TARS2

General Information

Gene Name       : TARS2
Gene ID             : ENSG00000143374.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TARS2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TARS2ENSG00000143374.1623.1931.4527.32ENCSR000AEF
HepG2TARS2ENSG00000143374.1622.9820.3221.65ENCSR985KAT
K562TARS2ENSG00000143374.1645.1243.2144.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TARS2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TARS2 RNA is bound by 5 proteins.  







eCLIP assay for TARS2 is not avaliable on ENCORE database.





5 proteins are bound to TARS2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1150479973150479987+3'-UTR4.290183.06853K562LIN28B
chr1150480004150480046+3'-UTR6.2149720.10050K562LIN28B
chr1150479987150480004+3'-UTR6.0711817.63566K562LIN28B
chr1150476910150476968+3'-UTR,CDS,intron-Proximal4.419445.97994K562AQR
chr1150477362150477423+3'-UTR,CDS,intron-Proximal3.292564.83230K562AQR
chr1150477364150477440+3'-UTR,CDS,intron-Proximal3.651205.37652K562BUD13
chr1150479514150479595+3'-UTR,CDS4.230439.91453K562PUM2
chr1150464939150464997+5'-UTR,CDS,intron-Distal,intron-Proximal3.815224.83899HepG2PRPF8
chr1150461396150461479+CDS,intron-Proximal3.680537.44037K562BUD13
chr1150460529150460576+CDS,intron-Proximal6.5010718.62356K562AQR
chr1150461397150461449+CDS,intron-Proximal4.2930613.09382K562AQR
chr1150463974150464029+CDS,intron-Distal,intron-Proximal3.091954.21588K562PRPF8
chr1150463962150463998+CDS,intron-Distal,intron-Proximal4.7152116.50149HepG2PRPF8
chr1150463998150464025+intron-Distal,intron-Proximal4.9068014.13178HepG2PRPF8
chr1150477459150477536+intron-Proximal5.540079.41643K562AQR
chr1150460576150460600+intron-Proximal4.784595.26064K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TARS2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TARS2 is not available on ENCORE database.

  • 82 RBPs can affect the levels of TARS2.  








The Knockdown/knockout RNA-Seq assay for TARS2 is not available on ENCORE database.





