.05020-0.381802.054101.43710HepG2UPF1
PPM1KENSG00000163644.10513.50570270.505200.924606.000604.15490HepG2XRCC5
PPM1KENSG00000163644.10202.53200330.70080-0.707403.469802.66340HepG2XRN2
PPM1KENSG00000163644.10294.18590191.450800.619702.648301.99000HepG2ZC3H8
PPM1KENSG00000163644.10222.03900362.99120-0.709106.589005.83980HepG2ZNF622
PPM1KENSG00000163644.10375.64140599.92070-0.675405.681503.92260K562ABCF1
PPM1KENSG00000163644.10514.04650731.42240-0.508805.312304.56700K562AGGF1
PPM1KENSG00000163644.10428.81060854.37700-0.9945011.4174010.34450K562AQR
PPM1KENSG00000163644.10321.91080533.25870-0.728206.147504.06860K562BCCIP
PPM1KENSG00000163644.10148.50530252.89010-0.768003.848402.56120K562CCAR1
PPM1KENSG00000163644.10671.80270874.09480-0.379803.114101.85090K562CCDC124
PPM1KENSG00000163644.10325.23720489.61200-0.590103.671101.96960K562CKAP4
PPM1KENSG00000163644.10406.36040738.07100-0.861005.280503.75390K562CNOT7
PPM1KENSG00000163644.10443.47390734.62980-0.728204.464003.03610K562CPEB4
PPM1KENSG00000163644.10176.12230286.15530-0.700202.619601.85580K562CPSF6
PPM1KENSG00000163644.10144.75570266.42940-0.880103.913001.66970K562DDX1
PPM1KENSG00000163644.10376.61250496.15590-0.397702.439901.46390K562DDX3X
PPM1KENSG00000163644.10374.91850759.88830-1.019207.894406.87020K562DDX47
PPM1KENSG00000163644.10165.95090283.08110-0.770504.743002.90560K562DHX30
PPM1KENSG00000163644.10302.96880495.40240-0.709403.783102.25410K562EEF2
PPM1KENSG00000163644.10346.69310478.72820-0.465502.363901.52200K562EFTUD2
PPM1KENSG00000163644.10257.11940485.25460-0.916301.953101.33040K562EIF2S2
PPM1KENSG00000163644.10139.08630257.24470-0.887203.642702.47140K562EIF3A
PPM1KENSG00000163644.10279.12840503.96680-0.852407.386306.09770K562EIF3G
PPM1KENSG00000163644.10369.29270518.37870-0.489202.070701.35720K562EIF4A3
PPM1KENSG00000163644.10670.37670997.54130-0.573407.575606.03510K562EIF4G2
PPM1KENSG00000163644.10262.14570431.23560-0.718105.410604.20040K562FIP1L1
PPM1KENSG00000163644.10182.27970291.10690-0.675402.598901.77090K562FMR1
PPM1KENSG00000163644.10315.16180479.94450-0.606803.492501.86620K562GEMIN5
PPM1KENSG00000163644.10213.97390437.70470-1.032509.935308.86080K562HNRNPC
PPM1KENSG00000163644.10435.06120686.80680-0.658703.221302.07180K562HNRNPL
PPM1KENSG00000163644.10239.02240354.69310-0.569402.871501.92090K562HNRNPM
PPM1KENSG00000163644.10368.34660584.67000-0.666605.456904.35610K562HSPD1
PPM1KENSG00000163644.10583.16530787.61000-0.433603.437702.06950K562IGF2BP3
PPM1KENSG00000163644.10592.10190773.16130-0.384902.652101.60550K562MAK16
PPM1KENSG00000163644.10172.62430266.69270-0.627502.204201.42230K562METAP2
PPM1KENSG00000163644.10245.52170471.40510-0.941107.802405.43870K562NONO
PPM1KENSG00000163644.10455.52950553.54810-0.281202.016101.36720K562NSUN2
PPM1KENSG00000163644.10454.26670709.06980-0.642403.695202.24660K562PABPC1
PPM1KENSG00000163644.10298.41550489.53150-0.714105.777204.51730K562PPIG
PPM1KENSG00000163644.10270.85980392.44220-0.534902.838201.91960K562PSIP1
PPM1KENSG00000163644.10912.471201134.23540-0.313902.201401.34320K562PUM2
PPM1KENSG00000163644.10157.09810269.71200-0.779803.476801.30980K562RBFOX2
PPM1KENSG00000163644.10526.99620758.48120-0.525304.497203.39610K562RBM22
PPM1KENSG00000163644.10436.21180660.20780-0.597905.433803.48510K562RBM25
PPM1KENSG00000163644.10257.84270358.02430-0.473602.493301.55630K562RCC2
PPM1KENSG00000163644.10555.43060798.13840-0.523004.247502.85970K562NELFE
PPM1KENSG00000163644.10444.82430706.85080-0.668204.582202.28670K562RECQL
PPM1KENSG00000163644.10363.17110496.28340-0.450503.185101.48420K562RPS10
PPM1KENSG00000163644.10268.98350474.61380-0.819205.161004.04310K562RPS19
PPM1KENSG00000163644.10312.02270476.41310-0.610602.777301.44850K562RRP9
PPM1KENSG00000163644.10522.04340723.69180-0.471204.234903.17190K562SF3B4
PPM1KENSG00000163644.10210.03360339.40040-0.692404.212702.87060K562SRFBP1
PPM1KENSG00000163644.10511.02100732.05650-0.518604.277002.92550K562SRSF5
PPM1KENSG00000163644.10289.75100451.20600-0.639003.082102.00950K562SUPV3L1
PPM1KENSG00000163644.10368.05290784.66360-1.0922012.5979010.89210K562TARDBP
PPM1KENSG00000163644.10278.71050411.20710-0.561103.085201.31180K562TFIP11
PPM1KENSG00000163644.10469.88090756.87580-0.687807.829606.34310K562TIA1
PPM1KENSG00000163644.10222.85310377.46720-0.760304.876803.60290K562TIAL1
PPM1KENSG00000163644.10430.89790696.65760-0.693107.812106.45260K562U2AF2
PPM1KENSG00000163644.10332.13010477.46690-0.523702.559301.58620K562UCHL5
PPM1KENSG00000163644.10308.60910587.54120-0.928908.589606.57690K562UTP3
PPM1KENSG00000163644.10640.86840962.47370-0.586706.162604.79220K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PPM1K is not available on ENCORE database.





2 RBPs can affect the splicing of PPM1K :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPPM1KENSG00000163644.10chr4-8919929589199794891982948919839589205557892058880.327000.000380.05948includedK562MATR3
A3SSPPM1KENSG00000163644.10chr4-8918615289186307891861528918628789189341891894860.310000.000020.00021longerK562AQR
A3SSPPM1KENSG00000163644.10chr4-8918372889183925891837288918387889186152891863070.419000.000060.00055longerK562AQR
A3SSPPM1KENSG00000163644.10chr4-8919829489198419891982948919839589199295891997940.472000.000080.00073longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PPM1K is not avaliable on ENCORE database.