OSBPL2

General Information

Gene Name       : OSBPL2
Gene ID             : ENSG00000130703.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: OSBPL2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878OSBPL2ENSG00000130703.1610.3510.2010.27ENCSR000AEF
HepG2OSBPL2ENSG00000130703.1621.2826.1023.69ENCSR985KAT
K562OSBPL2ENSG00000130703.1614.3714.1914.28ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for OSBPL2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • OSBPL2 RNA is bound by 31 proteins.  







eCLIP assay for OSBPL2 is not avaliable on ENCORE database.





31 proteins are bound to OSBPL2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr206085435760854439+3'-UTR,CDS,intron-Proximal4.8075519.17857HepG2PRPF8
chr206085439560854437+3'-UTR,CDS,intron-Proximal4.038674.89208K562AQR
chr206086960860869672+3'-UTR3.217863.44847HepG2PABPN1
chr206083111260831221+5'-UTR,intron-Proximal4.233926.71767K562DDX3X
chr206083111260831126+5'-UTR,intron-Proximal3.135404.62864K562ZNF622
chr206083867760838751+5'-UTR,CDS,intron-Proximal4.5511213.64823HepG2PPIG
chr206083125660831278+5'-UTR,CDS,intron-Proximal3.248653.02345K562ZNF622
chr206083870560838747+5'-UTR,CDS3.540584.74268K562UCHL5
chr206081361360813653+5'-UTR3.434833.43213K562UCHL5
chr206081359060813660+5'-UTR,intron-Proximal3.139466.18886HepG2NCBP2
chr206081361660813697+5'-UTR,intron-Proximal4.0454624.54863HepG2PRPF8
chr206081361660813697+5'-UTR,intron-Proximal4.752914.53454K562PRPF8
chr206083118660831246+5'-UTR,CDS3.149686.52802K562ZNF622
chr206083110860831156+5'-UTR,intron-Proximal4.375945.12808HepG2NCBP2
chr206085621260856289+CDS,intron-Proximal3.431695.19487K562PRPF8
chr206086678060866852+CDS,intron-Proximal3.269657.16368HepG2PPIG
chr206086678660866838+CDS4.391104.72838K562UCHL5
chr206086677360866847+CDS3.611848.66838HepG2BCLAF1
chr206085682660856888+CDS,intron-Proximal4.366173.31283K562PRPF8
chr206085617160856203+CDS3.867413.38114HepG2GRWD1
chr206086884160868892+CDS4.877166.91190HepG2PPIG
chr206085611560856171+CDS3.059993.90804HepG2GRWD1
chr206085620860856271+CDS,intron-Proximal3.388378.89076K562BUD13
chr206084838460848432+CDS4.849945.86613HepG2PPIG
chr206085680760856871+CDS,intron-Proximal5.2523212.70303K562AQR
chr206085621660856261+CDS,intron-Proximal3.900253.98855HepG2SUPV3L1
chr206085621460856229+CDS,intron-Proximal4.4875513.47152HepG2PRPF8
chr206085621760856254+CDS,intron-Proximal6.1132634.61864K562AQR
chr206084724460847288+CDS4.220583.87995K562UCHL5
chr206086676160866804+CDS3.098685.59833HepG2GRWD1
chr206086435060864386+CDS,intron-Distal4.366874.69889HepG2GRWD1
chr206085610460856144+CDS,intron-Proximal3.309435.85200K562BUD13
chr206085620760856263+CDS,intron-Proximal3.309345.95628HepG2AQR
chr206085419260854284+CDS,intron-Proximal3.5340410.12893HepG2U2AF2
chr206086676460866784+CDS4.031833.11168K562ZNF622
chr206084728260847356+CDS,intron-Proximal3.6875119.31948HepG2PRPF8
chr206085916960859257+CDS,intron-Proximal4.419608.98365HepG2PPIG
chr206085914060859211+CDS3.887936.46787HepG2GRWD1
chr206086176060861804+CDS,intron-Proximal5.233479.27403HepG2PRPF8
chr206084731260847335+CDS,intron-Proximal3.997436.80869K562AQR
chr206086080260860864+intron-Distal3.463936.27327K562RBM15
chr206085922760859348+intron-Distal,intron-Proximal4.1248411.78536HepG2RBM22
chr206086363460863706+intron-Distal3.675635.32871HepG2CSTF2T
