METTL15

General Information

Gene Name       : METTL15
Gene ID             : ENSG00000169519.20
Essential Gene : No

Functions

Localization

Domains (AlphaFold: METTL15)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878METTL15ENSG00000169519.207.166.496.83ENCSR000AEF
HepG2METTL15ENSG00000169519.203.948.176.05ENCSR985KAT
K562METTL15ENSG00000169519.207.308.157.72ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for METTL15 is not avaliable on ENCORE database.



Proteins bound to RNA
  • METTL15 RNA is bound by 16 proteins.  







eCLIP assay for METTL15 is not avaliable on ENCORE database.





16 proteins are bound to METTL15 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr112831844328318508+3'-UTR,CDS,intron-Proximal4.870315.01842HepG2PRPF8
chr112814735028147427+3'-UTR,intron-Distal,polyA_site3.573989.06665K562KHSRP
chr112814736728147472+3'-UTR,intron-Distal,polyA_site3.365064.31768HepG2KHSRP
chr112831190228312008+3'-UTR,CDS,intron-Proximal4.872826.37937HepG2BCLAF1
chr112814705428147108+3'-UTR,intron-Distal,intron-Proximal4.291623.35169HepG2U2AF2
chr112813189728131991+5'-UTR,intron-Proximal3.998736.79646HepG2PRPF8
chr112813167128131776+5'-UTR,intron-Proximal4.253896.48405K562AQR
chr112814362328143698+CDS,intron-Distal,intron-Proximal4.296314.53660HepG2KHSRP
chr112827291128272998+intron-Distal4.7469110.10565HepG2QKI
chr112832638928326463+intron-Distal3.822323.16986HepG2QKI
chr112820771828207825+intron-Distal3.233594.30679K562KHSRP
chr112827857828278635+intron-Distal4.314493.78432HepG2MATR3
chr112815435528154392+intron-Distal3.617815.32884K562KHSRP
chr112821569328215782+intron-Distal4.326014.07628HepG2PTBP1
chr112815423028154338+intron-Distal3.446889.78720K562KHSRP
chr112831201528312111+intron-Distal,intron-Proximal3.866935.03298HepG2HNRNPL
chr112816701528167085+intron-Distal4.013507.08005HepG2QKI
chr112814261828142670+intron-Distal4.193684.29306HepG2KHSRP
chr112828138928281527+intron-Distal5.059906.43853HepG2MATR3
chr112814377128143843+intron-Distal,intron-Proximal3.8982912.40486K562KHSRP
chr112814742728147487+intron-Distal3.327469.06665K562KHSRP
chr112813956228139635+intron-Distal3.686383.24242HepG2HNRNPC
chr112833090328331041+intron-Distal3.504283.76275K562PTBP1
chr112814262228142677+intron-Distal4.3419014.01968K562KHSRP
chr112820446828204530+intron-Distal4.719036.08869K562EXOSC5
chr112833090828331051+intron-Distal5.3459810.34143K562QKI
chr112813772128137836+intron-Distal3.645338.98001K562KHSRP
chr112819407728194184+intron-Distal4.279628.76637HepG2QKI
chr112818722628187274+intron-Distal4.044974.07352K562KHSRP
chr112833106428331108+intron-Distal3.253573.35585HepG2QKI
chr112816996028170048+intron-Distal3.261376.40629HepG2PTBP1
chr112827976228279827+intron-Distal4.335404.66737HepG2MATR3
chr112816645628166552+intron-Distal3.416704.45128HepG2HNRNPL
chr112816996228170042+intron-Distal4.2669612.33192K562PTBP1
chr112815340928153459+intron-Distal3.390654.56724K562KHSRP
chr112814346728143497+intron-Distal3.781118.67954K562KHSRP
chr112814349728143521+intron-Distal4.259098.11138K562KHSRP
chr112827884028278886+intron-Distal3.829813.04224HepG2SUGP2
chr112813734628137405+intron-Distal4.367325.73195K562HNRNPL
chr112813753028137590+intron-Distal4.178973.71677HepG2HNRNPL
chr112827858428278639+intron-Distal4.114043.54208HepG2SUGP2
