MRPL22

General Information

Gene Name       : MRPL22
Gene ID             : ENSG00000082515.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MRPL22)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MRPL22ENSG00000082515.1746.0342.0844.05ENCSR000AEF
HepG2MRPL22ENSG00000082515.1757.2477.7467.49ENCSR985KAT
K562MRPL22ENSG00000082515.1748.3868.3058.34ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MRPL22 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MRPL22 RNA is bound by 9 proteins.  







eCLIP assay for MRPL22 is not avaliable on ENCORE database.





9 proteins are bound to MRPL22 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5154346338154346403+3'-UTR,CDS4.7460213.15731K562RBM15
chr5154335869154335935+3'-UTR,CDS,intron-Proximal4.633846.11702K562SF3B4
chr5154346402154346492+3'-UTR,CDS3.492134.63830HepG2LARP4
chr5154346425154346477+3'-UTR,CDS6.2038375.76488K562PUM2
chr5154346477154346511+3'-UTR7.9492453.15509K562PUM2
chr5154346184154346286+3'-UTR,CDS,intron-Proximal4.472875.63851K562SF3B4
chr5154346226154346296+3'-UTR,CDS,intron-Proximal3.786894.79983HepG2U2AF2
chr5154339483154339633+3'-UTR,CDS,intron-Proximal5.107254.90235K562SF3B4
chr5154336699154336773+3'-UTR,CDS,intron-Proximal3.498593.27569HepG2BCLAF1
chr5154320771154320815+5'-UTR,CDS,intron-Proximal3.687974.12910K562DROSHA
chr5154320791154320851+5'-UTR,CDS,intron-Proximal4.431319.10443HepG2PRPF8
chr5154320975154321111+intron-Distal4.1972616.85722K562KHSRP
chr5154330244154330289+intron-Distal,intron-Proximal3.437023.68839K562KHSRP
chr5154328445154328575+intron-Distal3.164785.83938K562KHSRP
chr5154330105154330244+intron-Distal4.376746.83037K562KHSRP
chr5154322266154322361+intron-Distal3.803115.56048K562KHSRP
chr5154320968154321087+intron-Distal3.756006.09419HepG2KHSRP
chr5154339737154339857+intron-Distal3.334714.13575K562KHSRP
chr5154322361154322426+intron-Distal3.152834.08064K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MRPL22 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MRPL22 is not available on ENCORE database.

  • 77 RBPs can affect the levels of MRPL22.  








The Knockdown/knockout RNA-Seq assay for MRPL22 is not available on ENCORE database.





