MAVS

General Information

Gene Name       : MAVS
Gene ID             : ENSG00000088888.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MAVS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MAVSENSG00000088888.179.1510.659.90ENCSR000AEF
HepG2MAVSENSG00000088888.1723.9321.5922.76ENCSR985KAT
K562MAVSENSG00000088888.1710.519.6010.05ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MAVS is not avaliable on ENCORE database.



Proteins bound to RNA
  • MAVS RNA is bound by 21 proteins.  







eCLIP assay for MAVS is not avaliable on ENCORE database.





21 proteins are bound to MAVS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2038469193846949+3'-UTR4.532969.30447HepG2UPF1
chr2038420143842100+3'-UTR,CDS,intron-Distal3.280963.24162HepG2G3BP1
chr2038473333847445+3'-UTR5.7430229.01090HepG2AKAP1
chr2038469703847062+3'-UTR4.4982222.74836HepG2AKAP1
chr2038471653847267+3'-UTR5.6666840.78951HepG2UPF1
chr2038477383847758+3'-UTR5.167769.25213HepG2UPF1
chr2038471573847266+3'-UTR4.0917815.58180HepG2AKAP1
chr2038487483848922+3'-UTR3.313669.15555HepG2PCBP2
chr2038451743845269+3'-UTR,CDS3.404004.30677K562YBX3
chr2038479483848016+3'-UTR5.0496513.75064K562UPF1
chr2038469123846967+3'-UTR4.264338.75386HepG2AKAP1
chr2038472673847333+3'-UTR4.477439.26660HepG2AKAP1
chr2038480963848156+3'-UTR3.0566210.20264HepG2UPF1
chr2038451183845171+3'-UTR,CDS3.849043.01531K562YBX3
chr2038471843847239+3'-UTR3.487716.80152HepG2NKRF
chr2038473563847389+3'-UTR5.510189.83131K562UPF1
chr2038473323847384+3'-UTR3.102763.37567HepG2HNRNPK
chr2038475643847603+3'-UTR3.799096.55257K562UPF1
chr2038464013846446+3'-UTR,CDS3.191186.28230HepG2PPIG
chr2038480953848146+3'-UTR4.9104111.62373K562UPF1
chr2038488633848899+3'-UTR3.133653.32115K562AKAP1
chr2038476813847770+3'-UTR3.456006.23201HepG2AKAP1
chr2038488303848924+3'-UTR3.119635.03045K562ILF3
chr2038474853847539+3'-UTR4.215199.71169K562UPF1
chr2038489153848971+3'-UTR4.1577911.60337K562UPF1
chr2038484243848469+3'-UTR4.0471612.91816K562UPF1
chr2038474453847529+3'-UTR4.9040815.05372HepG2AKAP1
chr2038470653847165+3'-UTR6.0417755.94715HepG2UPF1
chr2038470173847058+3'-UTR3.109837.47822K562UPF1
chr2038483293848402+3'-UTR4.4716620.29077K562UPF1
chr2038470623847157+3'-UTR4.9356430.99772HepG2AKAP1
chr2038448723844932+3'-UTR,CDS,intron-Proximal3.453517.54792HepG2PRPF8
chr2038453333845369+3'-UTR,CDS4.007033.73296HepG2IGF2BP1
chr2038429613843045+3'-UTR,CDS3.082727.10982HepG2GRWD1
chr2038470583847209+3'-UTR3.6345623.02085K562UPF1
chr2038478683847906+3'-UTR3.900768.71030K562UPF1
chr2038488103848915+3'-UTR3.212316.94500HepG2HNRNPK
chr2038469583847065+3'-UTR5.1606147.65807HepG2UPF1
chr2038476943847715+3'-UTR4.204767.35773HepG2UPF1
chr2038448563844918+3'-UTR,CDS,intron-Proximal4.548755.25202HepG2AQR
chr2038480213848082+3'-UTR6.1407514.85952K562UPF1
chr2038473223847448+3'-UTR4.5615132.44501HepG2UPF1
chr2038488563848915+3'-UTR4.5830216.98297K562UPF1
chr2038472673847322+3'-UTR5.2865319.90509HepG2UPF1
chr2038470603847163+3'-UTR4.651158.40136K562AKAP1
chr2038468783846950+3'-UTR3.485938.80318HepG2NKRF
chr2038275263827597+5'-UTR,intron-Proximal3.630256.74268HepG2PRPF8
chr2038275023827556+5'-UTR,intron-Proximal3.5567913.52596HepG2DDX3X
chr2038352033835288+5'-UTR,CDS,intron-Proximal3.912328.75653HepG2DDX3X
chr2038352423835266+5'-UTR3.575514.22917HepG2PPIG
chr2038277953827868+intron-Distal4.003376.49249HepG2EFTUD2
chr2038277663827876+intron-Distal3.002475.88353HepG2CSTF2T
chr2038277983827869+intron-Distal4.752678.64430HepG2RBM22
chr2038278213827865+intron-Distal3.230543.12255HepG2XPO5
chr2038397643839851+intron-Distal4.176806.90077HepG2PTBP1
chr2038459823846024+intron-Distal3.704313.60408HepG2XPO5
chr2038297303829829+intron-Distal3.904803.41442HepG2HNRNPK
chr2038277663827851+intron-Distal4.142873.29554HepG2GTF2F1
chr2038377943837878+intron-Distal3.625824.48652HepG2PTBP1
chr2038402313840279+intron-Distal3.960633.48745HepG2ILF3
chr2038388423838935+intron-Distal6.4613140.09856HepG2PCBP2
chr2038402793840355+intron-Distal3.209523.09748HepG2ILF3
chr2038397583839872+intron-Distal5.752929.83211HepG2PCBP2
chr2038277673827873+intron-Distal5.099648.80329HepG2PRPF4
chr2038403813840439+intron-Distal4.932157.34252HepG2PCBP2
chr2038388543838998+intron-Distal3.102763.37567HepG2HNRNPK
chr2038454353845528+intron-Proximal5.814049.23760K562AQR
chr2038275823827648+intron-Proximal5.641798.08771HepG2EFTUD2
chr2038430603843130+intron-Proximal4.124753.59236HepG2AQR
chr2038454353845497+intron-Proximal4.094056.58230HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MAVS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MAVS is not available on ENCORE database.

