TMEM219

General Information

Gene Name       : TMEM219
Gene ID             : ENSG00000149932.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM219)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM219ENSG00000149932.1613.2322.8418.04ENCSR000AEF
HepG2TMEM219ENSG00000149932.1659.6144.9852.30ENCSR985KAT
K562TMEM219ENSG00000149932.1634.9127.8931.40ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM219 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM219 RNA is bound by 12 proteins.  







eCLIP assay for TMEM219 is not avaliable on ENCORE database.





12 proteins are bound to TMEM219 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr162998290329982992+3'-UTR,intron-Proximal3.3666210.34449HepG2PRPF8
chr162998321129983300+3'-UTR,intron-Distal,intron-Proximal3.912353.06084HepG2HNRNPK
chr162997442929974459+3'-UTR,5'-UTR,intron-Proximal3.920296.27275HepG2DDX3X
chr162998284829982903+3'-UTR,CDS,intron-Proximal3.594226.18341HepG2PRPF8
chr162998277229982869+3'-UTR,CDS4.2822410.43661K562PABPC4
chr162998424329984306+3'-UTR,intron-Proximal3.636865.83621K562AQR
chr162997442629974539+3'-UTR,5'-UTR,CDS,intron-Proximal3.286353.14881K562IGF2BP2
chr162997444529974505+3'-UTR,5'-UTR,CDS4.3958913.70377K562PABPC4
chr162998425829984316+3'-UTR,intron-Proximal4.5625715.91159HepG2U2AF2
chr162998427029984311+3'-UTR,intron-Proximal3.312953.90824K562YBX3
chr162997442329974460+3'-UTR,5'-UTR,intron-Proximal5.139304.32365K562PCBP1
chr162998426829984344+3'-UTR,intron-Proximal4.668678.79791HepG2SUB1
chr162998293229983015+3'-UTR,intron-Distal,intron-Proximal4.366174.22101K562PRPF8
chr162997442629974520+3'-UTR,5'-UTR,CDS,intron-Proximal4.646696.35230K562DDX3X
chr162998289929982942+3'-UTR,intron-Proximal4.346023.11721K562AQR
chr162998289629982955+3'-UTR,intron-Proximal5.468789.60578HepG2AQR
chr162997341829973454+5'-UTR,intron-Distal,intron-Proximal6.227658.97384HepG2DDX3X
chr162997455029974614+CDS4.431784.53890K562PCBP1
chr162997454029974625+CDS3.9918216.49756K562PABPC4
chr162997479829974837+CDS4.020314.17587HepG2DDX3X
chr162997480029974875+CDS4.205847.40140K562YBX3
chr162997455129974626+CDS4.1495620.14506HepG2DDX3X
chr162997481929974914+CDS,intron-Proximal4.1360812.68282HepG2PPIG
chr162997474229974780+CDS3.677585.67297HepG2DDX3X
chr162997952229979572+CDS,intron-Distal3.292203.22545HepG2PPIG
chr162997474029974784+CDS4.1765311.30590HepG2PPIG
chr162997941829979513+CDS,intron-Distal3.048429.39224K562YBX3
chr162997452029974598+CDS3.971195.97131K562DDX3X
chr162997934929979405+CDS,intron-Distal3.291413.67697K562YBX3
chr162997946829979570+CDS,intron-Distal3.549774.44979HepG2GRSF1
chr162997934529979401+CDS,intron-Distal,intron-Proximal4.8605813.19925HepG2PPIG
chr162998261329982678+intron-Distal,intron-Proximal3.520053.62357HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM219 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM219 is not available on ENCORE database.

  • 79 RBPs can affect the levels of TMEM219.  








The Knockdown/knockout RNA-Seq assay for TMEM219 is not available on ENCORE database.





