MED17

General Information

Gene Name       : MED17
Gene ID             : ENSG00000042429.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MED17)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MED17ENSG00000042429.1122.7719.6021.19ENCSR000AEF
HepG2MED17ENSG00000042429.1114.0125.6119.81ENCSR985KAT
K562MED17ENSG00000042429.1115.9418.0316.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MED17 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MED17 RNA is bound by 11 proteins.  







eCLIP assay for MED17 is not avaliable on ENCORE database.





11 proteins are bound to MED17 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr119354548893545521+3'-UTR4.885066.34419K562PUM2
chr119354539693545478+3'-UTR6.2453025.13051K562PUM2
chr119353499593535066+3'-UTR,CDS,intron-Proximal3.234403.94979HepG2BCLAF1
chr119353506693535146+3'-UTR,CDS,intron-Proximal4.698864.34038HepG2BCLAF1
chr119353495693535046+3'-UTR,CDS,intron-Proximal3.919425.16342K562SF3B4
chr119353498993535038+3'-UTR,CDS,intron-Proximal3.907393.00996K562BUD13
chr119352802193528115+5'-UTR,CDS,intron-Distal,intron-Proximal3.591394.94119K562SF3B4
chr119352818693528317+5'-UTR,CDS,intron-Distal,intron-Proximal4.249335.05356HepG2PRPF8
chr119352961993529707+5'-UTR,CDS,intron-Proximal3.485655.56491HepG2BCLAF1
chr119351751993517580+5'-UTR5.036356.89039K562RBM15
chr119352806993528161+5'-UTR,CDS,intron-Distal,intron-Proximal4.720394.70478HepG2BCLAF1
chr119352698493527085+5'-UTR,CDS,intron-Proximal4.788997.46483HepG2PRPF8
chr119351763493517684+5'-UTR,CDS4.684077.70265K562RBM15
chr119352952093529589+5'-UTR,CDS,intron-Proximal4.195695.16342K562SF3B4
chr119352816193528225+5'-UTR,CDS,intron-Distal4.319363.71570HepG2BCLAF1
chr119354079593540854+CDS,intron-Distal,intron-Proximal3.842334.52312K562AQR
chr119354300293543080+CDS,intron-Distal,intron-Proximal4.635684.85612K562PRPF8
chr119352385193523970+CDS,intron-Proximal4.381335.42152HepG2GRWD1
chr119351781493517923+CDS3.055844.63108HepG2PPIG
chr119351784493517969+CDS,intron-Proximal3.344286.16215HepG2BUD13
chr119351782793517964+CDS,intron-Proximal4.050304.07395K562SRSF1
chr119352689293526937+CDS,intron-Proximal3.461593.27569HepG2BCLAF1
chr119352094593521026+intron-Distal3.831493.66668K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MED17 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MED17 is not available on ENCORE database.

  • 70 RBPs can affect the levels of MED17.  








The Knockdown/knockout RNA-Seq assay for MED17 is not available on ENCORE database.





