LRCH3

General Information

Gene Name       : LRCH3
Gene ID             : ENSG00000186001.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LRCH3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LRCH3ENSG00000186001.1331.2430.5730.91ENCSR000AEF
HepG2LRCH3ENSG00000186001.1329.9942.6436.31ENCSR985KAT
K562LRCH3ENSG00000186001.1339.8138.2139.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LRCH3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LRCH3 RNA is bound by 30 proteins.  







eCLIP assay for LRCH3 is not avaliable on ENCORE database.





30 proteins are bound to LRCH3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3197598269197598345+3'-UTR,CDS,intron-Proximal4.987618.81987K562TIA1
chr3197611288197611415+3'-UTR,intron-Distal3.002135.24406K562AKAP1
chr3197598195197598362+3'-UTR,CDS,intron-Proximal3.935369.73062HepG2GRWD1
chr3197615145197615267+3'-UTR3.362203.29213HepG2KHSRP
chr3197598325197598397+3'-UTR,CDS,intron-Proximal4.167365.26367K562AQR
chr3197553735197553791+3'-UTR,CDS,intron-Proximal3.650454.35112K562U2AF1
chr3197547222197547306+3'-UTR,CDS,intron-Distal,intron-Proximal3.6720513.26331HepG2BCLAF1
chr3197611268197611433+3'-UTR,intron-Distal4.525275.78279HepG2ILF3
chr3197553729197553785+3'-UTR,CDS,intron-Proximal3.255867.34034HepG2U2AF2
chr3197612395197612471+3'-UTR,intron-Proximal3.397678.05410K562AKAP1
chr3197610521197610599+3'-UTR,CDS3.737163.24881HepG2SRSF1
chr3197611244197611448+3'-UTR,intron-Distal3.219826.38902HepG2UPF1
chr3197610532197610621+3'-UTR,CDS4.032893.81597K562RBM15
chr3197610075197610174+3'-UTR,intron-Distal3.067873.73266K562KHSRP
chr3197610174197610243+3'-UTR,intron-Distal3.805263.66668K562KHSRP
chr3197610442197610515+3'-UTR,CDS4.494914.82934K562RBM15
chr3197612392197612477+3'-UTR,intron-Proximal3.302723.27901HepG2UPF1
chr3197598278197598374+3'-UTR,CDS,intron-Proximal4.330105.34978HepG2PRPF8
chr3197611329197611385+3'-UTR,intron-Distal4.348885.48888K562XRCC6
chr3197553733197553788+3'-UTR,CDS,intron-Proximal4.996109.89122K562U2AF2
chr3197556493197556545+5'-UTR,CDS,intron-Proximal3.236684.24993HepG2PPIG
chr3197557639197557693+5'-UTR,CDS,intron-Proximal3.484066.20926HepG2PPIG
chr3197557606197557672+5'-UTR,CDS,intron-Proximal3.715597.62845K562SF3B4
chr3197562651197562696+5'-UTR,CDS,intron-Proximal3.805354.17155HepG2BCLAF1
chr3197562507197562598+5'-UTR,CDS,intron-Proximal3.758094.65797K562TARDBP
chr3197518125197518271+5'-UTR,CDS3.121108.40269HepG2NCBP2
chr3197559139197559191+5'-UTR,CDS,intron-Proximal3.729543.69481K562UCHL5
chr3197562520197562647+5'-UTR,CDS,intron-Proximal3.106887.10910K562UCHL5
chr3197566237197566272+CDS,intron-Proximal3.375534.14618K562ZNF622
chr3197574742197574779+CDS,intron-Proximal3.164314.76953K562DDX24
chr3197574278197574330+CDS,intron-Proximal4.211689.53524K562DDX24
chr3197597091197597148+CDS3.272646.02862HepG2GRWD1
chr3197579488197579534+CDS,intron-Proximal3.199635.11990K562AQR