77 RBPs can affect the gene expression of MRPL22 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MRPL22ENSG00000082515.12600.29550905.72770-0.593404.172003.53730HepG2AKAP1
MRPL22ENSG00000082515.12542.42950749.42100-0.466303.050202.22680HepG2ASCC1
MRPL22ENSG00000082515.12370.74040508.52830-0.455902.092101.30590HepG2BCLAF1
MRPL22ENSG00000082515.12478.86720685.71790-0.518004.004403.29870HepG2BOP1
MRPL22ENSG00000082515.12392.83200629.51770-0.680305.601804.65550HepG2CPSF6
MRPL22ENSG00000082515.12622.86150495.109300.331102.421101.47160HepG2YBX3
MRPL22ENSG00000082515.12693.09520836.52390-0.271402.143901.56710HepG2CELF1
MRPL22ENSG00000082515.12353.70420481.85640-0.446103.957603.20510HepG2DNAJC2
MRPL22ENSG00000082515.12409.73790716.49130-0.806207.421606.48570HepG2EIF2S1
MRPL22ENSG00000082515.12484.33990770.91880-0.670604.221303.38070HepG2EIF4B
MRPL22ENSG00000082515.12715.62980887.41900-0.310402.719002.12240HepG2ETF1
MRPL22ENSG00000082515.12603.28380798.86460-0.405102.539701.87580HepG2FXR1
MRPL22ENSG00000082515.12433.09290741.09220-0.775006.876805.84700HepG2G3BP1
MRPL22ENSG00000082515.12478.52830713.58370-0.576504.010803.25270HepG2GPKOW
MRPL22ENSG00000082515.12356.52580490.84100-0.461202.873602.21510HepG2HNRNPA1
MRPL22ENSG00000082515.12240.71760545.95860-1.1815013.4697012.04730HepG2HNRNPC
MRPL22ENSG00000082515.12539.44370691.59910-0.358502.885902.15530HepG2HNRNPF
MRPL22ENSG00000082515.12592.28140750.35720-0.341301.970201.37390HepG2HNRNPK
MRPL22ENSG00000082515.12684.03230819.39990-0.260502.282201.66200HepG2HNRNPL
MRPL22ENSG00000082515.12456.61820680.98820-0.576604.317603.54650HepG2HNRNPLL
MRPL22ENSG00000082515.12499.27630681.03190-0.447903.478102.67400HepG2IGF2BP1
MRPL22ENSG00000082515.12321.10460753.31400-1.2302015.7973014.34370HepG2IGF2BP2
MRPL22ENSG00000082515.12560.20600822.56160-0.554203.998703.24210HepG2NCBP2
MRPL22ENSG00000082515.12700.74560891.95200-0.348103.029002.23120HepG2NOL12
MRPL22ENSG00000082515.12461.61400732.57720-0.666305.512604.50510HepG2PABPC4
MRPL22ENSG00000082515.12544.78090700.22780-0.362103.078302.44370HepG2PCBP1
MRPL22ENSG00000082515.12461.29130712.53170-0.627307.533806.71970HepG2PTBP1
MRPL22ENSG00000082515.12651.90610851.43420-0.385202.954102.34160HepG2PUF60
MRPL22ENSG00000082515.12641.52240903.82080-0.494507.257906.39200HepG2PUM1
MRPL22ENSG00000082515.12598.41890903.16940-0.593806.931105.88740HepG2PUM2
MRPL22ENSG00000082515.12406.01930527.24740-0.376902.991902.35780HepG2PUS1
MRPL22ENSG00000082515.12534.89640771.63880-0.528705.160704.34660HepG2QKI
MRPL22ENSG00000082515.12500.00400700.33100-0.486103.915703.12410HepG2RBM25
MRPL22ENSG00000082515.12534.19050792.95970-0.569906.508105.73720HepG2NELFE
MRPL22ENSG00000082515.12489.53950738.56990-0.593306.955606.04310HepG2RECQL
MRPL22ENSG00000082515.12287.58000574.95190-0.9995010.226408.77310HepG2RPS2
MRPL22ENSG00000082515.12874.06120568.443900.620603.433102.67930HepG2SF3A3
MRPL22ENSG00000082515.12559.21520741.79490-0.407603.655802.98960HepG2SF3B4
MRPL22ENSG00000082515.12590.72960816.36350-0.466705.845804.88730HepG2SLBP
MRPL22ENSG00000082515.12523.62520749.98160-0.518302.542001.79350HepG2SNRNP70
MRPL22ENSG00000082515.12517.12590840.65020-0.7010010.770809.64490HepG2SRSF5
MRPL22ENSG00000082515.12465.17810679.45880-0.546605.923004.96720HepG2SRSF7
