BROX

General Information

Gene Name       : BROX
Gene ID             : ENSG00000162819.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: BROX)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878BROXENSG00000162819.117.455.906.68ENCSR000AEF
HepG2BROXENSG00000162819.115.0910.377.73ENCSR985KAT
K562BROXENSG00000162819.1115.3815.9215.65ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for BROX is not avaliable on ENCORE database.



Proteins bound to RNA
  • BROX RNA is bound by 14 proteins.  







eCLIP assay for BROX is not avaliable on ENCORE database.





14 proteins are bound to BROX RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1222906823222906908+3'-UTR3.236275.92362K562IGF2BP1
chr1222906031222906134+3'-UTR,CDS4.280003.25872K562IGF2BP1
chr1222906433222906481+3'-UTR4.141759.23027K562HNRNPC
chr1222905965222906055+3'-UTR,CDS,intron-Proximal3.149355.39278K562ZNF622
chr1222908159222908228+3'-UTR4.2199910.36810K562PUM2
chr1222905969222906005+3'-UTR,CDS,intron-Proximal4.484024.04372HepG2BCLAF1
chr1222906946222907075+3'-UTR3.515979.55426K562IGF2BP1
chr1222906447222906484+3'-UTR3.822776.12784K562U2AF1
chr1222906435222906447+3'-UTR4.454295.12844K562U2AF1
chr1222885934222886042+5'-UTR4.532708.39621K562DDX3X
chr1222892618222892702+CDS,intron-Proximal3.830424.05694K562IGF2BP1
chr1222898850222898902+CDS,intron-Proximal3.960613.34184HepG2GRWD1
chr1222900583222900599+CDS3.214086.40723K562YBX3
chr1222900509222900566+CDS,intron-Proximal3.021035.01560K562UCHL5
chr1222898838222898897+CDS3.390243.95463K562ZNF800
chr1222902971222903044+CDS,intron-Proximal6.0061037.08756K562LIN28B
chr1222892606222892700+CDS3.242565.75243K562ZNF622
chr1222900508222900556+CDS,intron-Proximal4.165306.65960HepG2BCLAF1
chr1222904712222904764+CDS,intron-Distal4.151743.98716K562IGF2BP1
chr1222898860222898898+CDS,intron-Proximal5.083557.49561HepG2BCLAF1
chr1222893103222893161+intron-Distal4.393083.42734K562PTBP1
chr1222896466222896642+intron-Distal4.778047.58902K562KHSRP
chr1222893098222893223+intron-Distal3.272563.30286HepG2PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for BROX is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for BROX is not available on ENCORE database.

  • 68 RBPs can affect the levels of BROX.  








The Knockdown/knockout RNA-Seq assay for BROX is not available on ENCORE database.





