EAF1

General Information

Gene Name       : EAF1
Gene ID             : ENSG00000144597.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: EAF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EAF1ENSG00000144597.1311.7910.9211.36ENCSR000AEF
HepG2EAF1ENSG00000144597.1310.9813.5012.24ENCSR985KAT
K562EAF1ENSG00000144597.1314.9915.1715.08ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EAF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EAF1 RNA is bound by 9 proteins.  







eCLIP assay for EAF1 is not avaliable on ENCORE database.





9 proteins are bound to EAF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr31548363115483689+3'-UTR6.0455716.27819K562TARDBP
chr31548361615483678+3'-UTR4.177056.46185HepG2FUBP3
chr31548196415482003+3'-UTR4.045376.74636K562UPF1
chr31548396815484049+3'-UTR4.184844.48843K562TIA1
chr31548363115483673+3'-UTR4.136677.12652K562UPF1
chr31548382115483879+3'-UTR3.766069.44690K562TARDBP
chr31548215015482197+3'-UTR3.493975.35486K562UPF1
chr31548378215483821+3'-UTR4.056057.30349K562TARDBP
chr31548159415481663+3'-UTR3.724438.52451K562UPF1
chr31548342815483461+3'-UTR3.804665.15345K562UPF1
chr31548371515483782+3'-UTR5.8439714.35493K562TARDBP
chr31548369015483759+3'-UTR3.828194.74394K562EIF4G2
chr31548371615483814+3'-UTR3.049174.17354K562DDX6
chr31548301315483081+3'-UTR3.1052115.10979K562UPF1
chr31548378215483865+3'-UTR3.8228613.56677K562UPF1
chr31548400315484062+3'-UTR3.778043.45805K562KHSRP
chr31548215115482221+3'-UTR4.095203.95192HepG2UPF1
chr31548376815483836+3'-UTR4.146853.98311K562IGF2BP1
chr31548102415481100+3'-UTR4.176469.37691K562UPF1
chr31548113015481184+3'-UTR3.278206.48866K562UPF1
chr31548374115483820+3'-UTR3.302535.68175HepG2FUBP3
chr31546912915469270+5'-UTR3.444813.02345K562ZNF622
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EAF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EAF1 is not available on ENCORE database.

  • 64 RBPs can affect the levels of EAF1.  








The Knockdown/knockout RNA-Seq assay for EAF1 is not available on ENCORE database.