MRPL22ENSG00000082515.12488.00880629.94170-0.368303.158002.57630HepG2SRSF9
MRPL22ENSG00000082515.12626.19990956.06550-0.6105010.074609.01160HepG2SUCLG1
MRPL22ENSG00000082515.12318.00940572.78500-0.848906.007505.06840HepG2SUPV3L1
MRPL22ENSG00000082515.12528.77460696.01090-0.396503.275402.67240HepG2TAF15
MRPL22ENSG00000082515.12416.78240663.81550-0.671505.888604.88870HepG2TARDBP
MRPL22ENSG00000082515.12344.56170527.03670-0.613105.372304.72180HepG2TIAL1
MRPL22ENSG00000082515.12416.05820531.70250-0.353802.762802.19890HepG2TRIM56
MRPL22ENSG00000082515.12503.89080831.79200-0.723108.536806.85890HepG2TUFM
MRPL22ENSG00000082515.12614.73060880.42350-0.518203.364102.44210HepG2UBE2L3
MRPL22ENSG00000082515.12594.37710486.710300.288202.078201.54450HepG2UTP3
MRPL22ENSG00000082515.12671.01350554.438300.275202.262401.75270HepG2ZNF622
MRPL22ENSG00000082515.121064.274401350.09060-0.343202.572401.40100K562ABCF1
MRPL22ENSG00000082515.121290.84910893.918300.530008.678307.74760K562AGGF1
MRPL22ENSG00000082515.121270.66230930.168500.449904.357103.53090K562AKAP8L
MRPL22ENSG00000082515.121935.660601497.744600.369902.486601.92390K562AQR
MRPL22ENSG00000082515.121274.09150975.981900.384404.479203.28810K562ATP5C1
MRPL22ENSG00000082515.12615.22440814.92220-0.405504.199603.00230K562BCLAF1
MRPL22ENSG00000082515.12652.22990940.38280-0.527904.031102.25780K562BUD13
MRPL22ENSG00000082515.12992.785401204.17210-0.278502.611901.53800K562CPEB4
MRPL22ENSG00000082515.121355.998601000.890400.438005.950004.59660K562DKC1
MRPL22ENSG00000082515.12952.46170653.024800.544402.898502.28140K562FXR1
MRPL22ENSG00000082515.12211.70510818.40070-1.9508042.3546040.10940K562HNRNPC
MRPL22ENSG00000082515.121405.91270798.209400.816609.489307.54660K562HNRNPM
MRPL22ENSG00000082515.121695.122201315.765800.365402.931302.11320K562HSPD1
MRPL22ENSG00000082515.12649.43020918.69060-0.500403.322702.16260K562IGF2BP2
MRPL22ENSG00000082515.121462.18960987.120300.566706.442205.06200K562KIF1C
MRPL22ENSG00000082515.121199.82250944.934000.344402.410601.42990K562MAK16
MRPL22ENSG00000082515.12719.23420873.56080-0.280402.394101.64100K562MTPAP
MRPL22ENSG00000082515.121308.79140775.106400.755705.569804.16310K562NAA15
MRPL22ENSG00000082515.12793.81540970.60490-0.290103.099602.31330K562NSUN2
MRPL22ENSG00000082515.121331.38280846.110400.653902.852501.84290K562PABPN1
MRPL22ENSG00000082515.121068.01060647.472700.721908.021806.73900K562PRPF8
MRPL22ENSG00000082515.121507.076601832.03360-0.281703.086302.07490K562PUM2
MRPL22ENSG00000082515.121697.60550922.429200.8799013.3043012.15840K562PUS1
MRPL22ENSG00000082515.121431.90080898.803700.6718011.7518010.53890K562RBM15
MRPL22ENSG00000082515.121381.60610888.640100.636602.557201.39460K562SNRNP200
MRPL22ENSG00000082515.121207.739001533.77800-0.344803.577701.86530K562SUCLG1
MRPL22ENSG00000082515.121040.05810853.622100.284902.182201.45230K562SYNCRIP
MRPL22ENSG00000082515.12724.31180897.84410-0.309902.239401.51010K562TIA1
MRPL22ENSG00000082515.12733.622901029.15290-0.488306.775605.70640K562UPF1
MRPL22ENSG00000082515.12985.485901296.82100-0.396103.025101.76350K562UTP3
MRPL22ENSG00000082515.12686.04370880.61370-0.360202.812401.92880K562WDR3
MRPL22ENSG00000082515.121302.847101687.33890-0.373103.460002.47650K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MRPL22 is not available on ENCORE database.





