SFXN4

General Information

Gene Name       : SFXN4
Gene ID             : ENSG00000183605.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SFXN4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SFXN4ENSG00000183605.1651.2031.2141.20ENCSR000AEF
HepG2SFXN4ENSG00000183605.1624.7634.4829.62ENCSR985KAT
K562SFXN4ENSG00000183605.1636.0136.7536.38ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SFXN4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SFXN4 RNA is bound by 13 proteins.  







eCLIP assay for SFXN4 is not avaliable on ENCORE database.





13 proteins are bound to SFXN4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10120900680120900742-3'-UTR,intron-Distal,intron-Proximal3.902073.38244K562NOLC1
chr10120920426120920439-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.347413.05161HepG2PPIG
chr10120900525120900587-3'-UTR,intron-Distal4.239918.74356HepG2GRSF1
chr10120919173120919279-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.453186.00776K562PRPF8
chr10120900685120900784-3'-UTR,CDS,intron-Distal,intron-Proximal3.713917.65013K562PABPC4
chr10120900643120900738-3'-UTR,intron-Distal,intron-Proximal4.587765.29820HepG2LSM11
chr10120920446120920494-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.660114.21358HepG2U2AF2
chr10120900671120900743-3'-UTR,intron-Distal,intron-Proximal6.0772411.21418HepG2SUB1
chr10120900503120900525-3'-UTR,intron-Distal4.911356.67223HepG2GRSF1
chr10120921854120921885-5'-UTR,CDS,intron-Distal3.366864.91258K562YBX3
chr10120921843120921883-5'-UTR,CDS,intron-Distal,intron-Proximal3.662324.68902HepG2PPIG
chr10120917184120917246-CDS,intron-Distal,intron-Proximal3.7988710.52461K562YBX3
chr10120919229120919243-CDS,intron-Distal,intron-Proximal3.653076.87160K562AQR
chr10120917257120917385-CDS,intron-Distal,intron-Proximal4.448846.13339K562KHSRP
chr10120917520120917531-CDS,intron-Distal,intron-Proximal3.276225.79072K562YBX3
chr10120914585120914679-CDS,intron-Distal,intron-Proximal3.597845.91405HepG2BCLAF1
chr10120917387120917434-CDS,intron-Distal,intron-Proximal3.474703.59112HepG2PPIG
chr10120914652120914689-CDS,intron-Distal,intron-Proximal3.176534.24993HepG2PPIG
chr10120921798120921849-intron-Distal,intron-Proximal3.459984.83899HepG2PRPF8
chr10120919186120919229-intron-Distal,intron-Proximal4.3261210.54823K562AQR
chr10120916544120916648-intron-Distal3.242493.93901K562KHSRP
chr10120918984120919079-intron-Distal5.237887.98391HepG2HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SFXN4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SFXN4 is not available on ENCORE database.

  • 76 RBPs can affect the levels of SFXN4.  








The Knockdown/knockout RNA-Seq assay for SFXN4 is not available on ENCORE database.





