POLR2B

General Information

Gene Name : POLR2B
Gene ID : ENSG00000047315.15
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: POLR2B)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	POLR2B	ENSG00000047315.15	90.75	76.67	83.71	ENCSR000AEF
HepG2	POLR2B	ENSG00000047315.15	60.84	77.96	69.40	ENCSR985KAT
K562	POLR2B	ENSG00000047315.15	97.95	93.87	95.91	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for POLR2B is not avaliable on ENCORE database.

Proteins bound to RNA

POLR2B RNA is bound by 26 proteins.

CanvasJS.com

eCLIP assay for POLR2B is not avaliable on ENCORE database.

26 proteins are bound to POLR2B RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr4	57861204	57861347	+	intron-Distal,intron-Proximal	4.71623	17.49466	K562	KHSRP
chr4	57883291	57883381	+	CDS	4.59327	16.02911	K562	LIN28B
chr4	57883324	57883408	+	CDS,intron-Proximal	3.05368	11.94287	K562	DDX24
chr4	57883435	57883469	+	intron-Proximal	4.94556	11.65116	K562	AQR
chr4	57883249	57883327	+	CDS	3.31671	10.35084	HepG2	BCLAF1
chr4	57883416	57883435	+	intron-Proximal	4.85334	10.08262	K562	AQR
chr4	57897184	57897301	+	3'-UTR	5.51668	9.76393	HepG2	SUB1
chr4	57860591	57860652	+	CDS	3.23935	9.04720	K562	ZNF622
chr4	57881671	57881713	+	CDS	4.07459	8.94445	HepG2	BCLAF1
chr4	57897202	57897262	+	3'-UTR	3.26251	8.86655	K562	KHSRP
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 80 entries

eCLIP assay for POLR2B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for POLR2B is not available on ENCORE database.
72 RBPs can affect the levels of POLR2B.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for POLR2B is not available on ENCORE database.

72 RBPs can affect the gene expression of POLR2B :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
POLR2B	ENSG00000047315.10	6047.97880	3037.58300	0.99340	57.45060	55.91650	HepG2	SRSF1
POLR2B	ENSG00000047315.10	1300.43210	2523.94300	-0.95670	25.89220	24.65330	HepG2	TIAL1
POLR2B	ENSG00000047315.10	1704.41120	2546.35270	-0.57920	15.03050	13.86620	HepG2	TRIM56
POLR2B	ENSG00000047315.10	8411.39460	4861.60530	0.79080	15.07960	13.85290	K562	PUS1
POLR2B	ENSG00000047315.10	7446.86460	5141.78120	0.53430	9.90460	8.58270	K562	SRSF1
POLR2B	ENSG00000047315.10	1606.91490	2316.62620	-0.52770	9.83000	8.48580	HepG2	PPIL4
POLR2B	ENSG00000047315.10	2332.39900	3167.47990	-0.44150	9.45000	8.22290	HepG2	HNRNPF
POLR2B	ENSG00000047315.10	2296.68800	3650.15660	-0.66840	8.96850	7.94500	K562	HNRNPC
POLR2B	ENSG00000047315.10	1762.20310	2307.66890	-0.38910	8.51450	7.44630	HepG2	DNAJC2
POLR2B	ENSG00000047315.10	5336.35590	7646.66000	-0.51900	8.79590	7.42930	K562	GRSF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 89 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for POLR2B is not available on ENCORE database.

4 RBPs can affect the splicing of POLR2B :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	POLR2B	ENSG00000047315.10	chr4	+	57874772	57874956			57872981	57873168	57876526	57876670	0.08700	0.00000	included	K562	AQR
SE	POLR2B	ENSG00000047315.10	chr4	+	57876209	57876366			57874818	57874956	57876526	57876670	-0.74200	0.00007	excluded	K562	AQR
SE	POLR2B	ENSG00000047315.10	chr4	+	57888317	57888412			57886992	57887161	57889495	57889746	-0.06000	0.00000	excluded	K562	AQR
SE	POLR2B	ENSG00000047315.10	chr4	+	57851425	57851623			57845061	57845170	57852519	57852592	0.07100	0.00002	included	K562	HNRNPC
A3SS	POLR2B	ENSG00000047315.10	chr4	+	57861370	57861575			57861416	57861575	57860812	57861032	0.05800	0.00000	longer	K562	AQR
A3SS	POLR2B	ENSG00000047315.10	chr4	+	57891511	57891703			57891542	57891703	57891031	57891165	0.08300	0.00000	longer	K562	AQR
MXE	POLR2B	ENSG00000047315.10	chr4	+	57889495	57889746	57889827	57889917	57887064	57887161	57890170	57890278	0.05800	0.00000	1included	K562	AQR
MXE	POLR2B	ENSG00000047315.10	chr4	+	57872942	57873168	57874818	57874956	57871765	57871885	57876526	57876670	-0.14600	0.00000	2included	K562	AQR
MXE	POLR2B	ENSG00000047315.10	chr4	+	57872981	57873168	57874818	57874956	57871765	57871885	57876526	57876670	-0.07400	0.00000	2included	K562	AQR
MXE	POLR2B	ENSG00000047315.10	chr4	+	57852519	57852592	57856913	57857064	57845108	57845170	57860569	57860682	-0.14300	0.00023	2included	HepG2	SF3A3

Showing 1 to 10 of 14 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

POLR2B

General Information

Functions

Localization

Domains (AlphaFold: POLR2B)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for POLR2B is not avaliable on ENCORE database.

26 proteins are bound to POLR2B RNA:

eCLIP assay for POLR2B is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for POLR2B is not available on ENCORE database.

72 RBPs can affect the gene expression of POLR2B :

The Knockdown/knockout RNA-Seq assay for POLR2B is not available on ENCORE database.

4 RBPs can affect the splicing of POLR2B :

The Knockdown/knockout RNA-Seq assay for POLR2B is not avaliable on ENCORE database.