PYCR2

General Information

Gene Name       : PYCR2
Gene ID             : ENSG00000143811.18
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PYCR2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PYCR2ENSG00000143811.1812.0831.9922.04ENCSR000AEF
HepG2PYCR2ENSG00000143811.1849.5026.4937.99ENCSR985KAT
K562PYCR2ENSG00000143811.18134.78103.86119.32ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PYCR2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PYCR2 RNA is bound by 32 proteins.  







eCLIP assay for PYCR2 is not avaliable on ENCORE database.





32 proteins are bound to PYCR2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1226107663226107718-3'-UTR,intron-Distal3.566296.35062K562IGF2BP1
chr1226107589226107638-3'-UTR,intron-Distal3.943218.84200K562PABPC4
chr1226108030226108100-3'-UTR,intron-Distal3.852493.19668HepG2UPF1
chr1226107890226108060-3'-UTR,intron-Distal3.668235.99892HepG2LSM11
chr1226107891226108000-3'-UTR,intron-Distal3.4559812.53117K562PABPC4
chr1226108032226108067-3'-UTR,intron-Distal3.690805.68843K562DDX6
chr1226107626226107729-3'-UTR,intron-Distal3.394184.11066K562NOLC1
chr1226108031226108094-3'-UTR,intron-Distal3.732123.06617K562HNRNPK
chr1226107710226107780-3'-UTR,intron-Distal5.8140936.65816K562UPF1
chr1226107609226107710-3'-UTR,intron-Distal3.9803630.78893K562UPF1
chr1226108043226108150-3'-UTR,intron-Distal3.035856.07255K562PCBP1
chr1226107603226107644-3'-UTR,intron-Distal4.7849171.61685K562PUM2
chr1226107790226107939-3'-UTR,intron-Distal5.188188.19969HepG2UPF1
chr1226107644226107664-3'-UTR,intron-Distal5.47071400.00000K562PUM2
chr1226107886226107980-3'-UTR,intron-Distal3.9223920.23183K562UPF1
chr1226107664226107721-3'-UTR,intron-Distal5.63798400.00000K562PUM2
chr1226108015226108092-3'-UTR,intron-Distal3.9080110.66732K562PABPC4
chr1226107607226107663-3'-UTR,intron-Distal4.196626.14589K562IGF2BP1
chr1226107606226107676-3'-UTR,intron-Distal4.526777.36168HepG2SUB1
chr1226107772226107855-3'-UTR,intron-Distal3.4127624.25590K562DDX6
chr1226107780226107881-3'-UTR,intron-Distal5.4748761.66621K562UPF1
chr1226108022226108112-3'-UTR,intron-Distal3.564349.04863K562IGF2BP2
chr1226111879226111950-5'-UTR,intron-Distal3.521317.78729K562GEMIN5
chr1226111787226111855-5'-UTR,CDS,intron-Distal,intron-Proximal3.131036.38429K562DROSHA
chr1226111807226111861-5'-UTR,CDS,intron-Distal3.7490914.91304K562RPS3
chr1226111739226111857-5'-UTR,CDS,intron-Distal,intron-Proximal3.440584.02244HepG2NCBP2
chr1226111807226111927-5'-UTR,CDS,intron-Distal3.770828.14916K562PCBP1
chr1226111741226111786-CDS,intron-Distal,intron-Proximal3.076435.21025HepG2PPIG
chr1226109899226109977-CDS,intron-Distal,intron-Proximal3.064837.16368HepG2PPIG
chr1226109052226109229-CDS,intron-Distal,intron-Proximal3.7812718.13480K562EFTUD2
chr1226111753226111807-CDS,intron-Distal,intron-Proximal4.222479.79608K562RPS3
chr1226111339226111405-CDS,intron-Distal,intron-Proximal3.293863.93112K562RBM15
chr1226109208226109253-CDS,intron-Distal,intron-Proximal5.0696117.02742K562AQR
chr1226111433226111489-CDS,intron-Distal,intron-Proximal5.9205848.07933K562AQR
chr1226111424226111570-CDS,intron-Distal,intron-Proximal5.413898.16909HepG2AQR
chr1226111415226111438-CDS,intron-Distal4.2710520.91460K562YBX3
chr1226109918226110006-CDS,intron-Distal4.2288530.65807K562RPS3