68 RBPs can affect the gene expression of BROX :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
BROXENSG00000162819.7542.19190710.41290-0.389902.269601.55500HepG2ASCC1
BROXENSG00000162819.7382.45400547.90100-0.518602.760501.82500HepG2BCCIP
BROXENSG00000162819.7948.56530688.541100.462102.143501.47690HepG2CNOT7
BROXENSG00000162819.7608.70200825.25080-0.439105.129604.16650HepG2DAZAP1
BROXENSG00000162819.7310.78390465.29040-0.582205.965405.06090HepG2DNAJC2
BROXENSG00000162819.7453.01320339.325300.416802.214001.39600HepG2EIF3D
BROXENSG00000162819.71191.96610959.244700.313303.338602.68750HepG2ETF1
BROXENSG00000162819.7189.13610584.25240-1.6272017.5363016.06370HepG2GPKOW
BROXENSG00000162819.7503.06600711.55790-0.500203.597002.80680HepG2HNRNPK
BROXENSG00000162819.7560.22600751.79550-0.424304.534603.68900HepG2HNRNPL
BROXENSG00000162819.7364.27680523.73590-0.523804.538003.77800HepG2HNRNPU
BROXENSG00000162819.7545.24490761.87440-0.482602.952302.30320HepG2MATR3
BROXENSG00000162819.7786.28610571.611100.459902.257401.31670HepG2PCBP2
BROXENSG00000162819.7366.80090467.13470-0.348801.973801.34250HepG2PPIL4
BROXENSG00000162819.7360.53390480.32500-0.413902.287801.57660HepG2PRPF4
BROXENSG00000162819.7484.16960781.09530-0.690007.793306.86060HepG2PUF60
BROXENSG00000162819.7609.11920829.10800-0.444804.623003.89850HepG2PUM1
BROXENSG00000162819.7611.51030828.53920-0.438203.888403.09610HepG2PUM2
BROXENSG00000162819.7887.88350551.728500.686303.623202.81890HepG2RAVER1
BROXENSG00000162819.7609.36240801.75890-0.395903.338402.78440HepG2RBM22
BROXENSG00000162819.7574.40480766.21760-0.415703.767203.15450HepG2NELFE
BROXENSG00000162819.7575.43060411.076600.485102.670601.89640HepG2RRP9
BROXENSG00000162819.7327.82190466.42410-0.508704.431203.64900HepG2SAFB2
BROXENSG00000162819.7226.66150472.93640-1.061103.034701.60230HepG2SF1
BROXENSG00000162819.7542.98590748.82720-0.463705.585404.64690HepG2SLBP
BROXENSG00000162819.71141.34010905.571000.333704.095003.52000HepG2SRFBP1
BROXENSG00000162819.7868.24230601.177100.530203.420202.18400HepG2STIP1
BROXENSG00000162819.7652.36490877.06720-0.427004.865704.08210HepG2SUCLG1
BROXENSG00000162819.7509.65720672.50730-0.400003.303802.69930HepG2TAF15
BROXENSG00000162819.7373.97070508.99720-0.444703.066302.54440HepG2TIAL1
BROXENSG00000162819.7370.59240513.45070-0.470403.626202.99930HepG2TRIM56
BROXENSG00000162819.7546.04140763.00040-0.482704.400803.26730HepG2TUFM
BROXENSG00000162819.7765.34620493.665700.632503.501602.79980HepG2U2AF1
BROXENSG00000162819.7426.14550558.95730-0.391403.197702.45720HepG2UPF1
BROXENSG00000162819.7405.13570539.65520-0.413603.158602.52630HepG2UTP3
BROXENSG00000162819.7357.05790527.89700-0.564103.418402.61740HepG2XRN2
BROXENSG00000162819.7799.35480614.749600.378704.266703.62690HepG2ZNF622
BROXENSG00000162819.72761.116801737.065000.668509.702108.70800K562AQR
BROXENSG00000162819.71199.04990895.992500.420203.215902.27360K562BOP1
BROXENSG00000162819.71652.523701165.501300.503602.600001.57710K562CNOT7
BROXENSG00000162819.71174.16790952.662500.301502.262701.54690K562CPSF6
BROXENSG00000162819.73162.006002280.210900.471607.620206.02800K562CELF1
BROXENSG00000162819.7886.428701119.26530-0.336503.182502.33110K562EIF3G
BROXENSG00000162819.7885.315801141.52910-0.366702.815201.64610K562EIF4B
BROXENSG00000162819.72208.863901854.629800.252103.210002.20080K562EIF4G2
BROXENSG00000162819.71268.95280969.378500.388403.075102.16880K562FMR1
BROXENSG00000162819.71849.478501220.047100.600102.240901.61410K562G3BP2
BROXENSG00000162819.7550.32250909.53060-0.724806.760705.52160K562GPKOW
BROXENSG00000162819.71321.176901070.055600.304002.479501.46250K562HNRNPA1
BROXENSG00000162819.7957.75790761.730800.330302.367301.80910K562HNRNPC
BROXENSG00000162819.71086.417801445.97720-0.412503.300502.13500K562HNRNPL
BROXENSG00000162819.71079.37450776.698200.474702.863301.91080K562KRR1
BROXENSG00000162819.7661.10020887.81500-0.425403.542302.54480K562METAP2
BROXENSG00000162819.72471.782001976.882600.322202.941701.77180K562MSI2
BROXENSG00000162819.71341.286501169.785000.197302.092301.43340K562NSUN2
BROXENSG00000162819.71454.585901081.988100.426803.169602.27880K562PCBP3
BROXENSG00000162819.7487.77260743.72960-0.608605.706303.58900K562PHF6
BROXENSG00000162819.71093.81320829.909200.398203.803502.85840K562POLR2G
BROXENSG00000162819.71056.677701309.35690-0.309302.215001.48400K562PPIG
BROXENSG00000162819.71532.73450901.323600.7659010.240208.79040K562PRPF8
BROXENSG00000162819.73106.183302023.566700.618109.460107.92970K562PUF60
BROXENSG00000162819.71863.204401406.550200.405503.340902.75290K562PUS1
BROXENSG00000162819.71106.893801608.35520-0.539105.531603.90920K562NELFE
BROXENSG00000162819.71006.21590764.548600.396202.934601.44070K562SDAD1
BROXENSG00000162819.7386.31120590.78210-0.612904.849603.37770K562SRFBP1
BROXENSG00000162819.71465.715601182.598000.309504.149403.02680K562SRPK2
BROXENSG00000162819.71270.502701562.24250-0.298202.523501.84350K562SRSF1
BROXENSG00000162819.7823.699301100.48270-0.417903.640202.40920K562SRSF4
BROXENSG00000162819.71242.16800944.622300.395003.948202.12590K562SRSF9
BROXENSG00000162819.71093.67050832.438000.393702.557701.77070K562SYNCRIP
BROXENSG00000162819.71138.610401525.23800-0.421804.573603.48350K562TIA1
BROXENSG00000162819.71510.419701221.467000.306202.844902.03030K562U2AF2
BROXENSG00000162819.71301.015501061.326000.293702.347601.54010K562WDR3
BROXENSG00000162819.72655.241901956.715200.440305.070803.84640K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for BROX is not available on ENCORE database.





