EXOSC7

General Information

Gene Name       : EXOSC7
Gene ID             : ENSG00000075914.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EXOSC7)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXOSC7ENSG00000075914.1229.2139.4834.34ENCSR000AEF
HepG2EXOSC7ENSG00000075914.1268.6448.0558.34ENCSR985KAT
K562EXOSC7ENSG00000075914.1271.6459.5565.59ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXOSC7 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXOSC7 RNA is bound by 14 proteins.  







eCLIP assay for EXOSC7 is not avaliable on ENCORE database.





14 proteins are bound to EXOSC7 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr34505285345052925+3'-UTR,intron-Distal,intron-Proximal6.0371511.21418HepG2SUB1
chr34505289845052949+3'-UTR,intron-Distal,intron-Proximal5.263128.81987K562TIA1
chr34505287745052960+3'-UTR,intron-Distal,intron-Proximal5.3312522.08556K562PUM2
chr34504900445049095+CDS,intron-Distal,intron-Proximal3.258643.99124HepG2PPIG
chr34501780745017827+CDS,intron-Distal,intron-Proximal3.437635.11648K562DDX3X
chr34503063145030734+CDS,intron-Distal,intron-Proximal3.2120216.66599K562DDX3X
chr34503857645038655+CDS,intron-Proximal3.912709.27186HepG2PPIG
chr34505266245052750+CDS,intron-Distal,intron-Proximal4.069204.69223K562SF3B4
chr34501780645017883+CDS,intron-Distal,intron-Proximal4.384437.44508K562PRPF8
chr34501780245017867+CDS,intron-Distal,intron-Proximal5.4486317.12423HepG2PRPF8
chr34503065845030728+CDS,intron-Distal4.759964.66187HepG2SUB1
chr34504673845046816+CDS,intron-Distal,intron-Proximal5.053197.86715HepG2SF3A3
chr34503111145031136+CDS,intron-Distal4.966166.46301HepG2PPIG
chr34504306845043177+CDS,intron-Distal,intron-Proximal4.818447.46483HepG2PRPF8
chr34503872745038781+CDS,intron-Proximal5.411557.36776HepG2PRPF8
chr34504301045043065+CDS,intron-Distal,intron-Proximal4.610345.13577HepG2U2AF2
chr34504891345048983+CDS,intron-Distal3.069893.29600K562LIN28B
chr34504673645046829+CDS,intron-Distal,intron-Proximal4.8883415.70758K562SF3B4
chr34503630345036373+intron-Distal4.772214.19739K562EIF4G2
chr34504483645044933+intron-Distal4.3734014.32599K562TARDBP
chr34501788345017929+intron-Distal,intron-Proximal4.160703.49003K562PRPF8
chr34504403845044117+intron-Distal3.608164.76004K562KHSRP
chr34503097845031034+intron-Distal,intron-Proximal5.276727.41223K562SF3B4
chr34504907445049115+intron-Distal,intron-Proximal5.540076.83960K562AQR
chr34504906745049074+intron-Distal,intron-Proximal4.331154.89208K562AQR
chr34504508745045154+intron-Distal4.470284.12401HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXOSC7 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXOSC7 is not available on ENCORE database.

  • 75 RBPs can affect the levels of EXOSC7.  








The Knockdown/knockout RNA-Seq assay for EXOSC7 is not available on ENCORE database.