79 RBPs can affect the gene expression of TMEM219 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM219ENSG00000149932.121769.590801414.929100.322603.920703.12980HepG2AUH
TMEM219ENSG00000149932.121210.68880680.050100.832008.447606.98900HepG2BCLAF1
TMEM219ENSG00000149932.12774.95320395.999000.9685012.2803011.14170HepG2BOP1
TMEM219ENSG00000149932.121989.755801575.949500.336302.455201.72300HepG2CIRBP
TMEM219ENSG00000149932.12498.75240363.546200.456102.577301.91030HepG2CPSF6
TMEM219ENSG00000149932.121766.461501270.469400.4754010.359609.06680HepG2DAZAP1
TMEM219ENSG00000149932.122389.885601920.256100.315502.115901.56180HepG2DDX3X
TMEM219ENSG00000149932.12924.85620691.925600.418503.409302.32780HepG2DHX30
TMEM219ENSG00000149932.12906.49540717.374700.337503.093802.35440HepG2DNAJC21
TMEM219ENSG00000149932.121167.28960711.117800.7149016.7196015.24830HepG2DNAJC2
TMEM219ENSG00000149932.122165.402101585.724700.449403.853603.16070HepG2EIF2S1
TMEM219ENSG00000149932.121177.972101706.47580-0.534703.610302.82970HepG2EIF4B
TMEM219ENSG00000149932.121495.506801200.714300.316602.336301.58470HepG2EIF4G2
TMEM219ENSG00000149932.12553.35480412.101300.425102.174501.60350HepG2GPKOW
TMEM219ENSG00000149932.121141.22500805.618100.502304.752803.86160HepG2HNRNPC
TMEM219ENSG00000149932.121030.92730800.285100.365303.841203.00880HepG2HNRNPF
TMEM219ENSG00000149932.12856.60230393.276501.123006.704005.77180HepG2HNRNPLL
TMEM219ENSG00000149932.121083.51340788.047900.459304.625203.71040HepG2IGF2BP1
TMEM219ENSG00000149932.121074.04570817.465200.393705.931804.89490HepG2ILF2
TMEM219ENSG00000149932.121169.82570996.220600.231702.412501.45990HepG2KIF1C
TMEM219ENSG00000149932.121111.183301769.28510-0.671105.356104.45090HepG2MAGOH
TMEM219ENSG00000149932.121350.142801779.05260-0.398002.075301.52370HepG2MATR3
TMEM219ENSG00000149932.121203.514901638.95230-0.445507.455506.53770HepG2PCBP1
TMEM219ENSG00000149932.12924.01640713.790100.372302.180901.51880HepG2PPIL4
TMEM219ENSG00000149932.121452.576401667.67660-0.199201.900201.43050HepG2PTBP1
TMEM219ENSG00000149932.12865.050601202.60450-0.475304.632903.88440HepG2PUF60
TMEM219ENSG00000149932.121722.647001110.041600.6339015.4525014.20350HepG2PUS1
TMEM219ENSG00000149932.121747.116001357.875200.363504.499903.88130HepG2RBM22
TMEM219ENSG00000149932.121131.911701855.97940-0.7134016.8016015.68480HepG2NELFE
TMEM219ENSG00000149932.121231.380401728.56450-0.489308.728607.72580HepG2RECQL
TMEM219ENSG00000149932.121140.06320878.519600.375902.256301.52860HepG2RPS2
TMEM219ENSG00000149932.12920.19910712.678300.368604.214203.44780HepG2SAFB2
TMEM219ENSG00000149932.12447.988401023.23640-1.1916012.5073011.01280HepG2SF3A3
TMEM219ENSG00000149932.121427.197401736.30010-0.282803.385602.73970HepG2SF3B4
TMEM219ENSG00000149932.121607.144701153.150900.478809.792008.59730HepG2SLBP
TMEM219ENSG00000149932.12945.992601812.30770-0.9379029.0146027.84120HepG2SRSF1
TMEM219ENSG00000149932.121041.50380786.269000.405504.640503.77390HepG2SRSF7
TMEM219ENSG00000149932.121018.943701474.39710-0.5331010.215209.27100HepG2SRSF9
TMEM219ENSG00000149932.121030.00070766.078700.427002.308401.68320HepG2SUPV3L1
TMEM219ENSG00000149932.121398.632001628.93490-0.219901.769201.30160HepG2TAF15
TMEM219ENSG00000149932.12621.06490383.340500.696006.097805.08050HepG2TARDBP
TMEM219ENSG00000149932.12939.66720784.588900.260102.401801.86900HepG2TRIM56
TMEM219ENSG00000149932.12651.68960452.507400.526103.451702.60800HepG2UCHL5
TMEM219ENSG00000149932.121385.73290907.454200.6107012.4353011.15060HepG2UPF1
TMEM219ENSG00000149932.121075.64460701.343600.616903.540802.39420HepG2UPF2
TMEM219ENSG00000149932.12667.10450876.11150-0.393204.124503.41570HepG2UTP3
TMEM219ENSG00000149932.121076.94690754.122100.514003.537802.72510HepG2XRN2
TMEM219ENSG00000149932.12900.86470615.006400.550603.124502.41820HepG2ZC3H8
TMEM219ENSG00000149932.121549.95500998.426400.6344012.9811011.85020K562AGGF1
TMEM219ENSG00000149932.121769.378801097.121000.689406.969805.23910K562AKAP8
TMEM219ENSG00000149932.121499.993001038.908200.529802.318701.71960K562AKAP8L
TMEM219ENSG00000149932.121302.578601090.065400.256902.271801.45200K562ATP5C1
TMEM219ENSG00000149932.12553.89650290.339800.931808.712607.11750K562BOP1
TMEM219ENSG00000149932.121474.405701193.173300.305202.787401.60730K562CCDC124
TMEM219ENSG00000149932.12534.13200308.688600.790905.598804.49090K562CPSF6
TMEM219ENSG00000149932.12600.89120464.867800.370202.659101.62330K562CSTF2
TMEM219ENSG00000149932.121027.01150675.316700.604706.691004.98590K562DDX3X
TMEM219ENSG00000149932.12860.12530684.688700.329002.863401.52490K562DDX6
TMEM219ENSG00000149932.12953.00080642.817400.568007.425406.32950K562EIF2S2
TMEM219ENSG00000149932.12796.41130615.880500.370802.906901.57960K562EWSR1
TMEM219ENSG00000149932.12709.64930410.685600.789008.590707.00360K562FIP1L1
TMEM219ENSG00000149932.12526.73040314.133500.745606.133604.84780K562FMR1
TMEM219ENSG00000149932.12465.03830266.278200.804303.678802.61080K562FTO
TMEM219ENSG00000149932.12531.74550733.74450-0.464504.453803.71070K562FXR1
TMEM219ENSG00000149932.12190.87180390.72900-1.033606.256005.09590K562G3BP2
TMEM219ENSG00000149932.12475.55350294.700900.690305.335304.23900K562GPKOW
TMEM219ENSG00000149932.121569.70730856.535300.8738014.6795012.90270K562GRSF1
TMEM219ENSG00000149932.12504.18010337.838400.577503.643502.56240K562HNRNPM
TMEM219ENSG00000149932.12807.81940556.741400.536904.538403.52450K562HSPD1
TMEM219ENSG00000149932.12843.31270614.920700.455602.745801.72460K562IGF2BP2
TMEM219ENSG00000149932.121398.259501102.540200.342703.296302.38830K562KIF1C
TMEM219ENSG00000149932.121442.076001055.403200.450304.483303.02020K562MAK16
TMEM219ENSG00000149932.12444.64560287.669700.628104.495303.36180K562METAP2
TMEM219ENSG00000149932.12758.46760560.741400.435704.575203.55690K562MTPAP
TMEM219ENSG00000149932.12901.42130704.519200.355502.923501.65930K562NCBP2
TMEM219ENSG00000149932.12854.71450623.015300.456106.012004.97120K562NSUN2
TMEM219ENSG00000149932.12935.89810625.843500.580402.394601.48760K562PABPN1
TMEM219ENSG00000149932.12761.59270466.272200.707707.283505.82740K562PPIG
TMEM219ENSG00000149932.121223.07800744.323400.716403.163601.56370K562PPP1R8
TMEM219ENSG00000149932.121677.104101030.309700.702809.267208.32360K562PUS1
TMEM219ENSG00000149932.121356.596901003.883400.434305.306604.50920K562RBM15
TMEM219ENSG00000149932.12799.39220581.252000.459603.592302.36550K562SRSF5
TMEM219ENSG00000149932.12819.25750622.796000.395502.489801.81610K562TARDBP
TMEM219ENSG00000149932.12793.37270600.767200.401103.199102.30970K562TIA1
TMEM219ENSG00000149932.12276.21680390.88750-0.501002.904902.08170K562U2AF2
TMEM219ENSG00000149932.12710.91100482.264900.559704.110602.84420K562UCHL5
TMEM219ENSG00000149932.12940.43330660.597800.509507.003405.91940K562UPF1
TMEM219ENSG00000149932.12807.38670565.250200.514304.893903.71270K562WDR3
TMEM219ENSG00000149932.12673.16340491.183700.454602.764301.55910K562XRN2
TMEM219ENSG00000149932.121459.709501122.923300.378303.428002.45110K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM219 is not available on ENCORE database.