32 RBPs can affect the splicing of MRPL22 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543206541543208251543359301543359960.088000.000000.00004includedK562SRSF1
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320654154320825154335930154335996-0.113000.000030.00098excludedK562SF3B4
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207511543208251543359301543359960.097000.000060.00674includedHepG2RBM22
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543206541543208251543359301543359960.083000.000010.00324includedK562MATR3
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320654154320825154335930154335996-0.262000.000000.00000excludedHepG2U2AF1
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207761543208251543359301543359960.152000.000030.00754includedHepG2HNRNPM
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.099000.001060.08031excludedK562XRCC6
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207761543208251543359301543359960.145000.000840.06410includedHepG2TBRG4
SEMRPL22ENSG00000082515.12chr5+1543303621543305061543207761543208251543359301543359960.055000.005500.05723includedHepG2U2AF2
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207761543208251543359301543359960.085000.000130.01231includedHepG2AKAP1
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.127000.000000.00002excludedK562AQR
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207761543208251543359301543359960.131000.000000.01539includedHepG2SUB1
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320654154320825154335930154335996-0.169000.000030.00459excludedK562SUPV3L1
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320654154320825154335930154335996-0.193000.000000.00000excludedK562PUS1
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.120000.000180.04240excludedK562MTPAP
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207761543208251543359301543359960.248000.000000.00000includedHepG2SFPQ
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543206541543208251543359301543359960.139000.000000.00000includedHepG2MATR3
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.396000.000000.00000excludedK562U2AF1
SEMRPL22ENSG00000082515.12chr5+1543303621543304981543207761543208251543359301543359960.150000.000580.06480includedHepG2PCBP2
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.183000.000000.00002excludedHepG2HNRNPL
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.215000.000000.00000excludedK562HNRNPL
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207761543208251543359301543359960.168000.000160.09608includedHepG2PPIG
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543206541543208251543359301543359960.117000.000000.00011includedHepG2SRSF1
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.117000.000750.02449excludedHepG2SF3A3
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207761543208251543359301543359960.123000.000420.03488includedHepG2TIAL1
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.117000.000050.04311excludedK562TBRG4
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.117000.000020.00153excludedK562UTP18
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.074000.005070.07342excludedK562U2AF2
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.089000.002100.06634excludedK562HNRNPU
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320654154320825154335930154335996-0.105000.000080.00373excludedK562RBM15
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.074000.004820.09057excludedK562AGGF1
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543207761543208251543359301543359960.116000.000150.02369includedK562CPSF6
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.104000.000540.08767excludedHepG2DDX55
SEMRPL22ENSG00000082515.12chr5+1543303801543304981543206541543208251543359301543359960.168000.000060.02344includedHepG2EIF3D
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.131000.000020.00971excludedHepG2XRN2
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.085000.000500.02670excludedK562HNRNPK
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.111000.000450.08556excludedHepG2XRCC6
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.223000.000000.00002excludedHepG2HNRNPC
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.087000.000460.02202excludedK562PTBP1
SEMRPL22ENSG00000082515.12chr5+154330380154330498154320776154320825154335930154335996-0.404000.000000.00000excludedK562HNRNPC
A3SSMRPL22ENSG00000082515.12chr5+1543303621543304981543303801543304981543207761543208250.144000.000000.00000longerK562AQR
A3SSMRPL22ENSG00000082515.12chr5+1543303621543304981543303801543304981543207761543208250.062000.000320.01520longerHepG2U2AF1
RIMRPL22ENSG00000082515.12chr5+1543206611543208861543206611543206981543207761543208860.122000.000000.00000includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+1543207761543208251543303801543304981543206291543206981543359301543359960.120000.002420.061501includedK562XRN2
MXEMRPL22ENSG00000082515.12chr5+1543303351543304981543359301543359801543207761543208251543366941543367720.051000.005790.040681includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+1543303621543304981543359301543359961543207761543208251543366941543367720.076000.000000.000001includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+1543303621543304981543359301543361201543207761543208251543366941543367720.178000.000000.000001includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+1543303621543304981543358311543359961543207761543208251543366941543367720.112000.000000.000001includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+1543303621543304981543359301543359801543207761543208251543366941543367720.243000.000000.000001includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+154330380154330498154335930154335996154320776154320825154336694154336772-0.164000.000000.000002includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+154330380154330498154335930154336120154320776154320825154336694154336772-0.205000.000000.000002includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+154330380154330498154335831154335996154320776154320825154336694154336772-0.157000.000010.000142includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+154330380154330498154335930154335980154320776154320825154336694154336772-0.161000.000000.000002includedK562AQR
MXEMRPL22ENSG00000082515.12chr5+154320776154320825154339507154339609154320661154320698154346245154348971-0.095000.002300.018732includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MRPL22 is not avaliable on ENCORE database.