PFKM

General Information

Gene Name       : PFKM
Gene ID             : ENSG00000152556.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PFKM)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PFKMENSG00000152556.1636.5836.8236.70ENCSR000AEF
HepG2PFKMENSG00000152556.160.631.040.83ENCSR985KAT
K562PFKMENSG00000152556.1619.9922.2121.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PFKM is not avaliable on ENCORE database.



Proteins bound to RNA
  • PFKM RNA is bound by 3 proteins.  







eCLIP assay for PFKM is not avaliable on ENCORE database.





3 proteins are bound to PFKM RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr124852873148528914+3'-UTR,CDS,intron-Distal,intron-Proximal4.530755.52476K562BUD13
chr124853958448539675+3'-UTR4.460739.91456HepG2SUB1
chr124853979448539863+3'-UTR5.256019.39648K562PABPC4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PFKM is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PFKM is not available on ENCORE database.

  • 84 RBPs can affect the levels of PFKM.  








The Knockdown/knockout RNA-Seq assay for PFKM is not available on ENCORE database.





84 RBPs can affect the gene expression of PFKM :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PFKMENSG00000152556.11241.54480104.321301.211206.619505.83620HepG2AKAP1
PFKMENSG00000152556.11180.9136086.324501.067405.205704.14570HepG2ASCC1
PFKMENSG00000152556.11372.07760104.793101.8280027.1404025.38770HepG2AUH
PFKMENSG00000152556.11155.3403044.886201.791008.172006.73230HepG2BCLAF1
PFKMENSG00000152556.11422.9360039.987403.4027056.0477054.04640HepG2BOP1
PFKMENSG00000152556.11142.6453069.178001.043903.546702.67420HepG2CNOT7
PFKMENSG00000152556.1196.4061036.707201.393004.707303.83180HepG2CPSF6
PFKMENSG00000152556.1197.8441051.818400.916902.694202.02450HepG2DDX21
PFKMENSG00000152556.11568.0208099.947802.5066039.8798037.79000HepG2DDX3X
PFKMENSG00000152556.11137.4234041.684801.720906.929305.42430HepG2DDX59
PFKMENSG00000152556.11138.1170085.819900.686402.074001.53220HepG2DDX6
PFKMENSG00000152556.11116.8089044.546901.390706.609605.55810HepG2DNAJC21
PFKMENSG00000152556.1190.8322044.162801.040303.893603.14720HepG2DNAJC2
PFKMENSG00000152556.11211.8581082.537801.359908.229707.24520HepG2EIF2S1
PFKMENSG00000152556.11185.93520120.309200.628002.811902.20700HepG2ETF1
PFKMENSG00000152556.1195.8122049.361900.956702.967901.78630HepG2FASTKD2
PFKMENSG00000152556.11198.4850036.777202.4320011.094809.09730HepG2FTO
PFKMENSG00000152556.11360.4610085.367302.0780023.8263021.96580HepG2G3BP1
PFKMENSG00000152556.11130.7407064.023701.029903.652502.37150HepG2GRSF1
PFKMENSG00000152556.11184.7706039.701602.218405.928705.04380HepG2HNRNPLL
PFKMENSG00000152556.11103.6596049.697101.060504.228703.49240HepG2HNRNPU
PFKMENSG00000152556.1194.4737050.763400.896003.009302.24720HepG2ILF2
PFKMENSG00000152556.11157.1871067.426701.221005.329703.46550HepG2ILF3
PFKMENSG00000152556.11115.5520065.680100.814902.645301.64570HepG2KIF1C
PFKMENSG00000152556.11211.8897098.078701.111205.502003.73350HepG2KRR1
PFKMENSG00000152556.1140.6031092.55070-1.188703.320202.63490HepG2MATR3
PFKMENSG00000152556.11115.9783055.043601.075103.490702.58250HepG2MSI2
PFKMENSG00000152556.11110.2513040.510801.444302.772001.80310HepG2MTPAP
PFKMENSG00000152556.11229.7722094.737901.278107.842306.80150HepG2NCBP2
PFKMENSG00000152556.11229.9806084.403201.4460010.291908.92030HepG2PABPC4
PFKMENSG00000152556.11359.77470106.331501.7584022.9507021.66540HepG2PTBP1
PFKMENSG00000152556.11181.1019072.916701.312408.152607.02830HepG2PUM2
PFKMENSG00000152556.11547.7250073.170802.9040050.1864048.24450HepG2PUS1
PFKMENSG00000152556.11728.38000115.174002.6608066.3668064.12110HepG2QKI
PFKMENSG00000152556.11154.2274072.645501.086005.355804.21030HepG2RBM15
PFKMENSG00000152556.11164.48480100.557800.709802.956902.42660HepG2RBM22
PFKMENSG00000152556.1164.06520110.20970-0.782602.530701.93760HepG2RECQL
PFKMENSG00000152556.1149.2225089.22700-0.858202.207601.60430HepG2SF3A3
PFKMENSG00000152556.1174.3243039.291400.919502.063801.44900HepG2SF3B1
PFKMENSG00000152556.11165.80140113.579000.545701.974601.52990HepG2SRFBP1