12 RBPs can affect the splicing of TMEM219 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETMEM219ENSG00000149932.12chr16+2998336229983461299827282998289929984270299843690.099000.001120.02308includedK562SRSF1
SETMEM219ENSG00000149932.12chr16+299833622998346129982728299828992998427029984369-0.061000.003110.07377excludedK562AKAP8L
SETMEM219ENSG00000149932.12chr16+299833622998346129982728299828992998427029984369-0.124000.000020.02641excludedK562UTP3
SETMEM219ENSG00000149932.12chr16+2998336229983461299827282998289929984270299843690.152000.000000.00007includedK562FXR1
SETMEM219ENSG00000149932.12chr16+2998336229983461299827282998289929984270299843690.059000.000920.09824includedK562DROSHA
SETMEM219ENSG00000149932.12chr16+2998336229983461299827282998289929984270299843690.204000.000000.00000includedHepG2HNRNPL
SETMEM219ENSG00000149932.12chr16+2998336229983461299827282998289929984270299843690.288000.000000.00000includedK562HNRNPL
SETMEM219ENSG00000149932.12chr16+299833622998346129982728299828992998427029984369-0.143000.000220.03977excludedK562SRSF7
SETMEM219ENSG00000149932.12chr16+299833622998346129982728299828992998427029984369-0.065000.000690.02078excludedK562AGGF1
SETMEM219ENSG00000149932.12chr16+2998336229983461299827282998289929984270299843690.279000.000000.00000includedK562HNRNPC
A5SSTMEM219ENSG00000149932.12chr16+2997340729973553299734072997345329974430299746290.056000.005320.07644longerK562AQR
RITMEM219ENSG00000149932.12chr16+299739972997462929973997299740182997443029974629-0.069000.001350.01496excludedHepG2U2AF1
MXETMEM219ENSG00000149932.12chr16+29974430299746292997472029974910299734072997345329979345299795750.147000.000020.001411includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM219 is not avaliable on ENCORE database.