chr206085630260856360+intron-Distal,intron-Proximal3.021809.75793K562BUD13
chr206085974660859791+intron-Distal3.033613.40206HepG2HNRNPC
chr206085304060853117+intron-Distal3.598484.61131K562EIF4G2
chr206083379660833848+intron-Distal5.4869910.99895HepG2HNRNPM
chr206085874360858846+intron-Distal3.199813.59783HepG2HNRNPK
chr206085395960854012+intron-Distal5.338928.06678K562TARDBP
chr206085371660853756+intron-Distal4.824977.26804K562TARDBP
chr206085628960856367+intron-Distal,intron-Proximal3.091954.23238K562PRPF8
chr206081375660813841+intron-Distal3.681737.81658HepG2XRN2
chr206085364860853707+intron-Distal5.4814112.64183K562TARDBP
chr206085302160853119+intron-Distal4.161693.02711K562EWSR1
chr206081719760817285+intron-Distal3.669617.58130HepG2HNRNPM
chr206085384760853954+intron-Distal5.4895819.06771K562TARDBP
chr206085402860854099+intron-Distal4.645997.62986K562EIF4G2
chr206082152460821603+intron-Distal3.325523.53873HepG2HNRNPM
chr206085626260856344+intron-Distal,intron-Proximal4.8663423.10694K562AQR
chr206081400660814060+intron-Distal3.373403.24283HepG2NKRF
chr206085256860852620+intron-Distal3.613373.39857HepG2HNRNPM
chr206086364160863692+intron-Distal3.859703.01994HepG2GTF2F1
chr206081760860817691+intron-Distal3.097413.33745HepG2HNRNPM
chr206082501160825083+intron-Distal4.274275.53837HepG2XPO5
chr206085409960854135+intron-Distal,intron-Proximal3.364733.12825K562EIF4G2
chr206086310960863249+intron-Distal4.440908.40329HepG2PRPF4
chr206086038860860433+intron-Distal3.967593.05875K562RBM15
chr206083201660832074+intron-Distal3.468938.02804HepG2HNRNPM
chr206084875860848809+intron-Distal4.389614.13641K562TARDBP
chr206085627860856355+intron-Distal,intron-Proximal3.506097.53508HepG2BUD13
chr206083366660833741+intron-Distal4.065145.28337HepG2HNRNPM
chr206084604260846170+intron-Distal3.302084.41421K562PTBP1
chr206086364160863693+intron-Distal5.048856.83853HepG2PRPF4
chr206082763560827690+intron-Distal3.606374.86210HepG2HNRNPM
chr206085384960853937+intron-Distal5.864739.37109K562EIF4G2
chr206084804260848158+intron-Distal4.0722510.09217K562EIF4G2
chr206083222360832292+intron-Distal3.643373.68481HepG2HNRNPM
chr206085337160853444+intron-Distal5.529669.16624K562TARDBP
chr206081726060817303+intron-Distal4.080769.77119HepG2XPO5
chr206084801860848114+intron-Distal6.2893521.08007K562TARDBP
chr206084608660846173+intron-Distal3.337514.39142HepG2PCBP2
chr206086055260860630+intron-Distal3.608544.88634K562RBM15
chr206085347060853526+intron-Distal4.7231211.87937K562TARDBP
chr206085678560856836+intron-Proximal5.684717.02785HepG2SF3A3
chr206084733560847361+intron-Proximal4.9252311.65116K562AQR
chr206086158160861635+intron-Proximal4.7426714.91772HepG2SF3B4
chr206085625460856262+intron-Proximal6.5424430.96851K562AQR
chr206085606260856110+intron-Proximal5.167404.90235K562SF3B4
chr206084830360848355+intron-Proximal4.340284.50924HepG2SF3B4
chr206085627160856302+intron-Proximal3.796204.97821K562BUD13
chr206083875660838785+intron-Proximal3.959985.61068HepG2PRPF8
chr206085622960856268+intron-Proximal4.4716820.98117HepG2PRPF8
chr206083874760838756+intron-Proximal3.900195.31213HepG2PRPF8
chr206084736860847408+intron-Proximal3.932625.26367K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for OSBPL2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for OSBPL2 is not available on ENCORE database.

