METTL21A

General Information

Gene Name       : METTL21A
Gene ID             : ENSG00000144401.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: METTL21A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878METTL21AENSG00000144401.1415.1417.7216.43ENCSR000AEF
HepG2METTL21AENSG00000144401.1435.3956.9246.16ENCSR985KAT
K562METTL21AENSG00000144401.1422.1923.3122.75ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for METTL21A is not avaliable on ENCORE database.



Proteins bound to RNA
  • METTL21A RNA is bound by 11 proteins.  







eCLIP assay for METTL21A is not avaliable on ENCORE database.





11 proteins are bound to METTL21A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2208477749208477853-3'-UTR,CDS,intron-Distal,intron-Proximal3.668589.11737K562PUM2
chr2208474051208474125-3'-UTR,intron-Distal3.529483.51804HepG2HNRNPL
chr2208489965208490005-5'-UTR,intron-Distal,intron-Proximal6.247978.23278HepG2DDX3X
chr2208489042208489132-5'-UTR,CDS,intron-Distal,intron-Proximal3.8198014.95094HepG2DDX3X
chr2208489051208489129-5'-UTR,CDS,intron-Distal,intron-Proximal4.406937.55366K562DDX3X
chr2208489785208489887-5'-UTR,intron-Distal,intron-Proximal4.0505521.91339HepG2DDX3X
chr2208486528208486628-CDS,intron-Distal,intron-Proximal4.342257.72002HepG2GRSF1
chr2208469711208469799-intron-Distal4.791265.30852HepG2HNRNPL
chr2208471702208471805-intron-Distal4.443934.68586HepG2HNRNPL
chr2208469374208469426-intron-Distal3.004533.54017HepG2HLTF
chr2208482172208482267-intron-Distal4.317534.43431HepG2RBFOX2
chr2208473744208473839-intron-Distal,intron-Proximal4.129674.86595HepG2CSTF2
chr2208486262208486346-intron-Distal4.441404.51355HepG2PTBP1
chr2208482401208482459-intron-Distal3.413463.10961HepG2MATR3
chr2208482560208482624-intron-Distal3.9871111.53546HepG2PCBP2
chr2208486404208486478-intron-Distal,intron-Proximal3.890073.31824HepG2TIAL1
chr2208482498208482562-intron-Distal3.418305.93274HepG2PTBP1
chr2208482439208482547-intron-Distal4.707066.10679HepG2RBFOX2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for METTL21A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for METTL21A is not available on ENCORE database.

  • 63 RBPs can affect the levels of METTL21A.  








The Knockdown/knockout RNA-Seq assay for METTL21A is not available on ENCORE database.