chr1226111357226111435-CDS,intron-Distal,intron-Proximal4.4752317.37257HepG2PRPF8
chr1226111405226111414-CDS,intron-Distal4.1637919.73995K562YBX3
chr1226111467226111471-CDS,intron-Distal3.562269.40778K562YBX3
chr1226108214226108269-CDS,intron-Distal3.989525.24350K562PCBP1
chr1226108292226108364-CDS,intron-Distal3.492115.75231K562AQR
chr1226111744226111787-CDS,intron-Distal,intron-Proximal3.0161913.57305K562DDX3X
chr1226111739226111745-CDS,intron-Distal,intron-Proximal4.0000612.23507HepG2PRPF8
chr1226110043226110143-CDS,intron-Distal,intron-Proximal3.604433.39008HepG2AQR
chr1226111348226111420-CDS,intron-Distal,intron-Proximal3.210144.90382K562DDX6
chr1226111429226111496-CDS,intron-Distal,intron-Proximal3.823075.88049HepG2EFTUD2
chr1226109039226109126-CDS,intron-Distal,intron-Proximal3.7473510.35072HepG2BUD13
chr1226109051226109171-CDS,intron-Distal,intron-Proximal4.9524311.08778HepG2AQR
chr1226110062226110109-CDS,intron-Distal,intron-Proximal3.6530712.26379K562AQR
chr1226111364226111417-CDS,intron-Distal,intron-Proximal4.624755.68078HepG2AQR
chr1226108919226108947-CDS,intron-Distal,intron-Proximal3.152705.33443K562IGF2BP2
chr1226111677226111749-CDS,intron-Distal,intron-Proximal5.6085410.68826HepG2AQR
chr1226109566226109727-CDS,intron-Distal,intron-Proximal4.012743.89619HepG2SRSF1
chr1226109048226109128-CDS,intron-Distal,intron-Proximal4.0584315.34537K562SF3B4
chr1226109038226109101-CDS,intron-Distal,intron-Proximal4.2036816.19797K562BUD13
chr1226109749226109830-CDS,intron-Distal,intron-Proximal4.9453017.69310K562SF3B4
chr1226111455226111467-CDS,intron-Distal3.6750010.50401K562YBX3
chr1226109906226110015-CDS,intron-Distal4.204866.04229K562RBM15
chr1226109636226109746-CDS,intron-Distal,intron-Proximal3.411786.75249K562LIN28B
chr1226111743226111747-CDS,intron-Distal,intron-Proximal3.9938614.57262K562YBX3
chr1226111747226111754-CDS,intron-Distal,intron-Proximal3.173139.81901K562YBX3
chr1226111754226111764-CDS,intron-Distal,intron-Proximal3.7208818.36337K562YBX3
chr1226111441226111491-CDS,intron-Distal,intron-Proximal3.1419315.02844K562PRPF8
chr1226111438226111453-CDS,intron-Distal3.9040515.15144K562YBX3
chr1226110071226110164-CDS,intron-Distal,intron-Proximal3.132763.33980HepG2SF3B4
chr1226109707226109745-CDS,intron-Distal,intron-Proximal3.517934.13746HepG2PPIG
chr1226109771226109840-CDS,intron-Distal,intron-Proximal3.436603.84691HepG2SF3B4
chr1226109039226109116-CDS,intron-Distal,intron-Proximal5.5321231.35979K562AQR
chr1226111604226111664-intron-Distal,intron-Proximal5.3888924.96343K562AQR
chr1226111739226111744-intron-Distal,intron-Proximal6.5446371.31765K562AQR
chr1226111664226111688-intron-Distal,intron-Proximal5.5770719.62251K562AQR
chr1226111682226111685-intron-Distal,intron-Proximal4.204033.32446HepG2PRPF8
chr1226111599226111653-intron-Distal,intron-Proximal3.200304.05481K562BUD13
chr1226110477226110537-intron-Distal4.507675.98323K562DROSHA
chr1226110092226110172-intron-Distal,intron-Proximal3.305613.64169K562XRN2
chr1226111707226111739-intron-Distal,intron-Proximal6.05211400.00000K562AQR
chr1226111599226111662-intron-Distal,intron-Proximal4.8000412.24889HepG2PRPF8
chr1226109074226109136-intron-Distal,intron-Proximal3.749474.60097HepG2EFTUD2
chr1226109445226109496-intron-Distal,intron-Proximal4.796205.80866K562BUD13