75 RBPs can affect the gene expression of EXOSC7 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXOSC7ENSG00000075914.8446.80900557.30840-0.318802.247601.54870HepG2AKAP8L
EXOSC7ENSG00000075914.8257.39310363.92460-0.499702.742401.51520HepG2BUD13
EXOSC7ENSG00000075914.8217.44370343.84760-0.661104.139102.85500HepG2CSTF2
EXOSC7ENSG00000075914.8541.08360775.52130-0.519305.661104.80430HepG2CELF1
EXOSC7ENSG00000075914.8337.78270485.26110-0.522703.506002.75030HepG2DDX21
EXOSC7ENSG00000075914.8366.14390475.08910-0.375802.114201.32690HepG2DDX24
EXOSC7ENSG00000075914.8685.33960883.97420-0.367202.148501.59060HepG2DDX3X
EXOSC7ENSG00000075914.8340.08580547.33850-0.686504.506103.54410HepG2DDX55
EXOSC7ENSG00000075914.8365.37300530.70330-0.538504.862304.01070HepG2DKC1
EXOSC7ENSG00000075914.8531.46170729.97910-0.457902.948902.33650HepG2EIF2S1
EXOSC7ENSG00000075914.8544.08070806.64250-0.568104.103903.32930HepG2EIF4A3
EXOSC7ENSG00000075914.8828.053301155.83100-0.481107.125806.23560HepG2ETF1
EXOSC7ENSG00000075914.8342.35800490.41310-0.518502.284301.58190HepG2FIP1L1
EXOSC7ENSG00000075914.8501.26570755.06770-0.591004.414703.58260HepG2G3BP1
EXOSC7ENSG00000075914.8600.20700801.74710-0.417702.690401.81440HepG2G3BP2
EXOSC7ENSG00000075914.8162.06920286.10670-0.819904.754603.57840HepG2GEMIN5
EXOSC7ENSG00000075914.8384.68630502.23710-0.384702.218901.31180HepG2GNB2L1
EXOSC7ENSG00000075914.8269.54430371.15410-0.461502.267401.67780HepG2HNRNPA1
EXOSC7ENSG00000075914.8133.58220262.13540-0.972605.610204.74640HepG2HNRNPLL
EXOSC7ENSG00000075914.8576.79270767.47000-0.412102.481801.83840HepG2IGF2BP2
EXOSC7ENSG00000075914.8518.63310772.01800-0.573903.501002.35670HepG2KHSRP
EXOSC7ENSG00000075914.8577.81860814.36600-0.495103.453802.71960HepG2MAGOH
EXOSC7ENSG00000075914.8528.44860838.15070-0.665405.554104.67110HepG2NCBP2
EXOSC7ENSG00000075914.8311.87860502.61970-0.688502.879701.76240HepG2NONO
EXOSC7ENSG00000075914.8397.72590746.29890-0.908009.384808.07340HepG2PABPC4
EXOSC7ENSG00000075914.8489.01420749.62130-0.616307.908906.96760HepG2PCBP1
EXOSC7ENSG00000075914.8468.97120762.80130-0.701809.509408.61570HepG2PTBP1
EXOSC7ENSG00000075914.8670.50650837.88350-0.321502.849402.24990HepG2PUM1
EXOSC7ENSG00000075914.8426.51080565.00490-0.405703.530802.85360HepG2PUS1
EXOSC7ENSG00000075914.8723.37520966.05950-0.417404.206903.60260HepG2RBM22
EXOSC7ENSG00000075914.8511.60300749.73050-0.551304.985104.10370HepG2RBM25
EXOSC7ENSG00000075914.8513.58760848.89670-0.7250010.248309.32840HepG2NELFE
EXOSC7ENSG00000075914.8564.52650790.68260-0.486105.155404.34810HepG2RECQL
EXOSC7ENSG00000075914.8384.01710516.34310-0.427202.296101.66550HepG2RPLP0
EXOSC7ENSG00000075914.8191.03320312.66140-0.710804.619203.84680HepG2RPS19
EXOSC7ENSG00000075914.8402.27440547.27980-0.444102.844402.03360HepG2RPS2
EXOSC7ENSG00000075914.8417.34440664.90810-0.671904.386803.37910HepG2RPS3A
EXOSC7ENSG00000075914.8473.66480365.227700.375002.481201.86520HepG2SAFB2
EXOSC7ENSG00000075914.8629.37610794.11440-0.335402.780002.18700HepG2SF3B4
EXOSC7ENSG00000075914.8777.253301091.12630-0.489406.703006.01760HepG2SRFBP1
EXOSC7ENSG00000075914.8566.99530828.90810-0.547906.468705.81920HepG2SRSF1
EXOSC7ENSG00000075914.8337.73830470.95110-0.479703.609602.83030HepG2SRSF7
EXOSC7ENSG00000075914.8485.04750674.38210-0.475404.972204.27200HepG2SRSF9
EXOSC7ENSG00000075914.8645.68000947.35190-0.553108.078607.29000HepG2SSB
EXOSC7ENSG00000075914.8242.53410544.86090-1.1677010.798809.60740HepG2SUPV3L1
EXOSC7ENSG00000075914.8326.51300541.13630-0.728902.982901.87580HepG2TBRG4
EXOSC7ENSG00000075914.8295.61440398.42710-0.430602.373101.90350HepG2TIAL1
EXOSC7ENSG00000075914.8224.33990378.86340-0.756007.067906.03590HepG2UPF1
EXOSC7ENSG00000075914.8497.93870365.777200.444903.377602.72780HepG2UTP3
EXOSC7ENSG00000075914.8229.74280324.81910-0.499603.315702.59090HepG2ZC3H8
EXOSC7ENSG00000075914.81528.08090920.553500.7310016.9457015.66390K562AGGF1
EXOSC7ENSG00000075914.81264.920501011.602300.322302.646001.69130K562AKAP8
EXOSC7ENSG00000075914.81376.99630957.890700.523505.922804.94320K562AKAP8L
EXOSC7ENSG00000075914.81525.690202092.74520-0.455904.411803.70240K562AQR
EXOSC7ENSG00000075914.81286.901601005.082700.356504.091702.96140K562ATP5C1
EXOSC7ENSG00000075914.8391.59880526.15840-0.426102.362501.56330K562BOP1
EXOSC7ENSG00000075914.8358.89900508.14670-0.501703.454002.24730K562CCAR1
EXOSC7ENSG00000075914.8442.44660559.45480-0.338502.041101.35930K562CPSF6
EXOSC7ENSG00000075914.81556.041801030.676900.5942010.990309.00600K562DKC1
EXOSC7ENSG00000075914.81029.764301554.56670-0.5942010.552309.28700K562EIF2S2
EXOSC7ENSG00000075914.8238.00650516.86600-1.118803.704802.52240K562EIF3A
EXOSC7ENSG00000075914.8815.526801013.05090-0.312902.208601.47220K562EIF4A3
EXOSC7ENSG00000075914.8345.13660569.23680-0.721906.121804.83750K562FMR1
EXOSC7ENSG00000075914.8341.91210482.48160-0.496802.936001.99270K562FTO
EXOSC7ENSG00000075914.8420.55120807.75120-0.9416012.6640011.46340K562HNRNPC
EXOSC7ENSG00000075914.8962.73460645.882200.575804.652403.41600K562HNRNPM
EXOSC7ENSG00000075914.81338.053301016.515500.396404.208803.16220K562KIF1C
EXOSC7ENSG00000075914.8319.22470456.09390-0.514802.384101.52680K562KRR1
EXOSC7ENSG00000075914.81551.674001138.760600.446305.224503.89060K562MBNL1
EXOSC7ENSG00000075914.81922.639702381.56770-0.308802.814801.67410K562MSI2
EXOSC7ENSG00000075914.81176.91180798.192700.560103.118402.17340K562NAA15
EXOSC7ENSG00000075914.8983.694501140.24280-0.213102.065001.40930K562NSUN2
EXOSC7ENSG00000075914.8594.57290899.54150-0.597303.488302.55430K562PCBP3
EXOSC7ENSG00000075914.81170.17690949.871100.300802.053901.57270K562PUS1
EXOSC7ENSG00000075914.81182.81840925.583900.353703.695403.02460K562RBM15
EXOSC7ENSG00000075914.8729.548001089.08210-0.578004.684903.61940K562RPS19
EXOSC7ENSG00000075914.8676.575301035.16410-0.613505.251103.81130K562SUPV3L1
EXOSC7ENSG00000075914.8503.36640696.59120-0.468703.020402.03860K562TIAL1
EXOSC7ENSG00000075914.82275.509802749.02260-0.272702.694201.31290K562UBE2L3
EXOSC7ENSG00000075914.8584.494001095.63120-0.9065011.793309.63480K562UCHL5
EXOSC7ENSG00000075914.8941.732301209.02780-0.360504.373603.49060K562UPF1
EXOSC7ENSG00000075914.8791.507801034.52010-0.386303.351102.39220K562WDR3
EXOSC7ENSG00000075914.8867.839901115.71780-0.362502.486401.35950K562XRN2
EXOSC7ENSG00000075914.81825.645902357.65200-0.368903.675602.65430K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXOSC7 is not available on ENCORE database.





