GFM2

General Information

Gene Name       : GFM2
Gene ID             : ENSG00000164347.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GFM2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GFM2ENSG00000164347.1724.0720.5322.30ENCSR000AEF
HepG2GFM2ENSG00000164347.1715.3825.4320.41ENCSR985KAT
K562GFM2ENSG00000164347.1732.7535.3334.04ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GFM2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GFM2 RNA is bound by 10 proteins.  







eCLIP assay for GFM2 is not avaliable on ENCORE database.





10 proteins are bound to GFM2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr57401723374017250-3'-UTR,intron-Distal3.813853.25175K562YBX3
chr57401722974017284-3'-UTR,intron-Distal5.633479.21129HepG2SUB1
chr57401714874017212-3'-UTR,intron-Distal3.952197.38140HepG2SUB1
chr57403245774032515-3'-UTR,intron-Distal,intron-Proximal,polyA_site3.855033.71397K562KHSRP
chr57406278274062890-5'-UTR,intron-Distal,intron-Proximal3.290257.75835K562DDX3X
chr57403409774034168-CDS,intron-Distal,intron-Proximal4.308094.75425K562EFTUD2
chr57404357474043624-CDS,intron-Distal,intron-Proximal3.838776.98930HepG2U2AF2
chr57403736774037387-CDS,intron-Distal4.422593.45943HepG2BCLAF1
chr57403413574034191-CDS,intron-Distal,intron-Proximal3.241304.61799HepG2BCLAF1
chr57404728074047314-CDS,intron-Distal4.554104.78529HepG2BCLAF1
chr57403414274034173-CDS,intron-Distal,intron-Proximal3.306604.31744K562YBX3
chr57404151174041602-CDS,intron-Distal4.851884.90367K562ZNF622
chr57403274774032810-CDS,intron-Distal,intron-Proximal3.372516.40723K562YBX3
chr57403301474033117-intron-Distal3.9039910.80633K562KHSRP
chr57405210274052157-intron-Distal4.097303.01445K562EXOSC5
chr57404071574040762-intron-Distal4.477585.91698K562KHSRP
chr57403293574033014-intron-Distal3.655484.72639K562KHSRP
chr57405087574050925-intron-Distal4.249733.01445K562EXOSC5
chr57404863174048714-intron-Distal4.384933.53404K562HNRNPM
chr57403744974037563-intron-Distal,intron-Proximal4.431834.79379K562KHSRP
chr57404076274040815-intron-Distal4.894458.72817K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GFM2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GFM2 is not available on ENCORE database.

  • 82 RBPs can affect the levels of GFM2.  








The Knockdown/knockout RNA-Seq assay for GFM2 is not available on ENCORE database.





