MEAF6

General Information

Gene Name       : MEAF6
Gene ID             : ENSG00000163875.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MEAF6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MEAF6ENSG00000163875.1556.4649.1352.80ENCSR000AEF
HepG2MEAF6ENSG00000163875.1529.9452.2241.08ENCSR985KAT
K562MEAF6ENSG00000163875.1585.35101.6593.50ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MEAF6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MEAF6 RNA is bound by 19 proteins.  







eCLIP assay for MEAF6 is not avaliable on ENCORE database.





19 proteins are bound to MEAF6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr13795916137959249-3'-UTR,intron-Distal3.157164.91793HepG2FUBP3
chr13795912537959211-3'-UTR,intron-Distal6.5570928.09327K562TIA1
chr13795921137959223-3'-UTR,intron-Distal4.4652010.32245K562TIA1
chr13795910137959201-3'-UTR,intron-Distal3.7268912.09736K562IGF2BP1
chr13795917737959229-3'-UTR,intron-Distal3.116323.47089HepG2TIAL1
chr13795926237959331-3'-UTR,intron-Distal,intron-Proximal5.3394875.56685K562PUM2
chr13795936737959457-3'-UTR,CDS,intron-Distal,intron-Proximal4.080013.74246K562ZC3H11A
chr13795933137959439-3'-UTR,CDS,intron-Distal,intron-Proximal3.4167117.89722K562PUM2
chr13795916737959226-3'-UTR,intron-Distal3.314764.94579K562ZC3H11A
chr13795969537959767-3'-UTR,CDS,intron-Distal4.048885.47851K562SF3B4
chr13795935537959410-3'-UTR,CDS,intron-Distal,intron-Proximal3.454394.30970K562IGF2BP2
chr13798032837980374-5'-UTR,CDS,intron-Distal,intron-Proximal5.0321627.01324K562YBX3
chr13798025737980352-5'-UTR,CDS,intron-Distal,intron-Proximal3.889825.97131K562DDX3X
chr13797487737974925-CDS,intron-Distal,intron-Proximal3.660684.41267HepG2PPIG
chr13797902237979081-CDS,intron-Distal,intron-Proximal3.480893.68457K562LIN28B
chr13796738237967406-CDS,intron-Distal,intron-Proximal3.347654.63311K562AQR
chr13797505237975096-CDS,intron-Distal,intron-Proximal3.365344.89070K562UCHL5
chr13797487737974946-CDS,intron-Distal,intron-Proximal3.001674.05793K562AQR
chr13796735837967420-CDS,intron-Distal,intron-Proximal4.8342913.44390HepG2PRPF8
chr13797488037974924-CDS,intron-Distal3.184887.01182K562ZNF622
chr13798031337980328-CDS,intron-Distal,intron-Proximal4.4017420.87348K562YBX3
chr13798027037980313-CDS,intron-Distal,intron-Proximal3.180055.71779K562YBX3
chr13796754437967609-CDS,intron-Distal,intron-Proximal4.267183.79199HepG2PPIG
chr13797902237979045-CDS,intron-Distal,intron-Proximal3.631155.73766K562YBX3
chr13796177837961875-intron-Distal5.296308.71243HepG2QKI
chr13796177137961837-intron-Distal4.005237.46973K562KHSRP
chr13796238937962501-intron-Distal,intron-Proximal3.269846.60947K562KHSRP
chr13796182537961879-intron-Distal3.098604.46994K562QKI
chr13796255737962621-intron-Distal3.926323.50357HepG2QKI
chr13796736237967382-intron-Distal,intron-Proximal3.986075.26367K562AQR
chr13796388637963999-intron-Distal3.075113.02914K562KHDRBS1
chr13796223337962294-intron-Distal,intron-Proximal3.719947.82071K562KHSRP
chr13796729937967355-intron-Distal,intron-Proximal3.903714.93376K562PRPF8
chr13796170337961771-intron-Distal5.1737411.05731K562KHSRP
chr13796153537961586-intron-Distal,intron-Proximal4.604393.91589K562SF3B4
chr13796164037961690-intron-Distal3.448844.93120K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MEAF6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MEAF6 is not available on ENCORE database.

