TIMMDC1

General Information

Gene Name       : TIMMDC1
Gene ID             : ENSG00000113845.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TIMMDC1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TIMMDC1ENSG00000113845.940.5838.5839.58ENCSR000AEF
HepG2TIMMDC1ENSG00000113845.940.1655.5547.85ENCSR985KAT
K562TIMMDC1ENSG00000113845.949.1752.9351.05ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TIMMDC1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TIMMDC1 RNA is bound by 11 proteins.  







eCLIP assay for TIMMDC1 is not avaliable on ENCORE database.





11 proteins are bound to TIMMDC1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr3119232489119232567+3'-UTR,CDS,intron-Distal,intron-Proximal3.4905410.57780K562LIN28B
chr3119242653119242696+3'-UTR3.896403.02850K562YBX3
chr3119232496119232569+3'-UTR,CDS,intron-Distal,intron-Proximal5.020927.95701HepG2PPIG
chr3119236070119236149+3'-UTR,CDS3.952013.56019HepG2GRWD1
chr3119232495119232554+3'-UTR,CDS,intron-Distal3.561154.08943HepG2LIN28B
chr3119236032119236093+3'-UTR,CDS,intron-Proximal5.040377.27507HepG2U2AF2
chr3119219569119219628+5'-UTR,CDS,intron-Distal3.482355.37252K562YBX3
chr3119217418119217600+5'-UTR,CDS3.602169.02088K562DDX3X
chr3119217765119217847+5'-UTR,CDS,intron-Proximal4.466294.92499HepG2AQR
chr3119217430119217489+5'-UTR4.716464.66990HepG2DDX3X
chr3119217629119217698+CDS4.409464.34093HepG2RBM15
chr3119217635119217742+CDS4.131553.57015HepG2SRSF7
chr3119226167119226235+intron-Distal4.184903.27946HepG2HNRNPM
chr3119226162119226235+intron-Distal3.433733.59351HepG2MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TIMMDC1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TIMMDC1 is not available on ENCORE database.

  • 75 RBPs can affect the levels of TIMMDC1.  








The Knockdown/knockout RNA-Seq assay for TIMMDC1 is not available on ENCORE database.