70 RBPs can affect the gene expression of MED17 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MED17ENSG00000042429.6862.43320632.536600.447205.538504.73720HepG2ACO1
MED17ENSG00000042429.61423.50850761.266400.902909.982009.03790HepG2AKAP1
MED17ENSG00000042429.6399.69780587.58430-0.555903.201302.23280HepG2BCLAF1
MED17ENSG00000042429.6489.77140958.40990-0.9685012.4604011.11710HepG2CPSF6
MED17ENSG00000042429.61075.29670822.131600.387204.021103.27270HepG2CELF1
MED17ENSG00000042429.6676.15440884.12380-0.386903.683502.84820HepG2DAZAP1
MED17ENSG00000042429.61058.57240729.225500.537604.226103.46560HepG2DDX3X
MED17ENSG00000042429.6441.22500548.70190-0.314502.455901.83540HepG2DNAJC2
MED17ENSG00000042429.6586.13150400.094000.550803.774902.72870HepG2EIF3D
MED17ENSG00000042429.6417.37270665.48120-0.673105.018804.16130HepG2EIF4A3
MED17ENSG00000042429.61141.52540647.961300.816906.702905.66460HepG2EIF4B
MED17ENSG00000042429.6744.512301086.49960-0.545304.158603.38550HepG2GPKOW
MED17ENSG00000042429.6384.41090558.87050-0.539903.854703.11050HepG2HNRNPA1
MED17ENSG00000042429.6314.18750621.64780-0.9845010.774309.48360HepG2HNRNPC
MED17ENSG00000042429.6621.23650775.89180-0.320702.605701.90940HepG2HNRNPF
MED17ENSG00000042429.6671.36660805.40870-0.262602.465801.82510HepG2HNRNPL
MED17ENSG00000042429.6584.228101036.86050-0.827609.283408.20690HepG2HNRNPLL
MED17ENSG00000042429.6438.03230617.53720-0.495505.027204.23020HepG2HNRNPU
MED17ENSG00000042429.6612.92810764.03550-0.317902.132001.49050HepG2IGF2BP1
MED17ENSG00000042429.6806.83970633.132800.349702.018601.43320HepG2IGF2BP2
MED17ENSG00000042429.6978.55610594.194100.719602.334801.43920HepG2IGF2BP3
MED17ENSG00000042429.6681.388301057.31600-0.633904.067602.88200HepG2MTPAP
MED17ENSG00000042429.6823.27260559.502400.557103.139202.03450HepG2PCBP2
MED17ENSG00000042429.6623.77370836.83960-0.423903.570702.90510HepG2PUF60
MED17ENSG00000042429.61171.21290888.299700.398805.578004.79720HepG2PUM1
MED17ENSG00000042429.61077.32360887.677200.279201.930601.36420HepG2PUM2
MED17ENSG00000042429.61052.01500539.983300.962106.738605.66300HepG2RAVER1
MED17ENSG00000042429.61298.28620928.113700.484106.687205.96570HepG2RBM22
MED17ENSG00000042429.6841.57020616.576900.448703.667102.89750HepG2RBM25
MED17ENSG00000042429.6809.56050615.095500.396202.788901.79330HepG2RBM27
MED17ENSG00000042429.6518.82460389.266700.414402.692202.08460HepG2RPS19
MED17ENSG00000042429.6688.97940507.415200.441202.671301.89680HepG2RRP9
MED17ENSG00000042429.6449.44140549.93970-0.291102.019301.45530HepG2SAFB2
MED17ENSG00000042429.61596.96390771.068901.0503012.0905010.62340HepG2SF3A3
MED17ENSG00000042429.61172.22860653.115200.8437016.9594015.68600HepG2SF3B4
MED17ENSG00000042429.6776.69360641.315000.276202.448901.83840HepG2SMN1
MED17ENSG00000042429.61992.495101048.280500.9265032.1274030.90960HepG2SRFBP1
MED17ENSG00000042429.6990.56270681.685600.539007.025906.35550HepG2SRSF1
MED17ENSG00000042429.6589.34840762.27570-0.371203.426602.66360HepG2SRSF7
MED17ENSG00000042429.6707.49920554.565800.351303.083602.50680HepG2SRSF9
MED17ENSG00000042429.6659.191201010.43970-0.616206.083405.06730HepG2TARDBP
MED17ENSG00000042429.6428.13550605.41870-0.499905.072204.35510HepG2TRIM56
MED17ENSG00000042429.61085.50420651.917300.735508.673507.55490HepG2U2AF1
MED17ENSG00000042429.6521.92660683.81850-0.389803.681202.89350HepG2UPF1
MED17ENSG00000042429.6998.10540660.202500.596209.054308.07290HepG2UTP3
MED17ENSG00000042429.6684.02340556.635200.297202.435101.79880HepG2ZC3H8
MED17ENSG00000042429.6772.84290577.899500.419302.111401.53760K562AKAP8L
MED17ENSG00000042429.63215.88610917.743501.8090060.2761057.89750K562AQR
MED17ENSG00000042429.61092.13700787.500900.471703.509601.87380K562BUD13
MED17ENSG00000042429.61420.05390780.508200.863406.198804.55150K562CNOT7
MED17ENSG00000042429.61813.417901424.448900.348203.921302.75020K562CELF1
MED17ENSG00000042429.61215.28110896.796400.438305.993105.08620K562DDX47
MED17ENSG00000042429.6776.18370621.977600.319402.271201.48840K562DKC1
MED17ENSG00000042429.6407.85180281.365400.535503.096301.67420K562DNAJC21
MED17ENSG00000042429.6974.77670758.924600.361002.402701.60360K562FMR1
MED17ENSG00000042429.6861.70950643.275700.421702.405701.55800K562FTO
MED17ENSG00000042429.6740.99020476.328100.637407.917906.96310K562FXR1
MED17ENSG00000042429.6735.65940505.489400.541303.229902.45700K562G3BP2
MED17ENSG00000042429.6276.79820514.37480-0.894007.693906.74520K562HNRNPC
MED17ENSG00000042429.6792.37300613.360800.369302.141601.42610K562KIF1C
MED17ENSG00000042429.6813.78770608.076300.420302.212901.38880K562KRR1
MED17ENSG00000042429.6878.92390687.110000.355102.338501.51400K562MBNL1
MED17ENSG00000042429.6780.35780481.608600.696204.665203.42410K562NAA15
MED17ENSG00000042429.61610.632901267.277400.345802.993001.43490K562NOL12
MED17ENSG00000042429.61114.61340749.840600.571803.177101.84140K562PABPC1
MED17ENSG00000042429.6721.88750510.683000.499203.941102.76820K562PCBP2
MED17ENSG00000042429.61029.02670694.434500.567303.396801.39000K562PPIL4
MED17ENSG00000042429.6802.11210470.607100.769207.781606.51870K562PRPF8
MED17ENSG00000042429.61758.357501264.169700.475905.264804.14220K562PUF60
MED17ENSG00000042429.61782.108601344.487100.406405.114803.63080K562PUM1
MED17ENSG00000042429.61536.675301317.490100.221902.155401.30670K562PUM2
MED17ENSG00000042429.61013.87470573.250500.822507.499506.65190K562PUS1
MED17ENSG00000042429.6706.30020558.436200.338802.243201.69990K562RBM15
MED17ENSG00000042429.6772.18230534.767700.529904.631303.51140K562RBM22
MED17ENSG00000042429.61167.54970703.686600.7304012.9669011.30660K562SF3A3
MED17ENSG00000042429.6916.00850677.280500.435502.390901.49150K562SF3B1
MED17ENSG00000042429.6814.44770525.407100.632307.526206.07200K562SF3B4
MED17ENSG00000042429.6877.84280558.310800.652802.479701.34360K562SNRNP200
MED17ENSG00000042429.6974.22180546.593200.8337012.1413010.65490K562SRSF1
MED17ENSG00000042429.6729.40080553.238000.398702.655901.96090K562TARDBP
MED17ENSG00000042429.6751.36670489.744000.617404.606503.12260K562U2AF1
MED17ENSG00000042429.6777.37000505.877300.619706.983905.71530K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MED17 is not available on ENCORE database.