  • 75 RBPs can affect the levels of MEAF6.  








The Knockdown/knockout RNA-Seq assay for MEAF6 is not available on ENCORE database.





75 RBPs can affect the gene expression of MEAF6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MEAF6ENSG00000163875.111207.18860726.173300.7332016.0856014.87810HepG2ACO1
MEAF6ENSG00000163875.111946.74350958.129301.0227013.5409012.45610HepG2AKAP1
MEAF6ENSG00000163875.111355.20700907.081500.579105.075303.67790HepG2AKAP8
MEAF6ENSG00000163875.111228.22990729.586500.7513015.4921013.88430HepG2AKAP8L
MEAF6ENSG00000163875.111124.56010792.746500.504304.021103.08110HepG2ASCC1
MEAF6ENSG00000163875.111524.075201055.629100.529709.302608.16690HepG2AUH
MEAF6ENSG00000163875.111396.42490954.914500.548207.017705.86160HepG2CALR
MEAF6ENSG00000163875.11855.97190726.017200.237502.032401.44990HepG2CKAP4
MEAF6ENSG00000163875.11557.45220771.43280-0.468704.322103.05190HepG2YBX3
MEAF6ENSG00000163875.111281.61080962.682400.412705.352304.51090HepG2CELF1
MEAF6ENSG00000163875.11830.625301035.08450-0.317503.481502.66740HepG2DAZAP1
MEAF6ENSG00000163875.111317.97840917.761700.522004.290403.52600HepG2DDX3X
MEAF6ENSG00000163875.11453.03610757.56970-0.741806.428705.39350HepG2DNAJC21
MEAF6ENSG00000163875.111238.30520815.527200.602504.051803.22670HepG2EIF4B
MEAF6ENSG00000163875.111399.209601211.970600.207201.937701.41480HepG2ETF1
MEAF6ENSG00000163875.111176.71810709.602600.729604.607603.53500HepG2EWSR1
MEAF6ENSG00000163875.111682.901701076.072400.645105.831604.75520HepG2FIP1L1
MEAF6ENSG00000163875.111157.44690783.925400.562103.022802.32860HepG2G3BP1
MEAF6ENSG00000163875.111302.64670962.384400.436703.149002.47100HepG2GPKOW
MEAF6ENSG00000163875.11472.34660764.82610-0.695306.987906.03030HepG2HNRNPA1
MEAF6ENSG00000163875.11720.19300951.28940-0.401504.227303.11250HepG2HNRNPA2B1
MEAF6ENSG00000163875.11632.49380850.68880-0.427603.192802.45490HepG2HNRNPC
MEAF6ENSG00000163875.11922.804901146.20160-0.312803.205702.43770HepG2HNRNPF
MEAF6ENSG00000163875.11779.15200942.87200-0.275202.697102.03150HepG2HNRNPL
MEAF6ENSG00000163875.111336.06840918.416100.540703.840603.10910HepG2HNRNPLL
MEAF6ENSG00000163875.11418.93110845.06750-1.0124012.8070011.58070HepG2HNRNPU
MEAF6ENSG00000163875.11930.148001128.68430-0.279102.085801.45100HepG2IGF2BP1
MEAF6ENSG00000163875.111243.15680796.808700.641606.294605.31440HepG2IGF2BP2
MEAF6ENSG00000163875.11633.69280850.17120-0.424002.505901.90280HepG2MATR3
MEAF6ENSG00000163875.111064.88000870.860300.290102.020101.32360HepG2MSI2
MEAF6ENSG00000163875.111081.26560701.846500.623403.352602.36990HepG2PABPC1
MEAF6ENSG00000163875.11504.39180753.73940-0.579504.764803.82370HepG2PPIL4
MEAF6ENSG00000163875.11765.25120569.375700.426502.924002.09450HepG2PRPF8
MEAF6ENSG00000163875.111055.05300830.264000.345603.680703.06930HepG2PTBP1
MEAF6ENSG00000163875.111345.849701040.100100.371705.915805.11570HepG2PUM1
MEAF6ENSG00000163875.111385.298701039.333300.414404.609203.75400HepG2PUM2
MEAF6ENSG00000163875.111145.12150688.071400.734804.336403.46380HepG2RAVER1
MEAF6ENSG00000163875.111563.241801090.312800.519706.921605.64920HepG2RBM15
MEAF6ENSG00000163875.111693.516301012.990000.7413015.7591014.72850HepG2RBM22
MEAF6ENSG00000163875.111059.13020816.083000.376003.041002.33790HepG2RBM25