82 RBPs can affect the gene expression of GFM2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GFM2ENSG00000164347.13929.71680759.810200.291102.836502.22210HepG2ACO1
GFM2ENSG00000164347.131530.695501181.094100.374001.934801.48110HepG2AKAP1
GFM2ENSG00000164347.131210.31560876.300300.465804.289703.56330HepG2BOP1
GFM2ENSG00000164347.131055.10250851.805300.308702.285501.57910HepG2CALR
GFM2ENSG00000164347.13841.55220598.296800.492102.355301.65340HepG2CNOT7
GFM2ENSG00000164347.13617.02180804.49760-0.382802.346901.70690HepG2CPSF6
GFM2ENSG00000164347.13600.22180455.237400.398802.817401.73290HepG2CSTF2
GFM2ENSG00000164347.13837.460501092.37400-0.383405.096104.13520HepG2DAZAP1
GFM2ENSG00000164347.13946.56680724.396900.385802.597001.84470HepG2DDX55
GFM2ENSG00000164347.13538.47590726.96580-0.433004.187203.38830HepG2DKC1
GFM2ENSG00000164347.13556.55310934.43530-0.747603.181302.54740HepG2EIF2S1
GFM2ENSG00000164347.13594.089501032.82310-0.797803.441802.73010HepG2EIF4A3
GFM2ENSG00000164347.131592.165201303.735800.288203.241502.59930HepG2ETF1
GFM2ENSG00000164347.13585.02500742.58500-0.344102.258601.50450HepG2EWSR1
GFM2ENSG00000164347.13386.11150708.11240-0.875009.794408.68860HepG2HNRNPA1
GFM2ENSG00000164347.13290.80060787.64650-1.4375023.3878021.59870HepG2HNRNPC
GFM2ENSG00000164347.13715.66140918.57300-0.360103.343502.56060HepG2HNRNPF
GFM2ENSG00000164347.13685.40790978.04580-0.512902.143201.52330HepG2HNRNPK
GFM2ENSG00000164347.13445.13880609.21220-0.452702.860701.89430HepG2HNRNPM
GFM2ENSG00000164347.13538.48400782.43890-0.539106.776705.86590HepG2HNRNPU
GFM2ENSG00000164347.13537.16580982.49810-0.871103.951003.15830HepG2IGF2BP2
GFM2ENSG00000164347.13648.99860799.23500-0.300403.298202.50410HepG2ILF2
GFM2ENSG00000164347.13852.432301198.76120-0.491903.179002.28630HepG2LARP4
GFM2ENSG00000164347.13501.285601047.85710-1.063705.013304.18630HepG2MATR3
GFM2ENSG00000164347.13649.95320887.57180-0.449502.214201.35390HepG2MTPAP
GFM2ENSG00000164347.13513.234301072.60500-1.063405.357404.49050HepG2NCBP2
GFM2ENSG00000164347.13780.093801083.19880-0.473605.328204.27630HepG2NOL12
GFM2ENSG00000164347.13700.86420900.42340-0.361503.886103.19260HepG2PCBP1
GFM2ENSG00000164347.13560.35530697.87260-0.316602.395601.70580HepG2PPIL4
GFM2ENSG00000164347.13782.09960559.039200.484303.765202.84090HepG2PRPF8
GFM2ENSG00000164347.13487.209501034.02350-1.0857018.3344016.97880HepG2PUF60
GFM2ENSG00000164347.13873.265801096.86660-0.328902.695502.03340HepG2PUM2
GFM2ENSG00000164347.131197.07570702.313300.769204.754003.84400HepG2RAVER1
GFM2ENSG00000164347.131412.792701089.682300.374504.279403.67140HepG2RBM22
GFM2ENSG00000164347.13810.114101019.64370-0.331903.347002.76410HepG2NELFE
GFM2ENSG00000164347.13704.23790949.57920-0.431204.342203.59330HepG2RECQL
GFM2ENSG00000164347.13412.87940689.84330-0.740504.693603.47660HepG2RPS10
GFM2ENSG00000164347.13670.28350501.434300.418602.650101.73120HepG2SERBP1
GFM2ENSG00000164347.13561.39570861.45010-0.617705.694904.71260HepG2SF3B1
GFM2ENSG00000164347.131427.64080958.510800.574703.465102.58610HepG2SNRNP70
GFM2ENSG00000164347.131508.689501230.756700.293703.411702.87290HepG2SRFBP1
GFM2ENSG00000164347.13677.597901020.96920-0.591408.921707.88270HepG2SRSF5
GFM2ENSG00000164347.13685.74300902.43660-0.396204.022403.20780HepG2SRSF7
GFM2ENSG00000164347.13973.758101161.10470-0.253902.505001.90790HepG2SUCLG1
GFM2ENSG00000164347.131112.77670894.834600.314402.774402.21340HepG2TAF15
GFM2ENSG00000164347.13624.35460767.08260-0.297002.650502.09540HepG2TRIM56
GFM2ENSG00000164347.131707.452602510.03950-0.555906.989006.12590K562AQR
GFM2ENSG00000164347.131073.636101378.52420-0.360604.617603.36050K562BCLAF1
GFM2ENSG00000164347.131795.432002177.73200-0.278503.242202.03830K562CPEB4
GFM2ENSG00000164347.13947.769401443.26090-0.606708.393807.01580K562CPSF6
GFM2ENSG00000164347.13818.651901045.81590-0.353303.261102.10070K562CSTF2