chr112814748028147579+intron-Distal4.371866.86842HepG2U2AF2
chr112827107828271168+intron-Distal4.182843.90026K562KHSRP
chr112820511228205145+intron-Distal4.375503.89085K562EXOSC5
chr112815401328154075+intron-Distal4.3460711.37309K562KHSRP
chr112814267728142741+intron-Distal4.0916411.66098K562KHSRP
chr112828140128281458+intron-Distal4.214504.36036HepG2SUGP2
chr112814492328144977+intron-Distal3.279743.70059HepG2U2AF2
chr112814529628145361+intron-Distal,intron-Proximal5.8185517.61906K562KHSRP
chr112825333628253441+intron-Distal3.870513.47525K562MATR3
chr112824837028248459+intron-Distal6.9197732.17965HepG2QKI
chr112814340828143467+intron-Distal3.092476.28283K562KHSRP
chr112815229428152370+intron-Distal3.189605.22328K562KHSRP
chr112814955228149604+intron-Distal4.172604.76003K562KHSRP
chr112824838328248457+intron-Distal6.2456215.08232K562QKI
chr112815133528151395+intron-Distal3.512786.18396K562KHSRP
chr112814506528145120+intron-Distal4.259479.29751K562KHSRP
chr112814992828150003+intron-Distal3.935226.62503K562KHSRP
chr112813749528137595+intron-Distal3.0681510.64043K562AGGF1
chr112826864128268723+intron-Distal4.546344.58794K562KHSRP
chr112815439228154442+intron-Distal5.1633610.47957K562KHSRP
chr112827975628279843+intron-Distal3.939837.23308HepG2SUGP2
chr112817089328170989+intron-Distal4.139653.60944K562TARDBP
chr112819410628194179+intron-Distal4.829884.38664K562QKI
chr112828143528281549+intron-Distal3.197763.45178K562MATR3
chr112815396428154028+intron-Distal4.296323.12827HepG2U2AF2
chr112828154928281735+intron-Distal3.518543.45178K562MATR3
chr112814423128144256+intron-Distal4.120294.10688K562KHSRP
chr112814340528143475+intron-Distal3.169374.89227HepG2KHSRP
chr112832988128329976+intron-Distal3.524603.30744K562PTBP1
chr112817196928172076+intron-Distal4.322335.93583K562QKI
chr112814372828143768+intron-Distal,intron-Proximal3.882127.69621K562KHSRP
chr112826777728267874+intron-Distal3.901583.26999K562KHSRP
chr112827636728276437+intron-Distal4.401034.66737HepG2MATR3
chr112814559128145622+intron-Distal4.686516.80456K562KHSRP
chr112833209328332199+intron-Distal3.470054.23286HepG2QKI
chr112817760828177693+intron-Distal3.907406.59336K562KHSRP
chr112814520028145296+intron-Distal4.1394515.25295K562KHSRP
chr112828152728281599+intron-Distal4.478285.01910HepG2MATR3
chr112815241128152493+intron-Distal3.542237.64049K562KHSRP
chr112820400928204053+intron-Distal4.258273.89085K562EXOSC5
chr112833094728331049+intron-Distal4.5840116.87745HepG2QKI
chr112815313428153225+intron-Distal4.3047221.19882K562KHSRP
chr112814223928142370+intron-Distal3.396754.24981K562MATR3
chr112814487928144921+intron-Distal3.645185.70834K562RBFOX2
chr112824312128243180+intron-Distal3.981523.28572K562HNRNPM
chr112825332128253432+intron-Distal4.244264.07628HepG2PTBP1
chr112814352128143554+intron-Distal3.470034.52210K562KHSRP
chr112814549328145515+intron-Distal,intron-Proximal4.370884.96658K562KHSRP
chr112833090428330947+intron-Distal4.879765.58765HepG2QKI
chr112814411928144144+intron-Distal3.778043.45805K562KHSRP
chr112818431728184390+intron-Distal3.546345.61949K562KHSRP
chr112818780828187896+intron-Distal3.274483.35377HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for METTL15 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for METTL15 is not available on ENCORE database.