MEAF6ENSG00000163875.111131.79640924.007400.292502.667702.13410HepG2NELFE
MEAF6ENSG00000163875.11659.65480529.902400.315901.857401.34430HepG2RPS19
MEAF6ENSG00000163875.11940.47920714.556000.396203.060701.92900HepG2RPS5
MEAF6ENSG00000163875.11796.02190563.244700.498903.461502.59600HepG2RRP9
MEAF6ENSG00000163875.11457.50730752.59280-0.718108.506007.46750HepG2SAFB2
MEAF6ENSG00000163875.11510.92610726.20120-0.507303.031501.66460HepG2SART3
MEAF6ENSG00000163875.11716.35830531.776900.429802.909201.94440HepG2SERBP1
MEAF6ENSG00000163875.111743.36490899.678800.9543010.302508.93580HepG2SF3A3
MEAF6ENSG00000163875.11751.94330939.48790-0.321303.309202.55270HepG2SLBP
MEAF6ENSG00000163875.111379.560601144.147000.269803.025302.50870HepG2SRFBP1
MEAF6ENSG00000163875.111195.80930902.263500.406305.158804.56440HepG2SRSF1
MEAF6ENSG00000163875.111506.31930978.085400.622905.096603.70070HepG2SRSF3
MEAF6ENSG00000163875.111273.90950967.412100.397005.302604.47700HepG2SRSF5
MEAF6ENSG00000163875.11914.04630734.036900.316303.108902.53060HepG2SRSF9
MEAF6ENSG00000163875.111244.69250734.610500.760607.906306.85770HepG2SUPV3L1
MEAF6ENSG00000163875.11558.45570821.28660-0.556404.876204.25090HepG2TIAL1
MEAF6ENSG00000163875.11660.40390828.47190-0.327102.472301.93240HepG2TRIM56
MEAF6ENSG00000163875.111447.02050920.485900.652507.174006.17000HepG2U2AF1
MEAF6ENSG00000163875.111320.709101013.225700.382302.381901.60920HepG2UBE2L3
MEAF6ENSG00000163875.111225.93510770.321800.6702012.8417011.69280HepG2UTP3
MEAF6ENSG00000163875.11505.71940723.14220-0.515903.071302.30830HepG2XRN2
MEAF6ENSG00000163875.111326.93630736.504000.8492022.9828021.38480HepG2ZC3H8
MEAF6ENSG00000163875.111652.05650877.513900.9127027.6912026.41920HepG2ZNF622
MEAF6ENSG00000163875.112536.538802227.023300.187601.979201.48370K562AGGF1
MEAF6ENSG00000163875.112868.005402317.296100.307502.679202.03640K562AKAP8L
MEAF6ENSG00000163875.112102.854402566.75420-0.287602.447701.88940K562AQR
MEAF6ENSG00000163875.112882.160402431.358800.245302.612901.72700K562ATP5C1
MEAF6ENSG00000163875.113121.573202493.718200.323904.526603.36800K562DKC1
MEAF6ENSG00000163875.11633.40690945.62240-0.578105.630503.70630K562DNAJC21
MEAF6ENSG00000163875.112622.112802104.003200.317502.771901.92280K562FIP1L1
MEAF6ENSG00000163875.111450.477201809.34990-0.318902.672401.89050K562GPKOW
MEAF6ENSG00000163875.11775.229001400.15610-0.852909.203508.16530K562HNRNPC
MEAF6ENSG00000163875.112370.727301730.652900.453903.861102.74930K562HNRNPM
MEAF6ENSG00000163875.111168.502001834.43990-0.6507012.5839010.71680K562HNRNPU
MEAF6ENSG00000163875.113917.824702852.469200.457705.309104.22460K562HSPD1
MEAF6ENSG00000163875.113350.629802459.309500.446105.154003.95790K562KIF1C
MEAF6ENSG00000163875.113462.425702755.036800.329603.178102.19160K562MBNL1
MEAF6ENSG00000163875.112651.048301931.074300.457103.168102.21270K562NAA15
MEAF6ENSG00000163875.114265.614002298.283600.8921017.7808016.44150K562PUS1
MEAF6ENSG00000163875.113206.368002239.197100.517909.700508.61630K562RBM15
MEAF6ENSG00000163875.111249.194901513.22430-0.276602.489401.67900K562SF3B4
MEAF6ENSG00000163875.111944.979401455.377200.418305.175904.04540K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MEAF6 is not available on ENCORE database.