14 RBPs can affect the splicing of BROX :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEBROXENSG00000162819.7chr1+222904698222904858222903368222903519222905969222908538-0.127000.000430.01940excludedK562PRPF8
SEBROXENSG00000162819.7chr1+222895760222895856222892604222892701222897433222897506-0.226000.000010.00076excludedK562AKAP8L
SEBROXENSG00000162819.7chr1+222888486222888611222886722222886758222889025222889142-0.109000.001890.05124excludedK562AKAP8L
SEBROXENSG00000162819.7chr1+2228868802228870092228858942228862842228890252228891420.088000.000040.00078includedK562AQR
SEBROXENSG00000162819.7chr1+222904698222904858222903368222903519222905969222906386-0.146000.000000.00000excludedK562AQR
SEBROXENSG00000162819.7chr1+222898791222898897222897433222897506222900509222900599-0.060000.002660.02777excludedK562AQR
SEBROXENSG00000162819.7chr1+2228884862228886112228867222228867582228890252228891420.140000.001550.05550includedK562FXR1
SEBROXENSG00000162819.7chr1+2228884862228886112228859002228862842228890252228891420.302000.002480.03579includedK562PUS1
SEBROXENSG00000162819.7chr1+222895760222895856222892604222892701222897433222897506-0.334000.000000.00007excludedK562PUS1
SEBROXENSG00000162819.7chr1+222904698222904858222903368222903519222905969222908538-0.120000.000930.04820excludedK562EFTUD2
SEBROXENSG00000162819.7chr1+222895760222895856222892604222892701222897433222897506-0.172000.001060.06730excludedK562HNRNPUL1
SEBROXENSG00000162819.7chr1+222895760222895856222892604222892701222897433222897506-0.167000.002450.06621excludedK562UTP18
SEBROXENSG00000162819.7chr1+2228957602228958562228926042228927012228974332228975060.150000.000170.03410includedK562UPF1
SEBROXENSG00000162819.7chr1+2228869292228870482228859002228862842228890252228891420.289000.000060.00305includedK562RBM15
SEBROXENSG00000162819.7chr1+222895760222895856222892604222892701222897433222897506-0.186000.000200.00766excludedK562RBM15
SEBROXENSG00000162819.7chr1+222895760222895856222892604222892701222897433222897506-0.276000.000000.00003excludedK562AGGF1
SEBROXENSG00000162819.7chr1+2228884862228886112228859002228862842228890252228891420.832000.000010.00702includedHepG2FUBP3
SEBROXENSG00000162819.7chr1+222888486222888611222885900222886284222889025222889142-0.316000.000200.04931excludedHepG2PRPF4
SEBROXENSG00000162819.7chr1+222895760222895856222892604222892701222897433222897506-0.447000.000000.00000excludedK562HNRNPC
A3SSBROXENSG00000162819.7chr1+2229020462229021702229020842229021702229005092229005990.053000.017200.08391longerK562AQR
A3SSBROXENSG00000162819.7chr1+2228974332228975062228974412228975062228926042228927010.662000.000620.07125longerK562HNRNPC
MXEBROXENSG00000162819.7chr1+222886597222886758222886880222887009222885894222886284222889025222889142-0.237000.005070.036362includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for BROX is not avaliable on ENCORE database.