chr3197574883197574990+CDS,intron-Proximal4.385417.53589K562AQR
chr3197581245197581308+CDS,intron-Proximal3.277333.73965HepG2U2AF1
chr3197574784197574907+CDS,intron-Proximal3.569969.83905HepG2BCLAF1
chr3197597032197597150+CDS,intron-Proximal3.832327.01786K562GRWD1
chr3197574882197574936+CDS,intron-Proximal3.496917.76128K562PRPF8
chr3197574742197574846+CDS,intron-Proximal3.386337.16988HepG2PPIG
chr3197602514197602574+CDS,intron-Proximal4.845473.42835K562SF3B4
chr3197562671197562694+CDS,intron-Proximal3.255563.31745K562ZNF622
chr3197574264197574319+CDS,intron-Proximal3.227433.75792K562U2AF2
chr3197574751197574905+CDS,intron-Proximal4.081129.95292HepG2GRWD1
chr3197581245197581305+CDS,intron-Proximal4.067154.08501K562U2AF2
chr3197579368197579466+CDS,intron-Proximal5.4728713.53654K562SF3B4
chr3197597032197597091+CDS3.606327.52317HepG2GRWD1
chr3197574867197574883+CDS4.168289.68077HepG2PRPF8
chr3197579488197579605+CDS,intron-Distal,intron-Proximal3.8812110.93931K562KHSRP
chr3197598195197598276+CDS,intron-Proximal4.755786.15968K562UCHL5
chr3197597035197597148+CDS3.622978.91541K562UCHL5
chr3197574266197574323+CDS,intron-Proximal4.226453.60286K562U2AF1
chr3197574779197574878+CDS3.073828.13987K562DDX24
chr3197574883197574933+CDS,intron-Proximal4.9197113.80141HepG2PRPF8
chr3197597028197597144+CDS,intron-Proximal3.1149110.41902K562ZNF622
chr3197574750197574892+CDS3.4354211.13035K562UCHL5
chr3197566207197566270+CDS,intron-Proximal3.841328.55049K562DDX24
chr3197593055197593096+CDS,intron-Distal,intron-Proximal4.144083.81597K562RBM15
chr3197574279197574287+CDS,intron-Proximal3.320097.21479K562UCHL5
chr3197574846197574892+CDS3.224206.27819HepG2PPIG
chr3197580986197581059+intron-Distal3.277333.73965HepG2U2AF1
chr3197565664197565775+intron-Distal3.028513.76473K562KHSRP
chr3197566311197566387+intron-Distal,intron-Proximal4.151064.79477K562KHSRP
chr3197606023197606127+intron-Distal4.620036.43804HepG2CSTF2
chr3197591763197591871+intron-Distal3.668153.00349HepG2ILF3
chr3197575545197575589+intron-Distal3.941353.35109HepG2TIAL1
chr3197593289197593392+intron-Distal3.122906.62024K562KHSRP
chr3197575407197575430+intron-Distal4.3057411.86374K562KHSRP
chr3197584011197584051+intron-Distal4.340704.68586HepG2HNRNPL
chr3197582999197583085+intron-Distal4.138303.14375HepG2RBFOX2
chr3197548034197548097+intron-Distal3.979433.06853K562LIN28B
chr3197605437197605508+intron-Distal3.787573.14359HepG2HNRNPK
chr3197556312197556407+intron-Distal,intron-Proximal4.048767.84449K562KHSRP
chr3197558187197558248+intron-Distal3.959323.45805K562KHSRP
chr3197605922197606044+intron-Distal4.242494.54401K562KHSRP
chr3197580889197580974+intron-Distal3.494428.05068K562KHSRP
chr3197575681197575716+intron-Distal3.365203.48890K562KHSRP
chr3197558275197558369+intron-Distal4.088783.66668K562KHSRP
chr3197575311197575406+intron-Distal3.580247.53262HepG2QKI
chr3197575355197575407+intron-Distal4.0323910.16833K562KHSRP