  • 53 RBPs can affect the levels of OSBPL2.  








The Knockdown/knockout RNA-Seq assay for OSBPL2 is not available on ENCORE database.





53 RBPs can affect the gene expression of OSBPL2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
OSBPL2ENSG00000130703.11906.326001321.73850-0.5443010.192209.17820HepG2ACO1
OSBPL2ENSG00000130703.11618.50370963.53730-0.639606.289804.86690HepG2ADAR
OSBPL2ENSG00000130703.111175.54000860.451100.450103.009302.06970HepG2BCLAF1
OSBPL2ENSG00000130703.111521.062301196.058400.346703.549202.69200HepG2CALR
OSBPL2ENSG00000130703.111212.79580988.115200.295502.813801.78710HepG2YBX3
OSBPL2ENSG00000130703.111854.720101605.017700.208502.583501.86260HepG2DAZAP1
OSBPL2ENSG00000130703.111262.73180969.269200.381503.097302.38290HepG2DDX21
OSBPL2ENSG00000130703.112394.659701555.398300.622406.829305.88880HepG2DDX3X
OSBPL2ENSG00000130703.111807.738201336.187800.436003.107102.45600HepG2DDX6
OSBPL2ENSG00000130703.111114.94230961.712500.213202.070801.49120HepG2DNAJC2
OSBPL2ENSG00000130703.112049.220001284.441800.673807.730606.77640HepG2EIF2S1
OSBPL2ENSG00000130703.111070.304901419.42630-0.407302.630002.00600HepG2EIF4A3
OSBPL2ENSG00000130703.112492.891101975.384300.335604.793204.04060HepG2ETF1
OSBPL2ENSG00000130703.111231.09840923.415800.414803.692402.39950HepG2FASTKD2
OSBPL2ENSG00000130703.111414.458001075.656800.394903.606302.71520HepG2FUBP3
OSBPL2ENSG00000130703.112341.140701604.053800.545405.243604.38080HepG2GPKOW
OSBPL2ENSG00000130703.111870.316501345.410900.475104.738303.84560HepG2HNRNPK
OSBPL2ENSG00000130703.111324.048101105.559600.260103.158302.37970HepG2ILF2
OSBPL2ENSG00000130703.111011.235301208.21030-0.256802.913101.87200HepG2KIF1C
OSBPL2ENSG00000130703.112596.448801934.054300.424802.700101.47070HepG2KRR1
OSBPL2ENSG00000130703.111709.023301410.075600.277302.297601.55790HepG2MSI2
OSBPL2ENSG00000130703.111952.099901474.668700.404503.024202.36380HepG2NCBP2
OSBPL2ENSG00000130703.111747.262401357.290200.364303.071602.28440HepG2NSUN2
OSBPL2ENSG00000130703.111309.235801071.288500.289303.081002.19050HepG2PARN
OSBPL2ENSG00000130703.111400.702701174.462800.254002.560601.81390HepG2PRPF4
OSBPL2ENSG00000130703.111543.933601319.536400.226502.244601.74190HepG2PTBP1
OSBPL2ENSG00000130703.112308.234001611.577300.518208.037506.92030HepG2PUM2
OSBPL2ENSG00000130703.111859.408901428.951700.379804.728703.94420HepG2QKI
OSBPL2ENSG00000130703.112817.448301651.023900.7709020.0841018.94950HepG2RBM22
OSBPL2ENSG00000130703.111322.385401044.714600.339902.415701.66360HepG2RPS2
OSBPL2ENSG00000130703.111444.52430963.847100.583607.288806.31440HepG2SAFB2
OSBPL2ENSG00000130703.112252.748101767.449500.349901.863201.30720HepG2SF3A3
OSBPL2ENSG00000130703.111900.419401515.190500.326702.619901.93300HepG2SF3B1
OSBPL2ENSG00000130703.111791.172201373.690900.382705.867705.06060HepG2SF3B4
OSBPL2ENSG00000130703.111480.793301077.755000.458202.782201.82250HepG2SMNDC1
OSBPL2ENSG00000130703.112244.062801685.905600.412502.174101.48510HepG2SNRNP70
OSBPL2ENSG00000130703.112795.953001864.714400.5843014.9883014.06910HepG2SRFBP1
OSBPL2ENSG00000130703.111773.151001520.300000.221902.748002.05390HepG2SRSF7
OSBPL2ENSG00000130703.111635.241301166.581700.487109.481608.56670HepG2SRSF9
OSBPL2ENSG00000130703.111596.991401176.464500.440804.980603.73880HepG2SUPT6H
OSBPL2ENSG00000130703.111301.59060969.239500.425302.766002.08920HepG2SUPV3L1
OSBPL2ENSG00000130703.111685.072401184.240800.508705.033003.91610HepG2TIA1
OSBPL2ENSG00000130703.111353.658701061.093200.351203.895503.24970HepG2TRIM56
OSBPL2ENSG00000130703.112407.184001490.321900.691609.575908.39190HepG2U2AF1
OSBPL2ENSG00000130703.111823.024401567.458000.217802.434701.77250HepG2UPF1
OSBPL2ENSG00000130703.111127.255401513.31830-0.424906.591405.73360HepG2UTP3
OSBPL2ENSG00000130703.112244.506401723.903000.380608.275107.46040HepG2ZNF622
OSBPL2ENSG00000130703.11990.818201347.23680-0.443304.978003.23760K562APOBEC3C
OSBPL2ENSG00000130703.11481.12180610.72330-0.344102.364201.62560K562EIF3G
OSBPL2ENSG00000130703.11671.79540990.71900-0.560507.401106.47540K562FXR1
OSBPL2ENSG00000130703.111042.30750786.695200.405803.279702.41670K562GPKOW
OSBPL2ENSG00000130703.11676.19260967.59480-0.517005.592704.67770K562PTBP1
OSBPL2ENSG00000130703.11545.14940722.72940-0.406802.913801.80350K562SAFB
OSBPL2ENSG00000130703.111673.600301076.211000.636902.401401.31400K562SF1
OSBPL2ENSG00000130703.111066.58590852.623000.322903.198401.93620K562SRSF7
OSBPL2ENSG00000130703.11531.72010813.58810-0.613606.902605.59220K562SYNCRIP
OSBPL2ENSG00000130703.111538.510201224.794100.328903.299602.51890K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for OSBPL2 is not available on ENCORE database.