82 RBPs can affect the gene expression of TARS2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TARS2ENSG00000143374.10377.36960538.99140-0.514303.127702.29270HepG2ASCC1
TARS2ENSG00000143374.10383.02120513.70960-0.423502.113901.32410HepG2BCLAF1
TARS2ENSG00000143374.10418.31600546.40650-0.385403.274102.56120HepG2CKAP4
TARS2ENSG00000143374.10828.33840364.699201.1834010.137408.70690HepG2CNOT7
TARS2ENSG00000143374.10394.60040551.61880-0.483303.041902.32520HepG2CPSF6
TARS2ENSG00000143374.10337.68720539.12230-0.674903.130301.90260HepG2DDX1
TARS2ENSG00000143374.10397.48770626.40610-0.656203.033902.01130HepG2DDX59
TARS2ENSG00000143374.10403.14170536.04970-0.411101.949201.42270HepG2DDX6
TARS2ENSG00000143374.10390.90570522.94710-0.419803.153802.43780HepG2DKC1
TARS2ENSG00000143374.10374.35940515.29940-0.461002.542901.97440HepG2EIF2S1
TARS2ENSG00000143374.10366.06840554.46370-0.599003.107402.38170HepG2EIF4B
TARS2ENSG00000143374.10464.69280623.29260-0.423602.779701.68390HepG2ESF1
TARS2ENSG00000143374.10652.464201043.21210-0.6771011.6428010.54880HepG2ETF1
TARS2ENSG00000143374.10757.24090574.585500.398102.346501.70740HepG2FXR1
TARS2ENSG00000143374.10388.12880532.99830-0.457602.512901.87700HepG2G3BP1
TARS2ENSG00000143374.10581.06960811.89380-0.482604.966703.77400HepG2HNRNPA2B1
TARS2ENSG00000143374.10360.74840593.66140-0.718603.616002.83110HepG2HNRNPC
TARS2ENSG00000143374.10632.05530786.88190-0.316102.572601.88030HepG2HNRNPF
TARS2ENSG00000143374.10783.10890539.741700.536804.212403.36610HepG2HNRNPK
TARS2ENSG00000143374.10610.50300804.61920-0.398303.524502.77070HepG2HNRNPL
TARS2ENSG00000143374.10325.25280596.72110-0.875508.053307.04200HepG2HNRNPLL
TARS2ENSG00000143374.10661.82980881.04620-0.412802.295601.54510HepG2LARP4
TARS2ENSG00000143374.10651.23320875.93510-0.427603.824402.92700HepG2NOL12
TARS2ENSG00000143374.10326.10360529.12170-0.698305.106104.10260HepG2NSUN2
TARS2ENSG00000143374.10447.45760558.22380-0.319102.303701.73950HepG2PCBP1
TARS2ENSG00000143374.10492.10540604.80690-0.297502.115301.43120HepG2PRPF4
TARS2ENSG00000143374.10300.25580448.37340-0.578503.444702.55330HepG2PRPF8
TARS2ENSG00000143374.10529.23870836.19720-0.659906.742605.86660HepG2PUF60
TARS2ENSG00000143374.10713.61320887.02980-0.313802.118501.52770HepG2PUM2
TARS2ENSG00000143374.10220.88920467.38430-1.081306.264705.22700HepG2RAVER1
TARS2ENSG00000143374.10653.38760871.92550-0.416303.730203.15210HepG2RBM22
TARS2ENSG00000143374.10371.34200558.31110-0.588304.904504.02980HepG2RBM25
TARS2ENSG00000143374.10453.49990588.72910-0.376502.907502.27690HepG2RECQL
TARS2ENSG00000143374.10597.30670847.62180-0.504904.157703.34750HepG2RPLP0
TARS2ENSG00000143374.10224.66740459.40240-1.032007.094505.63580HepG2RPS10
TARS2ENSG00000143374.10343.97310569.86250-0.728306.096404.93300HepG2RPS2
TARS2ENSG00000143374.10282.69430443.52790-0.649803.855802.94560HepG2RRP9
TARS2ENSG00000143374.10490.78600801.88010-0.7083010.627609.39740HepG2SLBP
TARS2ENSG00000143374.10262.19030657.17760-1.3257011.543509.96380HepG2SNRNP70
TARS2ENSG00000143374.10672.13470984.79600-0.551108.203207.46640HepG2SRFBP1
TARS2ENSG00000143374.10807.66840617.268800.387803.617203.09410HepG2SRSF1
TARS2ENSG00000143374.10602.03830825.67980-0.455704.668403.89110HepG2SRSF5
TARS2ENSG00000143374.10519.49510773.07560-0.573507.130906.09700HepG2SRSF7
TARS2ENSG00000143374.10502.10470855.01540-0.7680013.2248012.26930HepG2SSB
TARS2ENSG00000143374.10343.31600490.56110-0.514903.483802.43850HepG2SUPT6H