PFKMENSG00000152556.1143.85620115.55950-1.397806.007305.37670HepG2SRSF1
PFKMENSG00000152556.11132.5524083.131700.673002.690202.00390HepG2SRSF7
PFKMENSG00000152556.11162.9307098.618200.724203.367802.81460HepG2SSB
PFKMENSG00000152556.11186.4823077.187101.272508.851107.84480HepG2SUCLG1
PFKMENSG00000152556.11310.7350099.005901.6500013.1569010.20280HepG2SUGP2
PFKMENSG00000152556.11164.4957045.923101.8407012.2637010.41320HepG2SUPT6H
PFKMENSG00000152556.1194.4919048.278600.968703.156202.62760HepG2TIAL1
PFKMENSG00000152556.1191.9981048.722400.916903.150402.55760HepG2TRIM56
PFKMENSG00000152556.11160.4765058.201501.463106.684005.71920HepG2U2AF1
PFKMENSG00000152556.11164.9699071.087401.214404.675903.56890HepG2UBE2L3
PFKMENSG00000152556.11242.3112079.130801.6144015.1133013.73310HepG2UPF1
PFKMENSG00000152556.11179.5095081.334601.142007.099505.50510HepG2UTP18
PFKMENSG00000152556.11125.9080062.146801.018503.782402.49680HepG2XPO5
PFKMENSG00000152556.11174.4830087.028601.003406.108505.37900HepG2ZNF622
PFKMENSG00000152556.11733.834401087.09890-0.567005.384503.66840K562ABCF1
PFKMENSG00000152556.112033.300301492.913100.445608.410107.49470K562AGGF1
PFKMENSG00000152556.11713.723701670.93810-1.2272023.4406021.91830K562AQR
PFKMENSG00000152556.11487.27090674.29310-0.468702.428901.45410K562CCAR1
PFKMENSG00000152556.111333.059501784.04670-0.420404.691503.12400K562CCDC124
PFKMENSG00000152556.111941.781202451.99300-0.336603.764202.62020K562CELF1
PFKMENSG00000152556.111553.452901227.691100.339404.275303.48980K562DDX47
PFKMENSG00000152556.11540.00860754.80050-0.483103.045201.64700K562DHX30
PFKMENSG00000152556.11459.37730768.64050-0.742604.088901.91050K562DNAJC2
PFKMENSG00000152556.11567.17150831.55600-0.552004.770603.55740K562EFTUD2
PFKMENSG00000152556.11907.626301139.69910-0.328503.369402.58810K562EIF2S2
PFKMENSG00000152556.11435.65810685.90090-0.654803.484002.34420K562EIF3A
PFKMENSG00000152556.11617.29060868.33660-0.492304.444303.40320K562EIF4A3
PFKMENSG00000152556.111164.036701994.15500-0.7766018.8813016.57300K562EIF4G2
PFKMENSG00000152556.11451.69860782.59500-0.792906.286105.12210K562G3BP2
PFKMENSG00000152556.11665.165301015.63500-0.610603.687502.37870K562GLRX3
PFKMENSG00000152556.11383.49550508.98080-0.408402.200101.49020K562GPKOW
PFKMENSG00000152556.11566.77960826.21510-0.543704.970004.19280K562HNRNPC
PFKMENSG00000152556.11975.183401310.16530-0.426005.062103.84080K562HNRNPU
PFKMENSG00000152556.11418.72570704.41820-0.750405.134503.11460K562ILF3
PFKMENSG00000152556.11420.42360680.92980-0.695705.015703.02740K562KHDRBS1
PFKMENSG00000152556.11860.416401137.78500-0.403102.222501.46480K562MAGOH
PFKMENSG00000152556.11797.425201135.35570-0.509702.862101.92270K562MATR3
PFKMENSG00000152556.111362.870702125.56580-0.641208.458606.53360K562MSI2
PFKMENSG00000152556.111190.36220867.132700.457004.847703.21680K562NCBP2
PFKMENSG00000152556.111619.032102181.28140-0.430004.321502.43480K562NOL12
PFKMENSG00000152556.11498.62020809.20290-0.698606.631705.46900K562PRPF8
PFKMENSG00000152556.111433.793102175.76960-0.601707.709706.34210K562PUF60
PFKMENSG00000152556.111932.647202314.30080-0.260002.463501.46130K562PUM1
PFKMENSG00000152556.111855.865202267.52750-0.289003.330002.27550K562PUM2
PFKMENSG00000152556.111892.172701540.464400.296602.366701.85590K562PUS1
PFKMENSG00000152556.111736.446101501.071300.210001.916101.40690K562RBM15
PFKMENSG00000152556.11650.287001059.59680-0.704405.382904.16400K562RBM22
PFKMENSG00000152556.11949.18080675.759200.490104.772403.46800K562RCC2
PFKMENSG00000152556.11716.097301032.20650-0.527503.883701.70780K562SAFB2
PFKMENSG00000152556.11318.61130484.04930-0.603403.518102.41870K562SF3B1
PFKMENSG00000152556.11507.88880742.79280-0.548403.695902.21400K562SLBP
PFKMENSG00000152556.11772.517501199.55330-0.634903.789602.71310K562SRPK2
PFKMENSG00000152556.111407.202501083.837100.376602.910102.18800K562SRSF1
PFKMENSG00000152556.11783.191401096.72120-0.485802.958302.22680K562TARDBP
PFKMENSG00000152556.11465.70160783.71090-0.750908.607507.17580K562U2AF2
PFKMENSG00000152556.11747.588501127.67200-0.593005.220303.56780K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PFKM is not available on ENCORE database.