  • 86 RBPs can affect the levels of MAVS.  








The Knockdown/knockout RNA-Seq assay for MAVS is not available on ENCORE database.





86 RBPs can affect the gene expression of MAVS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MAVSENSG00000088888.132537.013703042.20680-0.262003.472002.71860HepG2AUH
MAVSENSG00000088888.131007.015001357.02480-0.430402.760001.82480HepG2BCCIP
MAVSENSG00000088888.131417.989602006.73940-0.501005.658404.83940HepG2BOP1
MAVSENSG00000088888.131112.600701519.94230-0.450105.055404.05110HepG2CALR
MAVSENSG00000088888.131295.679801842.28780-0.507805.334104.40900HepG2CPSF6
MAVSENSG00000088888.131775.681801334.336800.412202.139001.45110HepG2DDX55
MAVSENSG00000088888.131814.513201468.290000.305303.571302.84810HepG2DNAJC2
MAVSENSG00000088888.131904.956902313.76970-0.280502.511301.40090HepG2EIF2S2
MAVSENSG00000088888.133106.563001899.871300.709305.631604.71930HepG2EIF4A3
MAVSENSG00000088888.131234.192101469.44120-0.251702.449901.65440HepG2EIF4G1
MAVSENSG00000088888.131994.213903492.94480-0.8086028.5279026.93820HepG2ETF1
MAVSENSG00000088888.131931.852301495.503000.369303.616402.89120HepG2HNRNPA1
MAVSENSG00000088888.133144.824302213.532300.5065012.2241010.86390HepG2HNRNPF
MAVSENSG00000088888.131263.261501800.74720-0.511405.314404.37010HepG2HNRNPK
MAVSENSG00000088888.131393.542801652.49090-0.245902.758302.15170HepG2HNRNPU
MAVSENSG00000088888.132237.511802906.60870-0.377402.571501.39110HepG2HSPD1
MAVSENSG00000088888.132750.851902179.707900.335603.944903.09340HepG2IGF2BP1
MAVSENSG00000088888.132225.223901807.520300.299802.053401.46280HepG2IGF2BP2
MAVSENSG00000088888.132100.572002492.63330-0.246902.052101.35000HepG2MSI2
MAVSENSG00000088888.131962.207601476.981600.409705.287004.23900HepG2NOL12
MAVSENSG00000088888.131241.338401635.65830-0.398005.884404.71890HepG2PARN
MAVSENSG00000088888.131631.877702243.69720-0.459308.500707.24790HepG2PRPF4
MAVSENSG00000088888.132331.794401496.650200.6396021.0690019.74090HepG2PUM1
MAVSENSG00000088888.132034.256801495.566600.443705.800504.84210HepG2PUM2
MAVSENSG00000088888.131350.439302064.57160-0.6124011.3110010.17430HepG2QKI
MAVSENSG00000088888.133489.478902956.855100.238802.372201.57210HepG2RBM15
MAVSENSG00000088888.132538.822502919.43790-0.201501.914101.46200HepG2RBM22
MAVSENSG00000088888.132251.180201975.772100.188201.856701.33700HepG2RECQL
MAVSENSG00000088888.132981.653302384.359400.322403.069302.35570HepG2RPLP0
MAVSENSG00000088888.13793.038901017.64230-0.359802.477501.73010HepG2RRP9
MAVSENSG00000088888.131921.40770933.488301.041403.428601.87960HepG2SF1
MAVSENSG00000088888.131751.162603013.89260-0.783302.896502.20630HepG2SF3A3
MAVSENSG00000088888.132084.505901351.837500.6247017.8794016.38680HepG2SLBP
MAVSENSG00000088888.131539.11750834.570000.882902.813301.49200HepG2SNRNP200
MAVSENSG00000088888.132472.076103297.36660-0.415609.954209.16360HepG2SRFBP1
MAVSENSG00000088888.131268.767902122.58360-0.742407.404305.70210HepG2SRSF3
MAVSENSG00000088888.131951.825801392.047200.487509.269708.21400HepG2SRSF5
MAVSENSG00000088888.132745.150402174.686000.336005.714904.77200HepG2SRSF7
MAVSENSG00000088888.132217.062502862.84060-0.368807.103506.35480HepG2SSB
MAVSENSG00000088888.13729.480401066.51440-0.548003.676302.39040HepG2STIP1
MAVSENSG00000088888.132527.864601583.157200.6750021.5340020.06230HepG2SUCLG1
MAVSENSG00000088888.132149.734602932.08570-0.447803.165101.74060HepG2SUGP2
MAVSENSG00000088888.131342.756401861.88430-0.471607.303206.46740HepG2TAF15
MAVSENSG00000088888.132270.554801377.382200.7210012.9555010.87960HepG2TUFM
MAVSENSG00000088888.132132.200302634.64380-0.305302.295801.71870HepG2U2AF1