13 RBPs can affect the splicing of MED17 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMED17ENSG00000042429.6chr11+935307009353088593529575935297069353500093535142-0.181000.000010.00012excludedK562AQR
SEMED17ENSG00000042429.6chr11+935428829354304293540683935408019354501893545394-0.137000.001730.03508excludedK562U2AF1
A3SSMED17ENSG00000042429.6chr11+9354066693540801935406839354080193535000935351380.080000.000050.00047longerK562AQR
RIMED17ENSG00000042429.6chr11+935268939352720193526893935270309352711693527201-0.098000.004440.06899excludedHepG2PCBP2
RIMED17ENSG00000042429.6chr11+9352689393527201935268939352703093527116935272010.193000.000000.00000includedK562PUS1
RIMED17ENSG00000042429.6chr11+935268939352720193526893935270309352711693527201-0.101000.005000.05363excludedHepG2PRPF8
RIMED17ENSG00000042429.6chr11+935268939352720193526893935270309352711693527201-0.143000.002460.08813excludedK562NCBP2
RIMED17ENSG00000042429.6chr11+9352689393527201935268939352703093527116935272010.201000.000020.00130includedHepG2MATR3
RIMED17ENSG00000042429.6chr11+935268939352720193526893935270309352711693527201-0.129000.000370.07285excludedHepG2EIF3D
RIMED17ENSG00000042429.6chr11+9352689393527201935268939352703093527116935272010.129000.000000.00000includedK562BUD13
RIMED17ENSG00000042429.6chr11+9352689393527201935268939352703093527116935272010.071000.000100.03396includedK562PUM2
RIMED17ENSG00000042429.6chr11+935268939352720193526893935270309352711693527201-0.132000.000000.00004excludedHepG2RBM22
RIMED17ENSG00000042429.6chr11+9352689393527201935268939352703093527116935272010.119000.003870.04024includedHepG2HNRNPK
RIMED17ENSG00000042429.6chr11+9352689393527201935268939352703093527116935272010.126000.000060.00049includedK562AQR
RIMED17ENSG00000042429.6chr11+935268939352720193526893935270309352711693527201-0.122000.003110.04684excludedK562FXR1
MXEMED17ENSG00000042429.6chr11+93535000935351389354288293543042935295759352970693545018935478610.117000.000370.003801includedK562AQR
MXEMED17ENSG00000042429.6chr11+93540683935408019354288293543042935295759352970693545018935478610.103000.001010.009191includedK562AQR
MXEMED17ENSG00000042429.6chr11+93540683935408019354288293542988935295759352970693545018935453940.220000.003040.023681includedK562AQR
MXEMED17ENSG00000042429.6chr11+9353500093535138935428389354304293530700935308859354501893547861-0.108000.013620.081102includedK562AQR
MXEMED17ENSG00000042429.6chr11+9353500093535138935406399354080193530700935308859354501893547861-0.101000.006770.046222includedK562AQR
MXEMED17ENSG00000042429.6chr11+9353500093535138935428829354304293530700935308859354501893547861-0.108000.013620.081102includedK562AQR
MXEMED17ENSG00000042429.6chr11+9353070093530885935406399354080193529575935297069354501893547861-0.085000.015210.088532includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MED17 is not avaliable on ENCORE database.