  • 71 RBPs can affect the levels of METTL15.  








The Knockdown/knockout RNA-Seq assay for METTL15 is not available on ENCORE database.





71 RBPs can affect the gene expression of METTL15 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
METTL15ENSG00000169519.15334.99560529.27200-0.659903.997503.37540HepG2AKAP1
METTL15ENSG00000169519.15304.36020437.92200-0.524902.926002.11940HepG2ASCC1
METTL15ENSG00000169519.15187.19850344.53770-0.880105.441704.11240HepG2BCCIP
METTL15ENSG00000169519.15260.18260425.62490-0.710104.018902.83080HepG2CCAR1
METTL15ENSG00000169519.15127.30810262.08850-1.041706.484605.46490HepG2CPSF6
METTL15ENSG00000169519.15190.93710268.47780-0.491702.542101.56990HepG2YBX3
METTL15ENSG00000169519.15364.77580490.08890-0.426003.761002.91920HepG2DAZAP1
METTL15ENSG00000169519.15337.67600506.98930-0.586303.656102.94690HepG2DDX3X
METTL15ENSG00000169519.15199.32210338.76280-0.765204.318803.37560HepG2DDX55
METTL15ENSG00000169519.15326.50490435.54550-0.415701.892101.37180HepG2DDX6
METTL15ENSG00000169519.15150.83090261.29870-0.792806.165005.24810HepG2DNAJC2
METTL15ENSG00000169519.15260.08290418.66950-0.686804.399403.66110HepG2EIF2S1
METTL15ENSG00000169519.1585.98900194.84940-1.180105.602404.34610HepG2EIF3D
METTL15ENSG00000169519.15269.88670462.66400-0.777605.355004.46670HepG2EIF4A3
METTL15ENSG00000169519.15301.77260450.49690-0.578102.724002.03980HepG2EIF4B
METTL15ENSG00000169519.15305.34000466.85390-0.612603.885003.07430HepG2FXR1
METTL15ENSG00000169519.15310.83600433.05160-0.478402.463701.83400HepG2G3BP1
METTL15ENSG00000169519.15150.13200266.14750-0.826004.707603.89430HepG2HNRNPA1
METTL15ENSG00000169519.15171.97530296.04140-0.783604.545303.67180HepG2HNRNPC
METTL15ENSG00000169519.15179.07070261.40870-0.545802.147001.50880HepG2HNRNPF
METTL15ENSG00000169519.15272.04910438.55960-0.688904.656003.76880HepG2HNRNPK
METTL15ENSG00000169519.15338.40160446.46210-0.399803.151902.43560HepG2HNRNPL
METTL15ENSG00000169519.15180.81080294.08410-0.701705.210104.39870HepG2HNRNPU
METTL15ENSG00000169519.15233.44150440.17900-0.915007.373206.32640HepG2IGF2BP2
METTL15ENSG00000169519.15189.15480449.22330-1.2479010.890009.24190HepG2LARP4
METTL15ENSG00000169519.15299.92670467.01710-0.638904.116703.31900HepG2MAGOH
METTL15ENSG00000169519.15164.72160243.05350-0.561202.391001.63600HepG2MSI2
METTL15ENSG00000169519.15248.09480480.67980-0.954207.826506.78680HepG2NCBP2
METTL15ENSG00000169519.15326.07220485.96610-0.575705.119504.08730HepG2NOL12
METTL15ENSG00000169519.15186.18290311.12610-0.740803.033501.88420HepG2NONO
METTL15ENSG00000169519.15190.34180262.29920-0.462602.358401.67280HepG2PPIL4
METTL15ENSG00000169519.15222.92300338.90500-0.604302.617201.42760HepG2PRPF6
METTL15ENSG00000169519.15338.25620435.23300-0.363702.311901.80330HepG2PTBP1
METTL15ENSG00000169519.15315.36100463.87100-0.556704.094103.38460HepG2PUF60
METTL15ENSG00000169519.15390.69390492.38890-0.333802.320401.76780HepG2PUM1
METTL15ENSG00000169519.15363.70040471.34530-0.374002.175901.61050HepG2QKI
METTL15ENSG00000169519.15305.25670427.78470-0.486902.990702.29370HepG2RBM25
METTL15ENSG00000169519.15181.47830288.17120-0.667102.771701.70990HepG2RCC2
METTL15ENSG00000169519.15365.86850484.36360-0.404802.644102.11270HepG2NELFE
METTL15ENSG00000169519.15342.36600451.13500-0.398002.553201.95750HepG2RECQL
METTL15ENSG00000169519.15188.49200281.70900-0.579701.972801.38420HepG2RPLP0
METTL15ENSG00000169519.15106.89970189.57870-0.826503.930503.21000HepG2RPS19
METTL15ENSG00000169519.15217.76480327.30910-0.587902.789701.98640HepG2RPS2