chr1226109214226109249-intron-Distal,intron-Proximal3.564383.88924K562PRPF8
chr1226109149226109238-intron-Distal,intron-Proximal3.418336.80457K562GPKOW
chr1226110512226110579-intron-Distal3.652723.37821K562XRCC6
chr1226109116226109163-intron-Distal,intron-Proximal4.7965211.83800K562AQR
chr1226111489226111632-intron-Distal,intron-Proximal3.028325.23694K562FUS
chr1226109115226109167-intron-Distal,intron-Proximal3.824228.66868K562BUD13
chr1226109074226109138-intron-Distal,intron-Proximal3.833023.20724K562SMNDC1
chr1226108868226108906-intron-Distal,intron-Proximal5.473858.88118K562AQR
chr1226111381226111400-intron-Distal,intron-Proximal5.2775414.81877K562AQR
chr1226111607226111652-intron-Distal,intron-Proximal3.867883.53160K562RBFOX2
chr1226111706226111736-intron-Distal,intron-Proximal4.091944.32762K562GEMIN5
chr1226111353226111381-intron-Distal,intron-Proximal6.5635920.63385K562AQR
chr1226111699226111730-intron-Distal,intron-Proximal3.601989.87196K562PRPF8
chr1226111675226111720-intron-Distal,intron-Proximal3.222426.93851K562BUD13
chr1226111690226111726-intron-Distal,intron-Proximal5.0680420.50766HepG2PRPF8
chr1226111688226111707-intron-Distal,intron-Proximal6.27993400.00000K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PYCR2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PYCR2 is not available on ENCORE database.

  • 61 RBPs can affect the levels of PYCR2.  








The Knockdown/knockout RNA-Seq assay for PYCR2 is not available on ENCORE database.





61 RBPs can affect the gene expression of PYCR2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PYCR2ENSG00000143811.121037.139401354.74560-0.385404.970704.09410HepG2AUH
PYCR2ENSG00000143811.12435.55930617.23860-0.503004.030603.12250HepG2CALR
PYCR2ENSG00000143811.12414.87120531.93390-0.358602.133501.34180HepG2DDX24
PYCR2ENSG00000143811.121149.40910747.266600.621105.092004.27680HepG2DDX6
PYCR2ENSG00000143811.12450.52160574.48490-0.350702.112201.41750HepG2FUBP3
PYCR2ENSG00000143811.121063.14920752.548800.498404.209003.36300HepG2HNRNPK
PYCR2ENSG00000143811.121034.14670801.246000.368002.269901.67340HepG2MAGOH
PYCR2ENSG00000143811.12421.09530561.65080-0.415502.370101.67600HepG2NSUN2
PYCR2ENSG00000143811.12810.67970984.38830-0.280101.930401.36410HepG2PUM2
PYCR2ENSG00000143811.12939.395801300.07300-0.468806.034905.34300HepG2RBM22
PYCR2ENSG00000143811.12497.64030754.07410-0.599603.304402.56790HepG2RPLP0
PYCR2ENSG00000143811.12372.30120545.38850-0.550803.056602.23660HepG2RRP9
PYCR2ENSG00000143811.12745.60730322.428401.209304.042402.32990HepG2SF1
PYCR2ENSG00000143811.12724.01730313.352501.208103.727701.98230HepG2SFPQ
PYCR2ENSG00000143811.12722.18120504.601400.517102.990501.99050HepG2SMNDC1
PYCR2ENSG00000143811.12990.339301468.37170-0.5682011.1000010.27760HepG2SRFBP1
PYCR2ENSG00000143811.12711.96860844.37990-0.246101.832101.42480HepG2SRSF1
PYCR2ENSG00000143811.12542.39780686.94980-0.340902.966302.39890HepG2SRSF9
PYCR2ENSG00000143811.121053.226801274.87170-0.275503.017802.48730HepG2SSB
PYCR2ENSG00000143811.121211.692401042.038400.217502.175601.61160HepG2SUCLG1
PYCR2ENSG00000143811.12677.61300849.40400-0.326002.094701.54050HepG2U2AF1
PYCR2ENSG00000143811.12521.57860719.22700-0.463605.312504.43160HepG2ZC3H8
