SDK1

General Information

Gene Name       : SDK1
Gene ID             : ENSG00000146555.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SDK1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SDK1ENSG00000146555.180.000.000.00ENCSR000AEF
HepG2SDK1ENSG00000146555.183.351.812.58ENCSR985KAT
K562SDK1ENSG00000146555.180.000.000.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SDK1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SDK1 RNA is bound by 11 proteins.  







eCLIP assay for SDK1 is not avaliable on ENCORE database.





11 proteins are bound to SDK1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr743069064307005+3'-UTR,intron-Distal4.816755.41368HepG2PTBP1
chr743069224307045+3'-UTR,intron-Distal5.654408.60492HepG2PCBP2
chr736817013681762+CDS,intron-Proximal3.406383.68471HepG2BCLAF1
chr734981873498236+intron-Distal3.214503.69184HepG2SUGP2
chr741233154123365+intron-Distal3.346763.84798HepG2MATR3
chr734967833496855+intron-Distal4.823326.79824HepG2HNRNPM
chr742887434288820+intron-Distal4.730543.18269HepG2XPO5
chr734783343478409+intron-Distal3.280445.50064HepG2PTBP1
chr734964803496531+intron-Distal4.765555.84463HepG2SUGP2
chr735279023527989+intron-Distal3.299783.30286HepG2PTBP1
chr734731243473187+intron-Distal4.368884.74221HepG2PTBP1
chr733614413361508+intron-Distal5.8753515.07938HepG2PTBP1
chr734973193497344+intron-Distal4.035273.54208HepG2SUGP2
chr734164903416584+intron-Distal5.3503427.58041HepG2PTBP1
chr733450723345142+intron-Distal4.511283.55640HepG2QKI
chr742883964288475+intron-Distal6.0857617.46553HepG2HNRNPL
chr734010153401121+intron-Distal3.629854.89779HepG2PTBP1
chr733883673388430+intron-Distal4.178624.24478HepG2CSTF2
chr742883134288361+intron-Distal3.973113.33101HepG2AGGF1
chr734963763496436+intron-Distal4.901035.42507HepG2MATR3
chr742881914288256+intron-Distal5.316676.36545HepG2HNRNPL
chr735010763501178+intron-Distal3.098843.27745HepG2SUGP2
chr734967623496837+intron-Distal4.525979.80337HepG2SUGP2
chr733951733395255+intron-Distal3.017284.21501HepG2MATR3
chr742887414288820+intron-Distal4.918903.32571HepG2AGGF1
chr735203733520437+intron-Distal4.945657.03187HepG2CSTF2
chr742879484287995+intron-Distal3.819053.33101HepG2AGGF1
chr734959323495968+intron-Distal4.325705.04879HepG2SUGP2
chr734355663435658+intron-Distal4.464555.04769HepG2PTBP1
chr734967583496870+intron-Distal4.6278810.19844HepG2MATR3
chr742877874287824+intron-Distal3.581365.35988HepG2HNRNPL
chr739375173937638+intron-Distal4.7338811.90381HepG2PTBP1
chr742883024288361+intron-Distal4.912065.84190HepG2HNRNPL
chr734977603497829+intron-Distal4.576484.60209HepG2MATR3
chr735466963546774+intron-Distal3.151733.59523HepG2SUGP2
chr733614453361535+intron-Distal5.306387.79030HepG2PCBP2
chr741233044123374+intron-Distal6.1939318.08872HepG2PCBP2
chr734570813457153+intron-Distal4.782405.41368HepG2PTBP1
chr735476463547739+intron-Distal4.625825.41368HepG2PTBP1
chr739942123994273+intron-Distal4.291934.32196HepG2PCBP2
chr735148523514953+intron-Distal4.297803.96879HepG2MATR3
chr735398973539986+intron-Distal4.540654.51299HepG2SUGP2
chr738960523896115+intron-Distal4.294804.05848HepG2QKI
chr735408153540900+intron-Distal4.145233.27829HepG2MATR3
chr737056133705686+intron-Distal3.724053.04224HepG2SUGP2
chr736832563683309+intron-Distal4.591193.78681HepG2PCBP2
chr737360673736164+intron-Distal4.709844.05848HepG2QKI
chr740094404009607+intron-Distal5.040374.80665HepG2QKI
chr734965653496630+intron-Distal3.384548.28385HepG2SUGP2
chr735022493502376+intron-Distal4.007303.41738HepG2PTBP1
chr734406463440697+intron-Distal4.496793.85055HepG2XPO5
chr742879324288070+intron-Distal3.398443.84024HepG2HNRNPL
chr734954433495513+intron-Distal3.640287.51551HepG2SUGP2
chr735023913502499+intron-Distal4.893046.10726HepG2SUGP2
chr735007073500791+intron-Distal3.472514.57452HepG2SUGP2
chr733833643383468+intron-Distal4.116324.47016HepG2CSTF2
chr734965813496626+intron-Distal4.459255.15027HepG2MATR3
chr734921573492283+intron-Distal5.248259.73701HepG2QKI
chr741233104123372+intron-Distal5.486988.66996HepG2PTBP1
chr734977213497828+intron-Distal3.465758.52173HepG2SUGP2
chr734951343495172+intron-Distal4.246253.79098HepG2SUGP2
chr734943843494506+intron-Distal3.994046.25619HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SDK1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SDK1 is not available on ENCORE database.