75 RBPs can affect the gene expression of TIMMDC1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TIMMDC1ENSG00000113845.5791.62790626.092400.338303.276702.62410HepG2ACO1
TIMMDC1ENSG00000113845.51593.838601126.348900.500803.746203.14050HepG2AKAP1
TIMMDC1ENSG00000113845.5411.65780552.35810-0.424202.469901.30780HepG2BUD13
TIMMDC1ENSG00000113845.5691.18770885.43190-0.357302.124901.44190HepG2CIRBP
TIMMDC1ENSG00000113845.5503.56380625.86690-0.313702.574101.92820HepG2CKAP4
TIMMDC1ENSG00000113845.5758.44670427.307500.827705.382104.31250HepG2CNOT7
TIMMDC1ENSG00000113845.51313.83580975.725000.429105.689004.83020HepG2CELF1
TIMMDC1ENSG00000113845.51496.794401078.979400.472103.840203.11440HepG2DDX3X
TIMMDC1ENSG00000113845.5510.03580688.34770-0.432502.251201.54650HepG2DDX55
TIMMDC1ENSG00000113845.5417.82140705.81700-0.756404.063902.89190HepG2DDX59
TIMMDC1ENSG00000113845.5606.96520926.81300-0.610704.573103.79570HepG2DDX6
TIMMDC1ENSG00000113845.5438.44230551.05490-0.329802.235601.59760HepG2DNAJC21
TIMMDC1ENSG00000113845.5453.20480546.18950-0.269201.931401.36890HepG2DNAJC2
TIMMDC1ENSG00000113845.5371.85200525.01110-0.497602.583401.51870HepG2AGO1
TIMMDC1ENSG00000113845.5285.14130891.02000-1.6438027.2878025.56410HepG2EIF2S1
TIMMDC1ENSG00000113845.5853.356301035.04520-0.278502.559801.74910HepG2EIF4G1
TIMMDC1ENSG00000113845.5331.32660625.09420-0.9158010.518709.03330HepG2FUBP3
TIMMDC1ENSG00000113845.5311.37680433.77980-0.478302.549301.69400HepG2GEMIN5
TIMMDC1ENSG00000113845.5470.60390597.68480-0.344902.784001.80420HepG2HDGF
TIMMDC1ENSG00000113845.5747.13870919.31750-0.299202.596801.90130HepG2HNRNPF
TIMMDC1ENSG00000113845.5622.95560933.12230-0.582905.213604.27820HepG2HNRNPK
TIMMDC1ENSG00000113845.5809.61360955.69290-0.239302.279001.65920HepG2HNRNPL
TIMMDC1ENSG00000113845.5496.67170614.72780-0.307702.277901.72260HepG2HNRNPU
TIMMDC1ENSG00000113845.5814.834701040.33130-0.352503.242402.41910HepG2NOL12
TIMMDC1ENSG00000113845.5416.55430632.06710-0.601602.467801.44020HepG2NONO
TIMMDC1ENSG00000113845.5578.81990911.02680-0.654405.727704.70140HepG2PABPC4
TIMMDC1ENSG00000113845.5749.66060881.06280-0.233001.822501.31280HepG2PCBP1
TIMMDC1ENSG00000113845.5349.53530531.02200-0.603303.829602.89910HepG2PRPF8
TIMMDC1ENSG00000113845.5752.62920896.50860-0.252402.111601.62150HepG2PTBP1
TIMMDC1ENSG00000113845.5677.79940993.08660-0.551105.629004.81790HepG2PUF60
TIMMDC1ENSG00000113845.5699.10610970.95320-0.473905.011604.20830HepG2QKI
TIMMDC1ENSG00000113845.51415.504801081.963700.387604.635704.00990HepG2RBM22
TIMMDC1ENSG00000113845.5633.20180881.19780-0.476804.353403.52380HepG2RBM25
TIMMDC1ENSG00000113845.5791.42390997.73280-0.334203.144502.57490HepG2NELFE
TIMMDC1ENSG00000113845.5700.31890929.24390-0.408004.425203.66900HepG2RECQL
TIMMDC1ENSG00000113845.5613.94020428.674700.518102.748001.95110HepG2RPS3A
TIMMDC1ENSG00000113845.5493.494201081.20590-1.131503.765302.13440HepG2SF1
TIMMDC1ENSG00000113845.5480.60580718.22120-0.579603.129202.41260HepG2SF3A3
TIMMDC1ENSG00000113845.5736.51390933.39150-0.341803.285202.64720HepG2SF3B4
TIMMDC1ENSG00000113845.5776.34640952.21340-0.294602.966102.24200HepG2SLBP
TIMMDC1ENSG00000113845.5776.20570638.409900.281902.583601.95850HepG2SMN1
TIMMDC1ENSG00000113845.5454.53010966.06570-1.087703.848502.24090HepG2SNRNP200
TIMMDC1ENSG00000113845.5561.35960974.25440-0.7954014.3714013.47340HepG2SRSF1
TIMMDC1ENSG00000113845.5752.35770903.18750-0.263602.083101.46960HepG2SRSF7