PYCR2ENSG00000143811.126176.812505288.704700.223803.717703.07780K562AGGF1
PYCR2ENSG00000143811.124606.757505947.21470-0.368503.710203.05060K562AQR
PYCR2ENSG00000143811.122686.758003155.58530-0.232002.704201.41090K562BCCIP
PYCR2ENSG00000143811.122654.685503199.61440-0.269402.627001.86160K562CPSF6
PYCR2ENSG00000143811.123897.500104948.33960-0.344406.859005.89750K562DDX47
PYCR2ENSG00000143811.124141.891503278.665300.337105.048303.10320K562DDX6
PYCR2ENSG00000143811.126709.215005921.663800.180002.180601.41380K562DKC1
PYCR2ENSG00000143811.123687.280003042.516000.277203.306902.02040K562EIF4B
PYCR2ENSG00000143811.125390.789406510.04380-0.272204.544203.35220K562EIF4G2
PYCR2ENSG00000143811.124243.332303181.008500.415604.673403.55030K562FIP1L1
PYCR2ENSG00000143811.121878.787402691.83520-0.518805.263103.61400K562FKBP4
PYCR2ENSG00000143811.121963.758302759.39780-0.490704.734503.50810K562FTO
PYCR2ENSG00000143811.122957.304503513.52350-0.248603.169002.52780K562FXR1
PYCR2ENSG00000143811.12869.294501737.31030-0.998906.520805.33340K562G3BP2
PYCR2ENSG00000143811.122226.054003098.99270-0.477306.686405.79880K562HNRNPC
PYCR2ENSG00000143811.122750.918603686.60720-0.422405.372402.77870K562HNRNPH1
PYCR2ENSG00000143811.124130.803305062.34750-0.293403.513802.50790K562HNRNPU
PYCR2ENSG00000143811.124090.917702888.673400.501903.354702.18490K562IGF2BP2
PYCR2ENSG00000143811.121876.591102608.47950-0.475102.251101.41860K562KRR1
PYCR2ENSG00000143811.123682.729604193.26170-0.187302.547201.77010K562MTPAP
PYCR2ENSG00000143811.122822.125703373.71450-0.257602.625701.42730K562NCBP2
PYCR2ENSG00000143811.125674.586407121.29090-0.327603.484501.78960K562NOL12
PYCR2ENSG00000143811.122921.019803418.54180-0.226902.189201.47710K562POLR2G
PYCR2ENSG00000143811.124653.246303611.133100.365703.560102.61040K562PPIG
PYCR2ENSG00000143811.123342.324702778.678300.266402.098701.32170K562PSIP1
PYCR2ENSG00000143811.124959.337207102.81150-0.518206.942905.64710K562PUF60
PYCR2ENSG00000143811.126395.303507555.93040-0.240602.979401.86770K562PUM1
PYCR2ENSG00000143811.126019.163707402.31960-0.298405.312803.96340K562PUM2
PYCR2ENSG00000143811.123465.417802535.698100.450506.477604.95930K562RCC2
PYCR2ENSG00000143811.123774.664203046.364100.309203.131801.97890K562SAFB
PYCR2ENSG00000143811.122215.709402905.30100-0.390902.945701.94080K562SF3B1
PYCR2ENSG00000143811.122545.933301805.284100.495906.255404.93210K562SF3B4
PYCR2ENSG00000143811.123387.585202403.720800.494906.346704.61500K562SRFBP1
PYCR2ENSG00000143811.123995.078304710.09520-0.237504.598203.42580K562SRPK2
PYCR2ENSG00000143811.123665.587802890.225500.342802.825002.11190K562SRSF1
PYCR2ENSG00000143811.122941.120802093.628300.490304.581203.16850K562SRSF4
PYCR2ENSG00000143811.123671.167102730.077200.427202.666001.63920K562SRSF5
PYCR2ENSG00000143811.123841.331202821.294700.445103.237502.34240K562TIA1
PYCR2ENSG00000143811.123762.648502769.512200.442002.889001.76750K562TRA2A
PYCR2ENSG00000143811.123711.876002839.824700.386204.258403.02850K562TRIM56
PYCR2ENSG00000143811.122102.696202569.89830-0.289502.268801.35570K562UCHL5
PYCR2ENSG00000143811.123960.214704940.08960-0.319006.686505.62280K562UPF1
PYCR2ENSG00000143811.123351.628604395.70410-0.3912010.036008.54030K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PYCR2 is not available on ENCORE database.