10 RBPs can affect the splicing of OSBPL2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEOSBPL2ENSG00000130703.11chr20+608483646084846260847180608473156085421260854395-0.119000.000000.00000excludedK562PUS1
SEOSBPL2ENSG00000130703.11chr20+608550646085517860854223608544056085611360856221-0.150000.001020.03123excludedHepG2SF3A3
SEOSBPL2ENSG00000130703.11chr20+608396846083977460838671608387476084718060847315-0.077000.000900.07699excludedHepG2SUPV3L1
SEOSBPL2ENSG00000130703.11chr20+6083968460839774608386716083874760847180608473150.114000.000450.00976includedK562HNRNPC
A5SSOSBPL2ENSG00000130703.11chr20+6085421260854405608542126085439560856113608562210.079000.000390.01753longerK562PUS1
A5SSOSBPL2ENSG00000130703.11chr20+6085421260854405608542126085439560856113608562210.088000.000930.01755longerK562AQR
MXEOSBPL2ENSG00000130703.11chr20+6083111260831277608350366083518160813579608136536083867160838747-0.136000.000250.007732includedHepG2FTO
MXEOSBPL2ENSG00000130703.11chr20+6083111260831277608350366083518160813579608136536083867160838747-0.186000.000340.052922includedHepG2RBM5
MXEOSBPL2ENSG00000130703.11chr20+6086163860861767608642626086438660859101608592256086675860866849-0.248000.000240.008692includedK562TARDBP
MXEOSBPL2ENSG00000130703.11chr20+60831112608312776083503660835181608135796081365360838671608387470.155000.000320.016341includedHepG2RBFOX2
MXEOSBPL2ENSG00000130703.11chr20+6083111260831277608350366083518160813579608136536083867160838747-0.130000.005830.094872includedK562PPIL4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for OSBPL2 is not avaliable on ENCORE database.