GFM2ENSG00000164347.131812.060802253.23290-0.314404.454303.65410K562DDX47
GFM2ENSG00000164347.13728.178301089.27080-0.581005.314104.02600K562EFTUD2
GFM2ENSG00000164347.131169.983301736.31000-0.5695010.254409.00460K562EIF2S2
GFM2ENSG00000164347.13775.517001166.45940-0.588904.494503.13910K562EIF3D
GFM2ENSG00000164347.131012.126001254.95050-0.310202.835102.02950K562EIF3G
GFM2ENSG00000164347.13865.328901209.44280-0.483004.747003.67210K562EIF4A3
GFM2ENSG00000164347.13884.402801089.15900-0.300402.661201.53750K562EIF4B
GFM2ENSG00000164347.131146.336301468.51520-0.357302.713201.86810K562FMR1
GFM2ENSG00000164347.13934.294601244.71280-0.413903.053102.08750K562FTO
GFM2ENSG00000164347.131757.281701370.915200.358102.053301.45740K562G3BP2
GFM2ENSG00000164347.13967.850101377.94600-0.509705.395404.29240K562GPKOW
GFM2ENSG00000164347.131716.176102313.92200-0.431104.993103.97920K562GRSF1
GFM2ENSG00000164347.131013.306401669.43620-0.7203012.1375010.12910K562HNRNPA1
GFM2ENSG00000164347.13470.812001339.92800-1.5089025.5272023.79250K562HNRNPC
GFM2ENSG00000164347.131626.905902036.36000-0.323903.027901.91710K562HNRNPL
GFM2ENSG00000164347.131074.731001404.17780-0.385702.633001.72720K562HNRNPM
GFM2ENSG00000164347.131568.977301848.73140-0.236702.206901.41060K562HNRNPU
GFM2ENSG00000164347.131240.120001669.72690-0.429102.993001.91210K562IGF2BP2
GFM2ENSG00000164347.131091.420201751.81780-0.6826010.972209.02680K562MATR3
GFM2ENSG00000164347.13999.428901345.03450-0.428504.229403.13230K562METAP2
GFM2ENSG00000164347.131322.517901684.37970-0.348905.148304.06890K562MTPAP
GFM2ENSG00000164347.13825.560801207.71540-0.548806.845004.95060K562NCBP2
GFM2ENSG00000164347.131513.005901871.56550-0.306805.498104.50050K562NSUN2
GFM2ENSG00000164347.131136.426501561.87550-0.458804.715203.43080K562PCBP2
GFM2ENSG00000164347.13841.969001201.33440-0.512802.875101.95040K562PSIP1
GFM2ENSG00000164347.132471.134603409.19980-0.464305.649304.48630K562PUF60
GFM2ENSG00000164347.132745.630503552.96900-0.371906.198904.74420K562PUM2
GFM2ENSG00000164347.132135.057101635.924700.384103.483902.88550K562PUS1
GFM2ENSG00000164347.131882.925701593.882600.240302.180801.64390K562RBM15
GFM2ENSG00000164347.131226.229101635.49520-0.415503.903702.89290K562RBM22
GFM2ENSG00000164347.131238.566401594.09200-0.364102.738201.37000K562RBM34
GFM2ENSG00000164347.13839.957401095.81430-0.383602.947801.92300K562RCC2
GFM2ENSG00000164347.13927.250701236.02830-0.414705.744303.48290K562RPS10
GFM2ENSG00000164347.131415.618201846.65570-0.383505.505504.38300K562SF3A3
GFM2ENSG00000164347.13858.613301310.52300-0.610105.471004.07240K562SF3B1
GFM2ENSG00000164347.13992.377301426.51690-0.523504.374803.29040K562SF3B4
GFM2ENSG00000164347.13796.963701038.82830-0.382402.200101.30610K562SRFBP1
GFM2ENSG00000164347.131610.984101891.92950-0.231902.980502.01510K562SRPK2
GFM2ENSG00000164347.13810.308901671.75880-1.0448022.8903020.84830K562SRSF1
GFM2ENSG00000164347.131211.815501578.71490-0.381602.983001.88530K562SRSF5
GFM2ENSG00000164347.13717.366301026.52490-0.517003.719002.52420K562SUPV3L1
GFM2ENSG00000164347.131026.423301692.04690-0.721109.445208.02280K562TARDBP
GFM2ENSG00000164347.131146.658601632.13930-0.509306.475805.14580K562TIA1
GFM2ENSG00000164347.13945.063001227.30650-0.377003.054002.05010K562TRIM56
GFM2ENSG00000164347.13900.728001373.22400-0.608406.257405.05690K562U2AF2
GFM2ENSG00000164347.131569.435501984.45520-0.338505.320904.35910K562UPF1
GFM2ENSG00000164347.131429.504601932.45500-0.434903.340202.01630K562UTP3
GFM2ENSG00000164347.131445.829001765.70850-0.288404.090103.07610K562WDR43
GFM2ENSG00000164347.132276.311202974.05500-0.385704.401802.76490K562WRN
GFM2ENSG00000164347.132329.093902827.58360-0.279802.356001.56930K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GFM2 is not available on ENCORE database.