64 RBPs can affect the gene expression of EAF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EAF1ENSG00000144597.9580.951101141.19790-0.9741010.670009.69290HepG2AKAP1
EAF1ENSG00000144597.9454.91000783.19120-0.7838012.6086011.13350HepG2AKAP8L
EAF1ENSG00000144597.91253.44060944.241800.408602.957202.14620HepG2ASCC1
EAF1ENSG00000144597.91025.155701238.09090-0.272302.847902.15330HepG2AUH
EAF1ENSG00000144597.91269.39540791.451200.681508.379407.40670HepG2BOP1
EAF1ENSG00000144597.9497.74030897.09590-0.849909.313907.96750HepG2CIRBP
EAF1ENSG00000144597.9482.79820842.15470-0.802705.315904.25350HepG2CNOT7
EAF1ENSG00000144597.9269.51700726.59640-1.4308021.2185019.54210HepG2CPSF6
EAF1ENSG00000144597.91200.53440942.240600.349403.838603.10310HepG2CELF1
EAF1ENSG00000144597.9537.87520707.83040-0.396103.310102.04560HepG2DDX1
EAF1ENSG00000144597.9864.07130623.447900.470803.883603.09340HepG2DDX21
EAF1ENSG00000144597.9273.79130694.06200-1.3420026.1991024.28660HepG2DNAJC21
EAF1ENSG00000144597.9794.76450588.784400.432703.634302.41620HepG2EIF3G
EAF1ENSG00000144597.9540.96630971.34400-0.844406.784005.73830HepG2EIF4B
EAF1ENSG00000144597.9681.78780957.48320-0.489904.098503.11920HepG2EIF4G2
EAF1ENSG00000144597.9994.19730761.730300.384202.880002.02900HepG2EWSR1
EAF1ENSG00000144597.9487.57780933.74350-0.9374010.453509.20210HepG2G3BP1
EAF1ENSG00000144597.9535.45740823.65670-0.621304.757003.93230HepG2GPKOW
EAF1ENSG00000144597.9921.31570744.246600.307803.037502.01880HepG2HDGF
EAF1ENSG00000144597.9706.04860931.10850-0.399204.210503.09750HepG2HNRNPA2B1
EAF1ENSG00000144597.9343.18800779.42160-1.1834016.8178015.24900HepG2HNRNPC
EAF1ENSG00000144597.9421.82990786.03050-0.897909.677108.57900HepG2HNRNPLL
EAF1ENSG00000144597.9700.77260949.12480-0.437703.104202.39370HepG2IGF2BP2
EAF1ENSG00000144597.9565.93910844.16360-0.576903.524802.11240HepG2KRR1
EAF1ENSG00000144597.91279.264901006.939500.345202.218201.62860HepG2MAGOH
EAF1ENSG00000144597.9732.447401012.57080-0.467203.071402.40970HepG2MATR3
EAF1ENSG00000144597.9927.30070739.508800.326402.510601.73840HepG2MSI2
EAF1ENSG00000144597.9795.784501004.63580-0.336202.967402.17820HepG2NOL12
EAF1ENSG00000144597.91469.88580769.705500.933206.972005.52030HepG2PABPC1
EAF1ENSG00000144597.91214.88220922.981900.396302.719002.00300HepG2PABPC4
EAF1ENSG00000144597.9601.11920766.38070-0.350403.115402.22110HepG2PARN
EAF1ENSG00000144597.9469.18800690.58340-0.557606.054604.99720HepG2PPIL4
EAF1ENSG00000144597.91290.14510919.663300.488305.356804.44700HepG2RBM25
EAF1ENSG00000144597.9853.761201041.29830-0.286502.491001.97310HepG2NELFE
EAF1ENSG00000144597.91161.63210974.117700.253902.278601.73500HepG2SF3B4
EAF1ENSG00000144597.9738.10130919.53540-0.317103.287002.53320HepG2SLBP
EAF1ENSG00000144597.91900.574101341.927400.5020010.567009.75860HepG2SRFBP1
EAF1ENSG00000144597.91667.782301016.785100.7138016.8854015.92710HepG2SRSF1
EAF1ENSG00000144597.9958.64400827.223600.212601.780201.32030HepG2SRSF9
EAF1ENSG00000144597.9605.667701076.86580-0.8302018.7438017.35740HepG2SUCLG1
EAF1ENSG00000144597.9716.70980913.97370-0.350803.027702.44490HepG2TAF15
EAF1ENSG00000144597.9415.60150744.92910-0.841906.113503.97710HepG2TRA2A
EAF1ENSG00000144597.9542.85610759.07360-0.483705.631904.87980HepG2TRIM56
EAF1ENSG00000144597.91310.48730781.524900.745609.166508.01530HepG2U2AF1
EAF1ENSG00000144597.9324.57610477.08730-0.555702.158801.48800HepG2UCHL5
EAF1ENSG00000144597.91334.83390800.180600.7382016.0864014.81740HepG2UTP3
EAF1ENSG00000144597.9506.02020711.02310-0.490705.805304.88790HepG2ZC3H8
EAF1ENSG00000144597.91268.23130911.529000.476408.689807.85980HepG2ZNF622
EAF1ENSG00000144597.91275.269001539.09550-0.271303.033702.44330K562AGGF1
EAF1ENSG00000144597.91026.594801601.47960-0.641508.496307.28940K562AKAP8L
EAF1ENSG00000144597.96618.517401708.086901.9540082.9269080.15420K562AQR
EAF1ENSG00000144597.92323.630101616.448700.5235011.141809.93120K562DDX47
EAF1ENSG00000144597.91085.20230893.347600.280602.199801.48450K562EIF3G
EAF1ENSG00000144597.91484.513701013.957600.549909.279308.24640K562FXR1
EAF1ENSG00000144597.91194.62310897.022200.413202.354701.71020K562G3BP2
EAF1ENSG00000144597.9778.10710970.68110-0.319002.223001.51070K562GPKOW
EAF1ENSG00000144597.9617.24690899.93770-0.544005.284204.48420K562HNRNPC
EAF1ENSG00000144597.9945.555801214.22140-0.360803.197102.20000K562MATR3
EAF1ENSG00000144597.91549.378901044.839100.568302.351701.45380K562PABPN1
EAF1ENSG00000144597.91436.003401082.545800.407503.647402.52590K562PCBP2
EAF1ENSG00000144597.91996.72430900.527701.1487022.6277020.46840K562PRPF8
EAF1ENSG00000144597.93252.613502267.150300.520607.211005.89010K562PUF60
EAF1ENSG00000144597.92005.763501588.364800.336502.827702.27980K562PUS1
EAF1ENSG00000144597.91404.117801133.435800.308902.297401.53620K562RBM22
EAF1ENSG00000144597.9546.07370736.30960-0.431203.470202.36430K562RCC2
EAF1ENSG00000144597.91496.78320917.379100.706207.269905.93190K562RPS19
EAF1ENSG00000144597.91078.862201356.99320-0.330903.553502.63710K562SF3A3
EAF1ENSG00000144597.91280.88450932.814600.457405.330404.11860K562SF3B4
EAF1ENSG00000144597.91698.279801097.342700.630002.534101.38030K562SNRNP200
EAF1ENSG00000144597.91467.586701158.889800.340603.100602.35540K562SRSF1
EAF1ENSG00000144597.91377.735301978.12710-0.521807.714005.40640K562SUCLG1
EAF1ENSG00000144597.91197.67470869.583900.461702.571201.52270K562U2AF1
EAF1ENSG00000144597.91106.42750898.065400.300902.479401.71800K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EAF1 is not available on ENCORE database.





11 RBPs can affect the splicing of EAF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.188000.003490.05611excludedK562SF3B4
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.328000.000000.00000excludedHepG2U2AF1
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.306000.000000.00000excludedK562AKAP8L
SEEAF1ENSG00000144597.9chr3+154735931547373015471380154715141547585415476045-0.158000.000240.00362excludedK562AQR
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.322000.000000.00000excludedK562PUS1
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.358000.000000.00005excludedK562U2AF1
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.201000.000010.00191excludedK562HNRNPL
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.152000.000420.05213excludedHepG2SSB
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.166000.003600.09770excludedK562TARDBP
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.287000.000000.00000excludedK562RBM15
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.377000.000000.00000excludedK562AGGF1
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.318000.000490.02215excludedHepG2HNRNPC
SEEAF1ENSG00000144597.9chr3+154735931547373015471419154715141547585415476045-0.369000.000000.00000excludedK562HNRNPC
A3SSEAF1ENSG00000144597.9chr3+1547356215473730154735931547373015471434154715140.098000.000010.00012longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EAF1 is not avaliable on ENCORE database.