METTL15ENSG00000169519.15125.76820190.30070-0.597502.251201.39930HepG2SERBP1
METTL15ENSG00000169519.15224.39670305.41110-0.444702.637802.00640HepG2SMN1
METTL15ENSG00000169519.15200.39980317.23100-0.662703.317202.25840HepG2SMNDC1
METTL15ENSG00000169519.15203.78440301.96380-0.567302.304601.40060HepG2SRSF3
METTL15ENSG00000169519.15347.94470457.96830-0.396402.934302.29050HepG2SRSF5
METTL15ENSG00000169519.15275.61740443.09540-0.685006.644205.91400HepG2SSB
METTL15ENSG00000169519.15405.42470520.86760-0.361502.982702.34160HepG2SUCLG1
METTL15ENSG00000169519.15213.98200337.21660-0.656203.334402.59950HepG2SUPV3L1
METTL15ENSG00000169519.15197.31430276.35160-0.486002.058101.42040HepG2TARDBP
METTL15ENSG00000169519.15143.90570226.01440-0.651302.984901.95150HepG2TFIP11
METTL15ENSG00000169519.15165.27020285.75180-0.789905.381704.73070HepG2TIAL1
METTL15ENSG00000169519.15301.68420453.13230-0.586904.431703.29460HepG2TUFM
METTL15ENSG00000169519.15233.95580479.60050-1.035607.869506.42700HepG2UBE2L3
METTL15ENSG00000169519.15161.75490308.74360-0.932604.723303.39450HepG2UPF2
METTL15ENSG00000169519.15158.49320265.13900-0.742304.935104.17490HepG2UTP3
METTL15ENSG00000169519.15193.54630331.95330-0.778304.704503.76800HepG2XRN2
METTL15ENSG00000169519.15198.86470357.49390-0.846105.427404.33660K562CPSF6
METTL15ENSG00000169519.15359.67990509.13130-0.501303.655002.43520K562DDX3X
METTL15ENSG00000169519.15272.41840380.44470-0.481902.406701.55670K562EFTUD2
METTL15ENSG00000169519.15417.35660559.26150-0.422203.520502.13920K562EIF2S1
METTL15ENSG00000169519.15392.52120531.92580-0.438502.833002.00190K562EIF4A3
METTL15ENSG00000169519.15296.01750479.03680-0.694506.927104.97170K562EIF4B
METTL15ENSG00000169519.15268.76810425.26420-0.662004.703203.57580K562FIP1L1
METTL15ENSG00000169519.15260.23370363.69970-0.482902.450301.64400K562FMR1
METTL15ENSG00000169519.15443.91600553.18200-0.317502.005801.47460K562FXR1
METTL15ENSG00000169519.15494.86700642.93200-0.377602.243001.55900K562GRSF1
METTL15ENSG00000169519.15183.36500382.57650-1.061009.427708.37820K562HNRNPC
METTL15ENSG00000169519.15240.01720341.62700-0.509302.685801.56480K562HNRNPF
METTL15ENSG00000169519.15448.66690655.11190-0.546105.543704.26520K562HNRNPU
METTL15ENSG00000169519.15523.83030701.35480-0.421003.213002.30180K562MAGOH
METTL15ENSG00000169519.15457.43380699.95550-0.613706.306904.83220K562MATR3
METTL15ENSG00000169519.15239.09040374.79710-0.648603.788102.21920K562NONO
METTL15ENSG00000169519.15221.74230343.01590-0.629403.950102.84260K562PSIP1
METTL15ENSG00000169519.15269.88340484.38650-0.843808.086005.65360K562RBM25
METTL15ENSG00000169519.15182.22230312.93850-0.780205.344703.95780K562RCC2
METTL15ENSG00000169519.15398.85590530.99060-0.412802.866701.99560K562SF3B4
METTL15ENSG00000169519.15209.89450296.65930-0.499102.304601.38650K562SRFBP1
METTL15ENSG00000169519.15468.28820630.81430-0.429802.910601.82940K562SRSF5
METTL15ENSG00000169519.15442.60600676.07720-0.611205.137304.15870K562TARDBP
METTL15ENSG00000169519.15438.77190652.14290-0.571705.279204.09630K562TIA1
METTL15ENSG00000169519.15220.74170329.92630-0.579802.894101.93670K562TIAL1
METTL15ENSG00000169519.15488.09410639.85770-0.390602.567201.52080K562TRA2A
METTL15ENSG00000169519.15239.26310350.48270-0.550703.094302.08170K562TRIM56
METTL15ENSG00000169519.15833.823601113.95690-0.417903.996302.30100K562UBE2L3
METTL15ENSG00000169519.15386.23970501.01590-0.375402.743301.90020K562WDR43
METTL15ENSG00000169519.15269.85130386.30120-0.517602.783601.57400K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for METTL15 is not available on ENCORE database.