76 RBPs can affect the gene expression of SFXN4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SFXN4ENSG00000183605.12599.97800814.25880-0.440604.855803.98730HepG2AUH
SFXN4ENSG00000183605.12342.86710242.461100.499802.568701.98930HepG2BOP1
SFXN4ENSG00000183605.12496.21970694.99050-0.486003.216602.38530HepG2CIRBP
SFXN4ENSG00000183605.12638.93450846.88310-0.406502.508501.91070HepG2DDX3X
SFXN4ENSG00000183605.12336.40900438.06000-0.380902.418801.77830HepG2DKC1
SFXN4ENSG00000183605.12219.03010333.74950-0.607604.874804.04840HepG2DNAJC2
SFXN4ENSG00000183605.12450.39090699.35220-0.634804.941504.16130HepG2EIF2S1
SFXN4ENSG00000183605.12539.47700772.84030-0.518603.331402.63130HepG2EIF4A3
SFXN4ENSG00000183605.12668.45560934.87090-0.483906.088105.25570HepG2ETF1
SFXN4ENSG00000183605.12608.58820779.84240-0.357702.096401.49120HepG2FXR1
SFXN4ENSG00000183605.12427.39800723.37660-0.759206.593305.58860HepG2G3BP1
SFXN4ENSG00000183605.12503.92590768.01130-0.607904.913603.71660HepG2G3BP2
SFXN4ENSG00000183605.12150.57170251.86920-0.742203.738002.68190HepG2GEMIN5
SFXN4ENSG00000183605.12199.40810339.99200-0.769804.894504.06790HepG2HNRNPA1
SFXN4ENSG00000183605.12229.93350378.16400-0.717804.689303.80250HepG2HNRNPC
SFXN4ENSG00000183605.12339.00650426.23310-0.330302.113801.48020HepG2HNRNPF
SFXN4ENSG00000183605.12535.75590732.58120-0.451403.070402.33630HepG2HNRNPK
SFXN4ENSG00000183605.12488.10340593.61410-0.282301.991401.40790HepG2HNRNPL
SFXN4ENSG00000183605.12347.94280260.871900.415402.318101.44670HepG2HNRNPM
SFXN4ENSG00000183605.12407.29460735.28180-0.852208.295607.19210HepG2IGF2BP2
SFXN4ENSG00000183605.12528.43380780.11500-0.562004.224003.41650HepG2MAGOH
SFXN4ENSG00000183605.12480.62470802.93650-0.740406.550405.59420HepG2NCBP2
SFXN4ENSG00000183605.12238.03070424.37480-0.834202.076101.32350HepG2PABPC1
SFXN4ENSG00000183605.12493.38090715.01940-0.535303.745702.91420HepG2PABPC4
SFXN4ENSG00000183605.12543.67350772.23200-0.506305.923905.08930HepG2PCBP1
SFXN4ENSG00000183605.12375.49300287.539600.384902.310401.59630HepG2PRPF4
SFXN4ENSG00000183605.12352.32390785.76380-1.1572023.3606022.06500HepG2PTBP1
SFXN4ENSG00000183605.12371.12400616.87450-0.733107.045206.15100HepG2PUF60
SFXN4ENSG00000183605.12789.00240654.856100.268802.654102.07040HepG2PUM1
SFXN4ENSG00000183605.12517.83900654.36740-0.337602.155801.56100HepG2PUM2
SFXN4ENSG00000183605.12290.25610466.38690-0.684206.055305.20710HepG2PUS1
SFXN4ENSG00000183605.12586.37940851.02540-0.537405.794204.93810HepG2QKI
SFXN4ENSG00000183605.12548.54020375.720900.545802.158201.52980HepG2RAVER1
SFXN4ENSG00000183605.12487.71220781.38060-0.680007.935907.16350HepG2RBM22
SFXN4ENSG00000183605.12504.93510772.35130-0.613206.242405.26630HepG2RBM25
SFXN4ENSG00000183605.12379.96140874.48900-1.2026025.3824024.07370HepG2NELFE
SFXN4ENSG00000183605.12427.38980814.45080-0.9303016.3469015.05380HepG2RECQL
SFXN4ENSG00000183605.12176.69880275.25970-0.639503.462702.78340HepG2RPS19
SFXN4ENSG00000183605.12575.51350818.10160-0.507405.823905.01920HepG2SF3B4
SFXN4ENSG00000183605.12563.77340882.54330-0.646609.416808.64280HepG2SRFBP1
SFXN4ENSG00000183605.12370.46960853.91280-1.2047026.3209025.18750HepG2SRSF1
SFXN4ENSG00000183605.12475.42110609.09350-0.357502.667602.05010HepG2SRSF5
SFXN4ENSG00000183605.12527.38860694.69650-0.397503.951503.31560HepG2SRSF9
SFXN4ENSG00000183605.12625.98320766.26110-0.291702.369101.88700HepG2SSB
SFXN4ENSG00000183605.12287.34370436.86920-0.604402.852002.16580HepG2SUPV3L1
SFXN4ENSG00000183605.12562.33610767.50740-0.448704.340303.66200HepG2TAF15
SFXN4ENSG00000183605.12495.08670705.25880-0.510504.587703.51930HepG2TIA1
SFXN4ENSG00000183605.12397.87990258.088900.624404.210003.27310HepG2UCHL5
SFXN4ENSG00000183605.12439.89730314.334300.484803.583402.91710HepG2UTP3
SFXN4ENSG00000183605.12161.40100283.76250-0.814006.310405.36370HepG2ZC3H8
SFXN4ENSG00000183605.12543.469601189.14330-1.1297018.0620016.72930K562AQR
SFXN4ENSG00000183605.12386.54480572.29290-0.566104.087602.96100K562EFTUD2
SFXN4ENSG00000183605.12244.67850377.02030-0.623803.727602.73140K562FMR1
SFXN4ENSG00000183605.12226.25100319.56840-0.498202.408601.55970K562FTO
SFXN4ENSG00000183605.12262.23950353.74870-0.431802.125901.42670K562GPKOW
SFXN4ENSG00000183605.12313.86590566.38890-0.851608.658807.65340K562HNRNPC
SFXN4ENSG00000183605.12363.17250505.84760-0.478003.078401.86790K562HNRNPF
SFXN4ENSG00000183605.12288.21110422.33460-0.551303.905501.66050K562HNRNPH1
SFXN4ENSG00000183605.12709.32390450.324000.655405.196903.87410K562HNRNPM
SFXN4ENSG00000183605.121081.66460742.150800.543405.197104.12270K562HSPD1
SFXN4ENSG00000183605.12402.58550574.57820-0.513203.411101.74680K562LIN28B
SFXN4ENSG00000183605.12664.99280842.03040-0.340502.645701.76080K562MBNL1
SFXN4ENSG00000183605.12500.41360612.39100-0.291302.236601.55870K562NSUN2
SFXN4ENSG00000183605.12511.35290673.30470-0.396903.015301.60060K562PCBP1
SFXN4ENSG00000183605.12353.71710510.48830-0.529303.179402.28700K562PCBP3
SFXN4ENSG00000183605.12265.55240391.57640-0.560303.606602.68530K562POLR2G
SFXN4ENSG00000183605.12365.53130507.84410-0.474403.282402.28530K562PSIP1
SFXN4ENSG00000183605.121151.266101405.47890-0.287802.811101.84450K562PUM2
SFXN4ENSG00000183605.12555.42380702.48700-0.338902.104901.61890K562PUS1
SFXN4ENSG00000183605.12547.52670684.35000-0.321801.847701.34550K562RBM15
SFXN4ENSG00000183605.12481.20160641.77840-0.415402.843801.99080K562RBM22
SFXN4ENSG00000183605.12333.42580475.00450-0.510603.527302.00300K562RBM25
SFXN4ENSG00000183605.12432.16680604.24940-0.483604.365503.35920K562SF3A3
SFXN4ENSG00000183605.12235.63880336.46120-0.513902.273901.40210K562SF3B1
SFXN4ENSG00000183605.12413.50090520.71720-0.332602.041501.30850K562SF3B4
SFXN4ENSG00000183605.12293.27850439.30550-0.583003.732802.49140K562SRFBP1
SFXN4ENSG00000183605.12488.42460619.06440-0.342002.846601.90040K562SRPK2
SFXN4ENSG00000183605.12333.22380656.07930-0.9774012.7040011.18640K562SRSF1
SFXN4ENSG00000183605.12372.28390539.16720-0.534303.218002.11820K562SUPV3L1
SFXN4ENSG00000183605.12502.55930664.01570-0.401902.568401.88440K562TARDBP
SFXN4ENSG00000183605.12346.02000488.45110-0.497402.828101.88180K562TIAL1
SFXN4ENSG00000183605.12350.33340519.00820-0.567004.297003.06020K562TRIM56
SFXN4ENSG00000183605.12317.07700485.43670-0.614403.868602.53140K562U2AF1
SFXN4ENSG00000183605.12374.68200501.30520-0.420002.834202.02070K562U2AF2
SFXN4ENSG00000183605.12400.97430570.66200-0.509103.331202.20670K562UCHL5
SFXN4ENSG00000183605.12480.36600712.10490-0.568002.542201.32370K562UTP18
SFXN4ENSG00000183605.12372.81600555.61320-0.575604.902203.72040K562WDR3
SFXN4ENSG00000183605.12320.75190577.75880-0.8490012.5307010.88880K562WDR43
SFXN4ENSG00000183605.121084.829301408.81370-0.377003.530202.06220K562WRN
SFXN4ENSG00000183605.121065.891601339.65960-0.329802.663401.81930K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SFXN4 is not available on ENCORE database.