8 RBPs can affect the splicing of EXOSC7 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEXOSC7ENSG00000075914.8chr3+4504333345043506450430294504310045046782450469060.059000.000010.00024includedK562SRSF1
SEEXOSC7ENSG00000075914.8chr3+4501866045018909450177214501782645030631450307340.077000.000000.00003includedHepG2U2AF1
SEEXOSC7ENSG00000075914.8chr3+450310414503113645017721450178264503857845038744-0.088000.000010.00024excludedK562AQR
SEEXOSC7ENSG00000075914.8chr3+4501866045018909450177214501782645030631450307340.189000.000000.00000includedK562U2AF1
SEEXOSC7ENSG00000075914.8chr3+4501866045018909450177214501782645030631450307140.062000.000820.01687includedK562U2AF2
MXEEXOSC7ENSG00000075914.8chr3+4504891145049067450527264505288545046782450469064505367445053745-0.070000.001850.027922includedK562DROSHA
MXEEXOSC7ENSG00000075914.8chr3+45038578450387444504302945043100450177424501782645046782450469060.075000.000010.000111includedK562AQR
MXEEXOSC7ENSG00000075914.8chr3+4504891145049067450527264505288545046782450469064505367445053745-0.214000.000140.007942includedHepG2XRN2
MXEEXOSC7ENSG00000075914.8chr3+4504891145049067450527264505288545046782450469064505367445053745-0.165000.000040.001422includedK562HNRNPC
MXEEXOSC7ENSG00000075914.8chr3+4504891145049067450527264505288545046782450469064505367445053745-0.139000.000330.015582includedHepG2NCBP2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXOSC7 is not avaliable on ENCORE database.