63 RBPs can affect the gene expression of METTL21A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
METTL21AENSG00000144401.10443.99040995.17670-1.1644016.3530014.62050HepG2ASCC1
METTL21AENSG00000144401.10655.68220945.47830-0.528004.192703.25270HepG2CIRBP
METTL21AENSG00000144401.10549.95990766.31720-0.478605.200404.36950HepG2CELF1
METTL21AENSG00000144401.10319.62030453.21610-0.503803.168502.44600HepG2DDX21
METTL21AENSG00000144401.10807.207501152.17060-0.513304.046503.30130HepG2DDX3X
METTL21AENSG00000144401.10356.77270494.36890-0.470603.225401.76340HepG2DDX52
METTL21AENSG00000144401.10721.06630989.61200-0.456702.919202.28670HepG2DDX6
METTL21AENSG00000144401.10371.11490589.84410-0.668504.926003.72730HepG2EEF2
METTL21AENSG00000144401.10534.06000951.46350-0.833108.785207.76790HepG2EIF2S1
METTL21AENSG00000144401.10675.677101051.53960-0.638105.275804.39350HepG2EIF4A3
METTL21AENSG00000144401.10677.093301023.70560-0.596403.779402.98150HepG2EIF4B
METTL21AENSG00000144401.10398.77090653.78490-0.713305.227004.19710HepG2FIP1L1
METTL21AENSG00000144401.10410.21120649.77490-0.663605.912904.78440HepG2FUBP3
METTL21AENSG00000144401.10614.072301060.77580-0.788608.459807.30480HepG2FXR1
METTL21AENSG00000144401.10510.98820984.12170-0.9455010.791609.52160HepG2G3BP1
METTL21AENSG00000144401.10310.84040426.32980-0.455802.458101.61880HepG2GEMIN5
METTL21AENSG00000144401.10295.08760529.21730-0.842706.428204.85300HepG2GNB2L1
METTL21AENSG00000144401.10347.28770524.48370-0.594803.713702.98140HepG2GPKOW
METTL21AENSG00000144401.10294.62070588.93170-0.999208.811606.19520HepG2HNRNPAB
METTL21AENSG00000144401.10638.31560750.67930-0.233901.999201.41460HepG2HNRNPL
METTL21AENSG00000144401.10332.22740451.02850-0.441002.799801.84350HepG2HNRNPM
METTL21AENSG00000144401.10514.665901000.37260-0.9588011.8903010.59800HepG2IGF2BP2
METTL21AENSG00000144401.10579.387901006.13960-0.796206.650205.02100HepG2KHSRP
METTL21AENSG00000144401.10381.12120521.47370-0.452303.137302.05310HepG2KIF1C
METTL21AENSG00000144401.10631.395001061.14530-0.749007.589306.51760HepG2MAGOH
METTL21AENSG00000144401.10725.087301067.11430-0.557504.153303.39540HepG2MATR3
METTL21AENSG00000144401.10316.94760501.13140-0.660902.560701.54690HepG2METAP2
METTL21AENSG00000144401.10413.17570529.04340-0.356602.160201.44120HepG2MSI2
METTL21AENSG00000144401.10679.341201092.27510-0.685106.364805.42000HepG2NCBP2
METTL21AENSG00000144401.10705.26850443.838300.668005.700504.64750HepG2NSUN2
METTL21AENSG00000144401.10303.41200972.85370-1.6809029.9109027.62730HepG2PABPC4
METTL21AENSG00000144401.10640.77380930.42600-0.538107.491906.57150HepG2PCBP1
METTL21AENSG00000144401.10465.97490946.70920-1.0227021.0355019.79760HepG2PTBP1
METTL21AENSG00000144401.10637.56160780.00100-0.290901.874201.37010HepG2PUF60
METTL21AENSG00000144401.10964.09640827.979400.219501.834001.32980HepG2PUM1
METTL21AENSG00000144401.10563.06080827.39080-0.555305.995205.02070HepG2PUM2
METTL21AENSG00000144401.10373.25040580.98370-0.638405.328004.52360HepG2PUS1
METTL21AENSG00000144401.10635.68930930.57270-0.549805.769404.82830HepG2RBM25
METTL21AENSG00000144401.10596.467701053.62470-0.8208015.3738014.29290HepG2NELFE
METTL21AENSG00000144401.10699.83580981.25690-0.487606.303505.42600HepG2RECQL
METTL21AENSG00000144401.10224.75640465.91670-1.0517011.4608010.31560HepG2RPS19
METTL21AENSG00000144401.10189.84470369.12970-0.959306.222805.09300HepG2RRP9
METTL21AENSG00000144401.10558.72730811.48030-0.538403.268902.53520HepG2SF3A3
METTL21AENSG00000144401.10682.05470985.70760-0.531307.244006.36000HepG2SF3B4
METTL21AENSG00000144401.10696.02390833.70450-0.260402.121801.66480HepG2SRFBP1
METTL21AENSG00000144401.10617.318701028.84030-0.7369013.2502012.38160HepG2SRSF1
METTL21AENSG00000144401.10654.07750836.99490-0.355803.773603.15100HepG2SRSF9
METTL21AENSG00000144401.10894.10660723.842600.304702.871202.35120HepG2SSB
METTL21AENSG00000144401.10723.72200875.84960-0.275202.635102.02460HepG2SUCLG1
METTL21AENSG00000144401.10456.73080736.27310-0.688902.832401.75380HepG2TBRG4
METTL21AENSG00000144401.10267.11670450.66600-0.754608.447007.54730HepG2TRIM56
METTL21AENSG00000144401.10616.95440806.52140-0.386502.051501.33670HepG2UBE2L3
METTL21AENSG00000144401.10586.30620719.66020-0.295702.377701.72230HepG2UPF1
METTL21AENSG00000144401.10502.56350694.80180-0.467304.720303.97150HepG2UTP3
METTL21AENSG00000144401.10480.85950791.48670-0.7189012.5962011.64220HepG2ZNF622
METTL21AENSG00000144401.10402.25450701.89030-0.803107.918907.01130K562AQR
METTL21AENSG00000144401.10247.21110434.20000-0.812607.044705.78480K562CPSF6
METTL21AENSG00000144401.10183.70940309.05850-0.750504.476603.29860K562EFTUD2
METTL21AENSG00000144401.10200.93460371.84370-0.888007.496006.15040K562EIF4A3
METTL21AENSG00000144401.10329.10850441.76520-0.424702.235101.46420K562FMR1
METTL21AENSG00000144401.10305.48400414.56360-0.440502.364901.62920K562GPKOW
METTL21AENSG00000144401.10196.51540391.55800-0.994608.689807.68160K562HNRNPC
METTL21AENSG00000144401.10364.32600469.76040-0.366702.084301.34960K562MAGOH
METTL21AENSG00000144401.10232.53910427.40750-0.878106.862704.06510K562PABPC4
METTL21AENSG00000144401.10211.77900300.75000-0.506002.221101.54520K562PRPF8
METTL21AENSG00000144401.10454.36890569.53900-0.325902.190701.45790K562SF3A3
METTL21AENSG00000144401.10307.51940420.43300-0.451202.938602.05570K562SF3B4
METTL21AENSG00000144401.10274.09010447.38540-0.706905.813604.79700K562SRSF1
METTL21AENSG00000144401.10350.66950452.83580-0.368901.895601.30200K562TARDBP
METTL21AENSG00000144401.10186.84420358.76830-0.941207.240105.55300K562TRIM56
METTL21AENSG00000144401.10405.45030523.67820-0.369202.301301.50140K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for METTL21A is not available on ENCORE database.





4 RBPs can affect the splicing of METTL21A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMETTL21AENSG00000144401.10chr2-2084853642084854182084774462084781672084865292084866410.095000.000970.08505includedHepG2DDX59
SEMETTL21AENSG00000144401.10chr2-208485364208485418208477446208478167208486529208486641-0.088000.007120.07002excludedHepG2U2AF2
SEMETTL21AENSG00000144401.10chr2-208486529208486641208477566208478167208488952208489290-0.109000.000940.02613excludedK562RBM15
SEMETTL21AENSG00000144401.10chr2-208446761208446884208446517208446670208486529208486641-0.196000.001420.02571excludedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for METTL21A is not avaliable on ENCORE database.