12 RBPs can affect the splicing of MEAF6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMEAF6ENSG00000163875.11chr1-3796214737962205379614743796151937967404379675970.246000.000000.00003includedK562SRSF1
SEMEAF6ENSG00000163875.11chr1-3795952537959708379593623795941537967404379675970.366000.000480.01143includedK562SF3B4
SEMEAF6ENSG00000163875.11chr1-379621473796220537961474379615193796740437967597-0.147000.002230.06730excludedK562PRPF8
SEMEAF6ENSG00000163875.11chr1-3796214737962205379614743796151937967404379675970.084000.003650.05901includedHepG2U2AF1
SEMEAF6ENSG00000163875.11chr1-3795952537959764379593623795941537967404379675970.136000.008630.07224includedK562AQR
SEMEAF6ENSG00000163875.11chr1-3795952537959708379593623795941537967404379675970.286000.001180.01955includedK562PUS1
SEMEAF6ENSG00000163875.11chr1-379621473796220537961474379615193796740437967588-0.112000.000000.00001excludedK562HNRNPL
SEMEAF6ENSG00000163875.11chr1-379614853796151937959362379594153796740437967597-0.121000.000220.02718excludedHepG2SUPV3L1
SEMEAF6ENSG00000163875.11chr1-3795952537959708379593623795941537967404379675970.320000.000880.02482includedK562RBM15
SEMEAF6ENSG00000163875.11chr1-3796214737962205379614743796151937967404379675970.151000.001250.04756includedK562PTBP1
SEMEAF6ENSG00000163875.11chr1-379614853796151937959362379594153796740437967597-0.131000.000050.00153excludedK562HNRNPC
A3SSMEAF6ENSG00000163875.11chr1-3795952537959764379595253795970837961485379616130.065000.000000.00000longerK562AQR
MXEMEAF6ENSG00000163875.11chr1-3796214737962205379674043796759737961485379615193797487837974924-0.053000.002640.068952includedK562PTBP1
MXEMEAF6ENSG00000163875.11chr1-3796214737962205379674043796759737961485379615193797487837974924-0.052000.002480.038662includedK562SRSF1
MXEMEAF6ENSG00000163875.11chr1-3796740437967597379748783797492437962147379622053797505537975143-0.088000.000070.002262includedK562SRSF1
MXEMEAF6ENSG00000163875.11chr1-37961485379615193796740437967597379589983795970837974878379749240.086000.008280.054341includedK562AQR
MXEMEAF6ENSG00000163875.11chr1-3796740437967597379748783797492437961485379615193797505537975143-0.147000.002270.030592includedK562U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MEAF6 is not avaliable on ENCORE database.