  • 80 RBPs can affect the levels of SDK1.  








The Knockdown/knockout RNA-Seq assay for SDK1 is not available on ENCORE database.





80 RBPs can affect the gene expression of SDK1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SDK1ENSG00000146555.141267.86280566.672701.1617014.8593013.72650HepG2AKAP1
SDK1ENSG00000146555.14531.79600228.614901.2179019.0607017.30420HepG2AKAP8L
SDK1ENSG00000146555.14867.95280468.857200.888409.686308.27250HepG2ASCC1
SDK1ENSG00000146555.14365.48580248.014100.559304.239803.42200HepG2AUH
SDK1ENSG00000146555.14197.26250300.45860-0.607002.220301.38480HepG2BCCIP
SDK1ENSG00000146555.1485.43510135.96270-0.670302.184201.64730HepG2BOP1
SDK1ENSG00000146555.14377.29180211.903000.832204.497602.94850HepG2BUD13
SDK1ENSG00000146555.14206.58850124.816900.726803.206902.47240HepG2CPSF6
SDK1ENSG00000146555.14349.21270232.899400.584302.999101.85200HepG2CPSF7
SDK1ENSG00000146555.14490.21070383.648200.353502.224901.31460HepG2YBX3
SDK1ENSG00000146555.14731.10050530.038400.463904.570903.78120HepG2CELF1
SDK1ENSG00000146555.14961.31840569.944200.754109.390808.14980HepG2DAZAP1
SDK1ENSG00000146555.14514.30750384.166100.420802.913501.72750HepG2DDX1
SDK1ENSG00000146555.14141.25510476.26910-1.7535025.2592023.50000HepG2DDX21
SDK1ENSG00000146555.14267.01230466.45750-0.804807.190105.72470HepG2DDX24
SDK1ENSG00000146555.14388.02200542.79340-0.484302.743002.11820HepG2DDX3X
SDK1ENSG00000146555.14761.63180978.62710-0.361702.660701.38660HepG2DDX47
SDK1ENSG00000146555.14252.75220141.740100.834403.247702.19110HepG2DDX59
SDK1ENSG00000146555.141518.50590466.356001.7030032.0621030.29720HepG2DDX6
SDK1ENSG00000146555.14121.47800217.73230-0.841904.945704.08870HepG2DKC1
SDK1ENSG00000146555.14481.97130376.689200.355502.312901.66410HepG2DNAJC21
SDK1ENSG00000146555.14299.84570438.90450-0.549702.797501.68570HepG2AGO1
SDK1ENSG00000146555.14804.32030448.234700.843408.488807.48830HepG2EIF2S1
SDK1ENSG00000146555.14648.14060484.045700.421102.128901.32730HepG2EIF3D
SDK1ENSG00000146555.14760.08150562.265400.434802.496401.69320HepG2EIF4G1
SDK1ENSG00000146555.14956.38670538.617700.8282010.025708.52260HepG2EIF4G2
SDK1ENSG00000146555.14704.87940432.686800.704008.134906.11170HepG2FAM120A
SDK1ENSG00000146555.14606.14580407.903000.571304.397403.41940HepG2FUBP3
SDK1ENSG00000146555.14628.26420463.639400.438302.483001.85100HepG2G3BP1
SDK1ENSG00000146555.1466.71130141.47800-1.084604.163503.38960HepG2GPKOW
SDK1ENSG00000146555.14302.74970217.252300.478702.943001.93990HepG2HDGF
SDK1ENSG00000146555.14233.00150380.29840-0.706804.515003.71620HepG2HNRNPA1
SDK1ENSG00000146555.14284.12630423.02350-0.574203.445702.67750HepG2HNRNPC
SDK1ENSG00000146555.14716.74030469.629100.609804.966704.05150HepG2HNRNPK
SDK1ENSG00000146555.14850.01840519.182500.7112012.4766011.13970HepG2HNRNPL
SDK1ENSG00000146555.14719.36540471.256200.610104.599103.74840HepG2IGF2BP2
SDK1ENSG00000146555.14566.54060429.244700.400304.006603.14090HepG2ILF2
SDK1ENSG00000146555.14854.22710474.046500.849506.963805.29050HepG2KHSRP
SDK1ENSG00000146555.14398.83960208.013600.9390011.263109.34970HepG2KIF1C
SDK1ENSG00000146555.14309.36530500.04710-0.692804.799303.94300HepG2MAGOH
SDK1ENSG00000146555.14133.93600231.10890-0.787004.495103.48130HepG2MSI2