13 RBPs can affect the splicing of PFKM :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPFKMENSG00000152556.11chr12+485356964853584948535522485356104853656448536729-0.195000.000170.00920excludedK562PRPF8
SEPFKMENSG00000152556.11chr12+485290734852916648528725485288214853150348531629-0.161000.000010.01602excludedK562UTP3
SEPFKMENSG00000152556.11chr12+485290734852916648528725485288214853150348531629-0.153000.000000.00377excludedK562PUM1
SEPFKMENSG00000152556.11chr12+485290734852916648528725485288214853150348531629-0.344000.000000.00000excludedK562PCBP1
SEPFKMENSG00000152556.11chr12+485356964853584948535522485356104853656448536729-0.064000.003130.03173excludedK562AQR
SEPFKMENSG00000152556.11chr12+485356964853584948535522485356104853656448536729-0.308000.000000.00006excludedK562EFTUD2
SEPFKMENSG00000152556.11chr12+485290734852916648528725485288214853150348531629-0.145000.000010.00873excludedK562PPIL4
SEPFKMENSG00000152556.11chr12+485350934853516448534504485346544853552248535610-0.139000.003950.06010excludedK562U2AF2
SEPFKMENSG00000152556.11chr12+4852907348529166485287254852882148531503485316290.107000.001260.04791includedK562PTBP1
A5SSPFKMENSG00000152556.11chr12+485287254852916648528725485288214853150348531629-0.421000.000000.00024shorterK562PCBP1
A5SSPFKMENSG00000152556.11chr12+4853306748533287485330674853313248533631485336950.123000.000670.01314longerK562AQR
A5SSPFKMENSG00000152556.11chr12+485355224853584948535522485356104853656448536729-0.138000.003580.05483shorterK562AQR
A5SSPFKMENSG00000152556.11chr12+485287254852916648528725485288214853150348531629-0.169000.000010.00902shorterK562PPIL4
A5SSPFKMENSG00000152556.11chr12+485355224853584948535522485356104853656448536729-0.292000.000980.07851shorterK562PRPF8
A5SSPFKMENSG00000152556.11chr12+485330674853328748533067485331324853363148533695-0.148000.000840.06703shorterK562FXR1
A5SSPFKMENSG00000152556.11chr12+485355224853584948535522485356104853656448536729-0.442000.000010.00176shorterK562EFTUD2
A5SSPFKMENSG00000152556.11chr12+485287254852916648528725485288214853150348531629-0.196000.000000.00610shorterK562PUM1
RIPFKMENSG00000152556.11chr12+4853552248535849485355224853561048535696485358490.083000.000870.01608includedK562SF3B4
RIPFKMENSG00000152556.11chr12+485287254852916648528725485288214852907348529166-0.127000.000150.00556excludedK562SRSF1
RIPFKMENSG00000152556.11chr12+485287254852916648528725485288214852907348529166-0.115000.000290.02615excludedK562KHSRP
RIPFKMENSG00000152556.11chr12+4852872548529166485287254852882148529073485291660.277000.001200.01836includedK562U2AF2
RIPFKMENSG00000152556.11chr12+4853552248535849485355224853561048535696485358490.092000.000980.01544includedK562U2AF2
RIPFKMENSG00000152556.11chr12+4852872548529166485287254852882148529073485291660.574000.004490.03247includedHepG2SF3B4
RIPFKMENSG00000152556.11chr12+4852872548529166485287254852882148529073485291660.247000.000010.00007includedK562AQR
RIPFKMENSG00000152556.11chr12+485287254852916648528725485288214852907348529166-0.131000.000240.00698excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PFKM is not avaliable on ENCORE database.