chr3197589954197590066+intron-Distal3.059576.39602K562KHSRP
chr3197575430197575474+intron-Distal3.603448.24998K562KHSRP
chr3197574992197575066+intron-Distal5.057868.72817K562KHSRP
chr3197576289197576401+intron-Distal3.213968.44889K562KHSRP
chr3197518883197519065+intron-Distal5.4347511.58578K562TARDBP
chr3197591746197591844+intron-Distal4.315793.31709K562ILF3
chr3197559254197559305+intron-Distal,intron-Proximal4.127143.02181K562PRPF8
chr3197575488197575542+intron-Distal3.870888.44734K562KHSRP
chr3197575283197575422+intron-Distal4.405886.30952K562QKI
chr3197576301197576400+intron-Distal5.4424210.09004HepG2QKI
chr3197575537197575592+intron-Distal3.461865.64899HepG2KHSRP
chr3197583957197584011+intron-Distal3.626994.23017HepG2HNRNPL
chr3197529669197529780+intron-Distal4.231863.88340K562TARDBP
chr3197580978197581064+intron-Distal4.2888720.59232HepG2U2AF2
chr3197583005197583123+intron-Distal3.477099.95507K562RBFOX2
chr3197580682197580752+intron-Distal3.087284.05930HepG2QKI
chr3197606025197606116+intron-Distal3.216083.20331K562CSTF2T
chr3197547717197547794+intron-Distal4.221093.87294K562TARDBP
chr3197589052197589175+intron-Distal4.237825.25941HepG2HNRNPC
chr3197556551197556720+intron-Distal,intron-Proximal3.269846.60947K562KHSRP
chr3197565977197566040+intron-Distal3.950013.66668K562KHSRP
chr3197582684197582750+intron-Distal4.601685.57507HepG2HNRNPL
chr3197580988197581071+intron-Distal4.562056.56329K562U2AF2
chr3197576400197576456+intron-Distal3.904097.41217HepG2QKI
chr3197575542197575619+intron-Distal3.9550310.16833K562KHSRP
chr3197583940197584041+intron-Distal4.456356.18384K562HNRNPL
chr3197575716197575744+intron-Distal4.619365.85485K562KHSRP
chr3197574941197574985+intron-Proximal3.176913.20886K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LRCH3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LRCH3 is not available on ENCORE database.

  • 47 RBPs can affect the levels of LRCH3.  








The Knockdown/knockout RNA-Seq assay for LRCH3 is not available on ENCORE database.





47 RBPs can affect the gene expression of LRCH3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LRCH3ENSG00000186001.8689.19560858.22160-0.316402.641501.64840HepG2YBX3
LRCH3ENSG00000186001.81446.475001022.951900.499702.278701.39430HepG2DDX59
LRCH3ENSG00000186001.8701.75140835.26720-0.251302.283901.67890HepG2DNAJC2
LRCH3ENSG00000186001.81060.22010841.801400.332701.930601.42520HepG2EIF2S1
LRCH3ENSG00000186001.81402.526801179.290900.250002.227301.46200HepG2EIF4G1
LRCH3ENSG00000186001.8886.16250616.416400.523604.796303.77630HepG2FUBP3
LRCH3ENSG00000186001.8800.852101021.17530-0.350601.990501.44160HepG2GPKOW
LRCH3ENSG00000186001.81291.04650881.668100.550105.417304.46420HepG2HNRNPK
LRCH3ENSG00000186001.8863.685101089.08140-0.334504.473403.63240HepG2HNRNPL
LRCH3ENSG00000186001.81222.94790974.524700.327502.135101.57470HepG2HNRNPLL
LRCH3ENSG00000186001.8724.66160940.08280-0.375504.250703.51200HepG2HNRNPU