TARS2ENSG00000143374.10277.89520578.67050-1.058209.721608.58170HepG2SUPV3L1
TARS2ENSG00000143374.10424.38210581.67040-0.454802.919502.17730HepG2TARDBP
TARS2ENSG00000143374.10277.80460387.85140-0.481402.515501.55930HepG2TFIP11
TARS2ENSG00000143374.10421.66020572.87620-0.442101.909401.47650HepG2TIAL1
TARS2ENSG00000143374.10450.70530590.48350-0.389703.288102.53740HepG2UPF1
TARS2ENSG00000143374.10485.82450596.89360-0.297002.226201.61450HepG2ZC3H8
TARS2ENSG00000143374.10514.37470649.41950-0.336303.047502.48070HepG2ZNF622
TARS2ENSG00000143374.101905.333401470.649500.373503.373102.65020K562AKAP8L
TARS2ENSG00000143374.10821.368101780.45280-1.1161021.1298019.68280K562AQR
TARS2ENSG00000143374.10641.43400868.84800-0.437803.178902.03340K562CCAR1
TARS2ENSG00000143374.102403.639902846.66260-0.244102.203701.33390K562CELF1
TARS2ENSG00000143374.101350.114401746.48030-0.371405.312704.45110K562DDX47
TARS2ENSG00000143374.101880.036801582.656500.248302.390801.58490K562DKC1
TARS2ENSG00000143374.10714.73570992.20720-0.473203.917002.81510K562EFTUD2
TARS2ENSG00000143374.101072.482801436.29370-0.421405.588304.61900K562EIF2S2
TARS2ENSG00000143374.10590.40340883.80250-0.582003.218402.12570K562EIF3A
TARS2ENSG00000143374.10727.679901062.34480-0.545904.019502.74430K562EIF3D
TARS2ENSG00000143374.101901.259002315.20690-0.284203.339102.31060K562EIF4G2
TARS2ENSG00000143374.10761.425401045.86340-0.457903.353402.09230K562FKBP4
TARS2ENSG00000143374.10615.63230890.22020-0.532104.457003.36930K562FMR1
TARS2ENSG00000143374.10578.78850754.52800-0.382502.255801.43490K562FTO
TARS2ENSG00000143374.10398.49720752.04110-0.916207.923206.60050K562G3BP2
TARS2ENSG00000143374.101157.506701432.06660-0.307103.046001.84900K562GLRX3
TARS2ENSG00000143374.101395.191401914.01240-0.456105.205904.16440K562GRSF1
TARS2ENSG00000143374.10710.431001204.84900-0.7621010.791809.67690K562HNRNPC
TARS2ENSG00000143374.101292.840801711.21290-0.404505.230403.98830K562HNRNPU
TARS2ENSG00000143374.10505.17350713.28070-0.497702.758301.82700K562KRR1
TARS2ENSG00000143374.101140.046801505.64490-0.401305.804104.66170K562MTPAP
TARS2ENSG00000143374.101363.950701672.83010-0.294504.559003.63030K562NSUN2
TARS2ENSG00000143374.10739.272601073.65190-0.538304.029902.84360K562PCBP2
TARS2ENSG00000143374.101224.092301562.45510-0.352102.393701.62150K562PCBP3
TARS2ENSG00000143374.10642.70900965.53210-0.587205.205304.17710K562PRPF8
TARS2ENSG00000143374.101889.312102526.07290-0.419004.682103.62380K562PUF60
TARS2ENSG00000143374.102099.648802686.82190-0.355804.236002.89390K562PUM1
TARS2ENSG00000143374.102215.565802632.60760-0.248802.671401.72800K562PUM2
TARS2ENSG00000143374.10603.00440983.49690-0.705806.119604.89780K562RPS19
TARS2ENSG00000143374.101411.194301650.77030-0.226202.104601.38690K562SF3A3
TARS2ENSG00000143374.10497.42570794.43340-0.675405.313903.93690K562SF3B1
TARS2ENSG00000143374.10698.97860957.10100-0.453403.198801.83230K562SLBP
TARS2ENSG00000143374.10437.98260728.67180-0.734406.236104.45220K562U2AF1
TARS2ENSG00000143374.10332.77360752.65770-1.1775020.6084018.38130K562U2AF2
TARS2ENSG00000143374.101401.140701773.74330-0.340204.636603.73150K562UPF1
TARS2ENSG00000143374.101172.828801517.72620-0.371903.588502.59350K562WDR3
TARS2ENSG00000143374.101245.890901578.32720-0.341204.382503.33490K562WDR43
TARS2ENSG00000143374.101603.474602109.36380-0.395604.287502.66990K562WRN
TARS2ENSG00000143374.101291.777602005.81050-0.634809.073307.38730K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TARS2 is not available on ENCORE database.