16 RBPs can affect the splicing of PYCR2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSPYCR2ENSG00000143811.12chr1-2261099032261101382261099032261100832261114002261115890.112000.000000.00000longerK562AQR
MXEPYCR2ENSG00000143811.12chr1-2261099032261100832261114002261114712261095572261097792261117432261119590.083000.000830.097701includedK562MATR3
MXEPYCR2ENSG00000143811.12chr1-2261099032261100832261114002261114712261095572261097792261117432261119590.162000.000000.002611includedK562LARP4
MXEPYCR2ENSG00000143811.12chr1-2261092512261093442261095572261097792261089072261090712261099032261100830.082000.001290.085551includedK562HNRNPL
MXEPYCR2ENSG00000143811.12chr1-2261099032261100832261114002261114712261095572261097792261117432261119590.142000.000000.000041includedK562PTBP1
MXEPYCR2ENSG00000143811.12chr1-2261092512261093442261095572261114712261089072261090712261117432261119780.069000.000000.000001includedK562DROSHA
MXEPYCR2ENSG00000143811.12chr1-2261092512261093442261095572261097792261089072261090712261099032261100830.114000.000010.000711includedK562DROSHA
MXEPYCR2ENSG00000143811.12chr1-2261095572261097792261099032261100832261093032261093442261114002261114710.172000.004000.047371includedK562U2AF2
MXEPYCR2ENSG00000143811.12chr1-2261099032261100832261114002261114712261095572261097792261117432261119590.155000.000000.000001includedK562TARDBP
MXEPYCR2ENSG00000143811.12chr1-226109557226109779226109903226110083226109303226109344226111400226111471-0.114000.002110.071442includedK562SAFB
MXEPYCR2ENSG00000143811.12chr1-2261092512261093442261095572261114712261089072261090712261117432261119780.144000.000200.056611includedK562APOBEC3C
MXEPYCR2ENSG00000143811.12chr1-2261099032261100832261114002261114712261095572261097792261117432261119590.160000.000000.000001includedK562TIA1
MXEPYCR2ENSG00000143811.12chr1-2261099032261100832261114002261114712261095572261097792261117432261119590.147000.000000.000031includedK562IGF2BP2
MXEPYCR2ENSG00000143811.12chr1-226109251226109344226109557226109779226108921226109071226109903226110779-0.090000.007230.086722includedK562SF3B4
MXEPYCR2ENSG00000143811.12chr1-2261092512261093442261095572261097792261089072261090712261099032261100830.076000.000700.069771includedK562NPM1
MXEPYCR2ENSG00000143811.12chr1-2261099032261100832261114002261114712261095572261097792261117432261119590.103000.000300.010151includedK562SUPV3L1
MXEPYCR2ENSG00000143811.12chr1-2261099032261100832261114002261114712261095572261097792261117432261119590.151000.000020.001211includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PYCR2 is not avaliable on ENCORE database.