SDK1ENSG00000146555.14241.68860137.724400.811302.939301.93720HepG2MTPAP
SDK1ENSG00000146555.14414.43870194.093001.0943010.921608.54790HepG2NAA15
SDK1ENSG00000146555.14535.66380364.819400.554003.836902.14840HepG2NIP7
SDK1ENSG00000146555.14876.67120458.257300.9358010.574609.18390HepG2PABPC4
SDK1ENSG00000146555.14374.70520486.46190-0.376602.582601.99080HepG2PCBP1
SDK1ENSG00000146555.14719.80140374.805800.9414011.271709.84040HepG2PPIL4
SDK1ENSG00000146555.14890.00110572.263800.637005.296604.38300HepG2PUM2
SDK1ENSG00000146555.14122.65840231.81270-0.918305.288504.48670HepG2PUS1
SDK1ENSG00000146555.14673.26850536.063000.328702.304401.72460HepG2QKI
SDK1ENSG00000146555.14561.66510319.559900.813508.826207.41000HepG2RBM15
SDK1ENSG00000146555.14141.62300237.99340-0.748903.920503.33190HepG2RBM22
SDK1ENSG00000146555.14733.45650486.532200.592104.395403.56150HepG2RBM25
SDK1ENSG00000146555.14697.45990550.887000.340302.712102.17530HepG2NELFE
SDK1ENSG00000146555.14736.73670513.114900.521805.813204.96260HepG2RECQL
SDK1ENSG00000146555.1490.74110165.03610-0.863003.465202.71410HepG2RPLP0
SDK1ENSG00000146555.14321.88500471.03420-0.549303.902403.18390HepG2RPS19
SDK1ENSG00000146555.14324.76120448.70920-0.466402.701701.90960HepG2RPS2
SDK1ENSG00000146555.14308.87320554.55180-0.844302.404501.65620HepG2RPS3A
SDK1ENSG00000146555.14338.22060225.283400.586102.291201.56920HepG2RRP9
SDK1ENSG00000146555.14637.62080374.222700.7687011.1956010.03610HepG2SAFB2
SDK1ENSG00000146555.14158.70270333.72280-1.072307.707806.54320HepG2SF3A3
SDK1ENSG00000146555.14903.95430517.264800.8052015.9349014.50520HepG2SLBP
SDK1ENSG00000146555.14483.59160268.809300.847109.673508.89250HepG2SRFBP1
SDK1ENSG00000146555.14224.55000537.91430-1.2603018.5846017.58630HepG2SRSF1
SDK1ENSG00000146555.14248.25920143.808200.787603.511902.37100HepG2SRSF3
SDK1ENSG00000146555.14724.61330532.651900.443904.482003.71970HepG2SRSF5
SDK1ENSG00000146555.141042.44270437.638001.2521036.4461034.87710HepG2SRSF9
SDK1ENSG00000146555.14842.19700605.779600.475305.754204.91750HepG2SUCLG1
SDK1ENSG00000146555.14198.37250294.06330-0.567902.418401.78090HepG2SUPV3L1
SDK1ENSG00000146555.14622.11610483.550200.363402.872902.30200HepG2TAF15
SDK1ENSG00000146555.14593.10760444.261700.416803.097902.21910HepG2TIA1
SDK1ENSG00000146555.14212.97530408.28340-0.938909.199808.38080HepG2TIAL1
SDK1ENSG00000146555.14751.77590411.980900.8676015.3689014.18980HepG2TRIM56
SDK1ENSG00000146555.14844.09030527.039800.679407.648506.08550HepG2TUFM
SDK1ENSG00000146555.14131.70820244.33420-0.891503.391302.70130HepG2U2AF1
SDK1ENSG00000146555.14854.57650557.855400.615204.429803.35340HepG2UBE2L3
SDK1ENSG00000146555.14113.68180173.68190-0.611402.403401.69540HepG2UCHL5
SDK1ENSG00000146555.14120.38070285.73890-1.2471011.4377010.35210HepG2UTP3
SDK1ENSG00000146555.141020.42180325.500601.6483060.1992058.52280HepG2ZNF622
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SDK1 is not available on ENCORE database.





1 RBPs can affect the splicing of SDK1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RISDK1ENSG00000146555.14chr7+4304755430863243047554304880430830943086320.201000.008760.09942includedHepG2SRSF9

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SDK1 is not avaliable on ENCORE database.