TIMMDC1ENSG00000113845.5629.24120792.60430-0.333003.198202.61410HepG2SRSF9
TIMMDC1ENSG00000113845.5688.98790875.68620-0.345903.062202.47640HepG2TAF15
TIMMDC1ENSG00000113845.5556.51410804.64870-0.531905.285904.14220HepG2TIA1
TIMMDC1ENSG00000113845.5543.123801124.04180-1.049303.302702.22230HepG2U2AF2
TIMMDC1ENSG00000113845.5360.74070544.29260-0.593406.451405.49600HepG2ZC3H8
TIMMDC1ENSG00000113845.5626.38710946.39650-0.595408.579707.65350K562AGGF1
TIMMDC1ENSG00000113845.5837.902601528.55310-0.8673013.0410011.90150K562AQR
TIMMDC1ENSG00000113845.5728.42000978.82240-0.426304.799202.98860K562BCCIP
TIMMDC1ENSG00000113845.5652.65080895.68600-0.456703.139001.60620K562BUD13
TIMMDC1ENSG00000113845.5314.10320452.65690-0.527203.345502.16310K562CCAR1
TIMMDC1ENSG00000113845.5459.83060758.38340-0.721806.833405.34630K562EFTUD2
TIMMDC1ENSG00000113845.5348.17940657.25450-0.9166014.3851011.66880K562EIF2S1
TIMMDC1ENSG00000113845.5574.24080812.04700-0.499903.095801.99860K562EIF3D
TIMMDC1ENSG00000113845.5786.52410650.139100.274602.005201.47410K562FXR1
TIMMDC1ENSG00000113845.5554.13990760.32510-0.456402.898801.43850K562GEMIN5
TIMMDC1ENSG00000113845.5584.63810849.13650-0.538504.993704.21500K562HNRNPC
TIMMDC1ENSG00000113845.5548.56560758.26410-0.467003.717302.37530K562HNRNPF
TIMMDC1ENSG00000113845.5972.725701196.71720-0.299002.756001.86340K562HNRNPU
TIMMDC1ENSG00000113845.5408.14390684.57120-0.746103.278702.25370K562KRR1
TIMMDC1ENSG00000113845.5622.57100822.23220-0.401302.949901.50870K562LARP7
TIMMDC1ENSG00000113845.5935.319001170.80620-0.324002.691901.79850K562MBNL1
TIMMDC1ENSG00000113845.5530.87270782.71030-0.560102.276501.48350K562METAP2
TIMMDC1ENSG00000113845.5824.71950970.75660-0.235202.013401.31800K562MTPAP
TIMMDC1ENSG00000113845.5892.987701078.63260-0.272503.020802.24470K562NSUN2
TIMMDC1ENSG00000113845.5565.41800794.39090-0.490504.040902.85350K562PCBP2
TIMMDC1ENSG00000113845.5551.18140737.99310-0.421102.631401.89950K562PRPF8
TIMMDC1ENSG00000113845.5578.01550761.33540-0.397403.151302.17720K562PSIP1
TIMMDC1ENSG00000113845.5680.97730976.74760-0.520404.474603.80770K562PUS1
TIMMDC1ENSG00000113845.5722.75280951.57070-0.396803.554802.89650K562RBM15
TIMMDC1ENSG00000113845.5658.42950831.73530-0.337102.250801.49720K562RBM22
TIMMDC1ENSG00000113845.5389.60300547.19540-0.490103.347301.86620K562RBM25
TIMMDC1ENSG00000113845.5511.41350694.59870-0.441703.413802.31510K562RCC2
TIMMDC1ENSG00000113845.5851.636601064.28330-0.321603.125202.25910K562SF3A3
TIMMDC1ENSG00000113845.5348.67820599.80350-0.782607.112305.70130K562SF3B4
TIMMDC1ENSG00000113845.5461.95520658.46320-0.511303.732502.49140K562SRFBP1
TIMMDC1ENSG00000113845.5898.069601090.37660-0.279902.955601.99320K562SRPK2
TIMMDC1ENSG00000113845.5425.88410850.41300-0.9977015.3648013.69560K562SRSF1
TIMMDC1ENSG00000113845.5525.19090732.27990-0.479603.172402.16480K562TIAL1
TIMMDC1ENSG00000113845.5535.04610777.92900-0.540004.731003.41430K562TRIM56
TIMMDC1ENSG00000113845.5369.62120559.22770-0.597403.859502.52440K562U2AF1
TIMMDC1ENSG00000113845.5428.51870577.38760-0.430202.868302.05020K562U2AF2
TIMMDC1ENSG00000113845.5810.127201059.12120-0.386602.640101.46970K562UTP3
TIMMDC1ENSG00000113845.5715.51210978.62760-0.451803.815002.78300K562WDR3
TIMMDC1ENSG00000113845.51268.981401722.05380-0.440504.623403.46570K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TIMMDC1 is not available on ENCORE database.