MAVSENSG00000088888.132508.146401457.920700.782603.810302.82220HepG2UBE2L3
MAVSENSG00000088888.13563.63480784.47720-0.477003.072002.27350HepG2UCHL5
MAVSENSG00000088888.132069.123202672.86060-0.369407.143506.10840HepG2UPF1
MAVSENSG00000088888.13677.469701215.77650-0.843607.083305.43320HepG2UPF2
MAVSENSG00000088888.132179.980302747.33690-0.333705.114303.73200HepG2UTP18
MAVSENSG00000088888.13695.588101097.95100-0.658503.764202.48010HepG2XPO5
MAVSENSG00000088888.13870.298001307.42940-0.587204.338103.43540HepG2XRN2
MAVSENSG00000088888.131450.247802214.23380-0.6105017.5154016.07960HepG2ZC3H8
MAVSENSG00000088888.13548.749001286.98770-1.2298013.5937012.43760K562AGGF1
MAVSENSG00000088888.13744.363501414.02750-0.925707.360505.55560K562AKAP8
MAVSENSG00000088888.13511.696701339.12540-1.3879017.4765015.56690K562AKAP8L
MAVSENSG00000088888.13648.248001072.38310-0.726208.090307.17460K562AQR
MAVSENSG00000088888.13818.067901404.98240-0.780308.429806.70460K562ATP5C1
MAVSENSG00000088888.131035.850901538.16280-0.570404.485702.94650K562CCDC124
MAVSENSG00000088888.131665.358902114.05740-0.344203.688002.55680K562CELF1
MAVSENSG00000088888.13659.248701441.26860-1.1284012.6653010.48520K562DKC1
MAVSENSG00000088888.131135.75350784.389600.533902.660201.67860K562EIF3A
MAVSENSG00000088888.13547.80200419.841900.383702.790201.99080K562EIF3G
MAVSENSG00000088888.13742.72340554.333900.422002.586801.79330K562EIF4A3
MAVSENSG00000088888.13496.85820699.83890-0.494203.324102.06840K562FKBP4
MAVSENSG00000088888.13821.19260576.475200.510403.966903.26170K562FXR1
MAVSENSG00000088888.13140.49780296.32340-1.076606.849505.62560K562G3BP2
MAVSENSG00000088888.131015.966801468.01080-0.531005.897604.78990K562GRSF1
MAVSENSG00000088888.131398.079901113.293500.328502.448601.60770K562HNRNPU
MAVSENSG00000088888.131124.113401472.39290-0.389403.273502.41010K562HSPD1
MAVSENSG00000088888.13542.445401421.29980-1.3897016.7944014.08520K562KIF1C
MAVSENSG00000088888.13595.877201360.40950-1.1910010.748908.17810K562MAK16
MAVSENSG00000088888.13715.04200496.698800.525604.900603.63480K562MATR3
MAVSENSG00000088888.13750.946301592.19340-1.084205.963804.53240K562MBNL1
MAVSENSG00000088888.13385.072301115.99880-1.5351010.986008.78030K562NAA15
MAVSENSG00000088888.13332.54920603.14700-0.858904.102602.83690K562PABPN1
MAVSENSG00000088888.13944.079901232.76690-0.384903.005302.14630K562PPIG
MAVSENSG00000088888.13395.73620698.21850-0.819108.113806.82570K562PRPF8
MAVSENSG00000088888.13651.04410483.617900.428803.406402.67860K562PTBP1
MAVSENSG00000088888.131503.771901876.05640-0.319102.315701.56920K562PUF60
MAVSENSG00000088888.13317.775201328.35730-2.0636025.3333023.69860K562PUS1
MAVSENSG00000088888.13139.43590282.75690-1.020004.654402.74690K562RAVER1
MAVSENSG00000088888.13490.713801294.02520-1.3989017.0902015.59770K562RBM15
MAVSENSG00000088888.13683.38400463.577600.559803.085602.19410K562RBM22
MAVSENSG00000088888.13195.42850281.20130-0.525002.613301.32970K562RBM25
MAVSENSG00000088888.13716.03300452.017800.663505.852203.63130K562RBM34
MAVSENSG00000088888.13880.91560545.671600.690903.429702.30440K562RPS3
MAVSENSG00000088888.131320.911401059.271700.318402.514801.48340K562SAFB
MAVSENSG00000088888.131071.95250672.246200.673102.610501.36070K562SFPQ
MAVSENSG00000088888.13333.38860633.50270-0.926103.974402.40690K562SNRNP200
MAVSENSG00000088888.13773.04250526.665600.553604.820403.36900K562SRSF4
MAVSENSG00000088888.13187.17720296.75290-0.664904.238703.24830K562U2AF2
MAVSENSG00000088888.13630.039701346.49990-1.095708.201305.68920K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MAVS is not available on ENCORE database.