10 RBPs can affect the splicing of METTL15 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMETTL15ENSG00000169519.15chr11+283117522831194428232608282327452831829928318478-0.221000.000710.08475excludedK562HNRNPM
SEMETTL15ENSG00000169519.15chr11+283496412834971228318299283184782835194228355054-0.111000.001030.06496excludedK562HNRNPL
SEMETTL15ENSG00000169519.15chr11+2834964128349712283182992831847828351942283550540.119000.000150.08585includedK562PUM2
SEMETTL15ENSG00000169519.15chr11+2834964128349712283182992831847828351942283550540.116000.000680.09385includedK562EIF4G2
SEMETTL15ENSG00000169519.15chr11+283496412834971228318299283184782835194228355054-0.145000.000210.00792excludedK562RBM15
SEMETTL15ENSG00000169519.15chr11+283496412834971228318299283184782835194228355054-0.164000.000000.00032excludedK562AGGF1
SEMETTL15ENSG00000169519.15chr11+2834964128349712283182992831847828351942283550540.319000.000120.00800includedHepG2HNRNPU
A3SSMETTL15ENSG00000169519.15chr11+283182992831847828318343283184782831175228311944-0.422000.000690.06592shorterHepG2SRSF1
A3SSMETTL15ENSG00000169519.15chr11+283182992831847828318343283184782831175228311944-0.347000.000720.09187shorterHepG2SFPQ
MXEMETTL15ENSG00000169519.15chr11+2831829928318478283496412834971228311752283119442835194228355054-0.071000.000530.048402includedK562PUM1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for METTL15 is not avaliable on ENCORE database.