13 RBPs can affect the splicing of TIMMDC1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETIMMDC1ENSG00000113845.5chr3+119222378119222467119219541119219707119222800119222868-0.185000.000000.00005excludedK562SF3B4
SETIMMDC1ENSG00000113845.5chr3+119222378119222467119219541119219707119222800119222868-0.234000.000020.00068excludedHepG2U2AF1
SETIMMDC1ENSG00000113845.5chr3+1192228001192228681192174271192177741192324871192325660.054000.000120.03986includedK562PUM1
SETIMMDC1ENSG00000113845.5chr3+119219541119219707119217378119217774119232487119232566-0.188000.000150.00559excludedHepG2HNRNPK
SETIMMDC1ENSG00000113845.5chr3+1192195411192197071192173781192177741192324871192325660.089000.000960.07204includedHepG2TBRG4
SETIMMDC1ENSG00000113845.5chr3+119222378119222467119219541119219707119222800119222868-0.315000.000000.00002excludedHepG2U2AF2
SETIMMDC1ENSG00000113845.5chr3+1192228001192228681192192201192197071192324871192325660.063000.000440.03228includedHepG2AKAP1
SETIMMDC1ENSG00000113845.5chr3+119232487119232566119219220119219707119236051119236162-0.071000.012950.09961excludedK562AQR
SETIMMDC1ENSG00000113845.5chr3+119222378119222467119219541119219707119222800119222868-0.139000.000030.00110excludedK562U2AF1
SETIMMDC1ENSG00000113845.5chr3+119219541119219707119217378119217774119232487119232566-0.146000.000510.04539excludedHepG2DDX6
SETIMMDC1ENSG00000113845.5chr3+119217566119217774119217413119217435119219541119219707-0.083000.000160.03458excludedK562EIF4G2
SETIMMDC1ENSG00000113845.5chr3+119222378119222467119219541119219707119222800119222868-0.101000.000030.00257excludedHepG2SF3B4
SETIMMDC1ENSG00000113845.5chr3+119222378119222467119219541119219707119222800119222868-0.139000.000050.00165excludedK562U2AF2
SETIMMDC1ENSG00000113845.5chr3+119222378119222467119219541119219707119222800119222868-0.058000.001100.04827excludedK562HNRNPK
A5SSTIMMDC1ENSG00000113845.5chr3+119217378119217774119217378119217435119219541119219707-0.146000.000030.00913shorterK562SUPV3L1
A5SSTIMMDC1ENSG00000113845.5chr3+119217378119217774119217378119217435119219541119219707-0.083000.001590.08502shorterHepG2SRSF1
A5SSTIMMDC1ENSG00000113845.5chr3+119217378119217774119217378119217435119219541119219707-0.088000.000140.01498shorterK562HNRNPC
A5SSTIMMDC1ENSG00000113845.5chr3+119217378119217774119217378119217435119219541119219707-0.067000.000190.07432shorterK562EIF4G2
A5SSTIMMDC1ENSG00000113845.5chr3+119217378119217774119217378119217435119219541119219707-0.183000.000080.00659shorterK562SRSF1
MXETIMMDC1ENSG00000113845.5chr3+1192195411192197071192228051192228681192173931192174351192324871192325660.162000.002070.034641includedK562U2AF1
MXETIMMDC1ENSG00000113845.5chr3+1192195411192197071192228051192228681192173931192174351192324871192325660.173000.005070.065881includedK562SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TIMMDC1 is not avaliable on ENCORE database.