16 RBPs can affect the splicing of MAVS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMAVSENSG00000088888.13chr20+3841978384215138382813838456384290038430600.109000.001180.03085includedHepG2HNRNPK
SEMAVSENSG00000088888.13chr20+3841978384215138352043835388384290038430600.052000.002400.02930includedHepG2U2AF2
SEMAVSENSG00000088888.13chr20+384197838421513838281383845638429003843060-0.129000.003360.06526excludedHepG2SRSF1
SEMAVSENSG00000088888.13chr20+383828138384563835204383538838419783842151-0.177000.000290.00664excludedK562HNRNPC
A3SSMAVSENSG00000088888.13chr20+3838258383845638382813838456383520438353880.063000.005780.03285longerK562AQR
MXEMAVSENSG00000088888.13chr20+383520438353883841978384215138274863827550384290038430600.166000.000640.062361includedHepG2FUBP3
MXEMAVSENSG00000088888.13chr20+383520438353883838281383845638274893827550384197838421510.154000.001390.022771includedK562DROSHA
MXEMAVSENSG00000088888.13chr20+383520438353883838281383845638274893827550384197838421510.187000.000010.000881includedHepG2TAF15
MXEMAVSENSG00000088888.13chr20+383825838384563841978384215138352043835388384290038430600.151000.003380.025861includedK562AQR
MXEMAVSENSG00000088888.13chr20+38352043835388383828138384563827489382755038419783842151-0.238000.000000.000002includedHepG2NOLC1
MXEMAVSENSG00000088888.13chr20+38382813838456384197838421513835204383538838429003843060-0.350000.000000.000002includedHepG2SFPQ
MXEMAVSENSG00000088888.13chr20+38352043835388383828138384563827489382755038419783842151-0.166000.000380.072412includedHepG2LARP7
MXEMAVSENSG00000088888.13chr20+38352043835388383828138384563827489382755038419783842151-0.162000.000550.041662includedHepG2NOL12
MXEMAVSENSG00000088888.13chr20+38382813838456384197838421513835204383538838429003843060-0.344000.000000.000002includedHepG2U2AF2
MXEMAVSENSG00000088888.13chr20+38382813838456384197838421513835204383538838429003843060-0.242000.000020.001732includedHepG2RBFOX2
MXEMAVSENSG00000088888.13chr20+38352043835388383828138384563827489382755038419783842151-0.152000.001670.050672includedHepG2HNRNPC
MXEMAVSENSG00000088888.13chr20+383828138384563841978384215138352043835388384290038430600.146000.001620.041521includedK562PPIL4
MXEMAVSENSG00000088888.13chr20+38352043835388383828138384563827489382755038419783842151-0.197000.000130.020292includedHepG2ILF3
MXEMAVSENSG00000088888.13chr20+38352043835388383828138384563827489382755038419783842151-0.190000.000000.003322includedHepG2SND1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MAVS is not avaliable on ENCORE database.