11 RBPs can affect the splicing of SFXN4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004241209008311209057471209058650.051000.001240.08822includedHepG2G3BP1
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004241209008311209057471209058650.138000.000000.00000includedK562SRSF1
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004241209008311209057471209058650.068000.000140.04069includedK562PCBP1
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004241209008311209057471209058650.085000.000000.00001includedK562AQR
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004241209008311209057471209058650.109000.000200.02140includedK562SUPV3L1
SESFXN4ENSG00000183605.12chr10-120919239120919265120917520120917574120920426120920481-0.080000.000660.01617excludedK562U2AF1
SESFXN4ENSG00000183605.12chr10-1209017641209018851209007671209008311209057471209058650.098000.000020.00090includedHepG2SRSF1
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004241209008311209057471209058650.091000.000180.02421includedHepG2SUPV3L1
SESFXN4ENSG00000183605.12chr10-1209017641209018851209007671209008311209057471209058650.091000.000060.03371includedHepG2BCCIP
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004411209008311209057471209058650.084000.000010.00105includedK562TARDBP
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004241209008311209057471209058650.089000.000230.05347includedHepG2FUS
SESFXN4ENSG00000183605.12chr10-1209017641209018851209004241209008311209057471209058650.076000.000000.00005includedK562HNRNPC
RISFXN4ENSG00000183605.12chr10-1209204261209206151209204261209204811209205661209206150.142000.001680.07545includedHepG2HNRNPA1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SFXN4 is not avaliable on ENCORE database.