LRCH3ENSG00000186001.81185.86470885.058700.422003.003602.30460HepG2IGF2BP2
LRCH3ENSG00000186001.81005.002001185.46270-0.238302.034601.37810HepG2NOL12
LRCH3ENSG00000186001.8685.65450838.47890-0.290302.295601.61710HepG2PPIL4
LRCH3ENSG00000186001.81127.80500937.232300.266902.418501.68950HepG2PRPF4
LRCH3ENSG00000186001.81196.89790918.506000.381804.716104.04400HepG2PTBP1
LRCH3ENSG00000186001.8780.381501131.57620-0.536105.944205.11450HepG2PUF60
LRCH3ENSG00000186001.81182.64380994.675700.249601.979601.43730HepG2QKI
LRCH3ENSG00000186001.81251.753001488.74650-0.250102.165601.39430HepG2RBM15
LRCH3ENSG00000186001.81223.05870902.765800.438004.419903.58370HepG2RBM25
LRCH3ENSG00000186001.81197.514501022.174300.228302.018901.54110HepG2NELFE
LRCH3ENSG00000186001.81114.80710952.079400.227501.980701.44700HepG2RECQL
LRCH3ENSG00000186001.8692.86040837.18580-0.273002.403401.79650HepG2SAFB2
LRCH3ENSG00000186001.81470.78960964.597700.608507.081405.99700HepG2SF3B1
LRCH3ENSG00000186001.81136.71100956.208500.249402.267501.72550HepG2SF3B4
LRCH3ENSG00000186001.8769.18960976.30080-0.344004.048303.29460HepG2SMN1
LRCH3ENSG00000186001.81822.367201424.182900.355605.522904.88190HepG2SRFBP1
LRCH3ENSG00000186001.81132.71290812.038000.480107.483206.65620HepG2SRSF9
LRCH3ENSG00000186001.81014.73050824.333600.299702.351601.57900HepG2TIA1
LRCH3ENSG00000186001.8648.67990913.46890-0.493805.108404.47200HepG2TIAL1
LRCH3ENSG00000186001.8632.18780921.63170-0.543807.748606.88260HepG2TRIM56
LRCH3ENSG00000186001.81308.664101049.121500.318802.246901.67510HepG2U2AF1
LRCH3ENSG00000186001.81141.657501385.04150-0.278802.018801.45920K562AKAP8L
LRCH3ENSG00000186001.81227.332301453.21030-0.243702.220801.41090K562ATP5C1
LRCH3ENSG00000186001.8537.70920736.25570-0.453404.711002.97440K562DDX27
LRCH3ENSG00000186001.81259.720201490.50910-0.242702.282501.49700K562DKC1
LRCH3ENSG00000186001.8863.34850649.677100.410102.659701.55770K562FKBP4
LRCH3ENSG00000186001.81014.370901420.75170-0.486105.140304.10660K562GRSF1
LRCH3ENSG00000186001.8693.57690964.83760-0.476203.313002.28610K562HNRNPM
LRCH3ENSG00000186001.81153.432301590.32770-0.463404.405403.40840K562HSPD1
LRCH3ENSG00000186001.8791.04500976.21130-0.303402.190401.43730K562MAGOH
LRCH3ENSG00000186001.8523.86370745.29250-0.508603.489002.00190K562NONO
LRCH3ENSG00000186001.81488.849201113.268400.419303.063202.18830K562PCBP3
LRCH3ENSG00000186001.81082.43350853.896000.342002.944202.11670K562POLR2G
LRCH3ENSG00000186001.8951.619401331.62740-0.484704.528203.44220K562PPIG
LRCH3ENSG00000186001.81207.75660948.425600.348603.138702.43590K562PTBP1
LRCH3ENSG00000186001.81063.651601373.70130-0.369003.071802.50480K562PUS1
LRCH3ENSG00000186001.81028.173101338.36540-0.380404.207003.49200K562RBM15
LRCH3ENSG00000186001.8962.80380772.066300.318402.541001.77090K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LRCH3 is not available on ENCORE database.