25 RBPs can affect the splicing of TARS2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETARS2ENSG00000143374.10chr1+1504771071504772091504768101504769111504773811504774540.193000.000750.01636includedK562SRSF1
SETARS2ENSG00000143374.10chr1+150468957150469104150464886150464965150470005150470223-0.228000.000500.01184excludedK562SRSF1
SETARS2ENSG00000143374.10chr1+150464073150464138150463869150463987150464886150464965-0.329000.000450.01045excludedHepG2U2AF1
SETARS2ENSG00000143374.10chr1+150468957150469104150464886150464965150470005150470223-0.456000.000830.01751excludedHepG2U2AF1
SETARS2ENSG00000143374.10chr1+150469285150469384150464660150464965150470005150470063-0.161000.001200.03644excludedK562AKAP8L
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.420000.000000.00000excludedK562PCBP1
SETARS2ENSG00000143374.10chr1+150464073150464138150463869150463987150464886150464965-0.534000.000310.00525excludedHepG2U2AF2
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.206000.000640.00834excludedK562AQR
SETARS2ENSG00000143374.10chr1+150470977150471140150470005150470223150471372150471510-0.063000.001000.01222excludedK562AQR
SETARS2ENSG00000143374.10chr1+150468957150469104150464660150464965150469285150469384-0.095000.000370.01778excludedK562FXR1
SETARS2ENSG00000143374.10chr1+150469285150469384150464660150464965150470005150470063-0.139000.005060.06273excludedK562PUS1
SETARS2ENSG00000143374.10chr1+1504689571504691041504646601504649651504692851504693840.109000.000060.01944includedK562SBDS
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.286000.000000.00204excludedK562SBDS
SETARS2ENSG00000143374.10chr1+150469285150469384150464660150464965150470005150470063-0.352000.003850.08657excludedHepG2SF3A3
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.221000.000020.00341excludedK562HNRNPUL1
SETARS2ENSG00000143374.10chr1+150469285150469384150464660150464965150470005150470063-0.344000.001270.07981excludedHepG2TIAL1
SETARS2ENSG00000143374.10chr1+150468957150469104150464886150464965150470005150470223-0.429000.000190.02489excludedHepG2SUPV3L1
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.491000.000010.00104excludedHepG2PCBP1
SETARS2ENSG00000143374.10chr1+150468957150469104150464886150464965150470005150470223-0.358000.000260.08244excludedHepG2BCCIP
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.366000.000430.02375excludedHepG2SF3B4
SETARS2ENSG00000143374.10chr1+150469285150469384150464660150464965150470005150470063-0.145000.003420.08402excludedK562UTP18
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.454000.000040.00885excludedHepG2TAF15
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.512000.000130.00354excludedK562U2AF2
SETARS2ENSG00000143374.10chr1+150469285150469384150464660150464965150470005150470223-0.220000.000330.01586excludedK562TARDBP
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.213000.001370.03474excludedK562RBM15
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.534000.000240.01328excludedK562SF3B1
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.235000.000130.02596excludedK562ZC3H8
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.367000.001360.04903excludedHepG2HNRNPC
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.395000.000550.03930excludedHepG2SRSF9
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.243000.000000.00309excludedK562NPM1
SETARS2ENSG00000143374.10chr1+150477107150477209150476810150476911150477381150477454-0.455000.000000.00001excludedK562HNRNPC
MXETARS2ENSG00000143374.10chr1+150469285150469384150470005150470223150468957150469104150470977150471140-0.137000.002770.058512includedK562TARDBP
MXETARS2ENSG00000143374.10chr1+150469285150469384150470005150470223150464886150464965150470977150471140-0.110000.000020.002262includedK562SBDS
MXETARS2ENSG00000143374.10chr1+150468957150469104150469285150469384150464886150464965150470005150470223-0.389000.000110.006412includedHepG2SUPV3L1
MXETARS2ENSG00000143374.10chr1+1504648861504649651504689571504691041504640731504641381504692851504693840.262000.002840.063811includedHepG2TIAL1
MXETARS2ENSG00000143374.10chr1+150469285150469384150470005150470223150468957150469104150470977150471140-0.232000.001390.039972includedHepG2TIAL1
MXETARS2ENSG00000143374.10chr1+150469285150469384150470005150470223150468957150469104150470977150471140-0.174000.006020.086102includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TARS2 is not avaliable on ENCORE database.