17 RBPs can affect the splicing of GFM2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGFM2ENSG00000164347.13chr5-7404308974043217740419297404199074043516740436050.098000.000000.00002includedK562SRSF1
SEGFM2ENSG00000164347.13chr5-7402642674026600740260847402622374028846740289230.302000.000000.00000includedK562SRSF1
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674029213-0.093000.004280.06698excludedK562SRSF1
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.127000.000550.01273excludedK562SRSF1
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.202000.000010.00027excludedK562SF3B4
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.138000.002530.07397excludedK562PRPF8
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674029213-0.067000.001970.05288excludedK562AKAP8L
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.163000.000250.00860excludedHepG2HNRNPK
SEGFM2ENSG00000164347.13chr5-740214647402158074018203740183867402176574022008-0.131000.000000.00000excludedK562AQR
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674028945-0.189000.000000.00000excludedK562AQR
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374036038-0.239000.000000.00000excludedK562AQR
SEGFM2ENSG00000164347.13chr5-740551937405525174054673740547717405672674056858-0.052000.000290.00431excludedK562AQR
SEGFM2ENSG00000164347.13chr5-740419297404199074041502740416827404351674043635-0.052000.000330.00474excludedK562AQR
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.107000.002590.08019excludedK562FXR1
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674029213-0.054000.007610.08534excludedK562PUS1
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.152000.001440.07295excludedHepG2NCBP2
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674029213-0.130000.000220.02016excludedHepG2HNRNPL
SEGFM2ENSG00000164347.13chr5-7402642674026600740260847402622374028846740289230.089000.000010.00064includedHepG2SRSF1
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674028923-0.204000.000020.00127excludedHepG2SF3A3
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.149000.000340.01290excludedHepG2SF3A3
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.136000.000180.03157excludedK562RBM22
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674028923-0.073000.002160.06053excludedK562UTP18
SEGFM2ENSG00000164347.13chr5-740419297404199074041502740416827404351674043605-0.104000.005510.07832excludedK562U2AF2
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.217000.000000.00001excludedK562HNRNPK
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674029213-0.252000.000060.00417excludedHepG2HNRNPC
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.200000.000000.00004excludedK562PTBP1
SEGFM2ENSG00000164347.13chr5-740260847402622374021765740219517402884674029213-0.229000.000000.00000excludedK562HNRNPC
SEGFM2ENSG00000164347.13chr5-740343267403446774034142740342427403581374035962-0.097000.000840.01666excludedK562HNRNPC
A3SSGFM2ENSG00000164347.13chr5-7402176574022008740217657402195174028846740289230.294000.000400.00306longerK562AQR
A3SSGFM2ENSG00000164347.13chr5-7404351674043635740435167404360574046403740464920.052000.000040.00038longerK562AQR
A3SSGFM2ENSG00000164347.13chr5-7405672674056858740567267405681174059504740596210.103000.000010.00006longerK562AQR
A3SSGFM2ENSG00000164347.13chr5-7402884274028945740288427402892374032620740328630.171000.000000.00000longerK562AQR
A3SSGFM2ENSG00000164347.13chr5-7405467374054872740546737405477174055193740552510.066000.000000.00000longerK562AQR
A3SSGFM2ENSG00000164347.13chr5-7404640374046522740464037404649274047192740473180.082000.000100.00085longerK562AQR
A3SSGFM2ENSG00000164347.13chr5-7403262074032863740326207403281074034142740342420.159000.000000.00000longerK562AQR
MXEGFM2ENSG00000164347.13chr5-7404719274047318740546737405477174043516740436057405519374055251-0.054000.003100.051002includedHepG2U2AF1
MXEGFM2ENSG00000164347.13chr5-74026084740262237402642674026600740217657402195174028846740289230.077000.000050.001811includedHepG2SRSF1
MXEGFM2ENSG00000164347.13chr5-74026084740262237402642674026600740217657402195174028846740289230.154000.000000.000001includedK562SRSF1
MXEGFM2ENSG00000164347.13chr5-74047192740473187405467374054771740464037404649274056726740568110.064000.000360.003721includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GFM2 is not avaliable on ENCORE database.