21 RBPs can affect the splicing of LRCH3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.213000.000010.01152includedK562IGF2BP2
SELRCH3ENSG00000186001.8chr3+1975568341975569581975564341975565441975576401975577340.155000.001810.03373includedK562SRSF1
SELRCH3ENSG00000186001.8chr3+1976002191976004321975981951975983331976025681976026460.255000.000030.00117includedK562SF3B4
SELRCH3ENSG00000186001.8chr3+197585704197585776197581262197581316197592293197592342-0.323000.000930.01919excludedHepG2U2AF1
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.365000.000000.00000includedK562AKAP8L
SELRCH3ENSG00000186001.8chr3+197585704197585776197581262197581316197592293197592342-0.322000.000350.03921excludedHepG2DDX59
SELRCH3ENSG00000186001.8chr3+1975471951975473011975180961975184111975537481975538850.060000.007620.07364includedHepG2U2AF2
SELRCH3ENSG00000186001.8chr3+1975568341975569581975564341975565441975576401975577340.104000.013000.09996includedK562AQR
SELRCH3ENSG00000186001.8chr3+197547195197547301197518096197518411197553748197553885-0.149000.009420.07740excludedK562AQR
SELRCH3ENSG00000186001.8chr3+197558830197558927197557640197557734197559067197559188-0.161000.001820.06230excludedK562FXR1
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.250000.000020.00055includedK562PUS1
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.102000.000320.06040includedK562MTPAP
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.151000.000000.00241includedK562NSUN2
SELRCH3ENSG00000186001.8chr3+1975588301975589331975576401975577341975590671975591880.106000.000320.09751includedK562KHSRP
SELRCH3ENSG00000186001.8chr3+1975857041975857761975812621975813161975922931975923420.470000.000320.02095includedHepG2PTBP1
SELRCH3ENSG00000186001.8chr3+1975857041975857761975812621975813161975922931975923420.344000.002480.08249includedHepG2MATR3
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.187000.001930.03852includedK562U2AF1
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.149000.000650.09904includedK562SBDS
SELRCH3ENSG00000186001.8chr3+1975857041975857761975812621975813161975922931975923420.439000.001960.04339includedHepG2SRSF1
SELRCH3ENSG00000186001.8chr3+1975568341975569581975564341975565441975576401975577340.110000.000610.01718includedHepG2SRSF1
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.298000.000000.00007includedK562UTP18
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.381000.000000.00001includedK562RBM15
SELRCH3ENSG00000186001.8chr3+1975588301975589271975576401975577341975590671975591880.538000.000340.01181includedK562AGGF1
SELRCH3ENSG00000186001.8chr3+1976073821976076281976025681976026461976104111976153070.266000.000000.00027includedK562PTBP1
SELRCH3ENSG00000186001.8chr3+1975857041975857761975812621975813161975922931975923420.397000.000030.00246includedK562PTBP1
SELRCH3ENSG00000186001.8chr3+1975568341975569441975564341975565441975576401975577340.161000.004560.06471includedK562HNRNPC
A3SSLRCH3ENSG00000186001.8chr3+1975576181975577341975576401975577341975564341975565440.085000.011160.05804longerK562AQR
A3SSLRCH3ENSG00000186001.8chr3+1975981181975983331975981951975983331975970301975971490.072000.000030.00031longerK562AQR
MXELRCH3ENSG00000186001.8chr3+1975929821975930901975970301975971491975922931975923421975981951975983330.154000.006050.062561includedK562DROSHA
MXELRCH3ENSG00000186001.8chr3+1975568341975569441975576401975577341975564341975565441975590671975591880.093000.000630.006111includedK562AQR
MXELRCH3ENSG00000186001.8chr3+1975568341975569441975576181975577341975564341975565441975590671975591880.138000.000610.005941includedK562AQR
MXELRCH3ENSG00000186001.8chr3+1975812621975813161975857041975857761975794311975794911975922931975923420.189000.005820.034291includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LRCH3 is not avaliable on ENCORE database.